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"What, sir, would you make a ship sail against the wind and currents by lighting a bonfire under her deck? I pray you, excuse me, I have not the time to listen to such nonsense."
Napoleon Bonaparte ; When told of the Robert Fulton steamboat
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| Number | Title | Issue Date |
| 7880465 | Method and apparatus for contrast inflow dynamic MR angiography A system and method for MR imaging includes a computer programmed to determine first and second view-ordering sequences. The first and second view-ordering sequences comprise values corresponding to respective views of first and second k-space data sets, respectivel... | 02/01/2011 |
| 7745155 | In-vivo monitoring of circulating apoptotic cells The present invention provides methods and systems for performing in vivo flow cytometry. In one embodiments, selected circulating cells of interest of a subject are labeled with fluorescent probe molecules. The labeled cells are irradiated in-vivo so as to excite t... | 06/29/2010 |
| 7632812 | Methods to stimulate insulin production by pancreatic β-cells The invention features a method of treating deficiency of insulin in a patient, comprising administering to a patient in need thereof hedgehog protein or nucleic acid in an amount effective to raise the level of insulin in the patient. ... | 12/15/2009 |
| 7569620 | High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene... | 08/04/2009 |
| 7498130 | Method of reducing viral load Methods of activating ATIII in situ in a blood product are disclosed, as is the use of such methods and blood products in treating infectious diseases, inflammatory disorders and diseases or conditions that are mediated by thrombin activation. ... | 03/03/2009 |
| 7431874 | Methods for making oxidation resistant polymeric material The present invention relates to methods for making oxidation resistant medical devices that comprise polymeric materials, for example, ultra-high molecular weight polyethylene (UHMWPE). The invention also provides methods of making antioxidant-doped medical implant... | 10/07/2008 |
| 7304097 | High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene... | 12/04/2007 |
| 7205339 | Selective controlled manipulation of polymers The present invention provides partial and complete shielding approaches to alter the cross-linking characteristics of irradiated polymers, such as polyethylene. Irradiated polymers and fabricated articles, such as medical prosteses, comprising irradiated polymers a... | 04/17/2007 |
| 7204801 | Pubovaginal support for treating female urinary incontinence A device to be surgically inserted for providing bulk and stiffness supporting the urethra. A preferred embodiment is shaped like a capital letter “T.” The extensions of the T are wide compared to the patient's anterior vagina and urethra. The pubovaginal suppor... | 04/17/2007 |
| 7169186 | Monopolar constrained acetabular component The present invention provides monopolar acetabular liners that can enclose a femoral head to form a hip replacement prosthesis, wherein the liner has a rim that creates an orifice, wherein the orifice has a diameter that is smaller than the diameter of the femoral ... | 01/30/2007 |
| 7166650 | High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene... | 01/23/2007 |
| 6875224 | Devices and methods for percutaneous mitral valve repair Devices and methods are provided for diagnosing and repairing mitral valve defects such as mitral valve regurgitation. According to an exemplary method, mitral valve function is visualized by transesophageal echocardiography. A catheter is inserted along the venous ... | 04/05/2005 |
| 6852772 | High modulus crosslinked polyethylene with reduced residual free radical concentration prepared below the melt The present invention provides an irradiated crosslinked polyethylene containing reduced free radicals, preferably containing substantially no residual free radical. Disclosed is a process of making irradiated crosslinked polyethylene by irradiating the polyethylene... | 02/08/2005 |
| 6262248 | RPS gene family, primers, probes, and detection methods Disclosed is substantially pure DNA encoding an Arabidopsis thaliana Rps2 polypeptide; substantially pure Rps2 polypeptide; and methods of using such DNA to express the Rps2 polypeptide in plant cells and whole plants to provide, in transgenic plants, dis... | 07/17/2001 |
| 6214553 | Libraries of protein encoding RNA-protein fusions Described herein are methods and reagents for the selection of protein molecules that make use of RNA-protein fusions.... | 04/10/2001 |
| 6120497 | Method and apparatus for treating wrinkles in skin using radiation A method for treating wrinkles in skin involves the use of a beam of pulsed, scanned or gated continuous wave laser or incoherent radiation. The method comprises generating a beam of radiation, directing the beam of radiation to a targeted dermal region b... | 09/19/2000 |
| 5978505 | System and method for image regularization in inhomogeneous environments using clustering in neural networks A regularization system and method for image restoration in homogeneous or inhomogeneous environments. The system and method includes features similar to a neural network with intermediate levels of structure including a pixel having processing capabiliti... | 11/02/1999 |
| 5301673 | Ambulatory clearance function monitor Accurate and continuous monitoring of clearance function is obtained by determining the depletion of a labelled substance from the extracellular body fluid using an external monitor which detects label from within a defined tissue volume. The detector of ... | 04/12/1994 |
| 5179639 | Computer display apparatus for simultaneous display of data of differing resolution A multiple memory display controller provides simultaneous display of overlaid image and graphic data in a computer display system. A video random access memory (RAM) in the display controller stores display data corresponding to graphics to be displayed ... | 01/12/1993 |
| 5179651 | Apparatus for retrieval and processing of selected archived images for display at workstation terminals An image processing and display system employs a high speed image local area network (LAN) for transferring image data separate from control data. A general purpose LAN carries graphics data and control data of the system. One more image display controlle... | 01/12/1993 |
| 5154903 | Treatment of asbestos and silicates to reduce their toxicity This invention pertains to an improved method of inhibiting peroxide-reduction catalytic activity and concomitant toxicity of asbestos and nonasbestos iron-containing silicates. These undesirable reactions can be substantially reduced or essentially elimi... | 10/13/1992 |
| 5046027 | Apparatus and method for processing and displaying images in a digital procesor based system An image processing and display system employs a high speed image LAN (Local Area Network) for transferring image data separate from control data. A general purpose LAN carries graphics data and control data of the system. One more image display controlle... | 09/03/1991 |
| 4973669 | Monoclonal IgM antibody with specificity against hepatitis B surface antigen The monoclonal antibodies are specific for a determinant found on hepatitis B surface antigen, and show high affinity for this determinant. Hybridomally produced monoclonal IgM antibodies having high affinity are useful for the immunoassay and purificatio... | 11/27/1990 |
| 4676252 | Double indicator pulmonary edema measurement Patient monitoring method and apparatus for measurement of in vivo extra vascular lung water (pulmonary edema) and pulmonary circulatory system thermal bypass utilizing double indicator dilution with temperature and electrical conductivity modifiers. A th... | 06/30/1987 |
| 4657932 | Method of treating prolactin-related disorders A method of decreasing the concentration of prolactin in an animal, which comprises administering to the animal a prolactin-decreasing amount of cysteamine.... | 04/14/1987 |
| 4626513 | Method and apparatus for ligand detection A process and apparatus has been developed for radioassay of ligand in solution which eliminates the separation step required in conventional techniques. A chamber is provided containing a quenching solution, a plurality of ligand molecules and a pluralit... | 12/02/1986 |
| 4581030 | Collagen replacement prothesis for the cornea This invention relates to a prosthetic replacement for the cornea and particularly to a transparent collagen material useful for making such a prosthesis and to methods for making such transparent collagen material. The prosthesis is preferably composed o... | 04/08/1986 |
| 4537128 | Hand printer designed to enable a handicapped person to apply a signature to a document A system designed to enable persons incapable of manipulating a writing implement to sign papers and/or documents comprising a holder for the document to be signed, a holder for a transfer sheet for holding the transfer sheet adjacent that portion of the ... | 08/27/1985 |
| 4505855 | Transparent non-fibrilized collagen material by ultracentrifugation A transparent native, non-fibrilized collagen material is described having an absorbence at a wavelength of 900 nm of less than 5% in a sample 5 mm thick. This collagen material is useful for a prosthetic replacement of the cornea because of the high tran... | 03/19/1985 |
| 4469706 | Selective beta-2 adrenergic antagonists for the treatment of glaucoma A method of decreasing the intraocular pressure in the eye of an animal which comprises administering to the animal an intraocular pressure decreasing amount of a beta2 adrenergic receptor antagonist having a 댢 /댡 | 09/04/1984 |
| 4424161 | [1ଲ3 H] 1,25 Dihydroxyvitamin D3 and method for its preparation [1ଲ-3 H] 1,25 dihydroxyvitamin D3 of high specific activity as well as a method for its preparation, which comprises reducing 1-keto 25(OH) previtamin D3 with 3 H-NaBH4, separating the [1... | 01/03/1984 |
| 4419585 | Variable angle slant hole collimator A variable angle radiation collimator particularly for use in gamma-photon medical diagnostic systems in a gamma-photon camera system for radiological examination of human subjects. The collimator provides collimation of gamma-photon radiation along a sin... | 12/06/1983 |
| 4410515 | Vitamin D glycosides and a method of use A synthetic compound which is biologically active in maintaining calcium and phosphorous metabolism in animals, of the formula I ##STR1## wherein the double bond between positions C-22 and C-23 is single or double; R2 is hydrogen, CH3... | 10/18/1983 |
| 4404188 | Purified Mullerian Inhibiting Substance and method of purification A process for purifying Mullerian Inhibiting Substance (MIS) from testicular tissue which comprises incubating testicular tissue in a culture media in the presence of a protease inhibitor in order to extract MIS from the tissue, chromatographing the extra... | 09/13/1983 |
| 4380237 | Apparatus for making cardiac output conductivity measurements An improved catheter probe includes a conductivity sensor comprising four electrodes configured and spaced to be electrically coupled together by vascular fluids. A current source is provided for driving current through the vascular fluid between one pair... | 04/19/1983 |
| 4338293 | Sunscreening agent A sunscreening composition which comprises a sunscreening amount of a Ɗ5,7 steroidal diene and a topical carrier, with the proviso that the Ɗ5,7 steroidal diene is not a precursor to a biologically active vitamin D compound.... | 07/06/1982 |
| 4310511 | Sunscreen compositions containing Ɗ5,7 steroidal dienes A sunscreening composition which comprises a sunscreening amount of an opacifying agent and a therapeutic amount of a Ɗ5,7 steroidal diene which is non-hydroxylated at any of positions 1; 1,25; 1,24,25 or 1,25,26 thereof.... | 01/12/1982 |
| 4236527 | Cardiac output detection by multiple frequency thermodilution Method and apparatus for measuring cardiac output in which a traceable signal in the form of thermal energy or an injectate is applied to the blood flow through the heart having a plurality of frequency components with the traceable signal detected at a h... | 12/02/1980 |
| 4235906 | Bis-isoquinolinium compounds, compositions and methods of use Intermediate-duration reversible neuromuscular blocking agents of the formula (I) ##STR1## where B and C are preferably para or may be meta and are each ##STR2## where W is CH2 or most preferably CH.dbd.CH R1, R2... | 11/25/1980 |
| 4192877 | Neuromuscular blocking agents Short acting reversible neuromuscular blocking agents of the formula (I) ##STR1## where B and C is preferably meta or maybe para ##STR2## where m is 2, 3 or 4 and is preferably 2, R1, R2, R3, R4, R5 | 03/11/1980 |
