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| Number | Title | Issue Date |
| 7442696 | Mineralocorticoid receptor modulator compounds, processes for their preparation, and their uses This invention relates to compounds that bind to mineralocorticoid receptors and/or modulate activity of mineralocorticoid receptors, and to methods for making and using such compounds. Some embodiments relate to compounds of Formula I: | 10/28/2008 |
| 7439027 | Method for modulating process mediated by farnesoid activated receptors Farnesyl pyrophosphate, the metabolically active form of farnesol, is a key precursor in the synthesis of cholesterol, carotenoids, steroid hormones, bile acids and other molecules involved in cellular growth and metabolism. A nuclear receptor has been identified th... | 10/21/2008 |
| 7435733 | Mineralocorticoid receptor modulator compounds and methods, and pharmaceutical compositions containing these compounds This invention relates to compounds that bind to mineralocorticoid receptors and/or modulate activity of mineralocorticoid receptors, and to methods for making and using such compounds. Some embodiments relate to compounds of Formula I: | 10/14/2008 |
| 7314887 | Thrombopoietin activity modulating compounds and methods Disclosed herein are compounds of Formula (I), (II), and (III) pharmaceutical compositions comprising the same, methods of modulating the activity a thrombopoietin receptor using the same, methods of identifying ... | 01/01/2008 |
| 7192982 | Modulators of peroxisome proliferator activated receptors Disclosed is a compound represented by Structural Formula (I): Ar is a substituted or unsubstituted aromatic group. Q is a covalent bond, —CH2— or —CH2CH2—; W is a substituted or unsubstituted alkylene or a substituted or uns... | 03/20/2007 |
| 7098310 | Heterodimers of retinoid X receptors (RXRS) and other steroid hormone receptors This invention provides a purified heterodimer comprising an RXR and a hormone receptor. The invention also provides a method of screening ligands for their effect on the activity of an RXR-containing hormone receptor heterodimer comprising combining the heterodimer... | 08/29/2006 |
| 7026125 | Heterodimers of retinoid X receptors (RXRS) and other steroid hormone receptors This invention provides a purified heterodimer comprising an RXR and a hormone receptor. The invention also provides a method of screening ligands for their effect on the activity of an RXR-containing hormone receptor heterodimer comprising combining the heterodimer... | 04/11/2006 |
| 6696459 | Steroid receptor modulator compounds and methods Non-steroidal compounds which are high affinity, high selectivity modulators for steroid receptors are disclosed. Also disclosed are pharmaceutical compositions incorporating such compounds, methods for employing the disclosed compounds and compositions f... | 02/24/2004 |
| 6667313 | 8-substituted-6-triflouromethyl-9-pyrido [3,2-G] quinoline compounds as androgen receptor modulators Non-steroidal compounds and compositions which are agonists, partial agonists, and antagonists for androgen receptors and methods of preparation for the non-steroidal compounds and compositions.... | 12/23/2003 |
| 6498155 | Methods of treating thrombocytopenia Invented are non-peptide TPO mimetics. Also invented is a method of treating thrombocytopenia, in a mammal, including a human, in need thereof which comprises administering to such mammal an effective amount of a linked cyclic polyamine derivative.... | 12/24/2002 |
| 6423699 | Combination therapies using benzimidazolones This invention relates to cyclic combination therapies and regimens utilizing substituted indoline derivative compounds which are antagonists of the progesterone receptor having the general structure: ##STR1## wherein: A is O, S, or NR4 ; B is ... | 07/23/2002 |
