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Assignee: Massachusetts Institute of Technology


Location: Cambridge, MA
No. of patents: 590

1                      
NumberTitleIssue Date
8185551Disk-resident streaming dictionary
A method, apparatus and computer program product for storing data in a disk storage system is presented. A dictionary data structure is defined and stored on the disk storage system. Key-value pairs can be inserted and deleted into the dictionary data structure, wit...
05/22/2012
8182804Engineered enzymatically active bacteriophages and methods of uses thereof
The present invention provides engineered bacteriophages that express at least one biofilm degrading enzyme on their surface and uses thereof for degrading bacterial biofilms. The invention also provides genetically engineered bacteriophages expressing the biofilm d...
05/22/2012
8182464Method for intravesical drug delivery
Implant devices for intravesical administration and local drug delivery. The device has a body which includes a hollow tube formed of a biocompatible material; at least one reservoir in the tube which contains a drug; and one or more apertures through which the drug...
05/22/2012
8174181Quantum dot white and colored light-emitting devices
A light-emitting device comprising a population of quantum dots (QDs) embedded in a host matrix and a primary light source which causes the QDs to emit secondary light and a method of making such a device. The size distribution of the QDs is chosen to allow light of...
05/08/2012
8173384Methods for analyzing or processing a heparin sample
The invention relates to methods and products for analyzing or processing a heparin sample. In one embodiment, the methods comprise contacting the sample with heparinase I, heparinase II and heparinase III, determining the amount of a signature component in the samp...
05/08/2012
8173010Method of dry reforming a reactant gas with intermetallic catalyst
The invention relates to materials used as electrodes and/or catalysts, as well as methods associated with the same. The materials may comprise an alloy or intermetallic compound of a transition metal (e.g., Ni) and a metal additive (e.g., Sn). The transition metal ...
05/08/2012
8172790Needle-free injector device with autoloading capability
A needle-free transdermal transport device includes a chamber (900) for holding the substance to be injected, a nozzle (910) in fluid communication with the chamber, and a drug reservoir (950) for storing the substance to be transferred to the c...
05/08/2012
8172784Compositions, methods, and devices for treating liver disease
Described are compositions and methods for treating liver disease, e.g., acute liver disease, using bone marrow-derived stem cells and bone marrow-derived stem cell conditioned media. ...
05/08/2012
8171915Fuel management system for variable ethanol octane enhancement of gasoline engines
Fuel management system for efficient operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder of the engine. A fuel management microprocessor system controls injection of the anti-knock agent so as ...
05/08/2012
8168879Solar thermoelectric conversion
Systems and methods utilizing solar-electrical generators are discussed. Solar-electrical generators are disclosed having a radiation-capture structure and one or more thermoelectric converters. Heat produced in a capture structure via impingement of solar radiation...
05/01/2012
8168326Battery structures, self-organizing structures and related methods
An energy storage device includes a first electrode comprising a first material and a second electrode comprising a second material, at least a portion of the first and second materials forming an interpenetrating network when dispersed in an electrolyte, the electr...
05/01/2012
8164384Asymmetric multilevel outphasing architecture for RF amplifiers
A radio frequency (RF) circuit includes a power supply configured to generate a plurality of voltages, a plurality of power amplifiers, each having an RF output port and a power supply input port, a switch network having a plurality of input ports coupled to the pow...
04/24/2012
8163374Formation of close-packed sphere arrays in V-shaped grooves
The present invention relates to the self-assembly of a spherical-morphology block copolymer into V-shaped grooves of a substrate. Although spherical morphology block copolymers typically form a body-centered cubic system (bcc) sphere array in bulk, the V-shaped gro...
04/24/2012
8160404High speed and low loss GeSi/Si electro-absorption light modulator and method of fabrication using selective growth
An optoelectronic device includes an input waveguide structure that receives an input optical signal. A GeSi/Si waveguide structure receives from the input waveguide the input optical signal and performs selective optoelectronic operations on the input optical signa...
04/17/2012
8159680Single-transducer, three-dimensional laser imaging system and method
Disclosed herein are a system and method for three-dimensional imaging using a single transducer. A laser in a transmitter emits a sequence of short pulses, each of which is at a different center wavelength (frequency). A dispersive element in the transmitter spatia...
04/17/2012
8158437Luminescent detection of hydrazine and hydrazine derivatives
The present invention generally relates to methods for modulating the optical properties of a luminescent polymer via interaction with a species (e.g., an analyte). In some cases, the present invention provides methods for determination of an analyte by monitoring a...
04/17/2012
8158338Resist sensitizer
Methods and compositions for enhancing the sensitivity of a resist composition are disclosed. In one aspect, compositions for use with a matrix material (e.g., a lithographically sensitive polymeric material) can be formulated with an acid generator and a sensitizer...
04/17/2012
8158193Highly luminescent color-selective nanocrystalline materials
A nanocrystal capable of light emission includes a nanoparticle having photoluminescence having quantum yields of greater than 30%. ...
04/17/2012
8155113Processing data in a parallel processing environment
An integrated circuit includes a plurality of tiles, and a plurality of interface modules coupled to the switches of a subset of the tiles. Each tile comprises a processor, and a switch including switching circuitry to forward data over data paths from other tiles t...
04/10/2012
8154729Near field detector for integrated surface plasmon resonance biosensor applications
A near-field surface plasmon detector is provided. The near-field surface plasmon detector includes one or more semiconductor layers that absorb one or more surface plasmons of thin metal films in the vicinity of the semiconductor layer. The surface plasmons are exc...
04/10/2012
8154063Ultrafast and ultrasensitive novel photodetectors
A photodetector is provided that includes a FET structure with a channel structure having one or more nanowire structures. Noble metal nanoparticles are positioned on the channel structure so as to produce a functionalized channel structure. The functionalized chann...
04/10/2012
8153233Patterned coatings having extreme wetting properties and methods of making
A surface with superhydrophobic and hydrophilic or superhydrophilic regions can be made. The hydrophilic or superhydrophilic regions can selective collect water on the surface. ...
04/10/2012
8153119Engineered enzymatically active bacteriophage and methods for dispersing biofilms
The present invention is directed to engineered enzymatically active bacteriophages that are both capable of killing the bacteria by lysis and dispersing the bacterial biofilm because they have been also engineered to express biofilm-degrading enzymes, particularly ...
04/10/2012
8149265Holographic video display system
A holographic video display comprises a monochromatic light source, a video signal generator, guided-wave acousto-optic modulators for diffracting light according to signals received from the video signal generator, a vertical scanning subsystem, and an optical path...
04/03/2012
8148985Method for reducing maximum local specific absorption rate in magnetic resonance imaging
A method for reducing maximum local specific absorption rate (“SAR”) in a magnetic resonance imaging (“MRI”) system is disclosed. More specifically, a plurality of candidate radio frequency (“RF”) pulses are designed and the manner in which they are appl...
04/03/2012
8148159System and methods for stretching polynucleotides
Apparatus and methods are described for achieving uniform stretching of polynucleotides in hybrid electrophoretic-gel, micro-constricting microfluidic channels. Polynucleotides in normally relaxed configurations are driven by an electric field along a microfluidic c...
04/03/2012
8148013Conductive lithium storage electrode
A compound comprising a composition Ax(M′1-aM″a)y(XD4)z, Ax(M′1-aM″a)y(DXD4)z, or Ax(M′1-aM″a
04/03/2012
8148009Reticulated and controlled porosity battery structures
The effective ionic conductivity in a composite structure is believed to decrease rapidly with volume fraction. A system, such as a bipolar device or energy storage device, has structures or components in which the diffusion length or path that electrodes or ions mu...
04/03/2012
8148001Devices for storing energy in the mechanical deformation of nanotube molecules and recovering the energy from mechanically deformed nanotube molecules
An energy storage device includes at least one nanotube. An energy storage mechanism converts energy external to the device into the appropriate levels of strain on the at least one nanotube to produce stored energy, and an energy recovery mechanism converts the ene...
04/03/2012
8147914Orientation-controlled self-assembled nanolithography using a block copolymer
Disclosed is a structure made of a trench patterned substrate having a pre-determined trench period and a pre-determined mesa to trench width ratio, and a block copolymer on top of the trench patterned substrate. The block copolymer has at least an organic block and...
04/03/2012
8146568Fuel management system for variable ethanol octane enhancement of gasoline engines
Fuel management system for efficient operation of a spark ignition gasoline engine. Injectors inject an anti-knock agent such as ethanol directly into a cylinder of the engine. A fuel management microprocessor system controls injection of the anti-knock agent so as ...
04/03/2012
8145457Method and apparatus for modeling deformation of a deformable body embossed with a stamp
Hot embossing may be more advantageous than other polymer microfabrication processes. An example embodiment of the present invention relates to a method and corresponding apparatus for developing a computationally inexpensive viscoelastic model for the hot embossing...
03/27/2012
8143601Nanoscale imaging via absorption modulation
An imaging system is provided. The imaging system includes a sample to be scanned by the imaging system. An absorbance modulation layer (AML) is positioned in close proximity to the sample and is physically separate from the sample. One or more sub-wavelength apertu...
03/27/2012
8143368Disposable medical supplies from hydrolytically biodegradable plastics
Hydrolytically degradable polymers in the form of biodegradable disposable medical devices for use in medicine and laboratories such as syringes, test tubes, catheters, tubing, trays, medical fabrics, and gloves are described. The devices are formed in whole or in p...
03/27/2012
8143234Uridine administration improves phosphatide synthesis, synaptic transmission and cognitive function
The present invention provides methods of improving a cognitive function or a neurological function, treating or ameliorating a decline in a cognitive function or a neurological function, increasing cytidine levels, or treating a neurological disorder in a subject, ...
03/27/2012
8143042Biodegradable elastomers
The present inventions in various aspects provide elastic biodegradable polymers. In various embodiments, the polymers are formed by the reaction of a multifunctional alcohol or ether and a difunctional or higher order acid to form a pre-polymer, which is cross-link...
03/27/2012
8140143Washable wearable biosensor
A washable, wearable biosensor that can gather sensor data, communicate the sensed data by wireless protocols, and permits the analysis of sensed data in real-time as a person goes about their normal lifestyle activities. The biosensor can be worn in multiple positi...
03/20/2012
8138843Gated ring oscillator for a time-to-digital converter with shaped quantization noise
Described is a compact, lower power gated ring oscillator time-to-digital converter that achieves first order noise shaping of quantization noise using a digital implementation. The gated ring oscillator time-to-digital converter includes a plurality of delay stages...
03/20/2012
8137925Methods and compositions for protein labeling using lipoic acid ligases
The invention provides compositions and methods of use thereof for labeling peptide and proteins in vitro or in vivo. The methods described herein employ lipoic acid ligase or mutants thereof, and lipoic acid analogs recognized by lipoic acid ligase and lipoic acid ...
03/20/2012
8135128Animatronic creatures that act as intermediaries between human users and a telephone system
An animatronic telephone agent consisting of a communications subsystem connected to a wired or wireless telephone network for receiving incoming telephone calls, and a robotic automaton coupled to the communications subsystem and responsive to incoming telephone ca...
03/13/2012
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