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| Number | Title | Issue Date |
| 7074610 | System and method of microdispensing and arrays of biolayers provided by same An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional features of the... | 07/11/2006 |
| 5821399 | Automatic test parameters compensation of a real time fluid analysis sensing device A method for automatic fluid flow compensation in disposable fluid analysis sensing devices is disclosed. The method is designed to keep the test conditions from sample to sample substantially unchanged. This is accomplished by using information about the... | 10/13/1998 |
| 5789253 | Methods for rapid equalibration of dissolved gas composition An apparatus and method of equilibrating the dissolved gas composition of an aqueous fluid to reflect the predetermined gas composition contained in a gas equilibration reservoir. The equilibrated aqueous fluid can be used in a method of determining the c... | 08/04/1998 |
| 5628961 | Apparatus for assaying viscosity changes in fluid samples and method of conducting same The present invention relates to an apparatus for conducting a variety of assays that are responsive to a change in the viscosity of a sample fluid and relates to methods of conducting such assays. In particular, the present invention is related to the us... | 05/13/1997 |
| 5614416 | Methods and apparatus for rapid equilibration of dissolved gas composition Disclosed is an apparatus and method of equilibrating the dissolved gas composition of an aqueous fluid to reflect the predetermined gas composition contained in a gas equilibration reservoir. The equilibrated aqueous fluid can be used in a method of dete... | 03/25/1997 |
| 5609824 | Methods and apparatus for rapid equilibration of dissolved gas composition Disclosed is an apparatus and method of equilibrating the dissolved gas composition of an aqueous fluid to reflect the predetermined gas composition contained in a gas equilibration reservoir. The equilibrated aqueous fluid can be used in a method of dete... | 03/11/1997 |
| 5593638 | Apparatus for estimating the change in an analyte from hemolysis in a fluid sample The present invention concerns a method of detecting hemolysis in a whole-blood sample, a method of determining an elevation in the potassium ion concentration of a whole-blood sample, an apparatus for detecting hemolysis and/or determining an elevation i... | 01/14/1997 |
| 5554339 | Process for the manufacture of wholly microfabricated biosensors An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional feat... | 09/10/1996 |
| 5514253 | Method of measuring gas concentrations and microfabricated sensing device for practicing same A microfabricated sensing device is disclosed, including methods for using the same for the measurement of the concentration of a gas in a sample. Unique sensor configurations are described which substantially eliminate electrode cross-contamination durin... | 05/07/1996 |
| 5466575 | Process for the manufacture of wholly microfabricated biosensors An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional feat... | 11/14/1995 |
| 5447440 | Apparatus for assaying viscosity changes in fluid samples and method of conducting same The present invention relates to an apparatus for conducting a variety of assays that are responsive to a change in the viscosity of a sample fluid and relates to methods of conducting such assays. In particular, the present invention is related to the us... | 09/05/1995 |
| 5416026 | Method for detecting the change in an analyte due to hemolysis in a fluid sample The present invention concerns a method of detecting hemolysis in a whole-blood sample, a method of determining an elevation in the potassium ion concentration of a whole-blood sample, an apparatus for detecting hemolysis and/or determining an elevation i... | 05/16/1995 |
| 5200051 | Wholly microfabricated biosensors and process for the manufacture and use thereof An efficient method for the microfabrication of electronic devices which have been adapted for the analyses of biologically significant analyte species is described. The techniques of the present invention allow for close control over the dimensional feat... | 04/06/1993 |
| 5124661 | Reusable test unit for simulating electrochemical sensor signals for quality assurance of portable blood analyzer instruments A reusable test unit is disclosed for testing the functionality of a portable blood analyzer, and particularly the interface between the high-impedance electrochemical sensors and the instrument. Signals are generated to simulate amperometric, conductimet... | 06/23/1992 |
| 5096669 | Disposable sensing device for real time fluid analysis A system comprising a disposable device and hand held reader can perform a variety of electrochemical measurements on blood or other fluids. In operation, a fluid sample is drawn into the disposable device through an orifice by capillary action. The orifi... | 03/17/1992 |
| 5063081 | Method of manufacturing a plurality of uniform microfabricated sensing devices having an immobilized ligand receptor A plurality of uniform microfabricated sensing devices are produced by establishing a plurality of base sensors on a substrate wafer, forming over at least a portion of each base sensor a permselective layer, superimposing a photoformable proteinaceous ph... | 11/05/1991 |
| 5009766 | Metal oxide electrodes An electrode for measuring the activity of ionic species. The electrode comprises a material which is chemically sensitive to at least one ionic species. The material comprises an insulating component and a conductive component of lower resistivity than t... | 04/23/1991 |
| 5008616 | Fluidics head for testing chemical and ionic sensors A fluidics head to facilitate the automatic testing of chemical and ionic sensing electronic circuit devices is provided. The fluidics head comprises a fluid confining cell having an open orifice capable of containing a known test fluid while the orifice ... | 04/16/1991 |
| 4954087 | Static-free interrogating connector for electric components An improved connector for connection to and identification and testing of electric components such as integrated circuits is described which features a number of spring biased contact elements normally in contacting relation with a shorting bar. When a pa... | 09/04/1990 |
| 4933048 | Reference electrode, method of making and method of using same An improved reference electrode is disclosed for use in potentiometric measurements of the amount of ions in an aqueous solution. The reference electrode illustratively comprises a metal member on a substrate, and a layer of a salt reversible to the ion X... | 06/12/1990 |
