Assignee: Les Laboratoires Servier

Location: Courbevoie, FR
No. of patents: 45

Number	Title	Issue Date
7262189	Benzothiazine and benzothiadiazine derivatives, method for preparing same and pharmaceutical compositions containing same Compounds of formula (I): wherein: R1 represents aryl or heteroaryl, R2 represents hydrogen, halogen or hydroxy, X represents oxygen or sulphur, ...	08/28/2007
7253163	Benzothiazine and benzothiadiazine compounds Compounds of formula (I): wherein: R1 represents a heterocycle, R2 represents hydrogen, a halogen or hydroxy, A represents CR4R5 ...	08/07/2007
7183318	Substituted cyclic compounds, preparation method and pharmaceutical compositions containing them The invention concerns compounds of formula (1): R-A-R′ wherein: A is as defined in the description; R represent a group (V), (VI), (VII), or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R�...	02/27/2007
7182960	Pharmaceutical compositions for nasal delivery of oestradiol and norethisterone The present invention relates to a pharmaceutical composition for administration by the nasal route of 17-β-oestradiol and norethisterone. ...	02/27/2007
7183308	Metod for the synthesis of perindopril and the pharmaceutically acceptable salts thereof A process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...	02/27/2007
7179833	Method of synthesising perindopril and the pharmaceutically acceptable salts thereof Process for the synthesis of perindopril of formula (I): and its pharmaceutically acceptable salts. ...	02/20/2007
7176197	Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid Process for the synthesis of ivabradine of formula (I): addition salts with a pharmaceutically acceptable acid and hydrates thereof. α crystalline form of ivabradine hydrochloride. Medicinal produ...	02/13/2007
7161035	Substituted biphenyl derivatives, method for preparing same and pharmaceutical compositions containing same The invention relates to compounds of formula (I): wherein: B represents a hydrogen atom, a COOR group, a CONRR′ group, or a (C1–C6)alkyl group substit...	01/09/2007
7157485	Method for synthesizing derivatives of (2S,3AS,7AS)-1-[(S)-alanyl]-octahydro,-1H-indole-2-carboxylic acid and the use thereof for perindopril synthesis Process for the synthesis of compounds of formula (I): wherein R1 represents hydrogen, alkyl or benzyl and R2 represents a protecting group for the amine function. Application in the...	01/02/2007
7157484	Method for synthesissing (2s, 3as, 7as)-perhydroindole-2-carboxylic acid and the esters thereof and the use thereof for perindopril synthesis Process for the synthesis of compounds of formula (I): wherein R represents hydrogen or a protecting group. Application in the synthesis of perindopril and pharmaceutically acceptable salts thereof. ...	01/02/2007
7144891	Benzo[b ]pyrano[3,2- h ]acridin-7-one cinnamate compounds A compound selected from those of formula (I): wherein: X and Y represent a group selected from hydrogen, halogen, alkoxy, nitro, cyano, alkyl, alkenyl, polyhaloalkyl and —NR	12/05/2006
7126012	Substituted cyclic compounds The invention concerns compounds of formula (I): R-A-R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description; R�...	10/24/2006
7115752	Substituted cyclic compounds The invention concerns compounds of formula (I): R—A—R′ wherein: A is as defined in the description; R represents a group (V), (VI), (VII) or (VIII), where E, Q, R1, R2, R3, v and R4 are as defined in the description...	10/03/2006
7105683	Process for the industrial synthesis of the methyl diester of 5-amino-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates The process for the industrial the synthesis of the compound of formula (I): Application to the the synthesis of bivalent salts of ranelic acid and more especially strontium ranelate and its hydrates. ...	09/12/2006
7098220	Imidazopyridine derivatives, preparation method and pharmaceutical compositions containing same Compounds of formula (I): wherein: R1 represents hydrogen, halogen, alkyl, polyhaloalkyl, cyano, nitro, hydroxycarbonyl, alkoxycarbonyl, aminocarbonyl, alkylaminocarb...	08/29/2006
7091364	Process for the industrial synthesis of tetraesters of 5-[bis(carboxymethyl)amino]-3-carboxymethyl-4-cyano-2-thiophenecarboxylic acid, and application to the synthesis of bivalent salts of ranelic acid and their hydrates The process for the industrial synthesis of compounds of formula (I): wherein R and R′, which are the same or different, each represent linear or branched (C1–C6)alkyl. Applicati...	08/15/2006
7071221	Heterocyclic oxime compounds Compounds of formula (I): wherein: X represents oxygen or sulphur or a group CH2 or ...	07/04/2006
7064200	Process for the synthesis of 1,3,4,5-tetrahydro-2H-3-benzazepin-2-one compounds, and application in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid Process for the synthesis of compounds of formula (I): wherein R1 and R2, which may be the same or different, each represent a linear or branched (C1–C8)alkoxy group ...	06/20/2006
7060842	Method for synthesis of (2S, 3aS, 7aS)-1-{(S)-alanyl}-octahydro-1-indole-2-carboxylic acid derivatives and use for synthesis of perindopril Process for the industrial synthesis of the compounds of formula (I): wherein R1 represents a hydrogen atom or an alkyl or benzyl group, and R2 represents a group that protects the amino fun...	06/13/2006
7056929	Benzo[b]pyrano[3,2-h]acridin-7-one compounds A method for treating a living body afflicted with a cancer selected from lung and ovarian carcinoma, comprising the step of administering to the living animal body an amount of a compound selected from those of formula (I):	06/06/2006
7053108	Indoline compounds A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino...	05/30/2006
7026357	Diphenylurea compounds Compound of formula (I): and medicinal products containing the same are useful as dual α2/5-HT2c antagonist receptors. ...	04/11/2006
7008613	Quaternary ammonium compounds A compound of formula corresponding to either formula (Ia) or (Ib): wherein: M represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage, ...	03/07/2006
7001906	Pyrido-pyrido-pyrrolo pyrrolo-indole and pyrido-pyrrolo pyrrolo carbazole derivatives, method for the production thereof and pharmaceutical compositions containing said derivatives Compounds of formula (I): wherein: W1 and W2, together with the carbon atoms to which they are bonded, represent a phenyl group or a pyridyl group, and at least o...	02/21/2006
6998403	Benzoindoline compounds A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amin...	02/14/2006
6982350	Process for the synthesis of (1S)-4,5-dimethoxy-1-(methylaminomethyl)-benzocyclobutane and addition salts thereof, and to the application thereof in the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid Process for the synthesis of the compound of formula (I): Application in the synthesis of ivabradine, addition salts thereof with a pharmaceutically acceptable acid, and hydrates thereof. ...	01/03/2006
6919362	Heterocyclic derivatives, preparation method and pharmaceutical compositions containing same Compounds of formula (I): wherein: X represents an oxygen or a sulphur or CH2 or R1 and R2 rep...	07/19/2005
6894043	Benzothiadiazine derivatives, preparation method and pharmaceutical compositions containing same Compound selected from those of formula (I): wherein: X represents flourine, bromine, iodine or methyl, each of R1 and R2, which may be identica...	05/17/2005
6878746	Carbamate and thiocarbamate podophyllotoxin derivatives, preparation method and pharmaceutical compositions containing them A compound selected from these of formula (I): wherein: R1 represents hydrogen, alkyl, aryl, arylalkyl, heteroaryl, heteroarylalkyl, alkoxycarbonyl, aryloxycarbonyl, arylalkoxycarbonyl, heterocy...	04/12/2005
6875788	Imidazoline compounds Compounds of formula (I): wherein: R1 represents an optionally substituted heteroaryl group, R2 represents an optionally substituted cycloalkyl ...	04/05/2005
6835843	Method for synthesis of perindopril and its pharmaceutically acceptable salts The invention concerns a method for synthesis of perindopril of formula (I) and its pharmaceutically acceptable salts ...	12/28/2004
6818788	Method for synthesis of n-[(s)-1-carboxybutyl]-(s)-alanine esters and use in synthesis of perindopril Stereoselective process for the industrial synthesis of compounds of formula (I): wherein R represents linear or branched (C1-C6)alkyl. Application in the synthesis of perindopril and phar...	11/16/2004
6780868	Linear cyclic ureas Compounds of formula (I): wherein: V represents a single bond or a linear or branched (C1-C6)alkylene chain, M represents a single bond or a linear or branched (C1-C6	08/24/2004
6774259	Method for synthesis of n-[(s)]-1-carboxybutyl-(s)-alanine esters and use in synthesis of perindopril A stereoselective process for the industrial synthesis of compounds of formula (I): wherein R represents linear or branched (C1-C6)alkyl, and application in the synthesis of perindopril and p...	08/10/2004
6759421	Indoline compounds, a process for their preparation and pharmaceutical compositions containing them A compound of formula (I): wherein: R1 and R2 together form a benzo ring optionally substituted by halogen or by alkyl, alkoxy, cyano, nitro, hydroxy, amino, alkylamino, dialkylamino or trifl...	07/06/2004
6759406	Quaternary ammonium compounds Compounds of formula corresponding to either formula (Ia) or (Ib): wherein: M represents a molecule that can be used for the treatment or diagnosis of pathologies caused by attack on the cartilage, R1	07/06/2004
6747032	Pyrimidin-4-one compounds Compound of formula (I): wherein: R1, R2, R3 and R4, which may be the same or different, each represent a hydrogen atom, a halogen atom or a group selected from alkyl, a...	06/08/2004
6686360	N-benzylpiperazine compounds The present invention relates to a compound selected from those of formula (I): ##STR1## wherein: R1 represents alkyl, R2 represents hydroxy, alkoxy, or amino, n represents an integer from 1 to 12 inclusive, R3 represents: hydr...	02/03/2004
6541471	Benzenesulphonamide compounds A compound of formula (I): ##STR1## wherein: G represents a group such as: ##STR2## wherein R1 and R2 independently represent a hydrogen atom or an alkyl, cycloalkyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, heteroaryl or h...	04/01/2003
6495543	Polycyclic azaindole compounds The invention relates to compounds of formula (I): ##STR1## wherein: G1 represents an alkylene chain as defined in the description, A represents ##STR2## R2 and R3 represent hydrogen, alkyl, alkoxy or hydroxy or together f...	12/17/2002

«First «Previous1 2 Next»Last»

PatentStorm

Bizarre Patents

PatentStorm News

Assignee: Les Laboratoires Servier