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Assignee: Juridical Foundation the Chemo-sero-therapeutic Research Institute


Location: Kumamoto-shi, JP
No. of patents: 11

NumberTitleIssue Date
8173777Recombinant Factor X with no glycosylation and method for preparing the same
A Factor X (hereinafter referred to as “FX”) with a high activity is provided. The present invention relates to a method for efficiently preparing a recombinant, two-chain FX which comprises intervening glycosylation at such an amino acid sequence that is essent...
05/08/2012
8106015Method for enhancing immune response with peptide
An object of the present invention is to provide a safe and effective method for enhancing an immune response and a medicament for preventing or treating Alzheimer disease comprising amyloid β peptide that induces an enhanced immune response. An amyloid β peptide ...
01/31/2012
8043629Bioabsorbable synthetic nonwoven fabric holding thrombin
A safe and effective hemostatic is provided. The invention relates to a bioabsorbable synthetic nonwoven fabric holding thrombin as an effective ingredient and a hemostatic comprising said bioabsorbable synthetic nonwoven fabric. The bioabsorbable synthetic nonwoven...
10/25/2011
7960508Peptide having cytotoxicity inhibitory activity and method of screening these peptide having cytotoxicity inhibitory activity
A peptide fragment or a series of peptide fragments containing one or more selenocysteine that has a lowered toxicity than selenocystine and that exhibits a cytotoxicity-inhibitory activity. The peptide fragment or a series of peptide fragments according to the pres...
06/14/2011
7807161Humanized anti-human osteopontin antibody
The present invention provides a humanized anti-human osteopontin antibody having better activities (antigen binding activity, leukocyte migration inhibitory activity and the like) and/or stability (resistance to heat, low-pH conditions, denaturants and the like) th...
10/05/2010
7763249Human anti-amyloid β peptide antibody and fragment of said antibody
A human anti-amyloid β peptide (hereinafter referred to as “Aβ”) antibody that binds to Aβ to thereby inhibit aggregation of Aβ molecules, and a fragment of said antibody are provided. The antibody and a fragment thereof according to the present invention, c...
07/27/2010
7704951Method for ameliorating dyskinesia
A novel medicament for treating neurodegenerative diseases, especially for ameliorating dyskinesia, comprising as an active ingredient selenoprotein P and/or a peptide fragment or a series of peptide fragments derived from said protein is provided. The novel medicam...
04/27/2010
7598349Antibodies to peptide fragments having cell death-inhibitory activity
The present invention provides a peptide fragment or a series of peptide fragments having a cell death-inhibitory activity, having the amino acid sequence consisting of 103 amino acid residues at the C-terminal of selenoprotein P, or having said amino acid sequence ...
10/06/2009
7491803Human anti-human interleukin-18 antibody, fragment thereof and method for using same
A human-derived human anti-human IL-18 antibody of the present invention is an antibody against human IL-18, the antibody including: an H-chain complementarity determining region consisting of (a) a polypeptide consisting of amino-acid sequences represented by SEQ I...
02/17/2009
7326543Gene encoding protein from merozoite of , recombinant protein obtained with said gene and use thereof
The present invention provides a gene encoding a protein from merozoite of Babesia caballi, a recombinant protein of Babesia caballi, and an antibody capable specifically binding to a 48 kDa protein of rhoptry of Babesia caballi merozoite. In ac...
02/05/2008
7241873Recombinant anti-osteopontin antibody and use thereof
A recombinant antibody in which at least the constant regions in the heavy chain and the light chain have been converted into human-origin regions and which inhibits the binding of an integrin recognizing the RGD sequence to osteopontin or its fragment and inhibits ...
07/10/2007
 
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