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| Number | Title | Issue Date |
| 5712283 | Method of inhibiting hyperglycemia and pharmaceutical composition for use therein A method of using moxonidine or a physiologically acceptable acid addition salt thereof for the treatment and/or prophylaxis of hyperglycaemia, and pharmaceutical compositions for use therein.... | 01/27/1998 |
| 5679699 | (Phenylalkylaminoalkyloxy) -heteroaryl-compounds, processes and intermediates for their production and pharmaceutical compositions containing them 3-(Phenylalkylaminoalkyloxy)-heteroaryl compounds having heart rate lowering and/or anti-ischemic effects, methods for their preparation and pharmaceutical compositions containing them are described. The compounds correspond to the general formula I ... | 10/21/1997 |
| 5635511 | Treatment of heart rhythm disorders by administration of 3-phenylsulfonyl-3,7-diazabicyclo[3.3.1]nonane compounds. The use of 3,7,9,9-tetrasubstituted 3-phenylsulfonyl-3,7-diazabicyclo[3.3.1]nonane compounds for treating cardiac arrhytmias in larger mammals, including humans; novel antiarrhythmically active 3,7,9,9-tetrasubstituted compounds corresponding to the ... | 06/03/1997 |
| 5576327 | Treatment of heart rhythym disorders by administration of 3-phenylsulfonyl-3, 7-diazabicyclo[3.3.1]nonane compounds The use of 3,7,9,9-tetrasubstituted 3-phenylsulfonyl-3,7-diazabicyclo[3.3.1]nonane compounds for treating cardiac arrhythmias in larger mammals, including humans; novel antiarrhythmically active 3,7,9,9-tetrasubstituted compounds corresponding to the... | 11/19/1996 |
| 5547967 | (Phenylalkylaminoalkyloxy)-heteroaryl-compounds, processes and intermediates for their production and pharmaceutical compositions containing them 3-(Phenylalkylaminoalkylozy)-heteroaryl compounds having heart rate lowering and/or anti-ischemic effects, methods for their preparation and pharmaceutical compositions containing them are described. The compounds correspond to the general formula I ... | 08/20/1996 |
| 5532251 | Method of treating cardiac arrhythmia with 3-benzoyl-3, 7-diazabicyclo[3.3.1]nonane compounds The use of 3-benzoyl-3,7-diazabicyclo[3.3.1]nonane compounds of the general formula I ##STR1## in which R1 is an alkyl group having 1-6 carbon atoms or a cycloalkylalkyl group having 4-7 carbon atoms, R2 and R3 are ea... | 07/02/1996 |
| 5474988 | 5-phenylpyrrolo-1,4-benzoxazine and 5-phenylpyrrolo-1,4-benzothiazine compounds, process and intermediates for their production and pharmaceutical compositions containing them Pharmacologically active compounds of formula I ##STR1## which can be substituted in the phenyl rings and in which R1 denotes hydrogen or lower alkyl, R2 denotes hydrogen or lower alkyl, Y denotes oxygen or sulfur n represents an int... | 12/12/1995 |
| 5438068 | Method of treating colon disturbances with pharmaceutical compositions containing imidazol-1-yl compounds Use of imidazol-1-yl compounds of the general formula I ##STR1## wherein R1 denotes lower alkyl or hydrogen; m represents 2 or 3, and n represents 2 or 3; or a physiologically acceptable acid addition salt thereof for treating functional distur... | 08/01/1995 |
| 5418224 | 4,13-dioxabicyclo[8.2.1]tridecenone compounds and pharmaceutical compositions containing them Ring-contracted N-demethyl-N-isopropylerythromycin A derivatives with gastrointestinally effective motilin-agonistic properties, a method for preparing such compounds, and pharmaceutical compositions containing them.... | 05/23/1995 |
| 5378462 | Pancreatin micropellets prepared with polyethylene glycol 4000, paraffin and a lower alcohol by extrusion and rounding Pancreatin-containing micropellet cores which can be coated with a gastric juice-resistant film are prepared by extruding a mixture containing pancreatin, polyethylene glycol 4000 and a lower alcohol such as propan-2-ol to produce extrudates which break b... | 01/03/1995 |
| 5332733 | Heterocyclically substituted piperazinoakylbenzoxazine and piperazinoalkylbenzothiazine compounds, processes for preparing them, and medicaments containing them Pharmacologically active compounds corresponding to the general formula I ##STR1## which are optionally substituted in the benzene ring and in which X denotes oxygen or sulfur, Y denotes oxygen or sulfur, R1 denotes hydrogen or lower alkyl, n i... | 07/26/1994 |
| 5324725 | 7-fused 2-(piperazinoalkyl) indole derivatives, intermediates and compositions thereof Pharmacologically active compounds having anti-allergic properties corresponding to the formula I ##STR1## which can be mono- or disubstituted in the phenyl ring and their acid addition salts and/or S-mono- or dioxides of sulfur-containing compounds ... | 06/28/1994 |
| 5324732 | Crystalline fumaric acid salts of 9,9-alkylene-3,7-diazabicyclononane compounds and pharmaceutical compositions containing them 1.5 Fumaric acid salts of N,N'-di-lower alkyl-substituted 9,9-alkylene-3,7-diazabicyclo[3.3.1 ]nonanes and a process for obtaining them in stoichiometrically pure and virtually non-hygroscopic form.... | 06/28/1994 |
| 5294638 | Phenyalkylaminoalkyl compounds and pharmaceutical compositions containing them Pharmacologically active compounds corresponding to the general formula I: ##STR1## wherein m represents 1-4, n represents 2-5, R1 is hydrogen or lower alkyl, R2 is hydrogen, lower alkyl, lower alkoxy, halogen or trifluoromethyl, and... | 03/15/1994 |
| 5283243 | Piperidinoalkylbenzoxazine and piperidinoalkylbenzothiazine compounds, and medicaments containing them Pharmacologically active compounds corresponding to the formula I ##STR1## which are optionally substituted in the benzene ring and in which X denotes oxygen or sulfur, Y denotes oxygen or sulfur, R1 denotes hydrogen or lower alkyl, n is an int... | 02/01/1994 |
| 5272143 | 6-oxoazepinoindole compounds, and pharmaceutical compositions containing them Pharmacologically active compounds corresponding to the general formula I ##STR1## in which R1 represents hydrogen, a lower alkyl or cycloalkyl-alkyl group or an optionally substituted phenyl-lower alkyl group, R2 denotes hydrogen or... | 12/21/1993 |
| 5232686 | Gastroprotective pharmaceutical preparations containing N-benzyl-N-((1S,5S)-6,6-dimethylbicyclo(3,1,1)-hept-2-ylethoxy-ethyl)-mo rpholinium salts A method of inhibiting peripheral blood circulation disorders or damage such as hemorrhagic lesions induced by gastrotoxic doses of substances such as alcohol or non-steroid, antiinflammatory medicaments in the gastrointestinal tract of a mammal comprisin... | 08/03/1993 |
| 5212173 | Alkylaminoalkylamine and ether compounds, processes and intermediates for their preparation, and medicaments containing them Pharmacologically active compounds corresponding to the formula I ##STR1## in which n represents 2-5, m represents 2-6, R1 denotes hydrogen or lower alkyl, R2 represents an OR4 group in which R4 denotes lower alkyl ... | 05/18/1993 |
| 5175347 | Process for preparing cis-dihydronopol A process for preparing cis-dihydronopol and esters thereof in which corresponding esters of (-)nopol are stereoselectively hydrogenated by heterogeneous hydrogenation in the presence of a platinum, platinum oxide or ruthenium/carbon catalyst, and the res... | 12/29/1992 |
| 5164401 | Method of diuretic treatment with 3,7-diazabicyclo[3,3,1]nonane compounds A method of treating a mammal in need of diruetic treatment by administering an effective diuretic amount of a diuretically active 3,7,9,9-tetrasubstituted 3,7-diazabicyclo[3,3,1]nonane compound, diuretic pharmaceutical compositions containing an effectiv... | 11/17/1992 |
| 5096920 | 1,2-dithiol-3-thion-S-oxide compounds and pharmaceutical compositions The use of 5-phenyl-3H-1,2-dithiol-3-thion-S-oxides which are optionally substituted in the phenyl ring as active substances in hepato-protective medicaments and new 5-phenyl-3H-1,2-dithiol-3-thion-S-oxides which are substituted in the phenyl ring are des... | 03/17/1992 |
| 5013852 | 3-flavone carboxylic acid compounds Flavone-3-carboxylic acid compounds corresponding to the Formula I: ##STR1## wherein R1, R2, R3, R4 and R5 represent hydrogen, lower alkyl, halogen, hydroxy, or etherified or esterified hydroxy, and ... | 05/07/1991 |
| 5010076 | 1,7-fused 1H-indole-2-carboxylic acid-N-(1,4-benzodiazepin-3-yl)amides Compounds corresponding to the formula I ##STR1## in which R1 represents hydrogen, lower alkyl or cycloalkylalkyl with 4-7 carbon atoms, R2 represents hydrogen, halogen, lower alkyl, lower alkoxy or trifluoromethyl, and R3 | 04/23/1991 |
| 4983611 | 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane intermediates and pharmaceutical method 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds corresponding to the formula: ##STR1## wherein R1 is alkyl, cycloalkylalkyl or benzyl, R2 is hydrogen or lower alkyl, R3 is hydrogen or lower alkyl or R2 and R | 01/08/1991 |
| 4980487 | Novel valepotriate hydrin containing medicines The use of valepotriate hydrins in the prevention and treatment of disorders of the gastrointestinal tract is described, together with pharmaceutical compositions containing valepotriate hydrins and certain novel valepotriate hydrins per se.... | 12/25/1990 |
| 4976965 | Coronary affecting medicinal composition Coronary affecting medicinal compositions which in addition to a coronary affecting substance selected from the group consisting of isosorbide nitrates and dihydropyridines contain an alkylene glycol ether as a solvent.... | 12/11/1990 |
| 4965369 | Method for preparing indole carboxylic acid derivatives A method of preparing indole carboxylic acid derivatives from aniline derivatives is described which can be carried out in a single reaction vessel without any isolation of intermediate products. The method involes reacting an aniline derivative with a so... | 10/23/1990 |
| 4924004 | 1-phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them New 1-phenyl-2-aminocarbonylindole compounds are described which have the general formula I ##STR1## where R1 is a hydrogen atom, or a lower alkyl, alkenyl, cycloalkyl or cycloalkylalkyl radical, R2 is a hydrogen atom or a lower... | 05/08/1990 |
| 4912113 | 3,7-diazabicyclo(3,3,1)nonane compounds and pharmaceutical compositions containing such compounds 3,7-Diazabicyclo[3,3,1]nonane compounds having valuable heart rate-affecting pharmacological properties corresponding to the Formula I: ##STR1## wherein R1 is alkyl, cycloalkylalkyl or benzyl, R2 is lower alkyl, R3 is lowe... | 03/27/1990 |
| 4906640 | 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds and medicaments containing said compounds 3-sulfonyl-3,7-diazabicyclo[3,3,1]nonane compounds corresponding to the formula: ##STR1## wherein R1 is alkyl, cycloalkylalkyl or benzyl, R2 is hydrogen or lower alkyl, R3 is hydrogen or lower alkyl or R2 and R | 03/06/1990 |
| 4891384 | Valepotriate hydrin containing medicines used to treat uclers and motility disturbances The use of valepotriate hydrins in the prevention and treatment of disorders of the gastrointestinal tract is described, together with pharmaceutical compositions containing valepotriate hydrins and certain novel valepotriate hydrins per se.... | 01/02/1990 |
| 4886806 | Flavone-3-carboxylic acids compounds and pharmaceutical compositions containing them Falvone-3-carboxylic acid compounds corresponding to the Formula I: ##STR1## wherein R1, R2, R3, R4 and R5 represent hydrogen, lower alkyl, halogen, hydroxy, or etherified or esterified hydroxy, and ... | 12/12/1989 |
| 4879299 | Treatment of heart conditions with spartein compounds Compounds of Formula (I) S--(CH2)n--Atm (I) in which S is a 17-spartein nucleus, n is 0 or 1, and A is 2-furyl, 2-thienyl or 2-(N-loweralkyl)pyrryl when n=0, or 3-furyl or 3-thienyl when n=1, or pyridyl, or a phenyl group of Formula (II) ##STR1## in whic... | 11/07/1989 |
| 4831167 | Process for diastereoselective reduction of 3-amino-1-benzoxepin-5(2H)-ones A process for producing cis-2,3,4,5-tetrahydro-3-amino-1-benzoxepin-5-ols in which 3-amino-1-benzoxepin-5(2H)-ones are diastereoselectively reduced in a single stage by catalytic hydrogenation in the presence of a platinum oxide catalyst and an equivalent... | 05/16/1989 |
| 4814345 | 1-phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them Novel 1-phenyl-2-aminocarbonylindole compounds are disclosed having the general formula I ##STR1## wherein R1 is an aliphatic or aromatic acyl group or an optionally substituted benzyl group; R2 is hydrogen or a lower alkyl radi... | 03/21/1989 |
| 4803198 | 1-Phenyl-2-aminocarbonylindole compounds, preparation thereof and pharmaceutical compositions containing them New 1-phenyl-2-aminocarbonylindole compounds are described which have the general formula I ##STR1## where R1 is a hydrogen atom, or a lower alkyl, alkenyl, cycloalkylalkyl radical, R2 is a hydrogen atom or a lower alkyl ra... | 02/07/1989 |
| 4771044 | Tetraoxo compounds and pharmaceutical compositions Tetraoxo compounds of the Formula (I) ##STR1## wherein R1 is an alkyl, alkenyl, phenylalkyl or cycloalkylalkyl group, R2 and R3 are each independently an alkyl or phenyl group or together denote an alkylene group, W i... | 09/13/1988 |
| 4755520 | Spartein compounds, their preparation and use Compounds of Formula (I) in which S is a 17-spartein nucleus n is 0 or 1 and A is 2-furyl, 2-thienyl or 2-(N-alkyl)pyrryl when n=0, or 3-furyl or 3-thienyl when n=1, or pyridyl or a phenyl group of Formula (II) ##STR1## in which at least one of R1 | 07/05/1988 |
| 4722941 | Readily absorbable pharmaceutical compositions of per se poorly absorbable pharmacologically active agents and preparation thereof A readily absorbable pharmaceutical composition of pharmacologically active agents, which per se are poorly absorbable, is disclosed which comprises a pharmacologically effective amount of at least one such pharmacologically active agent distributed in a ... | 02/02/1988 |
| 4714709 | N-(2,10-dioxa-tricyclo-[5,3,1,03,8 ]-undecane-5-yl)-tryptamine derivatives and medical compositions thereof N-(2,10-dioxa-tricyclo-[5,3,1,03,8 ]-undecane-5-yl)-tryptamine compounds corresponding to the formula ##STR1## with blood-pressure lowering effects, a method of producing such compounds and pharmaceutical compositions incorporating such co... | 12/22/1987 |
