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Assignee: Gambro, Inc.


Location: Lakewood, CO
No. of patents: 58

1    
NumberTitleIssue Date
7279107Blood component processing system, apparatus, and method
A system and method are used in connection with processing of blood components. The processing of blood components may involve centrifugal separation and/or filtering of the blood components. In some examples, at least some blood components are centrifugally separat...
10/09/2007
7220747Method for preventing damage to or rejuvenating a cellular blood component using mitochondrial enhancer
This invention provides methods for treating cellular blood components and other cells containing mitochondria to improve vital qualities of the cells by contacting the cells with a mitochondrial enhancer to the cells. Mitochondrial enhancers prevent damage to and r...
05/22/2007
7186543Preparation of vaccines using a photosensitizer and light
Methods are provided for treating a vaccine containing infectious particles which may be viral, bacterial, and/or cellular in nature. Preferred methods include the steps of adding an effective, non-toxic amount of an endogenous photosensitizer to the fluid and expos...
03/06/2007
7183045Removal of adenine during a pathogen reduction process in whole blood or red blood cell by dilution
The methods of this invention involve preventing the formation of a complex between adenine and riboflavin by reducing the amount of adenine in a solution containing blood or blood components to be pathogen reduced. ...
02/27/2007
7169352Extracorporeal blood processing methods and apparatus
This invention provides a method for controlling a fluid separation system, preferably a blood apheresis system having a leukocyte reduction chamber. The method utilizes a three-level alarm system. A first-level alarm condition is triggered in response to a pressure...
01/30/2007
7166217Methods and apparatuses for blood component separation
A system for separating a composite fluid into component parts thereof, including: a centrifuge having a rotor with a separation space and at least two valve members disposed thereon and a container set having a separation container adapted to be disposed in the sep...
01/23/2007
7108672Extracorporeal blood processing methods and apparatus
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the oper...
09/19/2006
7097774Method for processing a blood product with a bag set having a multi-way connector
The claimed invention refers to a centrifuge intended for processing blood and blood components and with its function based on the effective utilisation of ring type blood processing bags with associated secondary bags and other accessories. The most outstanding fea...
08/29/2006
7094378Method and apparatus for inactivation of biological contaminants using photosensitizers
Methods and apparatuses for treating fluids to inactivate microorganisms which may be present therein, said fluid containing one or more components selected from the group consisting of protein, blood and blood constituents are provided. The methods comprise adjusti...
08/22/2006
7094197Method for fluid separation devices using a fluid pressure balanced configuration
A method for separating a composite fluid into components in a centrifugal fluid separation system. The system includes a rotor that has a composite fluid containment area, an inlet channel, a peripheral separation channel, outlet channels and separated component co...
08/22/2006
7077559Container or bag mixing apparatuses and/or methods
A mixing system, apparatus and/or method. Pathogen reduction of and/or mixing storage solutions into blood or blood components are useful purposes for these. Squeezing or clapping devices may be used to activate the mixing process, as may rotational devices or later...
07/18/2006
7072769Extracorporeal blood processing information management system
A blood component collection system with manipulation and optimization capabilities. In one embodiment, process parameters are derived from an input/configured predetermined blood component yield and which is based upon the maximization of at least one process param...
07/04/2006
7052606Methods and apparatus for leukoreduction of red blood cells
A method and apparatus for red blood collection and filtration is provided wherein a red blood cell collection assembly provides for leukoreduction filtration concurrent with or soon after the red blood cell separation and collection procedure. Such procedures invol...
05/30/2006
7049110Inactivation of West Nile virus and malaria using photosensitizers
Methods and apparatuses are provided for inactivation of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an effective, non-toxic a...
05/23/2006
7029430Centrifugal separation apparatus and method for separating fluid components
An apparatus and method are provided for separating components of a fluid or particles. A separation vessel having a barrier dam is provided to initially separate an intermediate density components of a fluid, and a fluid chamber is provided to further separate thes...
04/18/2006
6994790Whole blood collection and processing method
A method is disclosed for collecting and processing whole blood. Whole blood is collected at several remote donor sites and transported to a central blood-processing center, where information regarding demand for blood products is used to direct processing of whole ...
02/07/2006
6949214Method and apparatus for injection molding a fluid filter
A filter having a substantially cylindrical or slightly tapered body design which has a plurality of elongated apertures formed therethrough. Each aperture is defined side to side by a pair of elongated, wedge-like rib members disposed one on each side of each apert...
09/27/2005
6945948Extra-corporeal dual stage blood processing method and apparatus
Methods and apparatus particularly involving the separation of blood into blood components and the collection of such components are disclosed. In one aspect, an extra-corporeal method for the collection of plasma and red blood cells is provided, wherein the collect...
09/20/2005
6912917Differential fluid parameter determination
Methods and apparatuses for determining a fluid parameter in a vessel by altering a property of the fluid, sensing the difference in the property after the fluid is altered, particularly as related to the property in an unaltered portion of the fluid. ...
07/05/2005
6869411Apparatus for producing blood component products
A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two on-line yield determination techniques are utilized to determine the yiel...
03/22/2005
6861033Purified water supply system for high demand devices and applications
A water supply sub-system for connection to a main water supply system includes a storage tank having an inlet with a flow control valve for connection to the main water supply system. The sub-system may be disconnected from the main system and configured as a close...
03/01/2005
6855102Method for separating cells, especially platelets, and bag assembly therefor
Method of separating cells in a centrifuge, preferably for producing platelets. A cell suspension is provided in a processing bag and is centrifuged. The cell enriched fraction is transferred to a storage bag via an outlet tube. The outlet tube is arranged with a po...
02/15/2005
6843961Reduction of contaminants in blood and blood products using photosensitizers and peak wavelengths of light
Methods and apparatuses are provided for inactivation of pathogens in fluids containing blood products. Preferred methods include the steps of adding an effective, nontoxic amount of a photosensitizer such as riboflavin to the blood product and exposing the fluid to...
01/18/2005
6835171Centrifuge and container system for treatment of blood and blood components
A centrifuge is provided for the separation and/or treatment of cells in a substantially annular or partially annular separation bag connected by at least one tube to at least one secondary bag. The centrifuge comprises a rotor bowl connected at the upper end of a r...
12/28/2004
6828323Isoalloxazine derivatives to neutralize biological contaminants
Methods are provided for neutralization of microorganisms in fluids or on surfaces. Preferably the fluids contain blood or blood products and comprise biologically active proteins. Preferred methods include the steps of adding an activation-effective amount of a mic...
12/07/2004
6790195Extracorporeal blood processing methods and apparatus
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the oper...
09/14/2004
6773389Fluid separation devices, systems and/or methods using a fluid pressure driven and/or balanced configuration
A centrifugal fluid separation system separates a composite fluid into components. The system includes a rotor that has a composite fluid containment area, an inlet channel, a peripheral separation channel, outlet channels and separated component collection areas, w...
08/10/2004
6740239Method and apparatus for processing blood and blood components
The claimed invention relates to a method and a device for processing blood concentrate products before they are exposed to a continued process for extracting those remaining medicinally interesting sub-components. The appropriate pre-processing, in relation to the ...
05/25/2004
6736768Fluid separation devices, systems and/or methods using a fluid pressure driven and/or balanced approach
A centrifugal separation device separates a composite fluid, such as blood, into the components thereof. The fluid is delivered to a fluid receiving area in a rotor from which area the fluid travels through a radial inlet channel having an inlet channel height to a ...
05/18/2004
6726671Cell storage maintenance and monitoring system
A cell storage maintenance and monitoring system includes a blood product storage container, such as a flexible bag, and a microporous membrane which may be attached to an inner wall of the blood storage container to form a contained space between the inner wall and...
04/27/2004
6689042Centrifuge and container system for treatment of blood and blood components
A centrifuge with an associated container system in the form of cassettes for separation and treatment of blood or blood components has been developed. The centrifuge includes a rotor having a central compartment in the form of a tubular shaft cavity exte...
02/10/2004
6656105Centrifuge for processing blood and blood components in ring-type blood processing bags
A centrifuge intended for processing blood and blood components of use with a ring type blood processing bag with associated secondary bags. The rotor of the centrifuge has supports arranged along its periphery and a rotating inner lid a clamp function th...
12/02/2003
6652476Method and apparatus for producing blood component products
A method and apparatus for producing blood component products. In one embodiment, a plurality of a predetermined type of blood component is harvested from a source of whole blood. At least two on-line yield determination techniques are utilized to determi...
11/25/2003
6613009Extracorporeal blood processing methods and apparatus
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which direc...
09/02/2003
6614212Differential conductivity hemodynamic monitor
Method and apparatus for quantitatively determining a degree of recirculalion flow in a vessel of a fluid by altering the electrical conductivity of the fluid, sensing the difference in electromagnetic field after the fluid is altered, and integrating the...
09/02/2003
6548241Storage solution containing photosensitizer for inactivation of biological contaminants
A platelet/additive solution comprising bicarbonate, citrate and glucose. Additionally, a platelet/additive and treatment solution comprising bicarbonate, citrate, glucose and a photosensitizer....
04/15/2003
6526357Associated parameter measuring and/or monitoring such as in the evaluation of pressure differences
Correction quantities are generated for yielding closer approximations of actual parameters. These are obtained by preliminarily subjecting parametric transducers to pre-selected parametric values and recording the measured values for each transducer in a...
02/25/2003
6514189Centrifugal separation method for separating fluid components
An apparatus and method are provided for separating components of a fluid or particles. A separation vessel having a barrier dam is provided to initially separate an intermediate density components of a fluid, and a fluid chamber is provided to further se...
02/04/2003
6497674Extracorporeal blood processing methods and apparatus
An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which direc...
12/24/2002
6468427Fluid filter for use in extracorporeal blood processing
A filter having a substantially cylindrical or slightly tapered body design which has a plurality of elongated apertures formed therethrough. Each aperture is defined side to side by a pair of elongated, wedge-like rib members disposed one on each side of...
10/22/2002
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