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Assignee: Genzyme Corporation


Location: Boston, MA
No. of patents: 12

NumberTitleIssue Date
5942634Cationic amphiphiles for cell transfections
Cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with ...
08/24/1999
5925628Cationic amphiphiles for intracellular delivery of therapeutic molecules
Cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with ...
07/20/1999
5912239Imidazole-containing cationic amphiphiles for intracellular delivery of therapeutic molecules
Cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. There are provided also therapeutic compositions prepared typically by contacting a dispersion of one or more cationic amphiphiles with ...
06/15/1999
5910487Cationic amphiphiles and plasmids for intracellular delivery of therapeutic molecules
Novel cationic amphiphiles are provided that facilitate transport of biologically active (therapeutic) molecules into cells. The amphiphiles contain lipophilic groups derived from steroids, from mono or dialkylamines, or from alkyl or acyl groups; and cat...
06/08/1999
5856137Nucleic acids encoding and recombinant production of the ଲ subunit of lutenizing hormone
Biologically active heterodimeric human fertility hormones composed of two different subunits, each subunit being synthesized in the same cell transformed by at least one cell expression vector having heterologous DNA encoding each subunit with each subun...
01/05/1999
5639639Recombinant heterodimeric human fertility hormones, and methods, cells, vectors and DNA for the production thereof
Biologically active heterodimeric human fertility hormones composed of two different subunits, each subunit being synthesized in the same cell transformed by at least one cell expression vector having heterologous DNA encoding each subunit with each subun...
06/17/1997
5639640DNA encoding the beta subunit of human follide stimulating hormone and expression vectors and cells containing same
The correct sequence is disclosed for the beta subunit of human follicle stimulating hormone which, when present in a recombinant heterodimeric human fertility hormone allows the production of biologically active hormone. DNA coding for such beta subunit ...
06/17/1997
5156957Follicle stimulating hormone
Biologically active heterodimeric human FSH composed of an alpha subunit and a beta subunit, each subunit being synthesized by a cell having an expression vector containing heterologous DNA encoding the subunit....
10/20/1992
4937270Water insoluble derivatives of hyaluronic acid
A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel. Also, a method f...
06/26/1990
4923810Resolution of glycidyl esters to high enantiomeric excess
A method of resolving glycidyl esters to high enantiomeric excess involves fractionation of hydrolytic enzymes (e.g. lipases) to prepare biocatalysts with high enantioselectivity, and using these catalysts to selectively hydrolyze one enantiomer of the gl...
05/08/1990
4794078Alpha amylase assay
Method of measuring the amount of ଱-amylase in a liquid sample, including the steps of providing an oligosaccharide substrate for ଱-amylase, the substrate being characterized in that it contains at least 3 glucose units, its reducing-end gluco...
12/27/1988
4649108Alpha amylase assay
Method of measuring the amount of ଱-amylase in a liquid sample, including the steps of providing an oligosaccharide substrate for ଱-amylase, the substrate being characterized in that it contains at least 3 glucose units, its reducing-end gluco...
03/10/1987
 
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