Did You Know...
...that the Eveready Battery began as an invention called the "electric flowerpot," which was a tube with a battery and light bulb inside? The idea was to fasten this gizmo to the side of a flowerpot so it would illuminate the flowers from the bottom. The idea died on the vine and the businessman who licensed the flower pot, Conrad Huber, was left with a pile of useless tubes -- until he found a way to market them as batteries to light the world!
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| Number | Title | Issue Date |
| 8165661 | Method and apparatus for analyzing amniotic fluid Methods and spectra for monitoring fetal growth and predicting birth weight of an infant prior to birth are provided wherein one or more selected biological markers are measured in a sample of amniotic fluid obtained from a pregnant woman. Levels of the selected bio... | 04/24/2012 |
| 8143005 | Nucleic acids encoding sodium channel SCN1A alpha subunit proteins and mutations associated with epilepsy The present invention relates to epilepsy. More particularly, the present invention relates to idiopathic generalized epilepsy (IGE) and to the identification of three genes mapping to chromosome 2, which show mutations in patients with epilepsy. The invention furth... | 03/27/2012 |
| 8043825 | Serum biomarkers for Chagas disease The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying Chagas disease status in a patient. In particular, the biomarkers of this invention are useful to classify a subject sample as infected with Chagas disea... | 10/25/2011 |
| 8024691 | Automata unit, a tool for designing checker circuitry and a method of manufacturing hardware circuitry incorporating checker circuitry The present invention relates to an automata unit, a tool for designing circuitry and/or checker circuitry, and a method for manufacturing hardware circuitry. The automata unit includes an input unit for receiving assertions using Boolean expressions, an automata ge... | 09/20/2011 |
| 7981399 | Method to determine state of a cell exchanging metabolites with a fluid medium by analyzing the metabolites in the fluid medium The present invention relates to a method for determining the ideal time for and outcome of reproductive health procedures including in vitro fertilization by establishing a correlation between the successful outcome of said procedure and the spectra of a body fluid... | 07/19/2011 |
| 7951931 | Nucleic acid encoding sodium channel SCN3A alpha subunits The present invention relates to epilepsy. More particularly, the present invention relates to idiopathic generalized epilepsy (IGE) and to the identification of three genes mapping to chromosome 2, which show mutations in patients with epilepsy. The invention furth... | 05/31/2011 |
| 7691092 | Ambulatory device for measuring urine flow An ambulatory device for measuring urine flow comprises a portable hand-held container and a handgrip mounted thereto. A flow-measuring device is located in the container, and a means for collecting the data measured by the flow-measuring device is also provided. Th... | 04/06/2010 |
| 7677079 | Method and device for sensing wear A sensor for detecting erosion of a wear surface of a component, particularly a liner attached to the mill shell of a rotating grinding mill. The sensor comprises a conductive element embedded in the component, the conductive element comprising a first end positione... | 03/16/2010 |
| 7662768 | Transdifferentiation of pancreatic acinar cells Pancreatic acinar cells contribute to β-cell neogenesis. Hamsters administered pentadecapeptide of INGAP protein demonstrated a 2-fold increase in the number of extra-islet acinar-associated β-cell clusters resulting in a 2.8-fold increase in the overall extra-isl... | 02/16/2010 |
| 7637980 | Method of increasing photosynthesis in plants comprising an exposure thereof to lipochitooligosaccharides and compositions therefor The present invention relates to agriculture. More particularly, the invention relates to a method of increasing photosynthesis of a plant and more particularly of crop plants. In addition, the invention relates to a method of increasing photosynthesis and/or yield ... | 12/29/2009 |
| 7626005 | Inhibitors of aminoglycoside 6′--acetyltransferases, compositions and uses thereof The present invention relates to novel inhibitors of aminoglycoside 6′-N-acetyltransferases, more specifically, AAC(6′)-li and AAC(6′)-ly, as well as compositions and uses thereof. Furthermore, the present invention relates to synthetic methodologies for prepa... | 12/01/2009 |
| 7608839 | Plasma source and applications thereof A low-power atmospheric pressure plasma source, comprising a plasma-forming region for injection of a plasma-forming gas; an excitation region for injection of a source of reactive species downstream of the plasma-forming region; and a narrow converging plasma exit ... | 10/27/2009 |
| 7440654 | Wavelength multiplexer/demultiplexer comprising an optically dispersive stratified body The present invention provides a wavelength multiplexer/demultiplexer comprising a plurality of regions of optically permissive material. The plurality of regions are disposed adjacent one another in a side by side relationship in order to define a stratified body. ... | 10/21/2008 |
| 7427220 | Amphibious robotic device A control system for a robotic device maneuverable in at least a liquid medium, the system having at least one visual sensor retrieving an image of the device's environment, an image analyzing module receiving the image, determining a presence of an object of a give... | 09/23/2008 |
| 7393837 | Inhibition of PEX in the treatment of metabolic bone diseases The present invention relates to a method of treating metabolic bone diseases in a patient, which comprises the modulation of PEX activity to modulate the bone micro-environmental concentrations of critical bone anabolic agents, namely PTH and PTHrP. The present inv... | 07/01/2008 |
| 7364852 | Short GCG expansions in the PAB II gene for oculopharyngeal muscular dystrophy and diagnostic thereof The present invention relates to a human PAB II gene containing transcribed polymorphic GCG repeat, which comprises a sequence as set forth in SEQ ID NO:3, which includes introns and flanking genomic sequence. The allelic variants of GCG repeat of the human PAB II g... | 04/29/2008 |
| 7186520 | Substrate for assaying ribonuclease H activity The invention relates to a substrate and method for the assay of ribonuclease H activity. The substrate comprises a DNA/RNA heteroduplex molecule having fluorophore and quencher molecules in close proximity, which emit a background level of fluorescence in the absen... | 03/06/2007 |
| 7173002 | 150 KDA TGF-B1 accessory receptor acts a negative modulator of TGF-B signaling The present invention relates to a TGF-β1 binding protein called r150. This protein has a GPI-anchor contained in r150 itself and not on a tightly associated protein and that it binds TGF-β1 with an affinity comparable to those of the signaling receptors. Furtherm... | 02/06/2007 |
| 7169411 | Composition for delivery of biological agents and methods for the preparation thereof A composition for facilitating delivery of biological agents, comprising a therapeutic or diagnostic agent and a supramolecular complex, the latter comprising (i) a block copolymer, having at least one nonionic, water soluble segment and at least one polyionic segme... | 01/30/2007 |
| 7138369 | Compounds and methods for modulating apoptosis Cyclic peptides and compositions comprising such cyclic peptides are provided. The cyclic peptides comprise a classical cadherin cell adhesion recognition sequence HAV. Methods for using such peptides and compositions for inducing apoptosis in cadherin-expressing ce... | 11/21/2006 |
| 7132274 | Method for identifying modulators of CLK-1 and UbiF activity The present invention provides methods for screening modulators of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinone (DMQ) hydroxylation activity, inhibitors and activators of the activity, and methods of using such compounds. More particularly, this invention relate... | 11/07/2006 |
| 7127962 | Four-degree-of-freedom parallel manipulator for producing Schönflies motions The present invention relates to a manipulating device (A) for producing Schönflies motions comprising a parallel array of at least two legs (B), each leg (B) including an actuator unit (C) having first and second ends and producing a pan-tilt motion, each leg (B) ... | 10/31/2006 |
| 7129341 | Identification of essential fungal specific genes and use thereof in antifungal drug discovery The invention relates to the identification and disruption of essential fungal specific genes isolated in the yeast pathogen Candida albicans namely CaKRE5, CaALR1, and CaCDC24 and to the use thereof in antifungal diagnosis and as essential antifungal targets... | 10/31/2006 |
| 7122155 | Electron microscopy cell fraction sample preparation robot A parallel processing, fluid handling apparatus for concurrent temperature controlled preparation of a plurality of cell fraction samples adapted to be used for electron microscopic viewing. The apparatus comprises generally a sample receiving member, a fluid handli... | 10/17/2006 |
| 7115227 | Heat pipe A heat pipe assembly (10/110), under vacuum and having a working substance charged therein, comprising generally an evaporator (12/112) adapted to evaporate the working fluid and a condenser (16/116). The heat exchanging condenser is in fluid fl... | 10/03/2006 |
| 7098012 | DNA demethylase, therapeutic and diagnostic uses thereof The present invention relates to a DNA demethylase enzyme having about 40 KDa, and wherein said DNA demethylase enzyme is overexpressed in cancer cells and not in normal cells. The present invention also relates to the therapeutic and diagnostic uses of the DNA deme... | 08/29/2006 |
| 7071375 | Nuclear fertility restorer genes and methods of use in plants The present invention includes nuclear fertility restorer genes, proteins encoded by those genes and transgenic plants and plant cells containing those genes. More particularly, the nuclear fertility restorer genes can be used to restore fertility in cytoplasmic mal... | 07/04/2006 |
| 7063842 | Compounds and methods for inhibiting the interaction between α-catenin and β-catenin Modulating agents for inhibiting an interaction between α-catenin and β-catenin are provided. The modulating agents comprise one or more of: (a) a β-catenin HAV motif; (b) a peptide analogue or mimetic of a β-catenin HAV motif; or (c) an antibody or antigen-bind... | 06/20/2006 |
| 7045612 | Human methionine synthase reductase: cloning, and methods for evaluating risk of neural tube defects, cardiovascular disease, and cancer The invention features a novel gene encoding methionine synthase reductase. The invention also features a method for detecting an increased likelihood of hyperhomocysteinemia and, in turn, an increased or decreased likelihood of neural tube defects, cardiovascular d... | 05/16/2006 |
| 7035269 | Method and apparatus for distributed synchronous clocking A method and an apparatus are provided for synchronizing clock signals in spatially distributed nodes in large, synchronous electronic, optical, optoelectronic or wireless systems, such as systems comprising arrays of microprocessors and memories, and telecommunicat... | 04/25/2006 |
| 6971276 | Recovery of purified volatile metal such as lithium from mixed metal vapors The present invention is concerned with a method for extracting selectively a metal from a metal mixture in the gaseous phase. The method comprises heating the metal mixture to vaporize the metal; condensing the metal contaminants present in the vapor; reacting any ... | 12/06/2005 |
| 6969608 | Pharmaceuticals containing multipotential precursor cells from tissues containing sensory receptors Current sources of neural stem and progenitor cells for neural transplantation are essentially inaccessible in living animals. This invention relates to neural precursor cells (stem cells, progenitor cells or a combination of both types of cells) isolated from the o... | 11/29/2005 |
| 6967238 | Compounds and methods for modulating cell adhesion Cyclic peptides comprising a cadherin cell adhesion recognition sequence HAV, and compositions comprising such cyclic peptides, are provided. Methods for using such peptides for modulating cadherin-mediated cell adhesion in a variety of contexts are also provided. | 11/22/2005 |
| 6951970 | Method for enhancement of naturally occurring cytoplasmic male sterility and for restoration of male sterility and for restoration of male fertility and uses thereof in hybrid crop production The present invention relates to methods for enhancement of naturally occurring cytoplastic male sterility and for restoration of male fertility and uses thereof in hybrid crop production. There is also disclosed a method for restoration of male fertility to cytopla... | 10/04/2005 |
| 6949378 | C. elegans gro-1 gene The invention relates to the identification of gro-1 gene and to demonstrate that the gro-1 gene is involved in the control of a central physiological clock. Also disclosed are four other genes located within the same operon as the gro-1 gene. ... | 09/27/2005 |
| 6931579 | Integrated excitation/extraction system for test and measurement An integrated test core for mixed-signal circuits comprises a periodic waveform generator capable of generating arbitrary band-limited waveforms for excitation purposes and a waveform digitizer for extracting an arbitrary waveform from the test circuit's analog resp... | 08/16/2005 |
| 6917320 | Method and device for use in DC parametric tests A system and device suitable for use in performing a DC parametric test on an external load is provided. The device may be configured to apply a desired voltage or current to the external load. The circuit device receives a forcing parameter signal at an input and r... | 07/12/2005 |
| 6914044 | Compounds and methods for modulating cell adhesion Cyclic peptides and compositions comprising such cyclic peptides are provided. The cyclic peptides comprise a cadherin cell adhesion recognition sequence HAV. Methods for using such peptides and compositions for modulating cadherin-mediated cell adhesion in a variet... | 07/05/2005 |
| 6914548 | Programmable DC voltage generator An efficient technique for generating accurate on-chip DC reference voltages is based on filtering a digital pulse modulated sequence in order to extract its average value encoding a DC level, A passive on-chip filter is used for simplicity with an all-digital modul... | 07/05/2005 |
| 6861518 | Preparation of phosphorothioate oligomers Methods and Intermediates for the Preparation of Oligomers Containing Diastereomerically Enriched Phosphorothioate Linkages are Disclosed. ... | 03/01/2005 |
