Assignee: Genencor International, Inc.

Location: Palo Alto, CA
No. of patents: 164

Number	Title	Issue Date
7968318	Process for conversion of granular starch to ethanol A method is disclosed for producing glucose from a granular starch substrate including, contacting a slurry comprising granular starch obtained from plant material with an alpha-amylase at a temperature below the starch gelatinization temperature of the granular sta...	06/28/2011
7858762	Phosphate limited inducible promoter and a expression system An evolvable production strain of B. subtilis exhibiting continuous or high level expression during protein evolution is described. An evolved Bacillus subtilis pstS promoter facilitates screening and production of secreted proteins. ...	12/28/2010
7803591	Multimeric oxidoreductases Described are multimeric oxidoreductase complexes which function in the enzymatic conversion of a carbon substrate. The complexes having a dehydrogenase subunit and a cytochrome C subunit. Also described are polynucleotides coding for the multimeric complexes and me...	09/28/2010
7745189	Regulatable growth of filamentous fungi The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemica...	06/29/2010
7723079	glucoamylase and homologs thereof The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for ...	05/25/2010
7691806	Repeat sequence protein polymer active agent congjugates, methods and uses Biomolecular conjugates are provided which comprise the conjugation product of a repeat sequence protein polymer and at least one active agent. Additional aspects provide methods for their manufacture and various industrial and consumer applications. ...	04/06/2010
7642077	Biocomposite comprising co-precipitate of enzyme, silicate and polyamine This invention relates to a method of immobilizing biocatalysts including protein and cells by co-precipitation with silicate or organosilicate matrices through the action of an organic template molecule. The organic template molecule is in general a polyamine such ...	01/05/2010
7638613	Xylanase, microorganisms producing it, DNA molecules, methods for preparing this xylanase and uses of the latter The invention relates to a xylanase originating from a Bacillus strain. This xylanase is active over a wide range of acid and basic pH. The invention also relates to new strains of microorganisms producing this xylanase and to methods for preparing thi...	12/29/2009
7638073	Photochromic material comprising a proteorhodopsin apoprotein and a retinal analog The present invention relates to a photochromic material comprising a proteorhodopsin apoprotein and a retinal analog. In one embodiment, the retinal analog is an azulenic retinoid compound. In another embodiment, the retinal analog is a compound that is structurall...	12/29/2009
7629451	Acid fungal proteases The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and ...	12/08/2009
7626004	Protein purification The present invention relates to a method of purifying a protein of interest from its fusion analog, comprising obtaining a protein solution comprising a protein of interest and its fusion analog; adjusting the pH and/or ionic strength of the protein solution with a...	12/01/2009
7604974	029cel cellulase The present invention provides a novel cellulase nucleic acid sequence, designated 029cel, and the corresponding 029cel amino acid sequence. The invention also provides expression vectors and host cells comprising a nucleic acid sequence encoding 029cel, recombinant...	10/20/2009
7592420	Expression in filamentous fungi of protease inhibitors and variants thereof Described herein are protease inhibitors, variants thereof and methods for their production. ...	09/22/2009
7592157	Expression in filamentous fungi of protease inhibitors and variants thereof Described herein are protease inhibitors, variants thereof and methods for their production. ...	09/22/2009
7566448	Reduced aerosol generating formulations The present invention relates to compositions comprising high molecular weight polymers, particularly polyethylene oxide polymers, wherein the high molecular weight polymer serves as an anti-misting agent to reduce the potential of aerosol generation from a composit...	07/28/2009
7563609	Mutant 2,5-diketo-L-gluconic acid reductases Described herein are novel nucleic acids, proteins and methods that can be used to provide new catalysts with desirable traits for industrial processes. In particular, novel reductases isolated from the environment using PCR methods are described. ...	07/21/2009
7563607	Acid fungal protease in fermentation of insoluble starch substrates The invention is directed to methods of producing ethanol and decreasing residual starch production in a no cook fermentation comprising contacting granular starch containing substrates with a granular starch hydrolyzing enzyme, a protease, and a fermenting microorg...	07/21/2009
7544490	Secretion, transcription and sporulation genes in The present invention relates to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms having exogenous nucleic acid sequences introduced t...	06/09/2009
7544489	Secretion, transcription and sporulation genes in The present invention relates to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms having exogenous nucleic acid sequences introduced t...	06/09/2009
7544488	Secretion, transcription and sporulation genes in The present invention relates to cells that have been genetically manipulated to have an altered capacity to produce expressed proteins. In particular, the present invention relates to Gram-positive microorganisms having exogenous nucleic acid sequences introduced t...	06/09/2009
7524816	Peptides and supported peptides for treating skin diseases The present invention provides peptides and supported peptides for treating proliferative diseases. In particularly preferred embodiments, the present invention provides peptides and supported peptides for treating diseases of the skin, such as rosacea. In some part...	04/28/2009
7510831	phytase enzymes, nucleic acids encoding such phytase enzymes, vectors and host cells incorporating same and methods of making and using same A novel DNA is provided which encodes an enzyme having phytase activity isolated from Trichoderma. Also provided for is a method of isolating DNA encoding an enzyme having phytase activity from organisms which possess such DNA, transformation of the DNA into ...	03/31/2009
7501488	Proteorhodopsin mutants with improved optical characteristics The present invention is directed to a proteorhodopsin mutant having improved optical characteristics. One improved optical characteristic is having a lower pH (pKrh) at which equal concentrations of the acidic and basic spectral form of the proteorhodops...	03/10/2009
7498159	Heterologous alpha amylase expression in The present invention relates to the co-expression and production of a heterologous alpha amylase and an endogenous glucoamylase in an Aspergillus strain and enzyme compositions including the same. ...	03/03/2009
7494685	Trichoderma reesei glucoamylase and homologs thereof The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for ...	02/24/2009
7485618	FGF-5 supported and binding peptides The present invention provides peptides and supported peptides that bind to FGF-5. ...	02/03/2009
7476528	Proteins producing an altered immunogenic response and methods of making and using the same The present invention relates to novel protein variants that exhibit reduced allergenicity when compared to the parental proteins. Also included are DNA molecules that encode the novel variants, host cells comprising the DNA and methods of making proteins less aller...	01/13/2009
7456298	Synthesis of acetonides from aryl silanes The present invention is related to cis-diols and biological methods of producing cis-diols. The present invention further relates to processes for subsequently converting such silane cis-diols to the more stable acetonide derivatives, as well as a process for conve...	11/25/2008
7456147	Controlled release of active agents utilizing repeat sequence protein polymers Systems are provided for the controlled release delivery of active agents through the use of repeat sequence protein polymers. The systems may exist as matrices, gels, hydrogels, films, emulsions or microparticles and are particularly useful for incorporating active...	11/25/2008
7455998	Methods for forming structurally defined organic molecules Methods of forming organic molecules comprising contacting a hydrolase enzyme with an organic reactant are provided. Methods for forming an organosilicon molecule comprising contacting a hydrolase enzyme with an organosilicon reactant are also provided. ...	11/25/2008
7453023	Manipulation of the phenolic acid content and digestibility of plant cell walls by targeted expression of genes encoding cell wall degrading enzymes Described herein are methods to enhance the production of more highly fermentable carbohydrates in plants, especially forage grasses. The invention provides for transgenic plants transformed with expression vectors containing a DNA sequence encoding ferulic acid est...	11/18/2008
7449320	Truncated forms of pullulanase The present invention relates to modified pullulanases useful in the starch industry. The present invention provides methods for producing the modified pullulanase, enzymatic compositions comprising the modified pullulanase, and methods for the saccharification of s...	11/11/2008
7449317	Phytase enzymes, nucleic acid sequences encoding phytase enzymes and vectors and host cells incorporating same DNA is provided which encodes an enzyme having phytase activity isolated from Penicillium, Fusarium, Humicola and Emericella. Also provided for is a method of isolating DNA encoding an enzyme having phytase activity from organisms which possess such DN...	11/11/2008
7429476	Acid fungal proteases The present invention is directed to novel acid proteases and more specifically to NSP24 family proteases and NSP25 family proteases including biologically active fragments thereof and to nucleic acid molecules encoding said proteases. Also provided are vectors and ...	09/30/2008
7429475	Phytase enzymes, nucleic acid sequences encoding phytase enzymes and vectors and host cells incorporating same DNA is provided which encodes an enzyme having phytase activity isolated from Penicillium, Fusarium, Humicola and Emericella. Also provided for is a method of isolating DNA encoding an enzyme having phytase activity from organisms which possess such DN...	09/30/2008
7425450	Regulatable growth of filamentous fungi The present invention generally relates to hyphal growth in fungi and in particular describes the modulation of genes associated with hyphal growth in filamentous fungi. The present invention provides methods and systems for the production of proteins and/or chemica...	09/16/2008
7413879	glucoamylase and homologs thereof The present invention is related to glucoamylases having at least 80% sequence identity to a Trichoderma glucoamylase having the sequence of SEQ ID NO: 4 and biologically functional fragments thereof. The invention is also related to DNA sequences coding for ...	08/19/2008
7413877	Bacterial expression of bowman-birk protease inhibitors and variants thereof The present invention provides compositions and methods related to the expression of Bowman-Birk protease inhibitors and variants thereof in bacterial species. The present invention further provides fusion nucleic acids, vectors, fusion polypeptides, and processes f...	08/19/2008
7407791	Production of secreted polypeptides Described herein are methods and compositions for the production and secretion of polypeptides. Included herein is the use of interrupting peptide transport activity for an increase in polypeptide production and/or secretion. ...	08/05/2008
7407780	Process for producing glycerol in recombinant bacterial host cells The invention provides methods for producing products comprising improved host cells genetically engineered to have uncoupled productive and catabolic pathways. In particular, the present invention provides host cells having a modification in nucleic acid encoding a...	08/05/2008

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Assignee: Genencor International, Inc.