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Assignee: Instrumentation Laboratory Inc.


Location: Lexington, MA
No. of patents: 44

1    
NumberTitleIssue Date
7022219Automated system for continuously and automatically calibrating electrochemical sensors
An electrochemical sensor system that continuously monitors and calibrates the sensors included in the system. The invention also includes a method for determining failure patterns of a sensor and incorporating into an electrochemical sensor system the ability to re...
04/04/2006
6960466Composite membrane containing a cross-linked enzyme matrix for a biosensor
An electrochemical sensor system and membrane and method thereof for increased accuracy and effective life of electrochemical and enzyme sensors. ...
11/01/2005
6896793Liquid junction reference electrode and methods of use thereof
The invention relates to a durable and reliable miniature liquid junction reference electrode for use with at least one electrode (e.g., an electrochemical sensor cartridge) for measuring certain characteristics of a fluid sample such as blood or other body fluid.
05/24/2005
6872297Analytical instruments, biosensors and methods thereof
An electrochemical sensor system and membrane and method thereof for increased accuracy and effective life of electrochemical and enzyme sensors. ...
03/29/2005
6855509Protein S functional assay and kit therefor
The invention relates generally to a new functional protein S assay and kit that is based on the ability of endogenous protein S to prolong clotting time. In the assay procedure, a test plasma sample is diluted with protein S deficient plasma, followed by the additi...
02/15/2005
6652720Analytical instruments, biosensors and methods thereof
An electrochemical sensor system and membrane and method thereof for increased accuracy and effective life of electrochemical and enzyme sensors....
11/25/2003
4499053Fluid sampling
Liquid sampling apparatus includes a hollow sample intake tube that has an inlet port adapted to receive sample material to be analyzed, and is mounted on a support for movement about a fixed pivot between a reset position and at least two sample intake p...
02/12/1985
4485174Hemoglobin-based blood gas control
Blood gas control containing hemoglobin, a pH buffering agent, and a reduced pyridine nucleotide capable of participating in a reaction which reduces methemoglobin to normal hemoglobin....
11/27/1984
4468608Electrochemical sensor instrumentation
An electrochemical sensor system includes a high impedance ion selective electrode and an electrode test circuit that has an isolation capacitor connected between the output signal lead from the ion selective electrode and a test voltage terminal, and a m...
08/28/1984
4466878Electrochemical electrode assembly
A replaceable cartridge assembly for use with electrochemical analysis apparatus includes a housing of electrically insulating material that defines an annular electrolyte chamber with coupling structure at one end of the housing and a chamber port at the...
08/21/1984
4463616Sample handling apparatus
Sample handling apparatus includes a disposable, single use sample vessel that includes reclosable port structure, and coupling structure adjacent said port structure. Cooperating sample transfer structure for detachable connection to the coupling structu...
08/07/1984
4462685Spectroanalytical system
An atomic absorption system comprising a radiation source that emits spectral line radiation characteristic of an element to be analyzed, an analysis region open to passage of the beam of radiation from the source and in which a sample of the substance to...
07/31/1984
4448889Fluid analysis
In a method for colorimetric determination of calcium, the sample to be analyzed is mixed with a dye reagent of pH value at which that reagent does not produce a predetermined change when complexed with calcium ions; a first colorimetric measurement is ma...
05/15/1984
4447544Method and reagent for determining inorganic phosphate in biological sample
An aqueous reagent for determining inorganic phosphate in a protein-containing liquid biological sample comprises a molybdate salt, an acid capable of reacting with the molybdate salt to form molybdic acid for complexation with phosphate to form phosphomo...
05/08/1984
4446106Analysis system
A chemical analysis system for analyzing a plurality of independent specimens that have time varying characteristics includes a circumferential array of analysis regions that hold the specimens. The analytical regions are sequentially and repetitively sen...
05/01/1984
4443407Analysis system
An analysis system for measuring a plurality of parameters of a fluid sample comprises a housing, and a flow-through cell in the housing that has opposed surfaces with at least two ports in each surface. One of the ports is an inlet port, a second of the ...
04/17/1984
4410631Compensated reference liquid
A reference liquid system for use with a chemical analyzer that has a plurality of ion selective electrodes comprises a plurality of reference liquids, each of which has a first salt component such that ions of a first element to be measured are present i...
10/18/1983
4398333Manipulating tool
A storage and manipulating tool for replacement plunger heads includes a set of storage cavities in which replacement plunger heads (syringe tips) are stored. Each plunger head has an annular flange, and a socket for receiving the end of a cooperating plu...
08/16/1983
4399362Liquid handling apparatus
A clinical analyzer system flows a small volume (less than 200 microliters) of liquid sample to be analyzed from an inlet port past a sensor array to a series of analysis chambers. The sensor array includes two optical sensor units that are spaced a fixed...
08/16/1983
4373812Cuvette assembly
An improved analytical cuvette assembly includes structure defining a first chamber region that has a loading port through which a first reaction component is introduced for storage, structure defining a second chamber region having a loading port through...
02/15/1983
4369127Blood gas control
A blood gas control liquid comprises a stable oil-in-water emulsion that has an oxygen solubility coefficient of at least 10 ml O2 per 100 ml emulsion and a viscosity of less than 10 centipoises. The emulsion includes water, 5-40 percent by vol...
01/18/1983
4367042Spectroanalytical system
A spectroanalytical instrument includes burner structure and a nebulizer for furnishing sample in fog form for flow through a premix chamber to the burner structure. Flow structure extending from a chamber port to a drain port provides a condensate flow p...
01/04/1983
4366038Method of casting in place an ion-sensitive membrane and ion-sensitive electrode using said membrane
A one-piece disposable electrode comprising a sealed chamber containing an electrolyte solution, silver-silver chloride conductor in the electrolyte solution in the chamber and a cast-in-place membrane essentially flush with an exterior wall of this chamb...
12/28/1982
4361253Liquid transfer device
A device for dispensing liquid from an ampul or the like has a body that defines a cavity with an open entrance end for receiving an ampul. An annular seal in the cavity is in sealing engagement with an ampul as the ampul is telescopically inserted into t...
11/30/1982
4361540Analysis system
An analysis system for measuring a plurality of parameters of a fluid sample comprises a housing, and a flow-through cell in the housing that has opposed surfaces with at least two ports in each surface. One of the ports is an inlet port, a second of the ...
11/30/1982
4361539Analysis system
An analysis system for measuring a plurality of parameters of a fluid sample comprises a housing, and a flow-through cell in the housing that has opposed surfaces with at least two ports in each surface. One of the ports is an inlet port, a second of the ...
11/30/1982
4361401Automatic sample deposition in flameless analysis
Method and apparatus for automatically depositing predetermined reproducible amounts of nebulized samples into a furnace atomizer of an atomic absorption spectrophotometer, the atomizer being provided with an aperture, wherein a plurality of sample contai...
11/30/1982
4343705Biological liquid fractionation using alternate opposite flow directions across a membrane
A fractionation system for providing a clarified fraction or a fraction for analysis of biological fluids and the like includes a disposable filtration vessel with a first reservoir chamber adapted to receive the fluid to be fractionated, a second reservo...
08/10/1982
4338280Fluid sampling
A liquid sample analyzer has an analysis chamber adapted to receive sample material to be analyzed, sensor means coupled to the analysis chamber for providing an output signal related to a constituent of the sample material, and sampler apparatus that inc...
07/06/1982
4330776Keyboard type of input control system for an analytical instrument
An input control includes first and second keyboard assemblies mounted on a common structural unit, an encoder on the unit, and a plurality of output conductors connected to the encoder for transmitting a binary coded signal when a key is actuated. The fi...
05/18/1982
4326802Dual monochromator type of spectroanalysis system
A highly accurate, rapid scanning monochromator type of spectroanalysis system employs a source of the plasma emission type, a filtering monochromator, and a resolving monochromator. Each monochromator has a dispersing element and the two dispersing eleme...
04/27/1982
4323537Analysis system
A liquid handling system that is particularly useful in a clinical analysis system and includes first and second storage chambers, each with a port through which liquid may be flowed into and from the storage chamber. The storage chambers and their ports ...
04/06/1982
4314970Analysis system
A multicuvette rotor assembly for use in a clinical chemistry analyzer of the centrifugal type includes a body member that defines a circumferential array of spaced radially extending recesses, with a divider member in each recess to define a first chambe...
02/09/1982
4306175Induction plasma system
An induction plasma system includes a plasma chamber, a high frequency electrical coil that surrounds the chamber, and an oscillator for energizing the coil to establish a plasma maintaining condition in the chamber. The oscillator tank circuit includes t...
12/15/1981
4304257Valve with flexible sheet member
A valve that is particularly useful in biological fluid handling systems includes a body member that has a firm and stable support surface and a flexible sheet member that has a surface for conforming and mating engagement with the surface of the valve bo...
12/08/1981
4299794Analytical system for analyzing CO2 content of a fluid
A total carbon dioxide analyzer system has a reaction chamber that includes a tube and a piston mounted for sliding movement in the tube to change the volume of the chamber. A valve coupled to the chamber has a sample inlet port and a reagent inlet port, ...
11/10/1981
4299728Blood gas control
A blood gas control liquid comprises water, 5-40 percent by volume of a water-insoluble perfluorinated compound material that has an oxygen solubility coefficient, at one atmosphere pressure, 25° C., and a volumetric proportion of 15 percent of at least ...
11/10/1981
4298026Spool valve
A valve includes housing and body members that have cylindrical valve surfaces. The valve body being centered in the housing by an array of at least three resilient support elements circumferentially spaced about the valve body. The valve body includes a ...
11/03/1981
4283262Analysis system
A system for analyzing a biological fluid specimen or the like includes an analysis chamber and an electrochemical electrode measuring system connected in sensing relation to the analysis chamber. A flow network connects a sample inlet port and an auxilia...
08/11/1981
4282182Package sampling system
Apparatus for analyzing the contents of a sealed package includes a package alignment assembly, and a probe assembly that has a puncturing tip. The package alignment assembly includes a positioning support surface in alignment with the puncturing tip and ...
08/04/1981
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