...Chester Carlson was a patent agent who tired of having to make multiple copies of patent applications using the only duplication method available at the time: carbon paper. In 1959 he came up with a new copying system and took it to IBM for evaluation. The "experts" at IBM determined potential sales to be only 5,000 units because people wouldn't want to use a bulky machine when they had carbon paper. Carlson's invention was the xerography process, the company founded on the system is Xerox.
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| Number | Title | Issue Date |
| 8442892 | REIT-based pure property return indexes The present disclosure is directed to generating REIT-based pure property return indexes. First, REIT return data is compiled from each REIT of a plurality of REITs at a predetermined frequency. Then, the generated REIT return data is de-levered and processed accord... | 05/14/2013 |
| 8442078 | Microfluidic radial fiber laser utilizing an external polarizer to modulate its azimuthal intensity distribution The laser includes an optical fiber including a cavity containing a microfluidic gain medium bounded by a composite structure of alternating layers of high and low index materials forming an axially invariant, rotationally symmetric photonic bandgap cavity. The opti... | 05/14/2013 |
| 8440835 | Environmentally sensitive fluorophores The present invention generally relates to environment-sensitive fluorophores, including environment-sensitive fluorophores for reporting protein/protein and peptide/protein interactions. In one aspect, the present invention is directed to compounds and salts thereo... | 05/14/2013 |
| 8440610 | Mapkap kinase-2 as a specific target for blocking proliferation of P53-defective cells The present invention relates to compounds and pharmaceutical compositions for treating cellular proliferative disorders, e.g., in patients having one or more p53-deficient cells, screening assays for identifying such compounds, and methods for treating such disorde... | 05/14/2013 |
| 8440063 | Electrokinetic concentration devices The present invention provides a device and methods of use thereof in concentrating a species of interest and/or controlling liquid flow in a device. The methods make use of a device comprising a fluidic chip comprising a planar array of channels through which a liq... | 05/14/2013 |
| 8437890 | Integrated framework for vehicle operator assistance based on a trajectory prediction and threat assessment Various types and levels of operator assistance are performed within a unified, configurable framework. A model of the device with a model of the environment and the current state of the device and the environment are used to iteratively generate a sequence of optim... | 05/07/2013 |
| 8437819 | Superconductor cable Superconductor cable having a plurality of flat, tape-shaped ribbon superconductor wires assembled to form a stack having a rectangular cross section, the stack having a twist about a longitudinal axis of the stack. Multiple superconductor cables including twisted s... | 05/07/2013 |
| 8436336 | Structure and method for a high-speed semiconductor device having a Ge channel layer The invention provides semiconductor structure comprising a strained Ge channel layer, and a gate dielectric disposed over the strained Ge channel layer. In one aspect of the invention, a strained Ge channel MOSFET is provided. The strained Ge channel MOSFET include... | 05/07/2013 |
| 8436116 | Responsive materials for isolating organic compounds One aspect of the present invention relates to polymers containing redox-responsive moieties (such as, ferrocene). In certain embodiments, the present invention relates to in-situ continuous separation systems which use such redox-responsive polymers for low-molecul... | 05/07/2013 |
| 8435961 | Methods and compositions for increasing the activity of inhibitory RNA The invention provides methods for increasing the activity of an inhibitory RNA (RNAi) in a subject requiring administering one or more poly-ADP-ribose polymerase (PARP) inhibitors and/or one or more PARG activators to the subject. The invention also provides method... | 05/07/2013 |
| 8435387 | Small-scale method and apparatus for separating mixtures The present invention generally relates to the small-scale separation of a mixture of two or more components with different boiling points into enriched fractions. In some embodiments, a first and second fluid (e.g., a liquid and a gas, a liquid and a liquid, etc.) ... | 05/07/2013 |
| 8433158 | Optical superresolution using multiple images An imaging system is provided. The imaging system includes a point spread function (PSF) module producing a diffraction-limited image of a sample. A convolution module performs convolution of the diffraction-limited image with a first image of a focal spot having a ... | 04/30/2013 |
| 8432553 | Phase from defocused color images Phase differences associated with a defocused wavefront can be determined from a single color image. The color image, which is a measurement of intensity as a function of wavelength, is used to calculate the change in intensity with respect to wavelength over the im... | 04/30/2013 |
| 8432239 | Micro-electro mechanical tunneling switch A micro-electromechanical system switch includes a substrate and a plurality of actuating electrodes formed the substrate wherein each actuating electrode is activatable. A cantilever beam has a first end and a second end and a plurality of stops formed thereon. The... | 04/30/2013 |
| 8431506 | Biotemplated inorganic materials A method of making a metal oxide nanoparticle comprising contacting an aqueous solution of a metal salt with an oxidant. The method is safe, environmentally benign, and uses readily available precursors. The size of the nanoparticles, which can be as small as 1 nm o... | 04/30/2013 |
| 8428897 | Method and apparatus for spectral cross coherence The present invention relates to a machine implemented method for spectral analysis that determines a measure of cross coherence between application of two spectral estimation filters to data; and identifies a spectral feature of the measure of cross coherence. One ... | 04/23/2013 |
| 8427630 | Semiconductor manufacturing apparatus Disclosed herein is a semiconductor manufacturing apparatus. The semiconductor manufacturing apparatus precisely adjusts the position and size of a light spot formed on a substrate, enabling formation of a target pattern or elimination of an unnecessary pattern in a... | 04/23/2013 |
| 8426797 | CMOS readout architecture and method for photon-counting arrays Embodiments of the present invention include complementary metal-oxide-semiconductor (CMOS) readout architectures for photon-counting arrays with a photon-counting detector, a digital counter, and an overflow bit in each of the sensing elements in the array. Typical... | 04/23/2013 |
| 8426208 | Method and apparatus for determining radiation The present invention relates to devices, systems, and methods for determination of ionizing radiation. In some embodiments, the devices comprise nanocomposite materials containing nanostructures (e.g., carbon nanotubes) dispersed in radiation sensitive polymers. In... | 04/23/2013 |
| 8420391 | RNA sequence-specific mediators of RNA interference The present invention relates to a Drosophila in vitro system which was used to demonstrate that dsRNA is processed to RNA segments 21-23 nucleotides (nt) in length. Furthermore, when these 21-23 nt fragments are purified and added back to Drosophila extracts, they ... | 04/16/2013 |
| 8419764 | Surgical puncture access A surgical device mitigates over-puncture with a bias spring that biases a leading, cutting edge in the opposite direction of the anticipated over-puncture. An associated locking mechanism is configured to release the force of the bias spring in a direction counter ... | 04/16/2013 |
| 8418535 | Method and apparatus for integrated measurement of the mass and surface charge of discrete microparticles using a suspended microchannel resonator Measurements of the mass and surface charge of microparticles are employed in the characterization of many types of colloidal dispersions. The suspended microchannel resonator (SMR) is capable of measuring individual particle masses with femtogram resolution. The hi... | 04/16/2013 |
| 8415755 | Wheatstone-bridge magnetoresistive device A magnetoresistive Wheatstone-bridge structure includes a magnetoresistive ring structure. The magnetoresistive ring structure includes a first magnetic layer comprising a ferromagnetic material. A second magnetic layer also includes a ferromagnetic material. A non-... | 04/09/2013 |
| 8414912 | Contact lens drug delivery device The present invention relates generally to devices and methods for administering one or more active agents to the eye of a human or animal patient in need thereof, and more particularly to devices for application to the cornea which release active agent to the eye i... | 04/09/2013 |
| 8411140 | Tactile sensor using elastomeric imaging A tactile sensor includes a photosensing structure, a volume of elastomer capable of transmitting an image, and a reflective skin covering the volume of elastomer. The reflective skin is illuminated through the volume of elastomer by one or more light sources, and h... | 04/02/2013 |
| 8410843 | Polyphase nonlinear digital predistortion Polyphase nonlinear digital predistorters (pNDPs) mitigate nonlinear distortions generated by time-interleaved digital-to-analog converters (TIDACs). Processors in an example pNDP compute nonlinear and linear compensation terms representative of channel mismatches a... | 04/02/2013 |
| 8410798 | Flexural mechanism for passive angle alignment and locking A passive alignment structure is provided that includes at least one rigid post being coupled to a top surface and a bottom surface. At least one in-plane clamp is associated with a respective at least one rigid post. The at least one in-plane clamp receives a clamp... | 04/02/2013 |
| 8409820 | Kinase sensors The present invention generally relates to compositions and methods for determining kinase activity. In some cases, the compositions comprise a triazole heterocycle. In some embodiments, the compositions comprise a quinoline moiety. In one aspect, the present invent... | 04/02/2013 |
| 8406889 | Conducting polymer nanowire brain-machine interface systems and methods The present invention relates to conducting polymer nanowires and their use in a brain-machine interface which is secure, robust and minimally invasive. In accordance with a first aspect of the present invention, a vascular-based brain-machine interface comprising c... | 03/26/2013 |
| 8406267 | Grazing-incidence-disk laser element A solid-state gain element including a thin doped region in which an optical signal propagates through the thin doped region at a large angle with respect to the normal to the thin doped region, reflects at a boundary of the thin doped region, and passes through the... | 03/26/2013 |
| 8405834 | Methods and apparatus for optical coherence tomography scanning In one aspect, the invention relates to a method of acquiring optical coherence tomographic data from a sample. The method includes the steps of scanning a first location on the sample to obtain a first set of optical coherence tomographic data, scanning a second lo... | 03/26/2013 |
| 8405742 | Processing images having different focus Processing images of a scene taken with different focus includes, for each of at least some of the images, determining at least one portion of the image having a predetermined characteristic. A representation of the scene is generated that includes an array of eleme... | 03/26/2013 |
| 8404747 | Compositions and methods for modulating interaction between polypeptides The present invention is based, in part, on assays we conducted that revealed compounds that may be used to treat or prevent diseases characterized by an abnormal or undesirable association of one protein with another. ... | 03/26/2013 |
| 8401398 | Modulator for frequency-shift keying of optical signals Described are an FSK modulator and a method for large-alphabet FSK modulation. The FSK modulator and the method are based on filtering of a multi-tone optical source such as a mode-locked laser which provides a comb distribution of tones. A frequency-selective compo... | 03/19/2013 |
| 8400024 | Wireless energy transfer across variable distances Described herein are embodiments of transferring electromagnetic energy that includes a first electromagnetic resonator receiving energy from an external power supply, said first resonator having a resonant frequency ω1, an intrinsic loss rate Γ1 | 03/19/2013 |
| 8400023 | Wireless energy transfer with high-Q capacitively loaded conducting loops Described herein are embodiments of a source resonant structure and a device resonant structure, the structures may be capable of performing wireless near-field energy transfer when separated a distance D from each other, where the absolute value of the difference o... | 03/19/2013 |
| 8400022 | Wireless energy transfer with high-Q similar resonant frequency resonators Described herein are embodiments of transferring electromagnetic energy that includes providing a first electromagnetic resonator structure receiving energy from an external power supply, said first resonator structure having a first mode with a resonant frequency Ï... | 03/19/2013 |
| 8400021 | Wireless energy transfer with high-Q sub-wavelength resonators Described herein are embodiments of transferring electromagnetic energy that includes a first electromagnetic resonator structure receiving energy from an external power supply, said first resonator structure may have a first mode with a resonant frequency ω1 | 03/19/2013 |
| 8400020 | Wireless energy transfer with high-Q devices at variable distances Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, and a second high-Q resonator, optionally coupled to an energy drain that may be located a variable distance from the source resonator. The source resonator and th... | 03/19/2013 |
| 8400019 | Wireless energy transfer with high-Q from more than one source Described herein are embodiments of a source high-Q resonator, optionally coupled to an energy source, a second source high-Q resonator, optionally coupled to an energy source, and a third high-Q resonator, optionally coupled to an energy drain, where at least one o... | 03/19/2013 |