British merchant Peter Durand invented the tin can in 1810.
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| Number | Title | Issue Date |
| 8124129 | Crystalline form of the compound A-348441 There is provided a hemihydrate of (3β,5β,7α,12α)-7,12-dihydroxy-3-{2-[{4-[17β-hydroxy-3-oxo-17α-prop-1-ynylestra-4,9-dien-11β-yl]phenyl}(methyl)amino]ethoxy}cholan-24-oic acid in a crystalline form which is characterised by an X-ray diffraction pattern havin... | 02/28/2012 |
| 7956214 | Process for the preparation of aniline-derived thyroid receptor ligands Provided are processes for the synthesis of aniline derivatives, specifically certain aniline derivatives which have activity as thyroid receptor ligands. ... | 06/07/2011 |
| 7521439 | Glucocorticoid receptor ligands for the treatment of metabolic disorders This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in the regulation of metabolism, especially lowering serum glucose levels, insulin... | 04/21/2009 |
| 7342127 | Substituted anilide ligands for the thyroid receptor Novel thyroid receptor ligands are provided having the general formula I wherein X, R1, R2, R3, R4, R5, R6, R7,... | 03/11/2008 |
| 7319163 | Thyroid receptor antagonists for the treatment of cardiac and metabolic disorders This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac arrhythmias, thyrotoxicosis and subclinical hyperthyrodism. ... | 01/15/2008 |
| 7319096 | Thyroid hormone receptor antagonists for cardiac and metabolic disorders II This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism... | 01/15/2008 |
| 7288571 | Thyroid receptor ligands and method II New thyroid receptor ligands are provided which have general formula (I) in which: n is an integer from 0 to 4; R1 is halogen, trifluoromethyl, or alkyl of 1 to 6 carbons or cycloalkyl of 3 to 7 carbons; R2 and R3 are the same or dif... | 10/30/2007 |
| 7279593 | Prime ring substituted thyroid receptor antagonists for the treatment of cardiac and metabolic disorders This invention relates to novel compounds which are thyroid receptor ligands, preferably antagonists, and to methods for using such compounds in the treatment of cardiac and metabolic disorders, such as cardiac arrhythmias, thyrotoxicosis, subclinical hyperthyrodism... | 10/09/2007 |
| 7220752 | Compounds active at the glucocorticoid receptor II This invention relates to novel compounds that are liver selective glucocorticoid receptor antagonists, to methods of preparing such compounds, and to methods for using such compounds in therapy and in the regulation of metabolism, especially lowering blood glucose ... | 05/22/2007 |
| 7199265 | Thyroid receptor ligands, pharmaceutical compositions comprising them and their use in the treatment of disorders influenced by thyroid hormones This invention relates to compounds of the formula (I) which are thyroid receptor ligands, and are preferably selective for the thyroid hormone receptor β, to methods of preparing such compounds and to methods for using such compounds such as in the regulation of m... | 04/03/2007 |
| 6525188 | Nuclear retinoic acid co-receptor This invention provides an isolated receptor having the amino acid sequence of FIG. 1 (SEQ ID NO:2) or substantially the same amino acid sequence as the amino acid sequence shown in FIG. 1 (SEQ ID NO:2) or an amino acid sequence functionally similar to th... | 02/25/2003 |