...that Thomas Edison's patent application on his phonograph was approved by the Patent Office in just seven weeks? In contrast, it took Gordon Gould, the inventor of the laser, 30 years to obtain his patent -- finally awarded in 1988!
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| Number | Title | Issue Date |
| 8184814 | Audio signal processing method and system The invention makes use of impulse responses of the performance venue to process a recording or other signal so as to emulate that recording having being recorded in the performance venue. In particular, by measuring or calculating the impulse responses of a perform... | 05/22/2012 |
| 8088586 | Method of producing a body fluid sample depleted of anti-MHC antibodies The invention provides a method of depleting anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and removing at least the recombinant MHC ... | 01/03/2012 |
| 7888030 | Biomarkers The present invention provides circulating biomarkers for conditions associated with metabolic syndrome, including diabetes mellitus, hypertension and congestive heart failure. The biomarkers include plasma DNA, neuron-specific enolase, 11β-hydroxysteroid dehydroge... | 02/15/2011 |
| 7596385 | Method of discovering multi-mode mobile terminals A method of discovering multi-mode mobile terminals (13) in a heterogeneous network environment, each multi-mode mobile terminal (13) having at least one interface for sending packet data to and/or receiving packet data from a home radio communication ... | 09/29/2009 |
| 7425419 | Diagnosis of pre-eclampsia The present invention relates to a method of predicting pre-eclampsia (PE). The present invention also relates to a diagnostic kit for performing a method of predicting PE. In particular, the method determining the level of two or more markers selected from placenta... | 09/16/2008 |
| 7408031 | Peptide epitopes recognized by disease promoting CD4+ T lymphocytes The invention provides methods for identifying peptide epitopes that activate CD4+ T cells involved in the pathogenesis of diseases, e.g., autoimmune diseases, susceptibility to which is determined by expression of particular class II MHC genes. The invention includ... | 08/05/2008 |
| 7408029 | Peptide epitopes recognized by disease promoting CD4+ T lymphocytes The invention provides methods for identifying peptide epitopes that activate CD4+ T cells involved in the pathogenesis of diseases, e.g., autoimmune diseases, susceptibility to which is determined by expression of particular class II MHC genes. The invention includ... | 08/05/2008 |
| 7314844 | Process for the cyanation aldehydes A process for cyanating an aldehyde is provided. The process comprises reacting the aldehyde with: i) a cyanide source which does not comprise a Si—CN bond or a C—(C═O)—CN moiety; and ii) a substrate susceptible to nucleophilic atta... | 01/01/2008 |
| 7196061 | Compounds that modulate neuronal growth and their uses Cyclic peptides and peptidomimetics are provided that bind to and/or modulate activities associated with Trk receptors, including processes associated with the growth and repair of the central nervous system (e.g., neuronal growth and survival, axonal growth, neurit... | 03/27/2007 |
| 7173108 | Peptide epitopes recognized by disease promoting CD4+ T lymphocytes The invention provides methods for identifying peptide epitopes that activate CD4+ T cells involved in the pathogenesis of diseases, e.g., autoimmune diseases, susceptibility to which is determined by expression of particular class II MHC genes. The invention includ... | 02/06/2007 |
| 7049292 | Therapeutically effective peptides related to preproinsulin A peptide having a sequence comprising or consisting of QPLALEGSLQK. ... | 05/23/2006 |
| 7040960 | Use of bioactive glass for cutting bioactive glasses The present invention relates to a method of cutting a bioactive glass object which comprises contacting the bioactive glass object with bioactive glass particles delivered using an air abrasion system. ... | 05/09/2006 |
| 7031720 | Pre-emptive bandwidth allocation by dynamic positioning In mobile communication and radio systems there is a pre-emptive bandwidth allocation by dynamic partitioning the total spectrum available to allow mobile user groups with high priority services to access greater amounts of bandwidth than mobile user groups with low... | 04/18/2006 |
| 6991810 | Product from starfish The invention relates to a product capable of having one or more properties sected from: anti-fouling properties, anti-adhesive properties, anti-inflammatory properties, and wherein said product is obtainable from starfish. ... | 01/31/2006 |
| 6916653 | Ribozymal nucleic acid A vector system which can be incorporated in liposomes, comprising at least one DNA vector, the vector or vectors containing a target-cleaving hammerhead ribozymal DNA sequence under control of a promoter effective in human cells and which, upon transcription to RNA... | 07/12/2005 |
| 6897332 | Process for the cyanation of aldehydes A process for cyanating an aldehyde is provided. The process comprises reacting the aldehyde with: i) a cyanide source which does not comprise a Si—CN bond or a C—(C═O)—CN moiety; and ii) a substrate susceptible to nucleophilic atta... | 05/24/2005 |
| 6584150 | Dual direction channel estimator In the Global System for Mobile Communication (GSM), an improvement in estimating the channel impulse response (CIR) is obtained by starting up two channel estimators using the midamble and obtaining channel estimations with split burst. The two estimatio... | 06/24/2003 |
| 6562943 | Peptide epitopes recognized by disease promoting CD4+ T lymphocytes The invention provides methods for identifying peptide epitopes that activate CD4+ T cells involved in the pathogenesis of diseases, e.g., autoimmune diseases, susceptibility to which is determined by expression of particular class II MHC genes. The inven... | 05/13/2003 |
| 6342225 | Pharmaceutical active conjugates The invention provides an analogue of a pharmaceutical active whose molecular weight is less than 25,000 Daltons, the analogue comprising a pharmaceutical active whose molecular weight is less than 25,000 Daltons covalently linked to a pendant molecular g... | 01/29/2002 |
| 6063761 | Hepatoselective pharmaceutical actives The invention provides an analogue of a pharmaceutical active whose molecular weight is less than 25,000 Daltons, the analogue comprising a pharmaceutical active whose molecular weight is less than 25,000 Daltons covalently linked to a pendant molecular g... | 05/16/2000 |
| 5994084 | Models of Alzheimer's disease Transgenic cell and animal models for Alzheimer's disease are described. Cells of the animals and the cell models themselves comprise a recombinant DNA construct comprising a control sequence and, under the control of the control sequence, a DNA sequence ... | 11/30/1999 |
| 5975076 | Dry powder inhalers A dry powder inhaler is provided which comprises a reservoir of medicament powder, a dispensing chamber for receiving a charge of powder to be dispensed having a floor upon which the powder charge lies prior to inhalation, an inlet passage having at its o... | 11/02/1999 |
| 5708161 | Nucleoside phosphorothioate derivatives, synthesis and use thereof Inter alia, a process for the production of a nucleoside phosphorothioate derivative corresponding to the following general formula (I): ##STR1## characterized in that it comprises reacting a salt of a nucleoside H-phosphonate corresponding to the fo... | 01/13/1998 |
| 5625046 | Hydroxyl projecting groups for organic synthesis 1-N-substituted-4-alkoxy-piperidin-4-yl group is disclosed as a protecting reagent for the 2'-hydroxyl of oligo- or poly-ribonuleotides. This protecting group is applicable to the protection of the 2'-hydroxyl group during oligo- or poly-ribonucleotide sy... | 04/29/1997 |
| 5564115 | Neural network architecture with connection pointers A neural network unit is described which has a plurality of neurons. The network comprises a RAM, which provides a plurality of storage locations for each of the neurons and an integrated circuit. The integrated circuit including means for defining an alg... | 10/08/1996 |
| 5561110 | Method for the treatment of the complications and pathology of diabetes The present invention provides a method for the treatment of the complications and pathology of diabetes. The method involves the administration to a diabetic subject of a composition comprising a compound selected from the group consisting of (ଲ-Al... | 10/01/1996 |
| 5553197 | Devices for use in neural processing A device for use in neural processing comprises a plurality of probabilistic RAMs (pRAMs). The output of the pRAMs are connected in common to means for accumulating their output signals and for decaying the result of the accumulation. A thresholding circu... | 09/03/1996 |
| 5475795 | Neural processing devices for handling real-valued inputs A device for use in a neural processing network. The network includes a memory having a plurality of storage locations each having stored a number representing a probability. Each storage location is selectively addressible to cause the contents of the lo... | 12/12/1995 |
| 5436331 | Protection of hydroxy function with 1-N-aryl-4-alkoxy-piperidin-4-yl A process for protecting the 2'-hydroxyl of a nucleoside, which can then be used in the chemical synthesis of polyribonucleotides, comprising the reacting of a protected nucleoside of formula I ##STR1## wherein B is a nucleoside heterocyclic base and... | 07/25/1995 |
| 5221606 | Reagent and kit for enzyme assay comprising a substrate consonant with given enzyme to be assayed This invention relates to enzyme assays and substrates for use in such assays. The presence or absence of certain enzymes in vivo is a useful indicator of illness or deficiency in the organisms concerned. Enzymes are also useful in monitoring microbial gr... | 06/22/1993 |
| 5175798 | Digital artificial neuron based on a probabilistic ram A neuron for use in a neural processing network, comprises a memory having a plurality of storage locations at each of which a number representing a probability is stored, each of the storage locations being selectively addressable to cause the contents o... | 12/29/1992 |
| 4652501 | Operation of microbial fuel cells In operation of a microbial fuel cell it has been found that improved efficiency results if the microbes are kept `hungry`, i.e. the cell is run under conditions of fuel supply and load such that electrical output is dependent on fuel concentration, rathe... | 03/24/1987 |