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...Daniel Webster invented a "bull plow" to pull out tree stumps. It didn't catch on because it was huge and required four oxen to pull it!
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| Number | Title | Issue Date |
| 7838024 | Methods and devices for the sustained release of multiple drugs The invention relates to an drug delivery device and a method for delivering multiple drugs over a prolonged period of time. The drug delivery device has two or more unitary segments comprising a drug-permeable polymeric substance, wherein at least one of the segmen... | 11/23/2010 |
| 7550441 | Controlled release polymer nanoparticle containing bound nucleic acid ligand for targeting The present invention relates to a conjugate that includes a nucleic acid ligand bound to a controlled release polymer system, a pharmaceutical composition that contains the conjugate, and methods of treatment using the conjugate. The controlled release polymer syst... | 06/23/2009 |
| 7452703 | Uranium enrichment using microorganisms The present invention provides methods for separating isotopes of actinide elements such as uranium using microorganisms, e.g., metal or sulfate reducing bacteria. The microorganisms reduce the actinide element to form a precipitate, which contains a greater proport... | 11/18/2008 |
| 7411331 | Dielectric elastomer actuated systems and methods The system of the present invention includes an actuator having at least two electrodes, an elastomeric dielectric film disposed between the two electrodes, and a frame attached to the elastomeric dielectric film. The frame provides a linear actuation force characte... | 08/12/2008 |
| 6420122 | Methods of screening for agents that inhibit aggregation of polypeptides Methods of identifying compounds that disrupt aggregation of aggregation-disposed polypeptides, such as huntingtin or beta-amyloid protein, are disclosed. Furthermore, an artificial polypeptide that contains an extended polyglutamine region and DNA that e... | 07/16/2002 |
| 6127177 | Controlled reversible poration for preservation of biological materials A preservation method for biological material having cell membranes includes reversibly porating the cell membranes; loading a bio-protective agent having bio-preservation properties to a predetermined intracellular concentration; preparing the bio-protec... | 10/03/2000 |
| 6111645 | Grating based phase control optical delay line An apparatus for performing high speed scanning of an optical delay and its application for performing optical interferometry, ranging, and imaging, including cross sectional imaging using optical coherence tomography, is disclosed. The apparatus achieves... | 08/29/2000 |
| 5924261 | Method and apparatus for damping structural vibrations The damped structural member includes a structural member and granular material in intimate contact with the member. In one embodiment the granular material is lightweight and has a bulk specific gravity of less than 1.5. When low weight is important, the... | 07/20/1999 |
| 5759830 | Three-dimensional fibrous scaffold containing attached cells for producing vascularized tissue in vivo A cell-scaffold composition is prepared in vitro for implanting to produce functional organ tissue in vivo. The scaffold is three-dimensional and is composed of fibers of a biocompatible, biodegradable, synthetic polymer. Cells derived from vascularized o... | 06/02/1998 |
| 5742373 | Color microdisplays and methods of manufacturing same A color microdisplay utilizes diffraction gratings to provide an array of high efficiency color pixels. The microdisplay includes a semiconductor substrate and source of light disposed adjacent thereto. A cover plate may be disposed above the substrate an... | 04/21/1998 |
| 5580929 | Interpenetrating-polymer network phase-transition gels An interpenetrating gel and a method of forming an interpenetrating gel which undergoes a significantly large volume change in response to a physical or chemical stimululs is disclosed.... | 12/03/1996 |
| 5526446 | Noise reduction system A technique is provided to remove noise from images and to enhance their visual appearance through the utilization of a technique which converts an image into a set of coefficients in a multi-scale image decomposition process, followed by modification of ... | 06/11/1996 |
| 5440062 | Enantioselective addition of hydrocarbons to alpha,beta-unsaturated carbonyl compounds The conjugate addition of hydrocarbon equivalents to alpha,beta-unsaturated carbonyl compounds using a series of novel catalysts is described. The catalysts comprise copper(I) complexes with ligand systems comprising either tropocoronand macrocycles or N,... | 08/08/1995 |
| 5348879 | Cell stretching method Disclosed is a method for imparting to a living culture of cells biaxial mechanical forces which approximate the mechanical forces to which cells are subject in vivo. The method utilizes a displacement applicator which may be actuated to contact and stret... | 09/20/1994 |
| 5034010 | Optical shield for a laser catheter A laser catheter is disclosed wherein optical fibers carrying laser light are mounted in a catheter for insertion into an artery to provide controlled delivery of a laser beam for percutaneous intravascular laser treatment of atherosclerotic disease. A tr... | 07/23/1991 |
| 4786718 | Method of preparing antibodies to characterize oncogenes Experiments designed to define the differences between the 21 oncogene of DNA isolated from human bladder cancer cells and its corresponding proto-oncogene are described herein. By a series of in vitro recombinations, the difference was initially isolated... | 11/22/1988 |
| 4740463 | Methods and artificial genes for antagonizing the function of an oncogene A method of antagonizing the effects of an oncogene by constructing an artificial gene which antagonizes the function of the oncogene is described herein. In one embodiment, the artificial gene comprises a transcriptional promoter segment, an inverted onc... | 04/26/1988 |
