Assignee: Glaxo Group Limited (GB2)

Location: Not specified.
No. of patents: 26

Browse patents
Browse applications

Number	Title	Issue Date
6238929	Systems and methods for the synthesis of organic compounds The invention provides systems and methods for synthesizing various compounds on solid support. According to one exemplary method, a synthesizer is provided having at least one reaction vessel block with a plurality of reaction vessels therein. At least o...	05/29/2001
5019586	Ketone derivatives The present invention provides ketones of the general formula (I): ##STR1## and physiologically acceptable salts and solvates thereof, wherein R1 and R2, which may be the same or different, each represents a hydrogen atom or a C...	05/28/1991
4822881	Tetrahydro carbazolone intermediates The invention relates to compounds of the general formula (I): ##STR1## wherein Im represents an imidazolyl group of the formula: ##STR2## and the various substituents are defined hereinbelow. The compounds are potent and selective antagonists o...	04/18/1989
4816470	Heterocyclic compounds Indole derivatives of the general formula (I) are disclosed: ##STR1## where R1 is H or an alkyl or alkenyl group, R2 is H, or an alkyl, alkenyl, aryl, aralkyl or cycloalkyl group; R3 is H or an alkyl group; R4 a...	03/28/1989
4814344	Indole derivatives The invention relates to compounds of formula (I) ##STR1## wherein R1 represents a hydrogen atom or a group selected from C1-10 alkyl, C3-6 alkenyl, C3-10 alkynyl, C3-7 cycloalkyl, C3-7	03/21/1989
4808581	Imidazolyl- indolylpropanones as 5-HT₃ receptor antagonists The invention relates to compounds of formula (I): ##STR1## and physiologically acceptable salts or solvates thereof, wherein Im represents an imidazolyl group of formula: ##STR2## and the various substituents are defined hereinbelow. The compou...	02/28/1989
4764612	3-[3-[1-piperidinylmethyl]phenoxy]propanamine The invention relates to compounds of the general formula (I) ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which the variables are as defined in the specification. The compounds of formula (I) show pharmacological ...	08/16/1988
4753789	Method for treating nausea and vomiting The invention relates to the use of compounds of the general formula (I) ##STR1## wherein R1 represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycoalkyl-(C1-4) alkyl, C3-6 ...	06/28/1988
4749718	Carbazole derivatives and their use as 5HT-induced antagonists The invention relates to compounds of the general formula (I): ##STR1## wherein R1 represents a group CO2 R5, COR5, CONR5 R6 or SO2 R5 (wherein R5 and R	06/07/1988
4725615	Carbazole derivatives and their use as 5HT-induced antagonists The invention relates to compounds of the general formula (I): ##STR1## wherein R1 represents a hydrogen atom or a C1-10 alkyl, C3-7 cycloalkyl, C3-7 cycloalkyl-(C1-4)-alkyl, C3-6 alke...	02/16/1988
4650800	Substituted pyrimidin-2-ones, the salts thereof, pharmaceutical compositions containing them and a method therefor Compounds of the general formula: ##STR1## wherein X represents a halogen atom or a trifluoromethyl group; R1 represents a hydrogen atom or a lower alkyl group and Het represents an optionally substituted C-attached 5-7 membered aromatic h...	03/17/1987
4650810	Indole-5-acetamides for treatment of migraine Compounds are disclosed of general formula (I): ##STR1## wherein R1, R3, R4, R6 and R7, which may be the same or different, each represents a hydrogen atom or an alkyl group; R2 represents ...	03/17/1987
4636509	Substituted pyrimidin-2-ones, the salts thereof, processes for their preparation, pharmaceutical compositions containing them and a method therefor Compounds of the general formula: ##STR1## (wherein X represents a halogen atom or a trifluoromethyl group; R1 represents an optionally substituted C6-10 carbocyclic aromatic group; and R2 represents a hydrogen atom o...	01/13/1987
4578221	Androstane carbothioic acids Androstane carbothioic acids of the formula: ##STR1## wherein R1 represents a hydrogen atom, a hydroxy group in the ଱-configuration, a methyl group which may be in either the ଱- or ଲ-configuration, or a methylene group; R...	03/25/1986
4564618	5-Halovinyl-2'-deoxyuridine derivatives Compounds of general formula (I): ##STR1## wherein R is a chlorine, bromine or iodine atom and physiologically acceptable salts thereof with bases of use as antiviral agents....	01/14/1986
4481199	1,2,4-Triazole-3-amine and 1,2,4 triazole-3,5-diamine compounds and their pharmaceutical use The invention provides compounds of the general formula (I) ##STR1## and physiologically acceptable salts, hydrates and bioprecursors thereof, in which the substituents are defined later. The compounds show pharmacological activity as selective histamine ...	11/06/1984
4447428	Prostanoid compounds and pharmaceutical compositions Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH--or --(CH2)2 ...	05/08/1984
4410521	Aminocyclopentane esters and pharmaceutical formulations Compounds are described of the formula ##STR1## in which --COR1 is a complex ester or thioester group, W is alkylene, X is cis or trans --CH.dbd.CH or --CH2 CH2 --, n is 1 or 2, Y is a saturated heterocyclic amino group having ...	10/18/1983
4409213	Prostanoid compounds and pharmaceutical compositions Prostanoid compounds are described having the formula: ##STR1## where A is a cyclopentane ring, which is substituted by oxo and/or hydroxy or etherified hydroxy and may be saturated or unsaturated; X is --CH.dbd.CH-- or --(CH2)2...	10/11/1983
4379920	Cephalosporins Cephamycin compounds of the formula (I) ##STR1## wherein R1 represents hydroxyl or sulphooxy and R2 represents sulphooxy together with derivatives thereof including salts, esters, N-protected derivatives and solvates thereof are...	04/12/1983
4374983	Intermediates for use in the preparation of cephalosporin antibiotics (6R,7R)-7-amino-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylic acid monoperchlorate is a useful intermediate in the preparation of (6R,7R)-7-amino-3-(1-pyridiniummethyl)ceph-3-em-4-carboxylate dihydrochloride by enzymatic deacylation of 7-amino-3-(1-pyridin...	02/22/1983
4342756	Aminocyclopentane alkenoic acids and esters and pharmaceutical compositions Compounds are described of the formula ##STR1## (and their salts and solvates) in which: X is cis or trans --CH.dbd.CH--; R1 is C1-7 alkyl terminated by --COOR3 where R3 is H, C1-6 alkyl or C7-10...	08/03/1982
4327092	Aminocyclopentane alkenoic acids and esters and pharmaceutical formulations Compounds are described of the formula ##STR1## (and their salts and solvates) in which: X is cis or trans --CH.dbd.CH--; R1 is C1-7 alkyl terminated by --COOR3 where R3 is H, C1-6 alkyl or C7-10...	04/27/1982
4298732	Crystallization process A process for the preparation of crystalline sodium cefuroxime (the sodium salt of (6R,7R)-3-carbamoyloxymethyl-7-[(Z)-2-(fur-2-yl)-2-methoxyimino-acetamido] ceph-3-em-4-carboxylic acid) which comprises adding an aqueous solution of sodium cefuroxime ...	11/03/1981
4291059	Cycloaliphatic compounds, analgesic compositions thereof and method of use thereof as analgesics Compounds are disclosed of general formula (I) ##STR1## in which R1 represents a hydrogen atom, a halogen atom or a group OR2, in which R2 represents a hydrogen atom, an alkyl group or an acyl group, R3 rep...	09/22/1981
4277601	Preparation of sodium cefuroxime A process for the preparation of the sodium salt of the antibiotic (6R,7R)-3-carbamoyloxymethyl-7-[Z-2-(fur-2-yl)-2-methoxyiminoacetamido]-ce ph-3-em-4-carboxylic acid (cefuroxime) which comprises subjecting a corresponding 3-N-protected carbamoyloxymethyl...	07/07/1981

PatentStorm

Bizarre Patents

PatentStorm News

Assignee: Glaxo Group Limited (GB2)