Did You Know...
...that the Band-Aid Bandage was invented by a Johnson & Johnson employee whose wife had cut herself? Earl Dickson's wife was rather accident prone, so he set out to develop a bandage that she could apply without help. He placed a small piece of gauze in the center of a small piece of surgical tape, and what we know today as the Band Aid bandage was born!
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| Number | Title | Issue Date |
| 8173803 | Supramolecular scaffolds and methods of making the same Tribenzo-1,4,7-triazacyclononane and derivatives thereof having a formula (I) are disclosed. Methods of making tribenzo-1,4,7-triazacyclononane and related compounds also are disclosed. ... | 05/08/2012 |
| 7754430 | Papilloma virus capsomere vaccine formulations and methods of use Vaccine formulations comprising viral capsomeres are disclosed along with methods for their production. Therapeutic and prophylactic methods of use for the vaccine formulations are also disclosed. ... | 07/13/2010 |
| 7632973 | Methods for preparing aldehydes by self-aldol condensation Methods for preparing self-aldol condensation products of prenyl aldehyde (3-methyl-2-butenal) by use of an amine catalyst under weakly acidic conditions at temperatures of 10° C. or higher are disclosed. Methods are disclosed for the selective formation of α-1,2-... | 12/15/2009 |
| 7416732 | Papilloma virus-like particles, fusion proteins as well as processes for their production The invention relates to the recombinant production of proteins as well as VLPs which are suitable as a vaccine for therapeutic and prophylactic vaccination. The invention also relates to processes for the production and purification of recombinant papilloma virus p... | 08/26/2008 |
| 7371391 | Papilloma virus capsomere vaccine formulations and methods of use Vaccine formulations comprising viral capsomeres are disclosed along with methods for their production. Therapeutic and prophylactic methods of use for the vaccine formulations are also disclosed. ... | 05/13/2008 |
| 6909010 | Facile synthesis of symmetric esters of alkylenebisphosphonic acids A facile synthesis of symmetric esters of C1-C10 alkylenebisphopsphonic acids is disclosed in which a C1-C10 alkylenebis(phosphonic dichloride) is reacted with an alcohol in the presence of a catalytic amount of 1H-tetrazo... | 06/21/2005 |
| 6599508 | Papilloma virus-like particles, fusion proteins as well as processes for their production The invention relates to the recombinant production of proteins as well as VLPs which are suitable as a vaccine for therapeutic and prophylactic vaccination. The invention also relates to processes for the production and purification of recombinant papill... | 07/29/2003 |
| 6559359 | Plant retroviral polynucleotides and methods for use thereof Retroviral and retroviral-like polynucleotides, and vectors, proteins, and antibodies derived therefrom, that are useful for the introduction of genetic information into soybeans and other plant species.... | 05/06/2003 |
| 6278016 | Methods for conversion of isoprene to prenyl alcohol and related compounds Methods for preparing ester derivatives of 3-methyl-2-buten-1-ol (prenyl alcohol) from 2-methyl-1,3-butadiene (isoprene) and alkanoic acids in the presence of an inorganic acid catalyst are disclosed. The resultant prenyl ester (e.g., prenyl acetate) can ... | 08/21/2001 |
| 6242176 | Papillomavirus cellular receptor The present invention provides methods and reagents for treating or preventing papillomavirus infection. In one aspect, the invention provides reagents and methods for attenuating the ability of papillomavirus to bind to cells by blocking access of papill... | 06/05/2001 |
| 6228368 | Papilloma virus capsomere formulations and method of use Vaccine formulations comprising viral capsomeres are disclosed along with methods for their production. Therapeutic and prophylactic methods of use for the vaccine formulations are also disclosed.... | 05/08/2001 |
| 6066324 | Carboxyl terminal of papilloma virus L1 region is not required for formation of virus-like particles Recombinant papilloma virus-like particles result from the expression of viral structural protein L1 and/or L2 in which one or several sections of the L1 and/or L2 protein are deleted. The ability to form virus-like particles is at least the same as, pref... | 05/23/2000 |
| 6049010 | Method of preparing 3-(3-methyl-2-buten-1-yl)-2,4-pentanedione and related dicarbonyl compounds A method for preparation of a dicarbonyl compound of the following formula ##STR1## by reacting a conjugated alkadiene compound of the formula ##STR2## with a 1,3-dicarbonyl compound of the formula ##STR3## in the presence of an acid cataly... | 04/11/2000 |
| 5973179 | C-15 phosphonate reagent compositions for the manufacture of compounds such as lycopene and methods of synthesizing the same The present invention describes novel phosphonate reagent compositions of the formula: ##STR1## wherein R and R'=C1 -C4 alkyl groups, or R, R'=(CH2)n (n=2 or 3) or [CH2 C(CH3)2 | 10/26/1999 |
| 5952519 | C-15 phosphonate reagent compositions for the manufacture of compounds such as canthaxanthin and methods of synthesizing the same The present invention describes novel C-15 allenic phosphonate reagent compositions of the formula: ##STR1## The invention also describes novel C-15 allylic phosphonate reagent compositions of the formula: ##STR2## The invention also descri... | 09/14/1999 |
| 5872277 | Methods for preparing prenyl alcohol Methods for preparing 3-methyl-2-buten-1-ol (prenyl alcohol) from 2-methyl-1,3-butadiene (isoprene) and carboxylic acids are disclosed. Carboxylic acids which can be used in the process have a Ka (relative to water) greater than 10-4... | 02/16/1999 |
| 5847185 | C-15 phosphonate reagent compositions and methods of synthesizing the same Allenic phosphonate reagent compositions are described which have the formula: ##STR1## wherein R and R'=C1 -C4 alkyl groups, or R, R'=(CH2)n (n=2 or 3) or CH2 C(CH3)2 CH | 12/08/1998 |
| 5824226 | Silane-modified clay Clay particles with organo silane-modified surfaces are provided along with a process for their preparation. The silane-modified clay is relatively easily and reliably produced by reacting clay with a R-substituted halosilane (R being a hydrophobic group)... | 10/20/1998 |
| 5656603 | Aminopeptidase P inhibitors and uses thereof The present invention is directed to a compound of the formula: ##STR1## or a pharmaceutically acceptable addition salt thereof, wherein C3 and C2 in combination have the configuration S,R or R,S; wherein Y is straight or branched ch... | 08/12/1997 |
| 5605931 | Protective prostaglandins for use in conjunction with chemotherapeutic agents Prostaglandins of the PGE type can be administered in a therapeutically effective amount to protect tissue from injury resulting from chemotherapeutic agents by administering the PGE-type prostaglandin prior to administration of the chemotherapeutic agent... | 02/25/1997 |
| 5599307 | Catheter and method for the prevention and/or treatment of stenotic processes of vessels and cavities A catheter for preventing the stenosis or restenosis of a body vessel or cavity, e.g., a blood vessel, whereby a membrane may be applied to the inner surface of the vessel or cavity. The inventive catheter tip utilizes (a) two inflatable chamber balloons ... | 02/04/1997 |
| 5578640 | Protective prostaglandins for use in conjunction with chemotherapeutic agents Prostaglandins of the PGE type can be administered in a therapeutically effective amount to protect tissue from injury resulting from chemotherapeutic agents by administering the PGE-type prostaglandin prior to administration of the chemotherapeutic agent... | 11/26/1996 |
| 5578643 | Protective prostaglandins for use in conjunction with chemotherapeutic agents Prostaglandins of the PGE type can be administered in a therapeutically effective amount to protect tissue from injury resulting from chemotherapeutic agents by administering the PGE-type prostaglandin prior to administration of the chemotherapeutic agent... | 11/26/1996 |
| 5471005 | Method of making 2,7-dimethyl-2,4,6-octatrienedial, a key intermediate in the commercial syntheses of various carotenoids A procedure for forming methylmalonaldehyde from propionaldehyde, an alkyl formate and a sodium alkoxide, utilizing a crossed-Claisen condensation is disclosed. The procedure avoids the formation of aldol condensation products. Also disclosed are processe... | 11/28/1995 |
| 5410094 | Tertiary alkynols Processes for synthesizing tertiary alkynols by reacting carbonyl-group-containing compounds with alkynes in the presence of a basic catalyst are disclosed. Preferred products are 6,10,14-trimethyl-4-pentadecyn-6-ol compounds having the structure: ##... | 04/25/1995 |
| 5349071 | Process for preparing tertiary alkynols Processes for synthesizing tertiary alkynols by reacting carbonyl-group-containing compounds with alkynes in the presence of a basic catalyst are disclosed. Preferred products are 6,10,14-trimethyl-4-pentadecyn-6-ol compounds having the structure: ##... | 09/20/1994 |
| 5245024 | Cellulose chromatography support This invention relates to an improved cellulose chromatography support and, in particular, to substantially spherical, high density cellulose particles. This invention also relates to a method of making these spherical, high density cellulose particles an... | 09/14/1993 |
| 5231232 | Method of preparing C-18 ketones used in the manufacture of Vitamins E and K Methods of forming unsaturated C-18 ketones which can be used in the synthesis of Vitamins E and K1 are disclosed. One procedure involves coupling a C-9 primary allylic halide to a carbonyl-group-containing C-9 terminal alkyne. A second, two-st... | 07/27/1993 |
| 5191127 | Glyoxal derivatives and method for making the same This invention provides glyoxal derivatives and a method for making these derivatives. A particularly useful derivative, 1-chloro-1,2,2-trialkoxyethane, and a facile method for making these alpha-halo ethers are provided. The alpha-halo ethers are valuabl... | 03/02/1993 |
| 5107030 | Method of making 2,7-dimethyl-2,4,6-octatrienedial and derivatives thereof The present invention is an improved method to prepare 2,7-dimethyl-2,4,6-octatrienedial and related derivative compounds. This method of making 2,7-dimethyl-2,4,6-octatrienedial and derivatives thereof includes reacting 2-butenyl-bisphosphonic acid tetra... | 04/21/1992 |
| 5061819 | Methods for synthesizing phosphonate reagents and retinoids Processes for synthesizing novel phosphonate diester compounds of the general formula ##STR1## are disclosed and claimed. The claimed process includes forming a reaction mixture of a C-14 aldehyde and a methylene-bis-phosphonic acid ester, separ... | 10/29/1991 |
| 4916250 | Phosphonate reagent compositions Novel phosphonate compounds of the formula ##STR1## are disclosed and claimed, as well as methods for manufacturing the phosphonates from C-14 through C-16 aldehydes. The phosphonate compounds of the present invention can be employed to form 13-cis r... | 04/10/1990 |
| 4567265 | Cyclopropanoid cyanoesters and method of making same Cyclopropanoid cyanoesters of the formula: ##STR1## where R' is --CH3 or --CH2 CH3, and A is (a) --H, or (b) A, B represents an aliphatic group joined to a carbon atom on the cyclopropanoid ring, thereby forming a spiro gr... | 01/28/1986 |
