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Assignee: Kikkoman Corporation


Location: Noda, JP
No. of patents: 89

1      
NumberTitleIssue Date
7189548Modified sarcosine oxidases, genes and recombinant DNAs thereof, and methods for preparing the same
(1) A modified sarcosine oxidase with improved stability in the acidic range compared to a wild-type sarcosine oxidase. (2) A sarcosine oxidase gene encoding a modified sarcosine oxidase of the following (a), (b), or (c): (a) prote...
03/13/2007
7132253Modified sarcosine oxidases, modified sarcosine oxidase genes, and methods for preparing the modified sarcosine oxidases
A modified sarcosine oxidase having a lowered activity for N-ethylglycine. Such a modified oxidase may have the following physicochemical properties: (a) action: hydrolyzes 1 mol of sarcosine to produce 1 mol of glycine and 1 mol o...
11/07/2006
7101694Genes encoding proteins capable of regenerating luciferin, recombinant DNA and process for producing protein capable of regenerating luciferin
The present invention relates to: an isolated or synthesized gene, which encodes a protein comprising the amino acid sequence represented by SEQ ID NO: 2, an isolated or synthesized gene, which encodes a protein comprising an amino acid sequence compri...
09/05/2006
7091017Fructosyl amino acid oxidase
The present invention provides a novel fructosyl amino acid oxidase that is excellent in thermal stability. Moreover, the present invention provides a fructosyl amino acid oxidase gene encoding the novel fructosyl amino acid oxidase, a recombinant DNA in which the g...
08/15/2006
7070948Method for assaying glycated protein
Based on a principle that is different to that of a conventional enzymatic method, the present invention provides a novel method for assaying a glycated protein by a simple procedure, within a short period of time, and with high accuracy, and a reagent kit for assay...
07/04/2006
7056543Method of brewing soy sauce
According to the present invention, there is reliably provided a soy sauce having desired ethanol and lactic acid concentrations and a mellow flavor. A method of brewing soy sauce which comprises mixing soy sauce koji into a salt water to prepare a soy sauce moromi ...
06/06/2006
7049113Gene encoding protein capable of regenerating luciferin, recombinant DNA and process for producing protein capable of regenerating luciferin
The present invention relates to: an isolated or synthesized gene, which encodes a protein comprising the amino acid sequence represented by SEQ ID NO: 2, an isolated or synthesized gene, which encodes a protein co...
05/23/2006
7018823Fructosyl peptide oxidase
The present invention has an object of providing a novel fructosyl peptide oxidase having superior physicochemical properties such as stability that is useful as an enzyme for clinical diagnosis, and an object of providing a method for producing the fructosyl peptid...
03/28/2006
6951750Prolidase and its gene and method for producing prolidase
Provided are a protein comprising the amino acid sequence as shown in SEQ ID NO: 2 and having prolidase activities, a prolidase gene coding for the protein, a prolidase gene comprising the nucleotide sequence as shown in SEQ ID NO: 1, recombinant DNA having the gene...
10/04/2005
6919195Glutaminase, glutaminase gene, novel recombinant DNA, and process for manufacturing glutaminase
Glutaminase which comprises (a) a protein comprising an amino acid sequence shown in SEQ ID NO: 2, or (b) a protein which comprises an amino acid sequence having deletion, substitution, or addition of one or plurality of amino acids relative to the amino acid sequen...
07/19/2005
6838270Gene encoding protein capable of regenerating luciferin, novel recombinant DNA, and process for producing protein capable of regenerating luciferin
A gene encoding a protein which is capable of regenerating luciferin by acting on oxyluciferin and D-cysteine and thus regenerating luciferin; the above gene originating in a luminous organism; a protein encoded by the above gene; and a process for producing a prote...
01/04/2005
6812012Luciferase and methods for assaying intracellular ATP by using the same
The present invention relates to luciferase having resistance to a surfactant and a method for measuring intracellular ATP which is characterized in that the luciferase having resistance to a surfactant is used in this method comprising the steps of: a first step wh...
11/02/2004
6596696Malto-oligosaccharide derivatives and uses thereof
Maltoligosaccharide derivatives represented by the general formula: ##STR1## wherein n is an integer of 0 to 3 and X is a hydrogen atom or a hydrophobic group) or their hydrates or physiologically acceptable salts, and an ଱-amylase inhibitor and a p...
07/22/2003
6569637Diagnostic reagents for renal function disorders and method for analyzing urine samples
The present invention aims at providing a reagent and a method for simply, rapidly, and accurately diagnosing renal dysfunction. According to the present invention, free ATP in a urine sample from a patient suffering from renal dysfunction is determined by a b...
05/27/2003
6531176Method and apparatus for producing tofu
A method for producing tofu is described which includes the step of detecting the concentration of a coagulant in soybean milk. The coagulant concentration is detected by a coagulant concentration detector disposed downstream of a stirring apparatus in a ...
03/11/2003
6444239Process for producing isoflavone aglycone-containing composition
An isoflavone aglycone-containing composition having genistein as a main aglycone is produced by a process comprising allowing a protease and ଲ-glucosidase to act on a soy protein raw material, an extract of a soy protein raw material or a by-produc...
09/03/2002
6376208Method and reagent for quantitating D-cysteine
The present invention relates to a method and a reagent for quantitating D-cysteine in a convenient and highly-sensitive manner. The present invention provides a method for quantitating D-cysteine in a sample, comprising the steps of: (a) reacting D-cysteine w...
04/23/2002
6329189Enzyme producing tartaric acid ether compound and process for producing tartaric acid ether compounds using this enzyme
Disclosed in this invention are a novel enzyme producing tartaric acid ether compound which catalyzes a reaction of producing a tartaric acid ether compound in which the phenolic hydroxyl group(s) of a flavonoid or its analogous compound having at least o...
12/11/2001
6272980Apparatus for producing tofu
A method for producing tofu is disclosed which includes the step of detecting the concentration of a coagulant in soybean milk. The coagulant concentration is detected by a coagulant concentration detector disposed downstream of a stirring apparatus in a ...
08/14/2001
6228626Sarcosine oxidase and process for producing the same
This invention relates to sarcosine oxidase having the following physico-chemical properties: (a) action: oxidatively hydrolyzing 1 mole sarcosine to give 1 mole glycine, 1 mole formaldehyde, and 1 mole hydrogen peroxide; (b) substrate specificity: specif...
05/08/2001
6200767ATP eliminator and the process for determining biological cells
The present invention provides a process for eliminating effectively ATP in a sample, using adenosine phosphate deaminase alone or in combination with at least one enzyme from the group consisting of apyrase, alkaline phosphatase, acid phosphatase, hexoki...
03/13/2001
6139899Soybean milk
Soybean milk contains malonylisoflavone glycosides in a ratio of 70% or higher to the total isoflavone compounds in the soybean milk....
10/31/2000
6127157Coating material
The present invention provides a coating suitable for coating woods, and the coating is obtained by dissolving proanthocyanidine into water or a water-containing alcohol....
10/03/2000
6120830Process for producing tofu
A process for producing tofu comprising primarily heating soybean milk containing a coagulant, packing the soybean milk into a container, and secondarily heating the soybean milk to coagulate....
09/19/2000
6074859Mutant-type bioluminescent protein, and process for producing the mutant-type bioluminescent protein
According to the present invention, there can be provided a bioluminescent protein, luciferase excellent in thermostability etc. and with high catalytic efficiency....
06/13/2000
6054150Method for producing seasoning liquids
Method for producing, in a short time period, a soy sauce seasoning liquid having a high nitrogen content by efficient utilization of vital gluten upon its addition to soy sauce koji and brine wherein the gluten is added to an enzymatically hydrolyzed mix...
04/25/2000
6051234Health diet for preventing diseases caused by life-habit
A health diet for preventing life-habit diseases (adult diseases) is provided. The health diet is prepared by directly encapsulating or tableting an organic solvent extract of soy sauce cakes or an aqueous alkali extract of a soy sauce oil, or blending th...
04/18/2000
5942427N-acetylmannosamine dehydrogenase gene and novel recombinant DNA as well as a method for production of N-acetylmannosamine dehydrogenase
N-acetylmannosamine dehydrogenase gene derived from a microorganism belonging to the genus Flavobacterium, e.g., Flavobacterium sp. No. 141-8 strain and defined by a specific restriction enzyme map which encodes 271 amino acid sequence. Using the recombin...
08/24/1999
5891702ATP eliminator and the process for determining biological cells
The present invention provides a process for eliminating effectively ATP in a sample, using adenosine phosphate deaminase alone or in combination with at least one enzyme selected from the group consisting of apyrase, alkaline phosphatase, acid phosphatas...
04/06/1999
5891659Bioluminescent adenosine phosphate ester assay and reagent
There is provided a bioluminescence reagent comprising at least pyruvate orthophosphate dikinase, phosphoenolpyruvic acid, pyrophosphoric acid, magnesium ion or another metallic ions, luciferin and luciferase, which reagent is such that the amount of lumi...
04/06/1999
5869115Process for producing seasoning
A process for producing a seasoning having high nitrogen concentration by hydrolyzing a proteinaceous material with enzyme, characterized in that common salt is added to the decomposed Moromi or the Moromi temperature is lowered, then the Moromi is allowe...
02/09/1999
5843746Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method
The present invention relates to biotinated firefly luciferase comprising a biotinated peptide and firefly luciferase linked therein, biotinated firefly luciferase having a specific amino acid sequence, a biotinated firefly luciferase gene comprising a ge...
12/01/1998
5814359Salt solution for producing soy sauce and process for producing soy sauce
A soy sauce is produced by mixing a salt solution having a hard component concentration of not more than 20 ppm as calcium with a soy sauce koji, and subjecting the mixture to fermentation and ageing and then compressing it to obtain a crude soy sauce, an...
09/29/1998
5814465Biotinated firefly luciferase, a gene for biotinated firefly luciferase, a recombinant DNA, a process for producing biotinated luciferase and a bioluminescent analysis method
The present invention relates to biotinated firefly luciferase comprising a biotinated peptide and firefly luciferase linked therein, biotinated firefly luciferase having a specific amino acid sequence, a biotinated firefly luciferase gene comprising a ge...
09/29/1998
5814494Process for improving the property of proanthocyanidins and for preparing an improved proanthocyanidin product
The present invention is directed to a process for improving the property of proanthocyanidins comprising contacting the proanthocyanidin containing solution with tannase and a process for increasing the yield of proanthocyanidins comprising contacting th...
09/29/1998
5814504Protein involved in regenerating firefly luciferin
A purified protein having a molecular weight of 40 kD by SDS-PAGE that produces firefly luciferin when combined with D-cysteine and firefly oxyluciferin and isolated from firefly species is provided, as well as methods of making and using the protein for ...
09/29/1998
5804597Agent for the prevention or treatment of cataracts
An agent for the prevention or treatment of cataracts comprising a proanthocyanidin oligomer is provided. The oral administration or application to the eyes of the agent of the invention produces a sufficient preventive or therapeutic effect against catar...
09/08/1998
5801036Mutant uricase, a mutant uricase gene, a novel recombinant DNA, and a process for producing mutant uricase
The present invention relates to mutant uricase containing the amino acid sequence of wild-type uricase shown in SEQ ID NO:1 wherein the 165-170th amino acids contain a mutated amino acid sequence, a mutant uricase gene coding for said uricase, a recombin...
09/01/1998
5789581Process for obtaining malonyl isoflavone glycosides and obtaining isoflavone glycosides or isoflavone aglycons from malonyl isoflavone glycosides
A malonylisoflavone glycoside present in soybean is obtained efficiently. In addition, the corresponding isoflavone glycoside and aglycone are obtained from the malonylisoflavone glycoside. An aqueous extract of soybean is adsorbed on an adsorbent, and el...
08/04/1998
5773262Process for the preparation of proanthocyanidins
The present invention aims at enhancing purity of the proanthocyanidin extracts by acting yeast to the proanthocyanidin extracts for fermenting them to thereby assimilate the impurities such as saccharides with yeast to reduce them....
06/30/1998
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