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| Number | Title | Issue Date |
| 7445930 | Method for the production and purification of adenoviral vectors The present invention addresses the need to improve the yields of viral vectors when grown in cell culture systems. In particular, it has been demonstrated that for adenovirus, the use of low-medium perfusion rates in an attached cell culture system provides for imp... | 11/04/2008 |
| 7423015 | Antihelminthic drugs as a treatment for hyperproliferative diseases The present invention is directed to the use of benzimidazole derivatives for the treatment of tumors and in combination with tumor suppressor gene therapy. In a particular embodiment, treatment of p53-positive tumors with benzimidazole derivatives induces p53 expre... | 09/09/2008 |
| 7419808 | Methods and compositions for the production of adenoviral vectors The present invention addresses the need to improve the yield of adenovirus when grown in cell culture systems. In particular, it has been demonstrated that for adenovirus, the use of infection temperatures lower than 37° C. in a cell culture system results in impr... | 09/02/2008 |
