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| Number | Title | Issue Date |
| 7300779 | Preparation of a granule containing protein, corn starch and sugar layered on an inert particle Granules that include a protein core are described. The protein core includes a protein matrix which includes a protein mixed together with a starch. The protein matrix can be layered over a seed particle or the protein core can be homogeneous. The protein can be an... | 11/27/2007 |
| 6673590 | Multiply-substituted protease variants with altered net charge for use in detergents Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occ... | 01/06/2004 |
| 6642031 | Microorganisms with ability to degrade indole and enzymes therefrom There is provided novel indole oxidase activity isolated from P. putida, such indole oxidase activity is believed to be useful in the biosynthetic production of indigo from its precursor indole. Also provided are compositions of matter comprising the indo... | 11/04/2003 |
| 6599722 | Method for producing ascorbic acid intermediates The present invention relates to non-fermentative methods for the production of ASA intermediates, KDG, DKG and KLG and methods for the regeneration of co-factor. The invention provides genetically engineered host cells comprising heterologous nucleic aci... | 07/29/2003 |
| 6586221 | Subtilisin variants multiply-substituted subtilising variants having a substitution at position 76 Novel carbonyl hydrolase variants derived from the DNA sequences of naturally-occurring or recombinant non-human carbonyl hydrolases are disclosed. The variant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA seque... | 07/01/2003 |
| 6558933 | Mutant 1,3-propanediol dehydrogenase The present invention relates to mutant 1,3-propanediol dehydrogenase and a novel microorganism that is capable of growing in concentrations of at least 105 g/l 1,3-propanediol, levels normally toxic to wild-type microorganisms. The present invention also... | 05/06/2003 |
| 6528255 | Proteases from gram positive organisms The present invention relates to the identification of metalloproteases in gram positive microorganisms and provides the nucleic acid and amino acid sequences for a metalloprotease. Host cells having a mutation or deletion of part or all of the gene encod... | 03/04/2003 |
| 6489108 | Proteases from gram positive organisms The present invention relates to the identification of novel metalloproteases in gram positive microorganisms. The present invention provides the nucleic acid and amino acid sequences for the metalloprotease. The present invention also provides host cells... | 12/03/2002 |
| 6482628 | Multiply-substituted protease variants Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occ... | 11/19/2002 |
| 6468773 | Mutant 1,3-propandiol dehydrogenase The present invention relates to mutant 1,3-propanediol dehydrogenase and a novel microorganism that is capable of growing in concentrations of at least 105 g/l 1,3-propanediol, levels normally toxic to wild-type microorganisms. The present invention also... | 10/22/2002 |
| 6436696 | Enzyme treatment to enhance wettability and absorbancy of textiles Textile fibers are treated with enzymes in the absence of surfactants, with the effect of increasing the wettability and absorbency of the fibers. The enzymes are pectinases, cellulases, proteases, lipases or combinations thereof. The wetting properties o... | 08/20/2002 |
| 6432689 | Alkaliphilic and thermophilic microorganisms and enzymes obtained therefrom The present invention provides thermophilic alkaliphilic bacteria designated Thermopallium natronophilum and thermophilic alkaliphilic polypeptides obtainable therefrom. It also provides compositions, particularly detergent compositions comprising the pol... | 08/13/2002 |
| 6426211 | Xylanase derived from a Bacillus species, expression vectors for such xylanase and other proteins, host organisms therefor and use thereof A purified xylanase derived from B. Pumilus PRL B12 is disclosed. This xylanase is efficient for use in the biobleaching of wood pulp, permitting a strong reduction in the quantity of chlorine used and AOX compounds produced in classical and ECF wood pulp... | 07/30/2002 |
| 6426410 | Phenol oxidizing enzymes Disclosed herein are novel phenol oxidizing enzymes naturally-produced by strains of the species Stachybotrys which possess a pH optima in the alkaline range and which are useful in modifying the color associated with dyes and colored compounds, as well a... | 07/30/2002 |
| 6423523 | Xylanase derived from a bacillus species, expression vectors for such xylanase and other proteins, host organisms therefor and use thereof A purified xylanase derived from B. Pumilus PRL B12 is disclosed. This xylanase is efficient for use in the biobleaching of wood pulp, permitting a strong reduction in the quantity of chlorine used and AOX compounds produced in classical and ECF wood pulp... | 07/23/2002 |
| 6420147 | Haloalkaliphilic microorganisms Haloalkaliphilic bacteria have been isolated from samples of soil, water, sediment, trona (NaHCO3.Na.sub.2 CO3.2H.sub.2 O) and a number of other sources obtained from in and around hypersaline soda lakes. These bacteria have been ana... | 07/16/2002 |
| 6413749 | Granule containing protein and corn starch layered on an inert particle Granules are prepared containing an admixture of protein and starch layered over an inert particle. Proteins include pharmaceutically important proteins such as hormones, or industrially important proteins such as enzymes including proteases, amylases, li... | 07/02/2002 |
| 6399329 | Phenol oxidizing enzymes The invention relates to phenol oxidizing enzymes encoded by nucleic acids capable of hybridizing to the nucleic acid having the sequence shown in SEQ ID NO: 1 and in particular phenol oxidizing enzymes obtainable from fungus. Particularly provided are nu... | 06/04/2002 |
| 6395532 | Modified enzymes and their use for peptide synthesis The present invention relates to modified enzymes with one or more amino acid residues from an enzyme being replaced by cysteine residues, where at least some of the cysteine residues are modified by replacing thiol hydrogen in the cysteine residue with a... | 05/28/2002 |
| 6368833 | Esterases, DNA encoding therefor and vectors and host incorporating same A novel DNA is provided which encodes an enzyme having esterolytic activity isolated from Aspergillus. Also provided for is a method of isolating DNA encoding an enzyme having esterolytic activity from organisms which possess such DNA, transformation of t... | 04/09/2002 |
| 6358715 | Production of ascorbic acid The present invention provides for the production of ASA from yeast capable of producing ASA from KLG. The present invention provides methods for the production of ASA as well as recombinant yeast capable of producing ASA from a carbon source.... | 03/19/2002 |
| 6346407 | Xylanase, microorganisms producing it, DNA molecules, methods for preparing this xylanase and uses of the latter The invention relates to a xylanase originating from a Bacillus strain and particularly to Bacillus sp. strain 720/1 (LMG P-14798) and to xylanase obtained from derivatives and mutants of this strain. The xylanase of the invention is active over a wide ra... | 02/12/2002 |
| 6329332 | Pleurotus phenol oxidizing enzymes The present invention provides novel phenol oxidizing enzymes naturally-produced by strains of the species Pleurotus ostreatus which possess a pH optima in the alkaline range and which are useful in modifying the color associated with dyes and colored com... | 12/11/2001 |
| 6316241 | Alpha/beta hydrolase-fold enzymes The present invention relates to the identification of novel hydrolases in gram positive microorganisms. The present invention provides amino acid sequences for the hydrolase. The present invention provides host cells which comprise nucleic acid encoding ... | 11/13/2001 |
| 6312936 | Multiply-substituted protease variants Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occ... | 11/06/2001 |
| 6303354 | Microbial production of indigo There is provided an improved process for the biosynthetic production of indigo, the improvement comprising removing unwanted by-products such as isatin or indirubin from the broth in which such indigo is produced. Isatin can be removed by enzymatic activ... | 10/16/2001 |
| 6287841 | High alkaline serine protease New PB92 or Subtilisin 309 mutant serine proteases are provided having specific mutations, resulting in an surprisingly better wash performance or in an improved storage stability with at similar or even better wash performance. These PB92 or Subtilisin 3... | 09/11/2001 |
| 6284512 | Chemically modified mutant enzymes and methods for producing them, and screening them for amidase and/or esterase activity The present invention relates to a method for screening chemically modified mutant enzymes for amidase and/or esterase activity. This method includes providing a chemically modified mutant enzyme with one or more amino acid residues from an enzyme being r... | 09/04/2001 |
| 6277617 | Chemically modified enzymes Modified enzymes are provided in which at least one amino acid, such as asparagine, leucine, methionine or serine, of an enzyme is replaced with a cysteine and the thiol hydrogen is replaced with a substituent group providing a thiol side chain selected f... | 08/21/2001 |
| 6271012 | Protease muteins and their use in detergents New proteolytic enzymes are provided exhibiting improved properties for application in detergents, especially laundry detergents. These enzymes are obtained by expression of a gene encoding a proteolytic enzyme having an amino acid sequence which differs ... | 08/07/2001 |
| 6268196 | Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions Improved methods of treating cellulose containing fabrics with cellulase comprising contacting the cellulose fabrics with truncated cellulase enzyme. Treatment of cellulose containing fabrics with cellulase core domains of the invention are disclosed as o... | 07/31/2001 |
| 6265204 | DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi The invention includes novel fusion nucleic acids encoding fusion polypeptides which when expressed in a filamentous fungus result in the expression of fusion polypeptides. The fusion nucleic acids comprise four nucleic acids which encode a fusion polypep... | 07/24/2001 |
| 6261829 | Process for combating microorganisms The invention relates to a process of combatting micro-organisms in industrial processes, particularly in the wood processing industry, by adding glucose oxidase and optionally glucose or a source of glucose to the process solution or slurry.... | 07/17/2001 |
| 6258563 | Increasing production of proteins in gram-positive microorganisms The present invention relates to secretion in Gram-positive microorganisms. The present invention provides the nucleic acid amino acid sequences for the Bacillus subtilis secretion factors SecDF. The present invention also provides improved methods for th... | 07/10/2001 |
| 6254645 | Enzymatic modification of the surface of a polyester fiber or article A method is provided for improving the uptake of a cationic compound onto a polyester article starting material, comprising the steps of: (a) obtaining a polyesterase enzyme; (b) contacting said polyesterase enzyme with said polyester article starting mat... | 07/03/2001 |
| 6251144 | Enzymatic compositions and methods for producing stonewashed look on indigo-dyed denim fabric and garments During the desizing and enzymatic stonewashing of denim fabric and/or garments, redeposition of blue color often occurs back onto the surfaces of the denim. The invention relates to a redepositing or backstain inhibiting composition and a method requiring... | 06/26/2001 |
| 6248541 | Screening under nutrient limited conditions Described herein are methods for obtaining from an initial population of cells a plurality of subpopulations of cells having a similar density by growing samples from the initial population in medium having a limiting nutrient. Also provided are methods f... | 06/19/2001 |
| 6238895 | Production of aspartic and malic acids with microbacterium The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as methods for such use and the conversion solution produced... | 05/29/2001 |
| 6218164 | Thermopallium bacteria and enzymes obtainable therefrom The present invention provides thermophilic alkaliphilic bacteria designated Thermopallium natronophilum and thermophilic alkaliphilic polypeptides obtainable therefrom. It also provides compositions, particularly detergent compositions comprising the pol... | 04/17/2001 |
| 6217942 | Lignin based coating A method is provided for producing a coated article comprising: (a) preparing a solution of lignin; (b) mixing the lignin solution with a phenol oxidizing enzyme; (c) incubating the mixture from said step (b) under conditions and for a time sufficient to ... | 04/17/2001 |