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Assignee: Meiji Seika Kaisha, Ltd.


Location: Tokyo, JP
No. of patents: 309

1                
NumberTitleIssue Date
809770810a-Azalide compound
[Object]: To provide a compound having a novel structure effective against Hemophilus influenzae and erythromycin resistant bacteria (for example, resistant pneumococci and streptococci) as well as against conventional erythromycin sensitive bacteria. ...
01/17/2012
8058247Antibacterial agent and therapeutic agent for johne's disease containing the same
An antibacterial agent having high antibacterial activity against Mycobacterium avium subsp. paratuberculosis is provided. Specifically, the antibacterial agent of the present invention having high antibacterial activity against Mycobacterium avium...
11/15/2011
8030052Midecamycin hyper producing strain
A midecamycin hyper producing strain having improved productivity of midecamycin which is a member of macrolide antibiotics, and a method for producing midecamycins using the strain are provided. The midecamycin producing actinomycetes comprises a midecamycin biosyn...
10/04/2011
7955789Adhesion-preventing material and process for preventing adhesion
An object of the present invention is to provide an adhesion-preventing material which is capable of effectively preventing the surfaces of organs from adhesion, and which can be absorbed in the body with high safety and produced with ease and has high practical uti...
06/07/2011
7910089Sialogogue, oral composition and food product containing the same
A sialogogue characterized by comprising polyglutamic acid or its salt. This sialogogue is blended into an oral composition and a food product. This sialogogue is capable of rendering the oral mucosa pleasant even in the case of severe xerostomia. ...
03/22/2011
7871982Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient
This invention provides compounds of formula (I) or its pharmacologically acceptable salt or solvate, wherein A represents aryl or a monocyclic or bicyclic heterocyclic group, R1 represents a halide, nitro, substituted C1-6 alkyl, optionally su...
01/18/2011
7863248Tyrosinase activity inhibitor and ameliorant for facial blood flow
A tyrosinase activity inhibitor and an ameliorant for facial blood flow that are excellent in terms of safety, and medicinal compositions, food compositions, and cosmetic preparations that contain the inhibitor and the ameliorant as active ingredients are provided. ...
01/04/2011
7858612Therapeutic agent for inflammatory bowel diseases
The present invention relates to a method for maintaining the remission of or treating inflammatory bowel diseases, which comprises administering a maintenance therapeutically effective amount or a therapeutically effective amount of 7,8-dimethoxy-4(5H),10-dioxo-1H-...
12/28/2010
7790430Cellulase resistant to surfactants
Disclosed is a novel cellulose having an amino acid sequence in which the 162nd and/or 166th amino acid residues in the amino acid sequence of cellulose NCE5 are substituted. Further, a polynucleotide encoding the novel cellulose, an expression vector containing the...
09/07/2010
7776579Method of degrading hardly degradable protein
Disclosed is an agent for digesting a protein highly resistant to denaturation and degradation, comprising as an active ingredient an enzyme exhibiting an activity of digesting a protein highly resistant to denaturation and degradation and having the following prope...
08/17/2010
7772426Method for producing L-2-amino-4-(hydroxymethylphosphinyl)-butanoic acid
Disclosed is a method for efficiently and highly selectively producing L-2-amino-4-(hydroxymethylphosphinyl)-butanoic acid, which is useful as a herbicide, through a catalytic asymmetric synthesis reaction. Specifically disclosed is a method for producing L-2-amino-...
08/10/2010
76874902-thioethenyl substituted carbapenem derivatives
An objective of the present invention is to provide compounds that are effective against various resistant bacteria which cause current clinical problems, for example, pneumococci including penicillin resistant Streptococcus pneumoneae (PRSP), Haemophilus ...
03/30/2010
7658963Compositions for foods, process for producing the same and functional foods and drinks containing the same
Black currant anthocyanin-containing compositions for foods comprising 1 to 25% by weight of black currant anthocyanin on the basis of solid matters; a process for producing a black currant anthocyanin-containing composition for foods characterized by purifying and ...
02/09/2010
7655266Method for making biscuits
A method for making biscuits wherein a dough mixture is dispensed into an agitator. The dough mixture is agitated as it is being dispensed into cavities of a die. The dough mixture is compressed into the cavities of the die by a compression device. The dough mixture...
02/02/2010
7575892Expression vector encoding a triterpene hydroxylase polypeptide
Soyasapogenol B is biosynthesized via two steps of hydroxylation reaction of its precursor β-amyrin. However, the gene of the hydroxylase concerned in this reaction has not been revealed. Therefore, it was impossible to apply a genetic engineering technique on the ...
08/18/2009
7553989Malonic acid monoesters and process for producing the same
The present invention relates to a compound represented by formula (1) or a salt thereof: wherein R represents a group that is easily removable upon hydrolysis in vivo. This compound is usable in the production of prodrug-t...
06/30/2009
7553640Saponin-decomposing enzyme, gene thereof and large-scale production system for producing soyasapogenol B
The present invention provides a protein having saponin-decomposing activity, more specifically a protein which can decompose a glycoside having soyasapogenol B as an aglycone to produce soyasapogenol B, a polynucleotide encoding such a protein, and a method of prod...
06/30/2009
7547682Tick galectin
A novel galectin, a polynucleotide encoding the same, a vector and a transformant comprising the polynucleotide, an antibody against the galectin, and a screening method for screening a substance capable of modifying the galectin, are disclosed. According to the gal...
06/16/2009
7482439Caprazene as novel compound and derivatives thereof, and caprazol as novel compound and derivatives thereof
Caprazene and caprazol could be synthesized by hydrolysis of a caprazamycin. There could be synthesized a caprazene-1′″-amide derivative of the formula (II) and a caprazene-1′″-ester derivative of the formula (III) ...
01/27/2009
7445922-derived endoglucanase enzyme lacking cellulose-binding domain
This invention relates to a protein that is a Zygomycetes-derived endoglucanase lacking the cellulose-binding domain and exhibits endoglucanase activity, and a method for using the same. This invention can enhance effects of an endoglucanase enzyme on fabric ...
11/04/2008
74393824-alkyl-2-haloaniline derivatives and process for producing the same
The present invention relates to a compound of formula (1), wherein R1, R2, R3, n, and X are as defined in the specification, and a process for producing the same. This compound is useful as an intermediate for the synthesis of compo...
10/21/2008
7432102Transformants producing substance pf1022 derivatives, methods for producing the same, and novel biosynthesis genes
An objective of the present invention is to provide a method for producing substance PF1022 derivatives, in particular PF1022-220 and PF1022-260, by a direct fermentation method, and a transformant to be used for this method. According to the present invention, ther...
10/07/2008
7374921Cellulase tolerant to surfactants
Disclosed is a novel cellulase having an amino acid sequence in which the 162nd and/or 166th amino acid residues in the amino acid sequence of cellulase NCE5 are substituted. Further, a polynucleotide encoding the novel cellulase, an expression vector containing the...
05/20/2008
7365174Azalide and azalactam derivatives and method for producing the same
Compounds represented by the general formula (1) or pharmaceutically acceptable salts thereof, effective in the prevention and/or treatment of infections with microbes: (1) (a) wherein R1 is hydrogen or straight-chain C1-6 alkylcarbonyl; R...
04/29/2008
7351835Organic molecular cataylst having binaphthol skeleton and processes for producing the same and application thereof
A novel organic molecular catalysts represented by the following formula (1) or (2): and a method for carrying out asymmetric reactions/asymmetric synthesis using these organic molecular catalysts. ...
04/01/2008
7335498Saponin-decomposing enzyme, gene thereof and large-scale production system for producing soyasapogenol B
The present invention provides a protein having saponin-decomposing activity, more specifically a protein which can decompose a glycoside having soyasapogenol B as an aglycone to produce soyasapogenol B, a polynucleotide encoding such a protein, and a method of prod...
02/26/2008
7316989Compositions inducing plants disease-resistance and process for producing the same
There is provided a plant disease resistance-inducing composition comprising a filamentous fungus-derived glycosphingolipid. There is also provided a method for controlling a plant disease, comprising the step of treating a target plant with a composition comprising...
01/08/2008
7297357Process for producing puffed snack and production apparatus therefor
A method and apparatus for manufacturing puffed snack having a hard surface layer and soft inside, and having a good texture and a difference in color tone between the surface layer and the inside. After spraying a coating liquid or water onto the surface of a dough...
11/20/2007
7297224Method of deinking waste paper using cellulase without lowering paper strength and method of evaluating the same
A deinking method using a cellulase which enables the load upon the environment to be reduced; and an evaluation method whereby a cellulase effective in deinking and the effective addition level of the cellulase can be appropriately determined. By proposing p...
11/20/2007
7285404Cyclic depsipeptide synthetase and method for recombinant production
The present invention provides an enzyme that synthesizes a cyclic depsipeptide, particularly the substance 1022, and a gene thereof. A cyclic depsipeptide synthetase according to the present invention comprises (a) an amino acid sequence of SEQ ID NO: 2 or (b) a mo...
10/23/2007
7256031Enzyme having β-glucosidase activity and use thereof
The invention is to provide a novel β-glucosidase and a gene that codes for the enzyme, and to develop a technique of utilizing the β-glucosidase or a composition that contains the enzyme for processing plants or plant-derived substances. According to the i...
08/14/2007
7250389Antifungal compound and process for producing the same
Disclosed are novel compounds useful for prevention or control of diseases derived from fungi, a process for producing the same, and novel antifungal agents using the novel compounds. The compounds useful for prevention and treatment of diseases derived from fungi a...
07/31/2007
7238719Process for producing 1,2,3-Triazole compounds
Disclosed is a process for efficiently producing a compound represented by formula (I): wherein R1 represents aryl, amino, alkyl, or alkoxy; R2 represents a protective group of the carboxyli...
07/03/2007
7229985Amorphous substance of tricyclic triazolobenzazepine derivative
Disclosed are 2-(1-isopropoxycarbonyloxy-2-methylpropyl)-7,8-dimethoxy-4(5H), 10-dioxo-2H-1,2,3-triazolo[4,5-c][1]benzazepine, which has been rendered amorphous and possesses improved absorption and dissoluvability, and a pharmaceutical composition com...
06/12/2007
7211413Process for producing purified anthocyanin and crystalline anthocyanin
Provided are a process for producing purified anthocyanidin glucoside in which a rhamnose end of anthocyanidin rutinoside is cleaved using rhamnosidase to convert the anthocyanidin rutinoside component into anthocyanidin glucoside, the anthocyanidin glucoside compon...
05/01/2007
7176163Pharmacological effect potentiators for pesticides
By applying a compound selected from jasmonic acid represented by the following general formula (I) or 2-substituted form of jasmonic acid or derivatives thereof or salts thereof, the pharmacological action of a pesticide such as a microbicide or a herbicide applied...
02/13/2007
7161022Process for producing 4-phenyl-4-oxo-2-butenoic ester derivative
A 4-phenyl-4-oxo-2-butenoate derivative is stably supplied in a short period of time, at low cost, in high purity and on an industrial scale by a process for producing the 4-phenyl-4-oxo-2-butenoate derivative, which comprises simultaneously or continuously reacting...
01/09/2007
7153979Triterpene derivatives and remedies for liver diseases
A triterpene derivative useful for the treatment of hepatic disorders is disclosed. This compound comprises as an active ingredient a triterpene derivative represented by the following formula (I) or a salt thereof:
12/26/2006
7138261Cellulase preparations containing reducing agent and method of processing fiber
A cellulase preparation comprising an endoglucanase derived from Zygomycetes, a cellulose-binding-domain-deleted endoglucanase, or a modified or homologous protein thereof, together with a reducing agent is disclosed. Further, a method of treating cellulose-containi...
11/21/2006
RE39357Medicine for clogging blood vessels of eye fundus
An apparatus for clogging blood vessels of an eye fundus includes an illuminating optical system (1) for illuminating an eye fundus of a subject, who has been given an injection of an infrared fluorescent agent, with infrared rays of light and exciting the in...
10/17/2006
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