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Assignee: Inhibitex, Inc.


Location: Alpharetta, GA
No. of patents: 12

NumberTitleIssue Date
7968100Surface proteins from coagulase-negative staphylococci and that generate cross-reactive monoclonal and polyclonal antibodies
Surface proteins are provided which generate polyclonal and monoclonal antibodies which are cross-reactive to both coagulase-positive staphylococcus bacteria, such as S. aureus and to coagulase-negative bacteria, such as S. epidermidis and S....
06/28/2011
7850974Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
A bioinformatic method for identifying and isolating proteins and peptides with MSCRAMM®-like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, and proteins and peptides obtained th...
12/14/2010
7666438Multicomponent vaccines
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. By careful s...
02/23/2010
7615616Bioinformatic method for identifying surface-anchored proteins from gram-positive bacteria and proteins obtained thereby
A bioinformatic method is provided for identifying and isolating proteins with MSCRAMM®—like characteristics from Gram positive bacteria, such as Enterococcus, Staphylococcus, Streptococcus and Bacillus bacteria, which can then be utilized in method...
11/10/2009
7381793Extracellular matrix-binding proteins from
Isolated extracellular matrix-binding proteins, designated ClfB, SdrC, SdrD and SdrE, and their corresponding amino acid and nucleic acid sequences and motifs are described. The proteins, peptides, fragments thereof or antigenic portions thereof are useful for the p...
06/03/2008
7364738Monoclonal antibodies to the CLFA protein and method of use in treating infections
Monoclonal antibodies which can bind to the ClfA protein and which are generated from binding subdomains or active fragments of the ClfA protein from Staphylococcus aureus, including the active fragments proteins from its fibrinogen binding domain such as Clf...
04/29/2008
7241592Cross-reactive displacing antibodies from collagen-binding proteins and method of identification and use
Antibodies to the CNA protein and to other regions from the collagen binding domain, including domain CNA19, are provided, and antibodies produced in this manner have been shown to be cross reactive to both Staphylococcus aureus and Staphylococcus epidermi...
07/10/2007
7045131Staphylococcal immunotherapeutics via donor selection and donor stimulation
A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection or preparation of a d...
05/16/2006
6979446Monoclonal antibodies to the ClfA protein and method of use in treating or preventing infections
Monoclonal antibodies which can bind to the ClfA protein and which are generated from binding subdomains or active fragments of the ClfA protein from Staphylococcus aureus, including the active fragments proteins from its fibrinogen binding domain such as Clf...
12/27/2005
6841154Cross-reactive monoclonal and polyclonal antibodies which recognize surface proteins from coagulase-negative staphylococci and Staphylococcus aureus
Polyclonal and monoclonal antibodies which are cross-reactive to both coagulase-positive staphylococcus bacteria, such as S. aureus and to coagulase-negative bacteria, such as S. epidermidis and S. hemolyticus, are provided which can recognize s...
01/11/2005
6703025Multicomponent vaccines
Multicomponent vaccines are provided which aid in the prevention and treatment of staphylococcal infections and which include certain selected combinations of bacterial binding proteins or fragments thereof, or antibodies to those proteins or fragments. B...
03/09/2004
6692739Staphylococcal immunotherapeutics via donor selection and donor stimulation
A method and composition for the passive immunization of patients infected with or susceptible to infection from Staphylococcus bacteria such as S. aureus and S. epidermidis infection is provided that includes the selection or preparation of a donor plasm...
02/17/2004
 
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