Assignee: Gesellschaft fuer Biotechnologische Forschung mbH

Location: Braunschweig, DE
No. of patents: 23

Number	Title	Issue Date
7115269	Attenuated strain used as a vehicle for oral immunization The present invention is directed to an attenuated Salmonella comprising a eukaryotic expression vector for delivery of the eukaryotic expression vector to a eukaryotic cell. Delivery may be to eukaryotic cells cultured in vitro or to cells in vivo, such as b...	10/03/2006
6995005	Enzyme which cleaves ester groups and which is derived from The invention relates to an ester-group-cleaving enzyme obtainable by culturing the microorganism Thermomonospora fusca in a suitable nutrient medium, optionally in the presence of an inducer. ...	02/07/2006
6992235	Method for marker-free repetitive DNA expression cassette exchange in the genome of cells or parts of cells The invention relates to a method for marker-free DNA expression cassette exchange in the genome of cells or parts of cells by using the FLP recombinase mediated cassette exchange. A first DNA expression cassette carrying a positive-negative selection marker flanked...	01/31/2006
6900160	Triazolo-epothilones The invention relates to triazolo-thiazole analogues of epothilone A and epothilone B. ...	05/31/2005
6878545	Method for separating viable cells from cell suspensions The invention relates to a method of separating viable cells from cell suspensions using hydrocyclones, which method can, especially, be carried out continuously. ...	04/12/2005
6878534	Continuous fermentation process which is useful for the simultaneous optimal production of propionic acid and vitamin B12 The present invention relates to a fermentation process which is useful for the simultaneous production of propionic acid and vitamin B12, characterized in that it employs the culturing, on a suitable culture medium, of at least one microorganism suitable...	04/12/2005
6720161	Immobilized substrate, separation gels and method for detecting enzymatic activity The present invention refers to a method for attaching substrate molecules to gel matrices, characterized in that a substrate is covalently bound to a monomeric or oligomeric constitutional unit of a gel and the resultant product is polymerized. The present inventio...	04/13/2004
6706524	Method of improving the primary energy metabolism of mammalian cell lines The invention relates to a method of improving the primary energy metabolism of mammalian cell lines, in which by means of genetic engineering a structural gene for a cytoplasmic yeast pyruvate carboxylase is inserted into the mammalian cells and expressed. ...	03/16/2004
6573242	Dihydroxypropyl cysteine peptide and agent containing this peptide The invention relates to a S-(2,3-dihydroxypropyl)-cysteine peptide which has two long-chain fatty acids bonded in the form of esters at the dihydroxypropyl group, and which has the following sequence: Dhc GN NDE SNI SFK EK (SEQ ID No 1) ...	06/03/2003
6060273	Multicistronic expression units and their use Multicistronic expression units allow the equimolar expression of the genes located in the corresponding cistrons. These expression units are particularly suitable for the recombinant production of proteins composed of two or more polypeptide subunits....	05/09/2000
5622979	Thiangazole, its preparation, compositions and use thereof The invention relates to compounds of the following general formula I ##STR1## especially the compound of formula Ia referred to as thiangazole ##STR2## their pharmaceutically acceptable acid addition salts, processes for their preparation and t...	04/22/1997
5604249	Thiangazole, its preparation, compositions and use thereof The invention relates to compounds of the following general formula I ##STR1## especially the compound of formula Ia referred to as thiangazole ##STR2## their pharmaceutically acceptable acid addition salts, processes for their preparation and t...	02/18/1997
5480790	Water-soluble proteins modified by saccharides A water-soluble protein conjugate modified by saccharides is covalently bound to a carbohydrate backbone via a saccharide group. Such protein conjugates modified by saccharides can be produced in a simple way by polymerizing a vinylsaccharide and conjugat...	01/02/1996
5453372	Stabilized enzymes and process for preparing them Enzymes stabilized against the destabilizing effect of ionic surfactants and a method of producing such stabilized enzymes in which DNA sequences which code for the enzymes are modified by directed mutation in defined positions which correlate with define...	09/26/1995
5352603	Highly alkaline proteases Novel, optimized highly alkaline proteases which are suitable for use in detergent formulations are prepared by employing microorganisms transformed by mutated DNA sequences. The mutated sequences are obtained starting from DNA sequences which code for hi...	10/04/1994
5338681	Method of isolating polysaccharide producing bacteria from non-polysaccharide producing bacteria with gellan The invention relates to a method for isolating a polysaccharide extracellularly producing bacteria from a mixed culture of non-polysaccharide and polysaccharide producing bacteria, The method uses a streaking technique on a nutrient medium containing uns...	08/16/1994
5254467	Fermentive production of 1,3-propanediol A process for the transformation of glycerol into 1,3-propanediol by microorganisms comprising fermenting the microorganisms in media having a glycerol content of from about 5% to about 20% by weight under standard anaerobic fermentation conditions and re...	10/19/1993
5147929	Process for mild esterification of a carboxylic acid with an alcohol component The invention relates to a process for mild esterification of a sensitive carboxylic acid, in particular a suitably protected amino acid, with an alcohol component, the esterification according to the invention being carried out in the presence of 2,...	09/15/1992
5114839	Process for DNA sequencing using oligonucleotide bank A process for DNA sequencing by the multi-primer method involving the use of oligonucleotide banks of hexamers, heptamers, octomers, or nonamers for the creation of the primer through the ligation of two or more oligomers following hybridization onto the ...	05/19/1992
5093358	Macrocyclic plant acaricides Compounds of the formula I ##STR1## in which either R is methyl and there is a double bond in the 9,10-position, or in which R is hydrogen and there is a single bond in the 9,10-position, are highly active against Acarina which damage plants....	03/03/1992
5023184	Antibiotics from myxococcus The invention relates to novel polycyclic alkaloids of formula ##STR1## in which R1 represents hydrogen or hydroxy, R2 represents hydrogen or acyl and A and B, independently of one another, each represents C.dbd.O or C--OH, and ...	06/11/1991
4432921	Process for producing a binder for wood materials A process in which phenolic substances, particularly lignin sulfonate, are used to produce a binder for wood materials. The phenolic substance is activated by displacing it with enzymes. Phenolic groups of the phenolic substance become oxidatively polymer...	02/21/1984
4284509	Process for removing oils or petroleum from the surface of the sea After physical removal of the majority of the oil on the surface of the water, the thin film remaining is treated with microbial metabolites which reduce the surface and interface tension and cause the formation of oil agglomerates. These agglomerates may...	08/18/1981

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Assignee: Gesellschaft fuer Biotechnologische Forschung mbH