Did You Know...
...that power steering was invented by independent inventor Francis W. Davis? As chief engineer in the 1920s of the truck division of the Pierce Arrow Motor Car Company, he saw how hard it was to steer heavy vehicles. So that he would be able to keep the profits from his future invention, Davis left his job, rented a small engineering shop in Waltham, Mass., and developed a hydraulic power steering system that led to power steering.
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| Number | Title | Issue Date |
| 8058227 | Method of treating fibrosis in a subject in need thereof comprising administering a composition comprising a CSD Disclosed are compositions and methods for the treatment of fibrosis. Also disclosed are methods of screening for agents that treat fibrosis. ... | 11/15/2011 |
| 7462480 | Stimulation of microbial dechlorination of polychorinated biphenyls with halogenated ethenes Disclosed is a method for the anaerobic microbial dechlorination of polychlorinated biphenyls (PCBs). Polyhalogenated ethenes are used to stimulate the growth and dechlorinating activity of PCB dechlorinating bacteria in a contaminated soil or sediment. This method ... | 12/09/2008 |
| 6858396 | Positively charged non-natural amino acids, methods of making and using thereof in peptides This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. ... | 02/22/2005 |
| 6783946 | Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine and argini... | 08/31/2004 |
| 6747140 | Tissue kallikrein gene promoter polymorphisms The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence in the subject of a tissue kallikrein promoter allele genotype corre... | 06/08/2004 |
| 6582700 | Linear antigen supporting units The present invention concerns a synthetic construct comprising a linear core chain having two or more side chains pending directly from different points on the linear core chain. Each of the side chains comprises an epitopic site of an antigen or a pepti... | 06/24/2003 |
| 6511800 | Methods of treating nitric oxide and cytokine mediated disorders The current invention discloses novel methods for the inhibition of inducible nitric oxide synthesis (iNOS) and the production of NO. Methods of inhibiting the induction of proinflammatory cytokines are also described. Methods of treating various disease ... | 01/28/2003 |
| 6376182 | Methods and compositions for correlating tissue kallikrein gene promoter polymorphisms with treatment of essential hypertension The present invention provides a method of identifying a human subject as having an increased likelihood of regulating blood pressure with dietary sodium intake, comprising determining the presence in the subject of a tissue kallikrein promoter allele gen... | 04/23/2002 |
| 6358922 | Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine... | 03/19/2002 |
| 6103528 | Reversible gelling culture media for in-vitro cell culture in three-dimensional matrices A gelling cell culture medium useful for forming a three dimensional matrix for cell culture in vitro is prepared by copolymerizing an acrylamide derivative with a hydrophilic comonomer to form a reversible (preferably thermally reversible) gelling linear... | 08/15/2000 |
| 6057095 | Screening procedure for inhibitors of HIV Rev function This invention provides a method of screening for inhibitors of HIV Rev function, comprising introducing into a cell a nucleic acid construct comprising a reporter gene positioned in the construct such that expression of the reporter gene increases when R... | 05/02/2000 |
| 6043218 | Positively charged non-natural amino acids, methods of making thereof, and use thereof in peptides This invention relates to positively charged non-natural amino acids, methods of making thereof, and utilization thereof in peptides. In one embodiment, the invention relates to non-natural amino acids that closely replicate the natural amino acids lysine... | 03/28/2000 |
| 5916869 | Method of treating birds in ovo Methods are disclosed for administering Peptide YY (PYY) receptor agonists to birds in ovo to promote altricial development of the intestinal tract of neonatal birds. Enhanced altricial development of the small intestine in hatchling birds results in an i... | 06/29/1999 |
| 5891456 | Glyceryl monosterate based biodegradable implants for site-specific delivery of drugs A method to administer a drug locally to a subject in which biodegradable dosage forms that contain the drug are implanted at a localized site beneath the skin of the subject whereupon the dosage forms release the drug over a desired period of time at a s... | 04/06/1999 |
| 5877215 | Method of treating neoplastic cells with prostaglandin and radiation treatment or prostaglandin and platinum-based anti-tumor agents The invention is directed to a method of increasing ionizing radiation's cytotoxic effects on a neoplasm in a subject by increasing the neoplasm's sensitivity to ionizing radiation, comprising administering a therapeutically effective amount of prostaglan... | 03/02/1999 |
| 5824519 | Tissue-specific and target RNA-specific ribozymes The invention provides tissue-specific and target RNA-specific ribozymes. These ribozymes can be used to destroy target-specific neoplasms and to treat viral infections, among other uses. The ribozymes of the present invention comprise a 5' autocatalytica... | 10/20/1998 |
| 5811395 | Relaxin analogs and derivatives methods and uses thereof The present invention relates to a relaxin analogs and derivatives, and uses thereof. The present invention further relates to compositions comprising a relaxin analogs and derivatives, and relaxin wherein such composition exhibits an additive or synergis... | 09/22/1998 |
| 5764339 | Compressive force-activated variable focus lens and method of making the same A variable focus contact lens, has a body with a first half and an opposite second half. The body also has a first peripheral surface, an opposite second peripheral surface and an associated focal length. The lens includes a first material having a resili... | 06/09/1998 |
| 5645558 | Anatomically shaped vasoocclusive device and method of making the same This invention is an occlusive device for inserting into body cavities or vesicles. More particularly, it is a vasoocclusive device which, as used, is in the approximate shape of an anatomical cavity. It may be ultimately deployed as a substantially spher... | 07/08/1997 |
| 5525347 | Composition and methods for treating performance anxiety The invention provides a pharmaceutical composition for treating performance anxiety and social phobia comprising a therapeutic amount for the treatment of a patient of a ଲ-adrenergic receptor blocking compound and an anti-diaphoretic compound. The ... | 06/11/1996 |
| 5458601 | Adjustable ligament anchor The invention provides an adjustable ligament anchor for attaching a ligament to a bone. The ligament anchor comprises a housing having an exterior surface, an interior surface, an intra-articular end and an opposite extra-articular end. The interior surf... | 10/17/1995 |
| 5428660 | Portable medical panoramic radiographic device A portable, lightweight medical radiographic device having an articulated support is described. The device includes a base, an elongated supporting structure having multiple sections interconnected by adjustable joints, a mount for a radiological camera, ... | 06/27/1995 |
| 5334369 | Platelet receptor antagonists useful in detecting intravascular platelet aggregation This invention provides novel compounds used in a method of determining platelet deposition. These compounds include 123 I-SAP and analogues. Also provided is a method of determining platelet deposition in a subject comprising binding an effect... | 08/02/1994 |
| 4610878 | Use of in vitro assay techniques to measure parameters related to clinical applications of transfer factor therapy Described herein are methods for quantifying in vitro various parameters related to the use of transfer factor (e.g., dialyzable leukocyte extract containing transfer factor) in the therapeutic and/or prophylactic treatment of patients having antigen-sele... | 09/09/1986 |
