Did You Know...
...that the Slinky toy was the result of a failed attempt by engineer Richard James to produce an antivibration device for ship instruments? His goal was to develop a spring that would instantaneously counterbalance the wave motion that rocks a ship at sea. Instead, he developed the Slinky.
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| Number | Title | Issue Date |
| 7112580 | 3-nitrogen-6, 7-dioxygen steroids and uses related thereto A compound of the formula: and pharmaceutically acceptable salts, solvates, stereoisomers and prodrugs thereof, in isolation or in mixture, wherein R groups are as defined by the present specification. The compou... | 09/26/2006 |
| 7067682 | 6,7-Oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 06/27/2006 |
| 6982329 | Process improvements in steroid chemistry Steroids containing a cyclohexene moiety are efficiently oxidized to the corresponding α,β-unsaturated ketone using copper iodide and t-butyl hydroperoxide. A steroid compound containing the α,β-unsaturated ketone structure is efficiently converted to the corres... | 01/03/2006 |
| 6949533 | 6,7-Oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 09/27/2005 |
| 6770658 | Substituted γ-phenyl-Δ-lactams and uses related thereto γ-Phenyl-substituted Δ-lactams are disclosed. They may be formulated into pharmaceutical compositions, and/or used in the treatment or prevention of inflammation or other conditions or disease states. ... | 08/03/2004 |
| 6706701 | 6, 7-oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substitution at C6 an... | 03/16/2004 |
| 6696580 | Process for the production of 6,7-diols of steroidal compounds Steroids containing a cyclohexene moiety are efficiently oxidized to the corresponding ,ଲ-unsaturated ketone using copper iodide and t-butyl hydroperoxide. A steroid compound containing the ,ଲ-unsaturated ketone structure is effi... | 02/24/2004 |
| 6635629 | 3-nitrogen-6,7-dioxygen steroids and uses related thereto A compound of the formula ##STR1## or pharmaceutically acceptable salts, solvates, and stereoisomers thereof, in isolation or in mixture, wherein the R groups are as defined by the present specification. The compounds may be formulated into pharmaceutical... | 10/21/2003 |
| 6555572 | Benzylated PDE4 inhibitors The present invention is directed to a method for reducing the emetogenic effects of PDE inhibitors, and more particularly is directed to compounds having PDE4 inhibition activity with little or no emetogenic side-effects, and chemical methods including b... | 04/29/2003 |
| 6458829 | Substituted γ-phenyl-Ɗ-lactones and analogs thereof and uses related thereto γ-Phenyl-substituted Ɗ-lactones and analogs thereof, including lactams, are disclosed. They may be formulated into pharmaceutical compositions, and/or used in the treatment or prevention of inflammation or other conditions or disease states.... | 10/01/2002 |
| 6046185 | 6,7-oxygenated steroids and uses related thereto Steroid compounds having various oxygen substitution on the steroid nucleus are disclosed. A specific functionality present on many of the steroid compounds is oxygen substitution at both of positions 6 and 7. Thus, certain steroids have oxygen substituti... | 04/04/2000 |
