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...that the inventor of the electric motor was a blacksmith named Thomas Davenport? Described as "a brilliantly unsuccessful inventor", Davenport invented the first rotary electric motor. In 1836 he headed out -- on foot -- from his Vermont home to file a patent application at the Patent Office in Washington, D.C. By the time he got there, he had squandered away his money and couldn't afford the $30 filing fee so he turned around and went home. When he later mailed in his application with money he'd raised, the Patent office was destroyed in a fire. He did finally get credit for his invention on Feb. 5, 1837.

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Assignee: Hisamitsu Pharmaceutical Co., Inc.


Location: Saga, JP
No. of patents: 85

1      
NumberTitleIssue Date
8173155Adhesive patch
The present invention relates an adhesive patch comprising a backing layer and an adhesive layer that contains a drug, wherein the adhesive layer contains a mixed adhesive base containing a hydrocarbon rubber and a silicon-containing polymer. The adhesive patch of t...
05/08/2012
7985556Method of screening apoptosis accelerating compound or anti-apoptotic compound and method of determining malignancy of neurodegenerative disease
Screening methods for determining pro-apoptotic compounds or anti-apoptotic compounds comprise measuring the interaction between p53 and NEDL1 in the presence and in the absence of a test compound, and comparing the strength of interaction between p53 and NEDL1 in t...
07/26/2011
7928144Antiinflammatory and analgesic preparation for external use
It is intended to provide an antiinflammatory and analgesic preparation for external use whereby side effects of a nonsteroidal antiinflammatory and analgesic drug on the skin can be regulated, the nonsteroidal antiinflammatory and analgesic drug can be prevented fr...
04/19/2011
7910792Patch having easily detachable release sheet
A patch permitting division of only its release sheet by simply pulling right and left, wherein detachment of the release sheet is easy. There is provided a patch comprising a stretchable support, a plaster applied substantially all over one major surface of the sup...
03/22/2011
7789733Method of manufacturing microneedle
A method of manufacturing a microneedle including the steps of forming a plurality of first linear grooves on a substrate in parallel to one another along a first direction using grinding, and forming a plurality of second linear grooves on the substrate in parallel...
09/07/2010
7759400Pressure-sensitive adhesive composition and skin patch
It is intended to provide a composition which has well-balanced pressure-sensitive adhesiveness and cohesive force as well as favorable application properties to the skin, and a patch which has the above-described characteristics and hardly peels off. This object ca...
07/20/2010
7718188Transdermal patch for external use comprising fentanyl
A transdermal patch for external use having a backing layer and a pressure-sensitive adhesive layer formed on one surface of the backing layer, which contains polyisobutylene, a mineral oil and fentanyl employed as the active ingredient in the pressure-sensitive adh...
05/18/2010
7625620Sheet-type patch
It is intended to provide a sheet-type patch which is safe to the skin, imparts a good feel in using, shows an excellent function as well as a cooling effect on the affected part, can be easily torn by hand into a desired size even in the state of a preparation prov...
12/01/2009
7618787Method of screening compound capable of accelerating or inhibiting apoptosis, apoptosis accelarator and apoptosis inhibitor
A method for screening a pro-apoptotic compound comprising a determination step of determining a compound enhancing interaction between p73 and IKK-α as a pro-apoptotic compound. ...
11/17/2009
7615237Percutaneously absorbable preparations
Percutaneously absorbable preparations (preferably nonaqueous ones, particularly matrix-type patches or ointment), containing salt-form acidic drugs and characterized by being improved in the percutaneous absorbability of the drug by the incorporation of an addition...
11/10/2009
7502654Electrode device having recessed part
The invention provides an electrode device that prevents disconnection of an electrode layer effectively by reducing stress at the time when a recess is formed. An electrode device (10) has a protrusion (70), which projects upward, in the part o...
03/10/2009
7335755Nucleic acids isolated in neuroblastoma
There are disclosed a nucleic acid whose expression is enhanced in human neuroblastoma with unfavorable prognosis based on comparison between human neuroblastoma with favorable prognosis and human neuroblastoma with unfavorable prognosis, the nucleic acid comprising...
02/26/2008
7250546Adhesive preparations
This invention provides a patch with less skin stimulation, excellent in long time store stability and heat stability and having favorable tack during use. The patch comprising a styrene-isoprene-styrene block copolymer, polyisobutylene, tackifier, plasticizer and p...
07/31/2007
7214782Nucleic acid of novel human kinesin-related gene protein encoded by the nucleic acid peptide fragment thereof and anticancer agents comprising the nucleic acid and the like
There are provided base sequence data for human kinesin-related genes with a motor domain, as well as information relating to the functions of the proteins encoded by the human kinesin-related gene and the motor domain-lacking human kinesin-related gene, which data ...
05/08/2007
7153522Sorbefacients and preparations for percutaneous absorption containing the same
Percutaneous sorbefacients comprising hexylene glycol and 1-menthol, more particularly, percutaneous sorbefacients for female hormones or derivatives thereof; and preparations for percutaneous absorption which comprise a styrene/isoprene/styrene block copolymer and/...
12/26/2006
7087223Preventives and/or remedies for hyperphosphatemia
Provided in a phosphate ion adsorbent containing a weakly basic anion exchange resin as an active ingredient which aims at providing preventives and/or remedies for hyperphosphatemia having a high selectivity for the adsorption of phosphate ion and showing an effect...
08/08/2006
7087383Nucleic acid sequences showing enhanced expression in benign neuroblastoma compared with acritical human neuroblastoma
There are disclosed a nucleic acid which is derived from the gene expressed in human neuroblastoma, and which comprises any sequence selected from the group consisting of the nucleic acid sequences set forth SEQ ID NO:1 to NO:104 in the Sequence Listing, or its comp...
08/08/2006
7064242Patch
A patch comprising a backing layer and a adhesive layer formed on the back face of the backing layer wherein a woven fabric or a nonwoven fabric made of a rayon and pulp fiber mixture is employed as the backing layer and the mixing ratio thereof is from 3:7 to 7:3. ...
06/20/2006
7045137Sheet-type packs
Sheet-type packs which exert a skin cleaning effect while maintaining an effect of appropriately moistening the skin and are excellent in the feel in using and safety to the skin. In particular, sheet-type packs containing fruit extracts. ...
05/16/2006
7034083Pressure-sensitive adhesive and patch employing the same
An adhesive which comprises aqueous and nonaqueous polymers suitable for holding an lipophilic drug, etc., and has tackiness and cohesiveness which are sufficient for the plaster of a patch; and a patch employing the adhesive. The adhesive contains a polymer which c...
04/25/2006
7018345Iontophoresis system
The present invention provides an iontophoresis system for non-invasively taking a physiological substance out of the living body, the system being suitably used for the mucous membrane. The present iontophoresis system non-invasively takes a physiological substance...
03/28/2006
7005784Electrode apparatus for preventing cracking of the electrode and insulating layers
It is an object of the invention to prevent not only cracking but also blocking of an electrode layer 20 and an electrically insulating layer 30, particularly the electrically insulating layer 30, which is formed on a base film 10. An ele...
02/28/2006
6991095Packaging bag for plaster and packaged plaster
Packaged patch (10) according to the invention comprises patch (2) situated in space (4) inside patch package (3) composed of laminated packaging material (1), and its edges are sealed. Laminated packaging material (1) compr...
01/31/2006
D512509Medical patch
12/06/2005
6970739Iontophoresis device
This is an iontophoresis device preferred to detect abnormal conductivity at the beginning of energization and during energization. The iontophoresis device has a device (50) as a power source and the device (50) comprises an electric energy generating...
11/29/2005
6964520Packaging bag
In a bag 10 for packaging having a first face 10A and a second face 10B that are mutually opposite, a first line of weakness 100A (100B) and a second line of weakness 200A (200B) and a third line of weakness 300
11/15/2005
D508208Container for spraying
08/09/2005
6915159Electrode structure for iontophoresis device and method of producing the same
The invention is to provide an electrode structure of an iontophoresis device and a method of producing the same, excellent in an economical property, an operational property, stability and safety. The electrode structure for the iontophoresis device comprises a bac...
07/05/2005
6914169Patch agent
The patch agent of the present invention is a patch agent comprising a support made of a synthetic fiber and an adhesive layer mounted on the support, and having a bending resistance of 10 to 30 mm and a probe tack value of 0.25 to 1.2 N. The patch agent of the pres...
07/05/2005
69003072-aminopurine derivatives
There are provided 2-aminopurine derivatives represented by the following general formula (1): where R represents any species selected from the group consisting of hydrogen and acyl groups, X represents any species sel...
05/31/2005
D501135Package
01/25/2005
6844372Crosslinked anion-exchange resin or salt thereof and phosphorus adsorbent comprising the same
An cross-linked anion exchange resin or a salt thereof obtained by reacting a polymer (A) having amino and/or imino groups in the total number of two or more per molecule with a compound (B) having two or more functional groups capable of reacting with amino and/or ...
01/18/2005
6844007Plaster containing felbinac
A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plas...
01/18/2005
6841716Patch
According to the invention, a patch provided with a support 1, an adhesive layer 2 laminated on one side of the support, and a release film 4 attached in a releasable manner to the adhesive layer and having a slit 42 running from one edge...
01/11/2005
6833138Plaster containing felbinac
A plaster comprising a styrene-isoprene-styrene block copolymer 10-40 wt %, a rosin-based resin 5-30 wt %, a plasticizer 20-70 wt %, polyisobutylene 6-40 wt %, an antioxidant 0.1-5 wt %, and felbinac as a medicinally effective component 1.1-10 wt %, wherein the plas...
12/21/2004
6815430Gene expression base sequences for therapeutic use and drugs for gene therapy
The base sequence for the expression of a therapeutic gene and the medicament for gene therapy are disclosed. There is also disclosed the base sequence for the expression of a therapeutic gene, said sequence being shown in any one of from (a) to (d) and capable of d...
11/09/2004
6760618Iontophoresis system
An iontophoresis system comprises a power supply apparatus having a chargeable battery, a positive output terminal, a negative output terminal and a positive charge terminal, and a preparation having input terminals connected to output terminals of the power supply ...
07/06/2004
6743432Interface for iontophoresis
A hydrophilic membrane having a low adsorptivity for a protein is disposed, as an interface, on a side to be contacted with a skin, and a drug such as a physiologically active peptide is transdermally delivered by iontophoresis. The membrane has an adsorptivity for ...
06/01/2004
6654635Iontophoresis device
An iontophoresis device, which can ensure the long-term stability of drugs and which can be easily assembled when used, is provided. A donor electrode-printed portion (6) is placed on one side of a backing layer (4), and a reference electrode-printed port...
11/25/2003
6643544Iontophoresis device
The present invention provides an iontophoresis device and an energization method whereby a prostaglandin can be effectively and continuously administered via a skin or mucosa. The iontophoresis device comprises the first electrode structure (31); the sec...
11/04/2003
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