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Assignee: Les Laboratories Servier


Location: Courbevoie Cedex, FR
No. of patents: 25

NumberTitleIssue Date
7534896Process for the synthesis of perindopril and its pharmaceutically acceptable salts
Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...
05/19/2009
74983304-oxo-4,6,7,8-tetrahydro-pyrrolo[1,2-a]pyrazine-6-carboxamide compounds
Compound of formula (I): wherein: represents 1-oxidopyridyl substituted by the remainder of the molecule in any one of the positions 2, 3 and 4,
03/03/2009
7470806Process for the synthesis of (7-methoxy-1-naphthyl) acetonitrile and its application in the synthesis of agomelatine
A process for the industrial synthesis of the compound of formula (I) Application in the synthesis of agomelatine. ...
12/30/2008
7459434Peptide interacting with anti-apoptotic proteins of the Bcl-2 family
The invention relates to the identification of a new peptide interacting with the anti-apoptotic proteins Bcl-2, Bcl-W and/or Bcl-XL, and also to screening methods allowing identification of modifiers of those interactions. ...
12/02/2008
7368580Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof
Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...
05/06/2008
7358395Crystalline form V of agomelatine, a process for its preparation and pharmaceutical compositions containing it
Crystalline form V of the compound of formula (I): characterised by its powder X-ray diffraction diagram. Medicinal products containing the same which are useful in the treatment of melatoninergic disorders. ...
04/15/2008
7358372Method for the synthesis of perindopril and the pharmaceutically acceptable salts thereof
Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...
04/15/2008
7323575Process for the synthesis of (2S)-indoline-2-carboxylic acid
Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts. ...
01/29/2008
7312213Substituted benzo[e][1,4]oxazino[3,2-g]isoindole compounds
A compound selected from those of formula (I): wherein: W1, with the carbon atoms to which it is bonded, represents phenyl or pyridyl, Z represents a...
12/25/2007
7265220Amino acid derivatives, method for production thereof and pharmaceutical compositions comprising said derivative
Compound of formula (I): wherein: R1 represents aryl, heteroaryl or alkyl which is optionally substituted, or a group of formula —(CO)—CR6R7NR8R9 ...
09/04/2007
7262191Benzothiadiazine compounds
The invention relates to compounds of formula (I): wherein: X represents oxygen or sulphur, R1 represents linear or branched (C1-C6
08/28/2007
7214805Process for the industrial synthesis of strontium ranelate and its hydrates
The process for the industrial The synthesis of strontium ranelate of formula (I): and its hydrates. ...
05/08/2007
7214689Isoquinoline compounds
The invention relatests compound of formula (I): wherein: n is 1, 2 or 3, A represents a group
05/08/2007
7208607Process for synthesis of perindopril and pharmaceutically acceptable salts thereof
Process for the synthesis of perindopril of formula (I): and pharmaceutically acceptable salts thereof. ...
04/24/2007
7202255Substituted [1,4] benzodioxino[2,3-e] isoindole derivatives, method for preparing and pharmaceutical compositions containing same
Compounds of formula (I): wherein: A is as defined in the description, Y represents a group selected from an oxygen atom and a methylene group,
04/10/2007
7196204Method for the synthesis of s-indoline-2-carboxylic acid and application thereof in the synthesis of perindopril
Process for the synthesis of (2S)-indoline-2-carboxylic acid of formula (I): Application in the synthesis of perindopril and its pharmaceutically acceptable salts. ...
03/27/2007
7166633Method for synthesising perindopril and the pharmaceutically acceptable salt thereof
Process for the synthesis of perindopril of formula (I): and pharmaceutically acceptable salts thereof. ...
01/23/2007
7151108[3,4-a:3,4-c]carbazole compounds
A compound selected from those of formula (I): wherein: W1 represents, together with carbon to which it is bonded, phenyl, pyridyl, Z represents a gr...
12/19/2006
7074920Process for the synthesis of 1,3-dihydro-2H-3-benzazepin-2-one compounds, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid
Process for the synthesis of compounds of formula (I): wherein R1 and R2, which may be the same or different, each represent a linear or branched (C1–C8)alkoxy group ...
07/11/2006
6992085Octahydro-2H-pyrido[1,2-a]pyrazine compounds
A compound selected from those of formula (I): wherein: Ra represents linear or branched (C1–C6)alkylene, X represents a group selected from W
01/31/2006
6872851Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them
The invention concerns compounds of formula (I): R—A—R′ wherein: A is as defined in the description; R represent, a group (V), wherein R′a and R″a are as defined in the description, or R forms with A a cyclic structure as defined in t...
03/29/2005
6846833Vitronectin receptor antagonist bicyclic compounds, preparation method and compositions containing same
Compounds of formula (1): wherein: G represents an optionally substituted phenyl or optionally substituted heterocycle, G1 and G2 being N or C, ...
01/25/2005
6716852Amino acid derivatives and use thereof as NEP, ACE and ECE inhibitors
The invention relates to compounds of formula (I): wherein 0≦n≦3, 0≦m≦6, R3 and R4 together form phenyl, B represents heteroaryl, R1 and R2...
04/06/2004
64517891-aza-2-alky-6-aryl-cycloalkanes
Compound of formula (I): ##STR1## wherein: n represents 0 or 1, R1 represents hydrogen, arylalkyl, alkyl, acyl, alkoxycarbonyl, arylalkoxycarbonyl or trifluoroacetyl, R2 represents alkyl, X represents oxygen, chlorine, OR3, SR
09/17/2002
6441165Process for the preparation of 11-amino-3-chloro-6, 11-dihydro-5, 5-dioxo-6-methyl-dibenzo[c,f][1,2]thiazepine and application to the synthesis of tianeptine
Process for the industrial synthesis of the compound of formula (I): ##STR1## and its addition salts. Application to the synthesis of tianeptine and its pharmaceutically acceptable salts....
08/27/2002
 
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