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| Number | Title | Issue Date |
| 7732424 | Purine derivatives and methods of use thereof The present invention relates to Purine Derivatives; compositions comprising an effective amount of a Purine Derivative; and methods for reducing an animal's core body temperature, protecting an animal's heart against myocardial damage during cardioplegia; or for tr... | 06/08/2010 |
| 7652028 | Indenoisoquinolinone analogs and methods of use thereof The present invention relates to Indenoisoquinolinone Analogs, compositions comprising an effective amount of an Indenoisoquinolinone Analog and methods for treating or preventing an inflammatory disease, a reperfusion injury, diabetes mellitus, a diabetic complicat... | 01/26/2010 |
| 7642250 | N-benzyl substituted pyridyl porphyrin compounds and methods of use thereof The present invention relates to N-Benzyl-Substituted Pyridyl Porphyrin Compounds and compositions comprising an effective amount of N-Benzyl-Substituted Pyridyl Porphyrin Compounds. The N-Benzyl-Substituted Pyridyl Porphyrin Compounds include compounds of the follo... | 01/05/2010 |
| 7432369 | Pyridyl-substituted porphyrin compounds and methods of use thereof The present invention relates to Pyridyl-Substituted Porphyrin Compounds, compositions comprising an effective amount of a Pyridyl-Substituted Porphyrin Compound and methods for treating or preventing injury due to exposure to a reactive species, erectile dysfunctio... | 10/07/2008 |
| 7423144 | Purine Derivatives as adenosine Areceptor agonists and methods of use thereof The invention relates to Purine Derivatives; compositions comprising an effective amount of a Purine Derivative; and methods for reducing an animal's rate of metabolism, protecting an animal's heart against myocardial damage during cardioplegia; or for treating or p... | 09/09/2008 |
| 7393955 | Isoquinoline derivatives and methods of use thereof The invention provides novel classes of Isoquinoline Derivatives. Pharmaceutical compositions and methods of making and using the compounds, are also described. ... | 07/01/2008 |
| 7381722 | Tetracyclic amino and carboxamido compounds and methods of use thereof The present invention relates to Tetracyclic Amino Compounds and Tetracyclic Carboxamido Compounds, compositions comprising an effective amount of a Tetracyclic Amino Compound or a Tetracyclic Carboxamido Compound and methods for treating or preventing an inflammato... | 06/03/2008 |
| 7268143 | Isoquinoline derivatives and methods of use thereof The invention provides novel classes of Isoquinoline Derivatives. Pharmaceutical compositions and methods of making and using the compounds, are also described. ... | 09/11/2007 |
| 7217709 | Tetracyclic benzamide derivatives and methods of use thereof The invention relates to Tetracyclic Benzamide Derivatives; compositions comprising a Tetracyclic Benzamide Derivative; and methods for treating or preventing an inflammatory disease, a reperfusion disease, an ischemic condition, renal failure, diabetes, a diabetic ... | 05/15/2007 |
| 7135491 | 5-Aryltetrazole compounds and uses thereof The present invention relates to 5-Aryltetrazole Compounds, compositions comprising an effective amount of a a 5-Aryltetrazole Compound, and methods for treating an inflammation disease, a reperfusion disease, or hyperuricemia in an animal in need thereof comprising... | 11/14/2006 |
| 7087631 | Aryltetrazole compounds, and compositions thereof The present invention relates to 5-Aryltetrazole Compounds, compositions comprising an effective amount of a 5-Aryltetrazole Compound, and methods for treating an inflammation disease, a reperfusion disease, or hyperuricemia in an animal in need thereof comprising a... | 08/08/2006 |
| 7078423 | 5-Aryltetrazole compounds, compositions thereof, and uses therefor The present invention relates to 5-Aryltetrazole compounds, compositions comprising a 5-Aryltetrazole compound, and methods for treating an inflammation disease, a reperfusion disease, hyperuricemia, gout, or tumor-lysis syndrome in an animal in need thereof compris... | 07/18/2006 |
| 6958324 | Inosine compounds and their use for treating or preventing an inflamation or a reperfusion disease Inosine compounds, compositions comprising an inosine compound and methods for treating or preventing an inflammation disease or a reperfusion disease comprising administering an effective amount of an inosine compound to a patient in need thereof are disclosed.... | 10/25/2005 |
| 6956035 | Isoquinoline derivatives and methods of use thereof The invention provides novel classes of Isoquinoline Derivatives. Pharmaceutical compositions and methods of making and using the compounds, are also described. ... | 10/18/2005 |
| 6903079 | Nucleoside compounds and compositions thereof The invention provides a novel class of substituted nucleoside derivatives having the formula: A-Z1-L-Z2-G wherein: A and G are connected via Z1 and Z2 respectively, to a linker, L; and A i... | 06/07/2005 |
| 6828319 | Substituted indeno[1,2-c]isoquinoline derivatives and methods of use thereof The invention provides novel classes of substituted Indeno[1,2-c]isoquinoline Compounds. Pharmaceutical compositions and methods of making and using the compounds, are also described. ... | 12/07/2004 |
| 6534651 | 7-Substituted isoindolinone inhibitors of inflammation and reperfusion injury and methods of use thereof The invention provides a novel class of substituted isoindolinone derivatives, useful for the treatment of inflammation and reperfusion injuries. Pharmaceutical compositions, and methods of making and using the compounds, or pharmaceutically acceptable sa... | 03/18/2003 |
| 6531464 | Methods for the treatment of neurodegenerative disorders using substituted phenanthridinone derivatives This invention provides a novel class of substituted 6(5H)phenanthridinone compounds. The invention also includes pharmaceutical compositions, and methods of making and using the compounds, or a pharmaceutically acceptable salt, hydrate, prodrug, or mixtu... | 03/11/2003 |
