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| Number | Title | Issue Date |
| 5661008 | Recombinant human factor VIII derivatives A DNA sequence coding for a biologically active recombinant human factor VIII derivative, comprising a first DNA segment coding for the amino acids 1 through 740 of human factor VIII and a second DNA segment coding for the amino acids 1649 through 2332 of... | 08/26/1997 |
| 5516796 | Thioprostaglandins and -prostaglandin-like compounds and therapeutic uses thereof Thiosubstituted prostaglandin derivatives and related compounds having the general structure ##STR1## useful as intraocular pressure reducing agents; pharmaceutical compositions containing such compounds; and methods of treatment using such comp... | 05/14/1996 |
| 5505966 | Therapeutical composition and process for its preparation A colon selective pharmaceutical composition for oral delivery of one or more therapeutically active substances, comprises (i) a matrix core having the active substance or substances dispersed therein, and (ii) an outer cover layer without any active subs... | 04/09/1996 |
| 5476667 | Method for drug formulation and a pharmaceutical composition A melt granulating method for the production of pellets (spheres) which contain a therapeutically active substance of high-dosage type. The method is characterized by: (i) mechanically working a mixture which contains (a) the active substance in cohesive ... | 12/19/1995 |
| 5466833 | Process for the preparation of 13,14-dihydro-15(R)-17-phenyl-18,19,20-trinor-PGF2 isopropyl ester The invention relates to a novel process for the preparation of 13,14-dihydro-15 (R)-17-phenyl-18,19,20-trinor-PGF2 isopropyl ester of the formula (I)--wherein R stands for saturated or unsaturated straight, branched or cyclic C1-7 | 11/14/1995 |
| 5422369 | Prostaglanddin derivatives for the treatment of glaucoma or ocular hypertension This invention relates a method for topical treatment of glaucoma or ocular hypertension by administration of an effective intraocular pressure reducing amont of a prostaglandin derivative of PGA, PGB, PGE and PGF, in which the omega chain contains a ring... | 06/06/1995 |
| 5422368 | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension The invention relates to ophthalmological compositions for topical treatment of glaucoma or ocular hypertension comprising an effective intraocular pressure reducing amount of a prostaglandin derivative of PGA, PGB, PGD, PGE or PGF, in which the omega cha... | 06/06/1995 |
| 5321128 | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension This invention relates a method for topical treatment of glaucoma or ocular hypertension by administration of an effective intraocular pressure reducing amount of a prostaglandin derivative of PGA, PGB, PGE and PGF, in which the omega chain contains a rin... | 06/14/1994 |
| 5302718 | Compounds containing an amino salicylic acid moiety linked to a sulphapyridine moiety via stable bridge A compound of the formula Het--NR--SO2 --Ph2 --A--Ph1 (COOH)(OH) and tautomeric form, salts, solvates, C1-6 alkyl esters and pharmaceutical compositions of the compound. Ph1 and Ph2 are ben... | 04/12/1994 |
| 5276014 | Treatment of human lactation failure The invention relates to the use of hGH, hGRF, hIGF-1, hIGF-2 or analogs of these or a mixture of two or more of these, alone or in conjunction with lactational enhancers for the treatment of human lactation failure. It also relates to the use of hGH, hGR... | 01/04/1994 |
| 5230916 | Ascorbic acid complex having antioxidant function and improved solubility in lipid materials A natural antioxidant for stabilizing polyunsaturated oils is disclosed. This oil-soluble antioxidant is prepared by dissolving ascorbic acid in a polar solvent, dissolving phospholipid in a non-polar solvent and then mixing the ascorbic acid solution wit... | 07/27/1993 |
| 5229498 | Method of cleansing a protein from multivalent metal ions bound thereto A method is provided for cleansing a protein from multivalent metal ions bound thereto, these ions being released from the protein by exchanging the ions with monovalent metal ions, whereafter the multivalent metal ions are removed. The release and remova... | 07/20/1993 |
| 5223537 | Method and composition for treatment of gastric and duodenal disorders The invention is related to the field of treating gastric and duodenal disorders and more specifically to the use of certain 13,14-dihydro-prostaglandin E derivatives, especially of PGE2, which are modified to contain a ring structure in the om... | 06/29/1993 |
| 5217490 | Ultraviolet light absorbing intraocular implants Intraocular implants having optical lenses that are light, non-toxic, biocompatible, nonleachable in the presence of eye fluids and absorb at least 90% of the ultraviolet light in the 300-380 nm wavelength range but are transparent to most of the visible ... | 06/08/1993 |
| 5190759 | Composition and method for prevention of adhesions between body tissues A composition for the prevention of adhesions between body tissues after a surgical operation, containing dextran and hyaluronic acid. The composition further claims the use of said components for the preparation of such a composition as well as its use a... | 03/02/1993 |
| 5188835 | Intravaginal devices The invention concerns an intravaginal device comprising a combination of 17ଲ-estradiol and a supporting matrix for treating hypoestrogenic women. The device releases continously 17ଲ-estradiol at a rate of about 0.5 to about 25 μg/24 h. The i... | 02/23/1993 |
| 5182081 | Product to be used in occlusive epicutaneous testing for the purpose of demonstrating contact allergy to formaldehyde A test strip having at least one patch thereon and intended for use in occlusive epicutaneous testing in order to detect contact allergy to formaldehyde. The characteristic feature is that on at least one of the patches the test substance is a reversible ... | 01/26/1993 |
| 5135540 | Intraocular lens An intraocular lens having a substantially circular optical portion and two separate fixation arms each having an inner end and an outer free end. The fixation arms are each attached to the optical portion via a short connecting member which extends subst... | 08/04/1992 |
| 5114971 | Prostaglandin derivatives for the treatment of glaucoma or ocular hypertension 11-epi PGF2 alpha esters are employed in treating glaucoma or ocular hypertension.... | 05/19/1992 |
| 5087424 | Apparatus for mechanical processing of a sample and a member of such an apparatus An apparatus for facilitating the release of an ingredient of a plastic or elastic sample of a pharmaceutical or confectionery material while the sample is in contact with a liquid medium which includes a base, a fixed lower jaw, a movable upper jaw and a... | 02/11/1992 |
