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| Number | Title | Issue Date |
| 6051418 | Hybrid proteins with modified activity Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences... | 04/18/2000 |
| 5910481 | Hybrid proteins with modified activity Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences... | 06/08/1999 |
| 5869292 | Hybrid proteins with modified activity Hybrid proteins which affect blood coagulation comprise a region from a donor anticoagulant or antithrombotic protein, and the resulting hybrid protein has a modified biological activity. Information concerning the hybrid proteins implicates DNA sequences... | 02/09/1999 |
| 5863896 | Evaluation of substances for altering and for increasing APC response The present invention provides methods, reagents, and test kits for evaluating the effect of a test composition on APC response by employing factor VaR506Q Methods and compositions for treating patients suffering from reduced APC response are a... | 01/26/1999 |
| 5756341 | Method for controlling the infectivity of viruses A method for producing Influenza and other viruses and vaccines derived therefrom utilizes serum-free cultured vertebrate cells or vertebrate biomass aggregates to both eliminate the necessity to use costly methods requiring whole chicken embryos and, opt... | 05/26/1998 |
| 5698433 | Method for producing influenza virus and vaccine A method of producing an influenza virus and vaccines derived from the virus utilizes cultured vertebrate biomass aggregates comprising a plurality of cell types derived from a plurality of vertebrate tissues and is particularly suitable for use with chic... | 12/16/1997 |
| 5675058 | Bioassay for thrombogenesis and rabbit model An in vivo assay for determining the potential thrombogenic activity of a test compound entails pre-treating an animal with both a hepatoxin and either a bacterial agent (whole bacteria or bacterial toxins, including endotoxins) or a bacterial agent-induc... | 10/07/1997 |
| 5643739 | Assay for determining sensitivity to activated protein C An improved assay for determining sensitivity to activated protein C in test samples has been developed to ensure rapid and accurate evaluations. This assay is based on measuring the conversion, by activated factor VIII within a test sample, of added fact... | 07/01/1997 |
| 5614493 | Use of human protein C for prevention and treatment of depositions of thrombocytes The use of human Protein C for the prevention and treatment of deposition or aggregation of thrombocytes, microparticles of thrombocytes, and leucocytes is described. In addition, an improved method for the extra-corporeal treatment of body fluids is disc... | 03/25/1997 |
| 5478558 | Method of dissolving venous Thrombi using drug containing activated Protein C A method of dissolving venous thrombi using a thrombolytic, parenterally administrable drug containing activated protein C is described. The drug can be free of serum amyloid P, thrombin activity, infectious agents and antibodies against protein C and act... | 12/26/1995 |
| 5464396 | Syringe assembly for the storage and application of a biological multi-component material There is disclosed a syringe assembly for the storage and application of a biological multi-component material. Its assembly parts are a syringe device including several parallel syringe bodies interconnected by a connection part, which syringe bodies are... | 11/07/1995 |
| 5274081 | Complex suitable for carrying out a method of purifying pre-S hepatitis B surface antigen There is disclosed a complex comprised of an insoluble polymer carrier to which monomeric human albumin is covalently bound and of a pre-S hepatitis B surface antigen bound in an elutable form to the monomeric human albumin by its pre-S(2)- and/or pre-S(1... | 12/28/1993 |
