Did You Know...
...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 8106231 | Process for the preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt A process for the enantioselective preparation of (2R,3S)-3-phenylisoserine methyl ester acetate salt of formula (I) which is an useful building block for the synthesis of taxane derivatives. The process involves the resolution of racemic threo-phenylisoserine amide... | 01/31/2012 |
| 8101215 | Process for cosmetic treatment using ferutinine from genus plants The invention relates to a process for cosmetic treatment, including the reduction of superficial and deep wrinkles, using ferutinine from Ferula spp extracts. ... | 01/24/2012 |
| 8092844 | Combinations of vasoactive agents and their use in the treatment of sexual dysfunctions This invention relates to combinations of vasoactive substances which are useful in the treatment of sexual dysfunctions associated with poor local blood supply and/or insufficient lubrication. The active compounds are selected from a: esculoside or vis... | 01/10/2012 |
| 8084067 | Phospholipid complexes of olive fruits extracts having improved bioavailability Phospholipids complexes of olive fruits extracts or compositions containing it having improved bioavailability. ... | 12/27/2011 |
| 8076351 | Camptothecin derivatives with antitumor activity Novel camptothecin derivatives having antitumor activity, the processes for the preparation thereof, the use thereof as antitumor drugs and pharmaceutical compositions containing them. ... | 12/13/2011 |
| 8013151 | Process for the preparation of galanthamine hydrobromide A process for the purification of galanthamine (I) comprising precipitation of galanthamine hydrobromide from a mixture of alkaloids obtained from a plant of the Amaryllidaceae family containing galanthamine, treatment of the hydrobromide with alkali, extraction and... | 09/06/2011 |
| 7993683 | Compositions for the treatment of chronic degenerative inflammatory conditions Compositions comprising: saligenin or derivatives thereof or Salix ssp extracts containing from 10 to 50% of saligenin; substantially pure andrographolide or andrographolide enriched Andrographis panicula... | 08/09/2011 |
| 7976881 | Combinations of vasoactive agents, their use in the pharmaceutical and cosmetic field, and formulations containing them Combinations of vasoactive substances which act at venous or arterial level with phosphodiesterase inhibitors including phosphodiesterase V, in particular: visnadin or esculoside; at least one compound selected from icarin or derivatives thereof or extracts containi... | 07/12/2011 |
| 7976878 | Use of winter savory () or the extracts thereof for the preparation of medicaments for the treatment of the premature ejaculation The use of Winter savory or its purified extracts rich in rosmarinic acid, the use of rosmarinic acid and the extracts containing it for the preparation of medicaments for the treatment of premature ejaculation. ... | 07/12/2011 |
| 7910334 | Biotransformation of colchicinoid compounds The present invention relates to a biotransformation process, effected by means of selected microbial strains, for the preparation of 3-O-glycosyl derivatives of colchicinoid compounds. ... | 03/22/2011 |
| 7910139 | Compositions for the treatment of affections of the oral cavity and upper respiratory tract Compositions for the treatment of the affections of the oral cavity and upper respiratory tract include anthocyanosides, procyanidins and phloroglucinols. The anthocyanosides are derived from Vaccinium myrtillus extract, the procyanidins are derived from a | 03/22/2011 |
| 7901718 | Process for the extraction, purification and enzymatic modification of soy 7S globulin α′ subunit for use as hypocholesterolemizing agent A process for the extraction, purification and enzymatic modification of β-conglycinin α′ subunit, wherein β-conglycinin is selectively extracted from ground, defatted soy, then precipitated by treatment with aqueous ethanol; the enriched fraction is then subje... | 03/08/2011 |
| 7887855 | Formulations containing and extracts which are useful in the treatment of obesity The present invention relates to a Cynara scolymus extract with a high content of caffeoylquinic acids, and a composition containing said Cynara scolymus extract with a Phaseolus vulgaris extract. Said composition is useful in reducing obesity a... | 02/15/2011 |
| 7887854 | Formulations containing and extracts which are useful in the treatment of obesity The present invention relates to a Cynara scolymus extract with a high content of caffeoylquinic acids, and a composition containing said Cynara scolymus extract with a Phaseolus vulgaris extract. Said composition is useful in reducing ob... | 02/15/2011 |
| 7795016 | P185 -encoding DNA and therapeutical uses thereof Plasmids containing sequences encoding different fragments of p185neu oncoprotein, able to induce an immune response against tumours expressing oncogenes of the ErbB family, and pharmaceutical compositions thereof. ... | 09/14/2010 |
| 7691422 | Oral compositions for the treatment of cellulite The present invention relates to oral pharmaceutical and cosmetic compositions for the treatment of cellulite containing Vitis vinifera extracts, Centella asiatica triterpenes and dimeric Ginkgo biloba flavonoids, in the free form or complexed w... | 04/06/2010 |
| 7687545 | N-deacetylthiocolchicine derivatives, their use and pharmaceutical formulations containing them Disclosed is a series of N-deacetylthiocolchicine derivatives of formula I in which: the linker is a bivalent straight or branched C1-C8 alkyl resi... | 03/30/2010 |
| 7683163 | Colchicoside analogues The present invention relates to colchicine derivatives, in particular to the 3-demethyl and 3-demethylthio-colchicine of the general formula (I) in which X is oxygen or sulfur, a method for the preparation thereof and pharmaceutical compositions containing them. Th... | 03/23/2010 |
| 7597915 | Compositions for the treatment of atopic dermatitis, skin allergic conditions and acne The present invention relates to topical compositions containing: a) Ginkgo biloba terpenes; b) floroglucinols pure or in mixture thereof, extracted from Humulus lupulus, Hypericum sp and Mirtus sp; c) Zanthoxylum bungeanum or Echinace... | 10/06/2009 |
| 7582639 | N-deacetylthiocolchicine derivatives, their use and pharmaceutical formulations containing them Disclosed is a series of N-deacetylthiocolchicine derivatives of formula I in which: the linker is a bivalent straight or branched C1-C8 alkyl residue, C3... | 09/01/2009 |
| 7582325 | Process for the preparation of tomato extracts with high content in lycopene A process for the extraction of lycopene from whole tomatoes, in which process tomatoes are heat concentrated and extracted with water-saturated ethyl acetate. ... | 09/01/2009 |
| RE40901 | Taxane derivatives and processes for the preparation thereof A novel taxane derivative with anticancer activity, a process for its preparation and a process for the preparation of 14-β-hydroxy-1,14-carbonate-baccatine III and V derivatives 13-substituted by an isoserine residue. ... | 09/01/2009 |
| 7579364 | N-deacetylthiocolchicine derivatives, their use and pharmaceutical formulations containing them Disclosed is a series of N-deacetylthiocolchicine derivatives of formula I in which: the linker is a bivalent straight or branched C1-C8 alkyl residue, C3... | 08/25/2009 |
| 7553502 | Formulations of alpha-amylase inhibitors with alpha-glucosidase inhibitors useful in the treatment of diabetes and obesity This invention relates to the combination of α-amylase inhibitors prepared from Phaseolus vulgaris with α-glucosidase inhibitors obtained from Salacia oblonga and other species. The α-amylase inhibitor is accompanied by a quantity of lectins that re... | 06/30/2009 |
| 7498452 | Taxane derivatives functionalized at the 14-position and a process for the preparation thereof A general process for the functionalization at the 14-position of 13-ketobaccatin derivatives of formula I to give derivatives of formula II wherein the substituents are as defined in the disclosure. The conversion of compounds of formula II in compounds of formula ... | 03/03/2009 |
| 7476392 | Pharmaceutical and/or cosmetic compositions for the treatment of localised adiposities and cellulite The present invention relates to pharmaceutical and/or cosmetic compositions containing a combination of the following active principles: a) complex of escin/beta-sitosterol with phospholipids, b) complex of Gingko biloba dimeric flavonoids with phospholipids... | 01/13/2009 |
| 7468438 | Process for the semisynthesis of deserpidine The present invention relates to an efficient procedure for the synthesis of deserpidine (Ia), starting from reserpic acid lactone (II) via the intermediate 11-O-demethyl reserpic acid lactone (III). ... | 12/23/2008 |
| 7465467 | Process for the extraction, purification and enzymatic modification of soy 7S globulin α' subunit for use as hypocholesterolemizing agent A process for the extraction, purification and enzymatic modification of β-conglycinin α′ subunit, wherein β-conglycinin is selectively extracted from ground, defatted soy, then precipitated by treatment with aqueous ethanol; the enriched fraction is then subje... | 12/16/2008 |
| 7446126 | Semisynthesis process for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel A process is provided for the preparation of 10-deacetyl-N-debenzoyl-paclitaxel (I) a synthon useful for the preparation of taxanes with antitumour activity, and intermediates for the preparation thereof. Also described is ... | 11/04/2008 |
| 7438934 | Formulations useful in the treatment of male and female impotence Pharmaceutical compositions containing: extracts of Tribulus terrestris, Epimedium koreanum, Cinnamon cassia in the weight ratio of 1.5-3.5:1-2:0.1-0.4 respectively; and optionally arginine or a physiologically equivalent ester, salt or precursor thereof. The... | 10/21/2008 |
| 7429673 | TRPV1 agonists, formulations containing them and uses thereof The compounds of the general formula (I) in which X is represents two hydrogen atoms, a π-bond, oxygen or methylene: R2 is a C6-C12 aryl, or arylalkyl residue: R3 is hydrogen, 2-hydroxyethyl or 2-aminoethyl are useful for the treatment of path... | 09/30/2008 |
| 7399788 | N-deacetylthiocolchicine derivatives, their use and pharmaceutical formulations containing them Disclosed is a series of N-deacetylthiocolchicine derivatives of formula (I) in which: the linker is a bivalent straight or branched C1-C8 alkyl residue, C3-C8 cycloalkyl, a phenylene or heterocyclic C4-C6 ... | 07/15/2008 |
| 7374748 | Pharmaceutical and cosmetic compositions for the protection of the skin from damages induced by sun radiations Pharmaceutical and cosmetic compositions for the protection of the skin from damages induced by sun radiations, containing ingredients of vegetable origin, in addition to conventional sun filters and excipients. ... | 05/20/2008 |
| 7371886 | Process for the preparation of ferutinine from genus plants The invention relates to a process for the preparation of ferutinine (Ia) from Ferula spp extracts comprising basic hydrolysis of the extracts and treatment with p-pivaloyloxybenzoic acid. The invention relates also to the use of the extracts and ferutinine i... | 05/13/2008 |
| 7361370 | Formulations useful in the treatment of male and female impotence Pharmaceutical compositions containing: extracts of Tribulus terrestris, Epimedium koreanum, Cinnamon cassia in the weight ratio of 1.5-3.5:1-2:0.1-0.4 respectively; and optionally arginine or a physiologically equivalent ester, salt or precursor thereof. The... | 04/22/2008 |
| 7354610 | Pharmaceutical and cosmetic composition against skin aging Pharmaceutical and cosmetic compositions for the prevention of skin aging, containing phospholipid complexes of extracts of Vitis vinifera, and phospholipid complexes of standardized extract from Centella asiatica. ... | 04/08/2008 |
| RE40120 | Process for the preparation of taxanes from 10-deacetylbaccatin III A process for the preparation of taxane derivatives by reacting 10-deacetylbaccatin III protected at the 7-and 1-positions with trichloroacetyl groups with a compound of formula and subsequent removal of the protective groups and... | 02/26/2008 |
| 7323441 | Use of lupin conglutin for the treatment of type II diabetes A method for the use of lupin conglutin gamma or of proteins showing homology higher than 50% with lupin conglutin gamma, for the preparation of a medicament, food supplements or foods for the treatment of type II diabetes, pharmaceutical and nutritional composition... | 01/29/2008 |
| 7317113 | Process for the preparation of the 14β-hydroxy-baccatin III-1,14-carbonate A process for the preparation of 14β-hydroxy-baccatin III-1,14-carbonate useful for the preparation of novel taxane derivatives with antitumor activity. ... | 01/08/2008 |
| RE39723 | Semi-synthetic taxanes with antitumor and antiangiogenetic activities Seco-baccatin III derivatives of formula: wherein R, R1-R4, R1 R′, R11 R″, and R111 R′″ are disclosed herein; pharmaceutical compositions comprising seco-baccatin ... | 07/10/2007 |
