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Assignee: Genencor International, Inc.


Location: Rochester, NY
No. of patents: 130

1        
NumberTitleIssue Date
7300779Preparation of a granule containing protein, corn starch and sugar layered on an inert particle
Granules that include a protein core are described. The protein core includes a protein matrix which includes a protein mixed together with a starch. The protein matrix can be layered over a seed particle or the protein core can be homogeneous. The protein can be an...
11/27/2007
6673590Multiply-substituted protease variants with altered net charge for use in detergents
Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occ...
01/06/2004
6642031Microorganisms with ability to degrade indole and enzymes therefrom
There is provided novel indole oxidase activity isolated from P. putida, such indole oxidase activity is believed to be useful in the biosynthetic production of indigo from its precursor indole. Also provided are compositions of matter comprising the indo...
11/04/2003
6599722Method for producing ascorbic acid intermediates
The present invention relates to non-fermentative methods for the production of ASA intermediates, KDG, DKG and KLG and methods for the regeneration of co-factor. The invention provides genetically engineered host cells comprising heterologous nucleic aci...
07/29/2003
6586221Subtilisin variants multiply-substituted subtilising variants having a substitution at position 76
Novel carbonyl hydrolase variants derived from the DNA sequences of naturally-occurring or recombinant non-human carbonyl hydrolases are disclosed. The variant carbonyl hydrolases, in general, are obtained by in vitro modification of a precursor DNA seque...
07/01/2003
6558933Mutant 1,3-propanediol dehydrogenase
The present invention relates to mutant 1,3-propanediol dehydrogenase and a novel microorganism that is capable of growing in concentrations of at least 105 g/l 1,3-propanediol, levels normally toxic to wild-type microorganisms. The present invention also...
05/06/2003
6528255Proteases from gram positive organisms
The present invention relates to the identification of metalloproteases in gram positive microorganisms and provides the nucleic acid and amino acid sequences for a metalloprotease. Host cells having a mutation or deletion of part or all of the gene encod...
03/04/2003
6489108Proteases from gram positive organisms
The present invention relates to the identification of novel metalloproteases in gram positive microorganisms. The present invention provides the nucleic acid and amino acid sequences for the metalloprotease. The present invention also provides host cells...
12/03/2002
6482628Multiply-substituted protease variants
Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occ...
11/19/2002
6468773Mutant 1,3-propandiol dehydrogenase
The present invention relates to mutant 1,3-propanediol dehydrogenase and a novel microorganism that is capable of growing in concentrations of at least 105 g/l 1,3-propanediol, levels normally toxic to wild-type microorganisms. The present invention also...
10/22/2002
6436696Enzyme treatment to enhance wettability and absorbancy of textiles
Textile fibers are treated with enzymes in the absence of surfactants, with the effect of increasing the wettability and absorbency of the fibers. The enzymes are pectinases, cellulases, proteases, lipases or combinations thereof. The wetting properties o...
08/20/2002
6432689Alkaliphilic and thermophilic microorganisms and enzymes obtained therefrom
The present invention provides thermophilic alkaliphilic bacteria designated Thermopallium natronophilum and thermophilic alkaliphilic polypeptides obtainable therefrom. It also provides compositions, particularly detergent compositions comprising the pol...
08/13/2002
6426211Xylanase derived from a Bacillus species, expression vectors for such xylanase and other proteins, host organisms therefor and use thereof
A purified xylanase derived from B. Pumilus PRL B12 is disclosed. This xylanase is efficient for use in the biobleaching of wood pulp, permitting a strong reduction in the quantity of chlorine used and AOX compounds produced in classical and ECF wood pulp...
07/30/2002
6426410Phenol oxidizing enzymes
Disclosed herein are novel phenol oxidizing enzymes naturally-produced by strains of the species Stachybotrys which possess a pH optima in the alkaline range and which are useful in modifying the color associated with dyes and colored compounds, as well a...
07/30/2002
6423523Xylanase derived from a bacillus species, expression vectors for such xylanase and other proteins, host organisms therefor and use thereof
A purified xylanase derived from B. Pumilus PRL B12 is disclosed. This xylanase is efficient for use in the biobleaching of wood pulp, permitting a strong reduction in the quantity of chlorine used and AOX compounds produced in classical and ECF wood pulp...
07/23/2002
6420147Haloalkaliphilic microorganisms
Haloalkaliphilic bacteria have been isolated from samples of soil, water, sediment, trona (NaHCO3.Na.sub.2 CO3.2H.sub.2 O) and a number of other sources obtained from in and around hypersaline soda lakes. These bacteria have been ana...
07/16/2002
6413749Granule containing protein and corn starch layered on an inert particle
Granules are prepared containing an admixture of protein and starch layered over an inert particle. Proteins include pharmaceutically important proteins such as hormones, or industrially important proteins such as enzymes including proteases, amylases, li...
07/02/2002
6399329Phenol oxidizing enzymes
The invention relates to phenol oxidizing enzymes encoded by nucleic acids capable of hybridizing to the nucleic acid having the sequence shown in SEQ ID NO: 1 and in particular phenol oxidizing enzymes obtainable from fungus. Particularly provided are nu...
06/04/2002
6395532Modified enzymes and their use for peptide synthesis
The present invention relates to modified enzymes with one or more amino acid residues from an enzyme being replaced by cysteine residues, where at least some of the cysteine residues are modified by replacing thiol hydrogen in the cysteine residue with a...
05/28/2002
6368833Esterases, DNA encoding therefor and vectors and host incorporating same
A novel DNA is provided which encodes an enzyme having esterolytic activity isolated from Aspergillus. Also provided for is a method of isolating DNA encoding an enzyme having esterolytic activity from organisms which possess such DNA, transformation of t...
04/09/2002
6358715Production of ascorbic acid
The present invention provides for the production of ASA from yeast capable of producing ASA from KLG. The present invention provides methods for the production of ASA as well as recombinant yeast capable of producing ASA from a carbon source....
03/19/2002
6346407Xylanase, microorganisms producing it, DNA molecules, methods for preparing this xylanase and uses of the latter
The invention relates to a xylanase originating from a Bacillus strain and particularly to Bacillus sp. strain 720/1 (LMG P-14798) and to xylanase obtained from derivatives and mutants of this strain. The xylanase of the invention is active over a wide ra...
02/12/2002
6329332Pleurotus phenol oxidizing enzymes
The present invention provides novel phenol oxidizing enzymes naturally-produced by strains of the species Pleurotus ostreatus which possess a pH optima in the alkaline range and which are useful in modifying the color associated with dyes and colored com...
12/11/2001
6316241Alpha/beta hydrolase-fold enzymes
The present invention relates to the identification of novel hydrolases in gram positive microorganisms. The present invention provides amino acid sequences for the hydrolase. The present invention provides host cells which comprise nucleic acid encoding ...
11/13/2001
6312936Multiply-substituted protease variants
Novel protease variants derived from the DNA sequences of naturally-occurring or recombinant non-human proteases are disclosed. The variant proteases, in general, are obtained by in vitro modification of a precursor DNA sequence encoding the naturally-occ...
11/06/2001
6303354Microbial production of indigo
There is provided an improved process for the biosynthetic production of indigo, the improvement comprising removing unwanted by-products such as isatin or indirubin from the broth in which such indigo is produced. Isatin can be removed by enzymatic activ...
10/16/2001
6287841High alkaline serine protease
New PB92 or Subtilisin 309 mutant serine proteases are provided having specific mutations, resulting in an surprisingly better wash performance or in an improved storage stability with at similar or even better wash performance. These PB92 or Subtilisin 3...
09/11/2001
6284512Chemically modified mutant enzymes and methods for producing them, and screening them for amidase and/or esterase activity
The present invention relates to a method for screening chemically modified mutant enzymes for amidase and/or esterase activity. This method includes providing a chemically modified mutant enzyme with one or more amino acid residues from an enzyme being r...
09/04/2001
6277617Chemically modified enzymes
Modified enzymes are provided in which at least one amino acid, such as asparagine, leucine, methionine or serine, of an enzyme is replaced with a cysteine and the thiol hydrogen is replaced with a substituent group providing a thiol side chain selected f...
08/21/2001
6271012Protease muteins and their use in detergents
New proteolytic enzymes are provided exhibiting improved properties for application in detergents, especially laundry detergents. These enzymes are obtained by expression of a gene encoding a proteolytic enzyme having an amino acid sequence which differs ...
08/07/2001
6268196Method and compositions for treating cellulose containing fabrics using truncated cellulase enzyme compositions
Improved methods of treating cellulose containing fabrics with cellulase comprising contacting the cellulose fabrics with truncated cellulase enzyme. Treatment of cellulose containing fabrics with cellulase core domains of the invention are disclosed as o...
07/31/2001
6265204DNA sequences, vectors, and fusion polypeptides for secretion of polypeptides in filamentous fungi
The invention includes novel fusion nucleic acids encoding fusion polypeptides which when expressed in a filamentous fungus result in the expression of fusion polypeptides. The fusion nucleic acids comprise four nucleic acids which encode a fusion polypep...
07/24/2001
6261829Process for combating microorganisms
The invention relates to a process of combatting micro-organisms in industrial processes, particularly in the wood processing industry, by adding glucose oxidase and optionally glucose or a source of glucose to the process solution or slurry....
07/17/2001
6258563Increasing production of proteins in gram-positive microorganisms
The present invention relates to secretion in Gram-positive microorganisms. The present invention provides the nucleic acid amino acid sequences for the Bacillus subtilis secretion factors SecDF. The present invention also provides improved methods for th...
07/10/2001
6254645Enzymatic modification of the surface of a polyester fiber or article
A method is provided for improving the uptake of a cationic compound onto a polyester article starting material, comprising the steps of: (a) obtaining a polyesterase enzyme; (b) contacting said polyesterase enzyme with said polyester article starting mat...
07/03/2001
6251144Enzymatic compositions and methods for producing stonewashed look on indigo-dyed denim fabric and garments
During the desizing and enzymatic stonewashing of denim fabric and/or garments, redeposition of blue color often occurs back onto the surfaces of the denim. The invention relates to a redepositing or backstain inhibiting composition and a method requiring...
06/26/2001
6248541Screening under nutrient limited conditions
Described herein are methods for obtaining from an initial population of cells a plurality of subpopulations of cells having a similar density by growing samples from the initial population in medium having a limiting nutrient. Also provided are methods f...
06/19/2001
6238895Production of aspartic and malic acids with microbacterium
The use of strains of the genus Microbacterium for the production of organic acids or amino acids by the enzymatic conversion of a fumaric acid to the organic acid or amino acid desired, as well as methods for such use and the conversion solution produced...
05/29/2001
6218164Thermopallium bacteria and enzymes obtainable therefrom
The present invention provides thermophilic alkaliphilic bacteria designated Thermopallium natronophilum and thermophilic alkaliphilic polypeptides obtainable therefrom. It also provides compositions, particularly detergent compositions comprising the pol...
04/17/2001
6217942Lignin based coating
A method is provided for producing a coated article comprising: (a) preparing a solution of lignin; (b) mixing the lignin solution with a phenol oxidizing enzyme; (c) incubating the mixture from said step (b) under conditions and for a time sufficient to ...
04/17/2001
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