Famous Patents
Pong, the Atari creation that launched the computer game craze, came with these instructions: "Avoid missing ball for high score."
PatentStorm News
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 5457098 | 17 yl 6 azaandrost-4,6 diazo-4-ene-3-ones There are disclosed preparation and compounds of formula (I): ##STR1## wherein R1 and R2 are hydrogen or lower alkyl or taken together are a --CH2 -- group to form a cyclopropane ring. X is ##STR2## wherein R | 10/10/1995 |
| 5442892 | System for facilitate recycling goods from defective packages on a blister packaging machine A pneumatic apparatus for withdrawing goods from defective blister packages on a blister packaging machine and comprising a pair of spaced-apart and laterally shiftable vacuum heads reciprocally mounted above the carrier strip between the detection statio... | 08/22/1995 |
| 5426196 | Synthesis of diaryl methanes The present Invention includes synthetic steps and intermediates involved in the following reaction scheme a of converting compounds of Formula (II) to the diarylmethanes of Formula (I): ##STR1## wherein: Y is oxygen or sulfur; A, B, C, D, and E are ... | 06/20/1995 |
| 5421492 | Metered aerosol dispensing apparatus and method of use thereof The present invention relates to an aerosol dispensing apparatus, more particularly to aerosol dispensing valves incorporating a controlled metered dispensing function wherein the metering chamber holding the next aerosolized dose is in fluidic communicat... | 06/06/1995 |
| 5415162 | Multi-dose dry powder inhalation device A breath-actuated dry powder medicament inhalator device having a housing and a conduit mounted within the housing defining an air passageway therethrough having an aperture in the sidewall thereof. A blister-type strip of sealed containers arranged in a ... | 05/16/1995 |
| 5407687 | Ranitidine solid dosage form The present invention comprises a bi-layer, pharmaceutical tablet having one layer formulated for the immediate release (IR) of ranitidine and a second layer formulated for sustained release (SR) of ranitidine with the ratio of ranitidine in the IR layer ... | 04/18/1995 |
| 5387688 | Intermediates for making analgesic N-phenyl-N-(3-OR1 -3-Me-4-piperidinyl)amides Novel piperidinyl intermediates as set forth below wherein R, R1 and Ar are as set forth in the specification and W is either hydrogen or benzyloxycarbonyl. The intermediates are useful in the preparation of N-phenyl-N-(4-piperidinyl) amides ha... | 02/07/1995 |
| 5380872 | Modulators of cholecystokinin CCK modulators, e.g. agonists or antagonists, of the following formula (I): ##STR1## or a base-addtion salt thereof.... | 01/10/1995 |
| 5376359 | Method of stabilizing aerosol formulations A method of making a stabilized aerosol drug formulation is disclosed, along with the formulations so produced and metered drug inhalers containing the same. The method comprises combining a solid particulate drug composition with a fluoropolymer in a liq... | 12/27/1994 |
| 5342947 | Preparation of water soluble camptothecin derivatives The present invention relates to the synthesis of water soluble, camptothecin derivatives of formula (I), ##STR1## wherein: n represents the integer 1 or 2; R1 represents independently, hydrogen, lower alkyl, (C3-7)cycloalkyl, (... | 08/30/1994 |
| 5329008 | Synthesis of a 3,4-dihydroxy-1-cyclopentanylpurinone Synthesis of the triol of the following formula (I) from an alcohol of the formula (IV): ##STR1## via steps including protecting and then cyanating the alcohol to yield a cyanide, isomerization of the double bond, hydrolysis followed by reductio... | 07/12/1994 |
| 5326760 | Aminobutanoic acid compounds having metalloprotease inhibiting properties Aminobutanoic acids of the following formula (I): ##STR1## where R1 -R5 are a variety of substituents, novel intermediates, a pharmaceutical composition for treating inflammatory diseases, demyelinating diseases, and tumor metas... | 07/05/1994 |
| 5318976 | Cyclic antitumor compounds The present invention relates to certain substituted tetracyclic fused quinoline derivatives of formula (I): ##STR1## wherein: R1 is hydrogen, hydroxy, fluoro, chloro, bromo, iodo, methoxy or amino; R2 is hydrogen, hydroxy, meth... | 06/07/1994 |
| 5318183 | Bottle with insert to reduce effective volume A bottle having an inserted tube in its neck to effectively reduce its interior volume and allow a large surface area for the bottle exterior, e.g. for supporting a large label or to allow oversized print, with a relatively small interior volume, e.g. to ... | 06/07/1994 |
| 5302589 | Heterocyclic inhibitors of 5--testosterone reductase The present invention relates to certain substituted 17 ଲ-substituted carbonyl-6-azaandrost-4-en-3-ones of formula (I): ##STR1## wherein R1 and R2 are i) independently hydrogen or lower alkyl and the bond between the carbons ... | 04/12/1994 |
| 5261538 | Aerosol testing method The present invention comprises a method for measuring the amount, i.e., mass, of a volatile liquid which comprises passing the mass over a heat loss measuring device, calculating the amount of heat loss accompanying the vaporization of the mass and corre... | 11/16/1993 |
| 5258519 | Dihydropyridine vasodilators agents Compounds of the following formula (I): ##STR1## where R1 and R2 are alkyl or cycloalkyl, which may be substituted, R4 is aryl such as phenyl which may be substituted, L is a direct bond or an oxygen containing linkin... | 11/02/1993 |
| 5252560 | Cyclic imide derivatives, compositions and use Compounds are described of the formula ##STR1## wherein: R1 is C3-6 alkyl or C1-3 alkylthioC1-3 alkyl; R2 is an optionally substituted C1-6 alkyl or C1-6 alkoxy group, aryl, hete... | 10/12/1993 |
| 5241069 | Carbonate intermediates for the synthesis of purine substituted cyclopentene derivatives This invention relates to the new process for preparing the 1R-cis isomer of carbovir, (1R-cis)-amino-1,9-dihydro-9-[4-(hydroxymethyl)-2-cyclopenten-1-yl]-6H-pur in-6-one, an antiviral agent and intermediates of the formula (Vlb) use in that process ... | 08/31/1993 |
| 5239993 | Dosage inhalator providing optimized compound inhalation trajectory A breath actuated dry powder medicament inhalator has a primary air passageway therethrough defining a venturi in the medial portion thereof. A secondary air passageway is provided which includes a compound deaggregating swirl chamber and is fluidly conne... | 08/31/1993 |
| 5223506 | Cyclic antitumor compounds The present invention relates to certain substituted tetracyclic fused quinoline derivatives of formula (I): ##STR1## wherein: R1 is hydrogen, hydroxy, fluoro, chloro, bromo, iodo, methoxy or amino; R2 is hydrogen, hydroxy, meth... | 06/29/1993 |
| 5217145 | Multiple product dispenser A multiple product dispenser for sequential dispensing of a first product in substantially its entirety and then a second product immediately thereafter from a dispenser by continuously rotating a thumb wheel at the bottom of the dispenser housing.... | 06/08/1993 |
| 5214148 | Analgesic N-phenyl-N-(3-OR1 -3-ME-4-piperidinyl)amides N-Phenyl-N-(4-piperdinyl)amide derivatives are disclosed having the general formula (I): ##STR1## wherein X, Ar, R and R1 are defined, including isomeric forms thereof and acid addition salts thereof. The compounds exhibit analgesic activi... | 05/25/1993 |
| 5204463 | Substituted methoxyphenyl-4,5 dihydro-3(2H)-pridazinones having cardiotonic and beta blocking activities Pyridazinones of the following formula (I): ##STR1## where R1 -R4 are a variety of substituents and L is a linking group, a pharmaceutical composition for treating congestive heart failure, novel intermediates, methods for such ... | 04/20/1993 |
| 5192757 | Cobalt porphyrins Cobalt prophyrins of the following formula (l): ##STR1## or a salt or ligand complex thereof and their synthesis, pharmaceutical compositions and use in controlling obesity.... | 03/09/1993 |
| 5187305 | S-nitroso-N-alkonoylpenicillamines The present invention relates to the compounds of formula (I), ##STR1## wherein R1 is C1-8 alkyl; C5-8 cycloalkyl;--(CH2)n --Si(CH3)3, wherein n is 1 to 5; C2-5 a... | 02/16/1993 |
| 5174475 | Sequential dosing of antifungal and antiinflammatory compositions A sequential dosing medicament for topical treatment of fungal infections comprising a first pharmaceutical composition having an antifungal agent and an antiinflammatory agent, e.g. a steroid, a second separate pharmaceutical composition having only an a... | 12/29/1992 |
| 5170801 | Medical capsule device actuated by radio-frequency (RF) signal A medical capsule device for releasing a substance at a defined location in the gastrointestinal tract. The device has a capsule body defining one or more apertures in the circumferential wall thereof and a sleeve valve rotatably positioned therein having... | 12/15/1992 |
| 5167626 | Medical capsule device actuated by radio-frequency (RF) signal A medical capsule device for releasing a substance at a defined location in the gastrointestinal tract. The device has a capsule body defining one or more apertures in the circumferential wall thereof and a sleeve valve rotatably positioned therein having... | 12/01/1992 |
| 5161524 | Dosage inhalator with air flow velocity regulating means A breath actuated inhalator having a primary and a secondary air flow conduit wherein regulator means are provided in the secondary air flow conduit to planate maximum air flow velocity through the inhaler. By optimizing air flow and velocity rate, the br... | 11/10/1992 |
| 5158194 | Safety closure with easy-open feature for handicapped and elderly individuals A child-resistant, two-piece closure is formed with a resilient wedge in the outer cap member which can be pressed into interlocking relationship with an upstanding locking lug element of the inner cap member to facilitate rotational movement in the closu... | 10/27/1992 |
| 5153209 | Pyridone nitriles useful in treating cardiovascular disease Pyridones of formula (I) for treating congestive heart failure: ##STR1## wherein: R1 and R2 are a variety of phenyl substituents, L is a divalent alkylene linking group. Pharmaceutical composition, methods for their use in treat... | 10/06/1992 |
| 5149697 | Cobalt porphyrin pharmaceutical compositions Pharmaceutical compositions containing cobalt porphyrins of the following formula (I): ##STR1## wherein R1 =--CH2 CH2 CN and R2 =--CH2 CH2 COOH or R1 and R2 =--CH... | 09/22/1992 |
| 5144034 | Process for the synthesis of cyclopentene derivatives of purines This invention relates to a new process for preparing certain optically active cyclopentene derivatives and novel intermediates used in this process. In particular, the invention concerns the synthesis of the 1'R-cis isomer of carbovir, (1'R-cis)-2-a... | 09/01/1992 |
| 5136085 | Synthesis of 2-aminobenzophenones Process for synthesizing 2-aminobenzophenones such as the following formula (I): ##STR1## wherein X1 and X2 are substituents and r and s are 1 or 2, by reacting an anthranilic acid amide e.g. an N-alkoxy-N-alkyl anthranilic ... | 08/04/1992 |
| 5130321 | Analgesic n-phenyl-n-(3-or 1-3-me-4-piperidinyl)amides N-Phenyl-N-(4-piperdinyl)amide derivatives are disclosed having the general formula (I): ##STR1## wherein X, Ar, R and R1 are defined, including isomeric forms thereof and acid addition salts thereof. The compounds exhibit analgesic activi... | 07/14/1992 |
| 5126351 | Antitumor compounds The present invention relates to the compounds of formula (I), ##STR1## wherein: R1 is hydrogen, hydroxy or amino; R2 is hydrogen, hydroxy, methoxy or methoxymethoxy; R3 is hydrogen, hydroxy, amino, methoxy, methoxymethyoxy, or... | 06/30/1992 |
| 5126123 | Aerosol drug formulations This invention relates to aerosol inhalation drug formulations comprising one or more drugs and one or more soluble surfactants in propellant 134a.... | 06/30/1992 |
| 5119806 | Inhalation device A device for dispensing an aerosol from an aerosol module containing aerosol under pressure wherein there is a cocking device for readying it for release of the pressurized aerosol, a sear for retaining the cocking device in a non-operative position follo... | 06/09/1992 |
| 5096904 | Pyridazinones having cardiotonic and beta blocking activities Pyridazinones of the following formula (I): ##STR1## where R1 -R4 are a variety of substituents and L is a linking group, a pharmaceutical composition for treating congestive heart failure, novel intermediates, methods for such ... | 03/17/1992 |
