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| Number | Title | Issue Date |
| 7960514 | IL-7 fusion proteins The invention is directed to a fusion protein which includes a first portion including an immunoglobulin (Ig) chain and a second portion including interleukin-7 (IL-7). ... | 06/14/2011 |
| 7960430 | Flavonoid complexes with cyclodextrins The invention relates to complexes of certain flavonoid derivatives, of the formula I compositions which comprise such derivatives, corresponding processes for the preparation of the flavonoid derivatives or of compositions comprising same, and the use thereof, in p... | 06/14/2011 |
| 7943608 | Diazepinoes The invention relates to compounds of the formula (I), to the preparation and use thereof for the preparation of a medicament for the treatment of diseases, in particular tumours and/or diseases in the development or course of which kinases are involved. | 05/17/2011 |
| 7939644 | Cyanoborate, fluoroalkylphosphate, fluoroalkylborate or imide dyes The present invention relates to dyes of the general formula CAT+ Y− (I), where Y− is an anion selected from the group of the cyanoborates, fluoroalkylphosphates, fluoroalkylborates or imidates and CAT+ is a cation sel... | 05/10/2011 |
| 7939295 | Methods for reducing immunogenicity of polypeptides This invention relates to the fields of immunology and protein therapeutics. The therapeutic proteins are polypeptides to be administered especially to humans. The polypeptides are modified whereby the modification results in a reduced propensity for the polypeptide... | 05/10/2011 |
| 7936426 | Transflective LCD comprising a patterned retardation film The invention relates to a transflective liquid crystal display (LCD) with a polymerised LC film comprising at least one photoisomerisable compound and having a pattern of regions with different retardation and/or different orientation of the LC material. ... | 05/03/2011 |
| 7935960 | Polyacene and semiconductor formulation The invention relates to novel polyacene compounds, organic semiconducting formulations and layers comprising them, a process for preparing the formulation and layer and electronic devices, including organic field effect transistors (OFETs), comprising the same.... | 05/03/2011 |
| 7935347 | DNA sequence, and recombinant preparation of group 4 major allergens from cereals The invention relates to the preparation of DNA sequences of group 4 major allergens from cereals. The invention also includes fragments, novel combinations of partial sequences and point mutations with hypoallergenic effects. The recombinant DNA molecules and the d... | 05/03/2011 |
| 7932401 | 1,5-diphenylpyrazoles Novel 1,5 diphenylpyrazole derivatives of the formula (I), in which R1-R6 have the meanings indicated in Claim 1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibit... | 04/26/2011 |
| 7928466 | Light emitting semi-conductor diode (with high light output) A light-emitting semi-conductor diode comprising a light emitting chip at least partially surrounded by a transparent electronics protecting body on which a composite layer foil is disposed, the composite layer foil includes at its side facing away from the electron... | 04/19/2011 |
| 7927717 | Electroluminescent materials and devices Electroluminescent devices have an electroluminescent layer incorporating iridium complexes with 2-benzo[b]thiophenyl and benzimidazole ligands such as bis[thiophen-2-yl-pyridine-C2,N′]-2-(2-pyridyl)-benzimidazole iridium. ... | 04/19/2011 |
| 7923521 | Process for preparing ortho-metallated metal compounds The present invention describes a process for the preparation of homoleptic and heteroleptic tris-ortho-metallated metal compounds which are used as coloring components as functional materials in a number of different applications which can be ascribed to the electr... | 04/12/2011 |
| 7923079 | Liquid-crystalline medium and liquid-crystal display comprising 1,2-difluoroethene compounds The present invention relates to a liquid-crystalline medium comprising 1,2-difluoroethene compounds of the general formula I, in which R1, ring A, Z1, Z2, m, X and L1-6 are as defined in Claim 1. The invention also... | 04/12/2011 |
| 7920233 | Transflective vertically aligned liquid crystal display with in-cell patterned quarter-wave retarder The invention relates to a transflective vertically aligned (VA) liquid crystal display (LCD) comprising a patterned quarter wave foil (QWF). The display (10) comprises, in a particular, front and back electrodes (14a, 14b, 14 | 04/05/2011 |
| 7915416 | Tetrahydroquinolines Disclosed are compounds of formula (I), wherein W, R, R1, R2, R3, R4, R5, R6, and R7 have the meanings indicated in claim 1. Said compounds can be used for the treatment of tumors, a... | 03/29/2011 |
| 7914893 | Particles comprising an anion-binding layer containing anion-forming organic active compounds, and method of making and using thereof Disclosed are particles containing substrates and an anion-binding layer, containing one or more anion-forming organic active compounds or active compound/colorant mixtures; processes for preparing said particles and to methods of use thereof in cosmetics, pharmaceu... | 03/29/2011 |
| 7914859 | Mesogenic compounds, liquid crystal medium and liquid crystal display The instant invention relates to mesogenic media comprising one or more compounds which comprise two or more mesogenic groups two of which are linked to the ortho-positions of an aromatic ring, preferably of formula (I) wherein the parameters are as specified in the... | 03/29/2011 |
| 7910104 | Modified anti-CD52 antibody The present invention provides for modified forms of anti-CD52 antibodies with reduced numbers of potential T-cell epitopes that are expected to display decreased immunogenicity. ... | 03/22/2011 |
| 7906516 | Carbonyl compounds Novel compounds of the formula (I), in which D, E, G, W, X, Y, T, R1 and R2 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and f... | 03/15/2011 |
| 7906178 | Hardening and drying of lacquer systems and printing colors The invention relates to the use of light-colored or transparent particulate semiconductor materials or particulate substrates that are coated with said semiconductor materials as a hardening and/or drying additive and/or for increasing the thermal conductivity of l... | 03/15/2011 |
| 7902223 | Phenyl derivatives as factor XA inhibitors Novel compounds of the formula (I), in which D, W, X, Y, T and R1 are as defined in Patent Claim 1, are inhibitors of coagulation factor Xa and can be employed for the prophylaxis and/or therapy of thromboembolic diseases and for the treatment of t... | 03/08/2011 |
| 7902186 | Substituted 5-phenyl-3,6-dihydro-2-oxo-6H-1,3,4-thiadiazines Compounds of the formula (I), in which R1, R2, m, Q and B have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter alia, for the treatment of tumours. | 03/08/2011 |
| 7901766 | Electronic devices comprising an organic conductor and semiconductor as well as an intermediate buffer layer made of a crosslinked polymer The invention relates to electronic devices whose electronic properties can surprisingly be improved to a significant degree by inserting at least one crosslinkable polymeric buffer layer, preferably a cationically crosslinkable polymeric buffer layer, between the c... | 03/08/2011 |
| 7893253 | Solid-phase oligosaccharide tagging: a technique for manipulation of immobilized carbohydrates The invention relates to methods of manipulating immobilised carbohydrates by derivatisation. Depending on the nature of the derivatisation, the carbohydrate may thereby be more easily detected and/or identified or handled. In particular, the invention relates to me... | 02/22/2011 |
| 7893172 | Oligomer and polymer comprising triphenyl phosphine units An oligomer or polymer comprising a first repeat unit and a second repeat unit that may be the same or different, the first repeat unit having formula (I): wherein each E independently represents optionally substituted nitrogen or optionally substituted phosphorus, ... | 02/22/2011 |
| 7893082 | Substituted tetrahydroquinolines Disclosed are compounds of formula (I), wherein W, R, R1, R2, R3, R4, R5, R6, and R7 have the meanings indicated in claim 1. Said compounds can be used for the treatment of tumors, a... | 02/22/2011 |
| 7888071 | DNA encoding IL-2 fusion proteins with modulated selectivity The invention provides cytokine fusion proteins with an increased therapeutic index, and methods to increase the therapeutic index of such fusion proteins. The fusion proteins of the invention are able to bind to more than one type of cytokine receptor expressed on ... | 02/15/2011 |
| 7887933 | Electroluminescent materials and devices An electroluminescent composition is provided comprising: (a) a compound of the general chemical formula (I): wherein M is lithium, sodium, potassium, rubidium, caesium, beryllium, magnesium, calcium, strontium, barium, cop... | 02/15/2011 |
| 7887849 | Pigment mixture The invention relates to a pigment mixture consisting of at least two constituents, constituent A being uncoated, monocoated or multicoated glass lamellae, and constituent B being nacreous pigments based on phyllosilicates, SiO2 lamellae, Fe2O | 02/15/2011 |
| 7884126 | Indazole-heteroaryl derivatives The invention relates to novel indazole derivatives as cited in claim 1, which are inhibitors of CHK1, CHK2 and SGK kinases and can be used to treat cancer and other diseases. ... | 02/08/2011 |
| 7880379 | Phosphorescent organic electroluminescent device having no hole transporting layer The invention relates to the improvement of phosphorescing organic electroluminescent devices characterized in that the emission layer, which consists of a matrix material which is doped with at least one phosphorescing emitter, directly adjoins an electrically cond... | 02/01/2011 |
| 7846927 | N,N′-diphenylurea derivatives suitable as kinase inhibitors Compounds of the formula (I), in which R1, R3 and X have the meanings indicated in Claim 1, are inhibitors of tyrosine kinases, in particular TIE-2, and Raf kinases and can be employed, inter alia, for the treatment of tumours. | 12/07/2010 |
| 7846448 | DNA sequence, and recombinant preparation of the grass pollen allergen Lol p4 The present invention relates to the provision of a DNA sequence of the major grass pollen allergen Lol p 4. The invention also encompasses fragments, new combinations of partial sequences and point mutants having a hypoallergenic action. The recombinant DNA molecul... | 12/07/2010 |
| 7875644 | 1-acyldihydropyrazole derivatives Compounds of the formula (I), in which R1, R2, R3a, R3b, R3c and R3d have the meanings indicated in claim 1, are inhibitors of tyrosine kinases, in particular Met kinase, and can be employed, inter al... | 01/25/2011 |
| 7875614 | Phthalazinones Compounds of the formula I, in which R, R1, R2, R3, R4, R5, R6, R7, R8, Z1, Z2, Z3 and Y1 have the meanings indicated in claim 1 | 01/25/2011 |
| 7875112 | Effect pigments that are surface-modified with LCST and/or UCST polymers The present invention relates to surface-modified effect pigments based on flake-form substrates which are distinguished by the fact that they are sheathed with one or more layers of immobilised LCST and/or UCST polymers. The invention furthermore relates to a proce... | 01/25/2011 |
| 7872107 | Interleukin-12p40 variants with improved stability Modified interleukin-12 (IL-12) p40 polypeptides are disclosed. The modified polypeptides have alterations in the IL-12p40 subunit to eliminate the protease site between positions Lys260 and Arg261. The modified IL-12p40 polypeptides according to the invention have ... | 01/18/2011 |
| 7872030 | Use of 2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane and its physiologically acceptable salts (R/S)-(−/+)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane or a physiologically acceptable salt thereof and/or (S)-(+)-2-[5-(4-fluorophenyl)-3-pyridylmethylaminomethyl]-chromane or a physiologically acceptable salt thereof are used for the manufacture ... | 01/18/2011 |
| 7868172 | 2-(hetero)-aryl substituted tetrahydroquinoline derivatives Compounds of the formula I, in which W, R, R1, R2, R3, R4, R5, R6 and R7 have the meanings indicated in Claim 1, can be employed, inter alia, for the treatment of tumours | 01/11/2011 |
| 7867993 | Preparation containing oxidized flavonoid derivatives The invention relates to novel compositions, in particular cosmetic and/or pharmaceutical compositions or food supplements, comprising at least one oxidized flavonoid derivative of the formula I, to novel oxidized flavonoid derivatives, and to novel uses of the oxid... | 01/11/2011 |
