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| Number | Title | Issue Date |
| 8143478 | Peptide transporting to chromoplasts in petals and method of constructing plant having yellowish petals by using the same It is an object of the present invention to provide a means of imparting a yellowish flower color to a plant having no or little yellowish flower color or enhancing the yellowish flower color in a plant. In accordance with the present invention, a method of p... | 03/27/2012 |
| 8075726 | Method for producing hermetically sealed container for beverage or food An object of the present invention is to provide a method for producing a hermetically sealed container, which method comprises conducting hermetic sealing of a container for beverage or food using a laser welding method, whereby the process speed of the sealing pro... | 12/13/2011 |
| 7972809 | Methylotrophic yeast producing mammalian type sugar chain This invention is to provide a process for producing a glycoprotein comprising a mammalian type sugar chain, characterized in that the process comprises introducing an α-1,2-mannosidase gene into a methylotrophic yeast having a mutation of a sugar chain biosynthesi... | 07/05/2011 |
| 7736590 | Method for measuring oxygen amount in hermetically sealed container and piercing device for hermetically sealed container used therefore A method to efficiently measure the oxygen content of both the headspace and fluid within a hermetically sealed container. A container is pierced using a hollow needle with the interior space sealed from the outside and the tip of said hollow needle removed, and the... | 06/15/2010 |
| 7713717 | Method of preparing yeast for fermentation test A method of preparing a yeast usable in a fermentation test for evaluating malt on the laboratory scale whereby more reproducible test data can be obtained regardless of the operation conditions of a plant, etc.; and a medium to be used therein. A yeast for the ferm... | 05/11/2010 |
| 7638298 | Method for detecting mutation and a method for inducing mutation A novel plant transposon that induces bud mutation, transposase thereof, and a method for efficiently inducing bud mutation by improvement in the transposition efficiency are provided. A novel transposon having terminal inverted repeat sequences (SEQ ID NO: 1 and SE... | 12/29/2009 |
| 7592005 | Monoclonal antibody A monoclonal antibody or a functional fragment thereof that binds to a human BST2 antigen existing on the cell surface and can be localized through internalization into the cell, a complex comprising the monoclonal antibody or a functional fragment thereof and a the... | 09/22/2009 |
| 7553956 | Polynucleotide probe and primer for detecting beer-clouding lactic acid bacteria and method of detecting beer-clouding lactic acid bacteria An object of the present invention is to provide probes and primers for detecting beer-spoilage lactic acid bacteria with accuracy. The probes and primers for detecting beer-spoilage lactic acid bacteria according to the present invention each comprises a nucleotide... | 06/30/2009 |
| 7541037 | Film coating agent The present invention provides a coating agent, wherein an oxygen-barrier property enhancer, which is one or more of glucose, mannose, maltose, trehalose, fructose, raffinose, arabinose, nigerooligosaccharide, lactose, D-glucono-1,5-lactone, arginine hydrochloride, ... | 06/02/2009 |
| 7531346 | Decolorized yeast cell wall fraction The yeast cell wall fraction comprising cell residues obtained by removing internal soluble components from enzyme-treated yeast, or cell residues obtained by treating the cell residues with acid solution and removing the acid solution-soluble components. By decolor... | 05/12/2009 |
| 7414170 | Transgenic bovines capable of human antibody production The invention features novel methods for the production of large quantities of xenogenous antibodies, such as human antibodies. Preferably, this result is effected by inactivation of IgM heavy chain expression and, optionally, by inactivation of Ig light chain expre... | 08/19/2008 |
| 7385048 | Promoters and utilization thereof The present invention relates to improved promoters and utilization thereof, in particular to promoters which are improved so as not to undergo methylation in the course of constructing transformants, and utilization thereof. According to the present invention, the ... | 06/10/2008 |
| 7320880 | Polypeptide having an activity to support proliferation or survival of hematopoietic stem cell and hematopoietic progenitor cell, and DNA coding for the same A gene encoding a polypeptide having an activity to support proliferation or survival of hematopoietic stem cells or hematopoietic progenitor cells is isolated by comparing expressed genes between cells which support proliferation or survival of hematopoietic stem c... | 01/22/2008 |
| 7319141 | Stem cell growth factor-like polypeptides The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from c... | 01/15/2008 |
| 7282219 | Powdery preparation for transmucosal administration containing a polymeric form of drug and exhibiting improved storage stability A powdery preparation for transmucosal administration comprising a medicine of high molecular weight, a cationic polymer and, as needed, a viscous polymer, further comprising an effective amount of a basic amino acid. The powdery preparation for transmucosal adminis... | 10/16/2007 |
| 7262278 | Anti-HLA-DR antibody This invention provides an anti-HLA-DR monoclonal antibody. This invention relates to an antibody binding to HLA-DR or a functional fragment thereof having (a) life-extending effects in nonhuman animals bearing HLA-DR-expressing cancer cells and (b) activity of supp... | 08/28/2007 |
| 7247327 | Process for producing wort for fermented malt drinks The present invention provides a process for producing a wort with reduced content of a stale flavor-causing substance for the production of fermented malt beverages such as beer and the like in which generation of a stale flavor is suppressed, and it also provides ... | 07/24/2007 |
| 7238355 | Coated material and process for producing the coated material A coated material and a process for producing the coated material which includes providing a coating agent comprising yeast cell wall fractions, as a primary constituent, consisting of cell residue of yeast which has been treated with enzymes, optionally subsequentl... | 07/03/2007 |
| 7217722 | Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same An objective of the present invention is to provide compounds having Rho kinase inhibitory activity. The compounds according to the present invention are those represented by formula (I) or pharmaceutically acceptable salts or solvates thereof: Het—X—Z... | 05/15/2007 |
| 7195915 | Vectors for animal cells and use thereof Protein synthesis inhibitor resistance genes (typified by a cycloheximide resistance gene) are capable of imparting resistance to a protein synthesis inhibitor (typified by cycloheximide) to animal cells sensitive to the inhibitor. The genes have a sequence mutated ... | 03/27/2007 |
| 7193064 | Anti-CD40 monoclonal antibody An antibody or a functional fragment thereof, acting agonistically or antagonistically on CD40. ... | 03/20/2007 |
| 7115420 | Promoters and utilization thereof The present invention relates to improved promoters and utilization thereof, in particular to promoters which are improved so as not to undergo methylation in the course of constructing transformants, and utilization thereof. According to the present invention, the ... | 10/03/2006 |
| 7115717 | Anti-TRAIL-R antibodies Anti-TRAIL-R1 and R2 antibodies or functional fragments thereof, having at least one property selected from the following (a) to (c) of: (a) having activity to induce apoptosis in carcinoma cells expressing TRAIL-R1 and/or TRAIL-R2; (b) not having effe... | 10/03/2006 |
| 7074983 | Transgenic bovine comprising human immunoglobulin loci and producing human immunoglobulin The present invention relates to the production of a transgenic bovine which comprises a genetic modification that results in inactivation and loss of expression of its endogenous antibodies, and the expression of xenogenous antibodies, preferably human antibodies. ... | 07/11/2006 |
| 7064194 | Vectors for animal cells and utilization thereof Protein synthesis inhibitor resistance genes (typified by a cycloheximide resistance gene) are capable of imparting resistance to a protein synthesis inhibitor (typified by cycloheximide) to animal cells sensitive to the inhibitor. The genes have a sequence mutated ... | 06/20/2006 |
| 6964975 | Isoxazole and thiazole compounds and use thereof as medicine The present invention relates to novel isoxazole and thiazole compounds having an excellent lysophosphatidic acid (LPA) receptor antagonistic activity represented by general formula [1] or salts thereof: wherein R1 and... | 11/15/2005 |
| 6919082 | Pharmacological composition containing yeast cell wall fraction The present invention provides a pharmacological composition as a composition as a raw material capable of preventing or treating the symptoms of inflammatory bowel diseases such as ulcerative colitis, constipation, allergic diseases such as atopic dermatitis, and s... | 07/19/2005 |
| 6890531 | Neuronal growth factor galectin-1 This invention relates to a remedy for neuropathy, such as nerve injury, nerve degeneration, and hypofunction upon nerve grafting, which contains as the active ingredient galectin-1 having an amino acid sequence represented by SEQ ID NO:1 or its derivative; a protei... | 05/10/2005 |
| 6875884 | Urea derivatives as inhibitors for CCR-3 receptor Urea and thiourea derivatives inhibit cell function of the chemokine receptor CCR-3. These compounds offer an effective means for treating a range of diseases thought to be mediated by the CCR-3 receptor. A variety of useful urea and thiourea derivatives can be synt... | 04/05/2005 |
| 6843842 | Glass coating agent and method for coating glass material using the same A glass coating agent is provided which is adapted for application onto the surface of a glass substrate and, upon heating, forms a metal oxide layer. The glass coating agent comprises a metallic compound represented by formula (I): R1k-m | 01/18/2005 |
| 6824973 | Method of promoting stem cell proliferation or survival by contacting a cell with a stem cell factor-like polypeptide The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human stem cell growth factor-like protein. These polynucleotides comprise nucleic acid sequences isolated from c... | 11/30/2004 |
| 6821987 | Quinoline derivatives and quinazoline derivatives having azolyl group An object of the present invention is to provide compounds having potent antitumor activity. The compounds according to the present invention are compounds represented by formula (I) or pharmaceutically acceptable salts or solvates thereof: ... | 11/23/2004 |
| 6821749 | Methods of producing carotenoids using DNA molecules encoding isopentenyl pyrophosphate isomerase The production of carotenoid is accomplished using a DNA molecule that encodes a polypeptide as obtained from Haematococcus pluvialis, Phaffia rhodozyma, or Saccharomyces cerevisiae, having isopentonyl pyrophosphate (IPP) isomerase activity, or DNA mol... | 11/23/2004 |
| 6815191 | Endo-β-N-acetylglucosaminidase gene An endo-β-N-acetylglucosaminidase gene encoding the following protein (a) or (b): (a) a protein comprising the amino acid sequence represented by SEQ ID NO: 3; and (b) a protein comprising an amino acid sequence derived from the amino acid sequence represented by S... | 11/09/2004 |
| 6805931 | Plastic container coated with carbon film A plastic container has a diamond like carbon film 20b formed on the inner surface of the container 20 made of plastic material 20a. The thickness of the diamond like carbon film 20b is within a range from 0.05 to 5 Î... | 10/19/2004 |
| 6777092 | Coating and material for forming vitreous coating film, method of coating with the same, and coater The present invention relates to a a glassy-film forming coating agent, a method of coating a substrate with the a glassy-film forming coating agent, a bottle coated with the glassy-film forming coating agent, and a coating system for coating a substrate with the gl... | 08/17/2004 |
| 6750255 | Calcium receptor-active compounds A novel calcium receptor active compound having the formula is provided: Ar1—[CR1R2]p—X—[CR3R4]q—[CR5R6]—NR7—[CR8R | 06/15/2004 |
| 6747010 | NKT cell-activating agents containing α-glycosylceramides An objective of the present invention is to provide NKT cell-activating agents, therapeutic agents for autoimmune diseases (for example, systemic lupus erythematosus, systemic sclerosis, ulcerative colitis, encephalomyelitis, multiple sclerosis and human type I diab... | 06/08/2004 |
| 6673904 | Stem cell growth factor-like polypeptides The invention provides novel polynucleotides and polypeptides encoded by such polynucleotides and mutants or variants thereof that correspond to a novel human and mouse secreted stem cell growth factor-like polypeptide. These polynucleotides comprise nucl... | 01/06/2004 |
| 6632976 | Chimeric mice that are produced by microcell mediated chromosome transfer and that retain a human antibody gene A chimeric, non-human animal can be produced by a method that entails providing a microcell that contains one or more foreign chromosomes or fragment(s) thereof and then fusing the microcell with a pluripotent cell, thereby introducing the foreign chromos... | 10/14/2003 |
