...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.
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| Number | Title | Issue Date |
| 8138306 | Separation method The present invention relates to a method of separating a compound from a liquid, which method comprises providing a separation matrix comprising at least one uncharged ligand; providing a liquid wherein the compound to be separated is present in a positively charge... | 03/20/2012 |
| 8137563 | Preparation of polysaccharide beads The present invention relates a method of preparing agarose beads, which method results in a population of beads which are of relatively uniform particle size. In an advantageous embodiment, the beads are of a particle size less than 10 μm, and the coefficient of v... | 03/20/2012 |
| 8137559 | Liquid clarification The present invention relates to liquid clarification. More closely, the invention relates to beverage clarification, such as reduction of colloidal (not microbial) haze-causing substances in beer or related beverages such as wine, juices, flavorings etc. The method... | 03/20/2012 |
| 8137549 | Automated packing system and method for chromatography columns A column packing system comprises a control unit provided with software for calculating the breakpoint where a movable adapter comes into contact with a settled bed of bed media. The calculated breakpoint is used by the control unit to determine how much further the... | 03/20/2012 |
| 8133395 | Automated column packing method A method for automatically without any required manual interaction packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps a)-f) which all are performed automatically: a) fill... | 03/13/2012 |
| 8117901 | Determination of slurry concentration A method for determining the concentration of a chromatographic medium in a liquid slurry comprises the steps of: providing a column (1) having a top end (3) and a bottom end (2) and adapted to retain a chromatographic medium therein; introducin... | 02/21/2012 |
| 8114280 | Separation matrix and method of purification The present invention relates to a separation matrix comprised of a porous support to which ligands have been immobilized, wherein said ligands comprise at least one sulphonamide and the R group of the sulphonyl comprises an aromatic group. The nitrogen of the sulph... | 02/14/2012 |
| 8093373 | Plasmid purification The present invention relates to a method of isolating at least one plasmid from other components of a liquid, which method comprises the steps of providing a separation matrix comprised of one or more porous carriers, which carrier(s) present anion exchange groups ... | 01/10/2012 |
| 8093005 | Preparation and use of a reactive solid support surface A method of preparing a protein-resistant reactive solid support surface is disclosed. The method comprises the steps of providing a solid support having a hydrogel coating with a plurality of binding elements, coupling a protein resistant compound to the hydrogel v... | 01/10/2012 |
| 8092683 | Multi-modal ion exchange chromatography resins The present invention relates to a method of preparing a library of resins which are useful in chromatography, which method comprises creating a diversity of multi-modal ion exchange resins; and providing the diversity in a parallel system in which each resin is pre... | 01/10/2012 |
| 8092682 | Matrix for separation of polyethers and method of separation The present invention relates to a separation matrix comprised of a support to the surfaces of which polymer chains have been coupled, wherein each polymer chain presents recurring proton-donating groups and at least the surface of the support is substantially hydro... | 01/10/2012 |
| 8092073 | Separation media slurry tank A tank adapted to be used for suspending separation media slurry before transferring the separation media slurry to a column or a container comprises: an impeller (7) adapted to rotate in order to mix the media slurry, ... | 01/10/2012 |
| 8070958 | Separation matrix having a ligand density gradient The present invention relates to a separation matrix comprised of ligands coupled to the surfaces of a porous support, such as one or more porous particles, wherein the ligands provide at least one chemical gradient within the support. In the most advantageous embod... | 12/06/2011 |
| 8066882 | Column packing method A method for packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps of: a) estimating a slurry concentration; b) filling the column (3) with a certain volume of the sl... | 11/29/2011 |
| 8060328 | Method and apparatus for quantitating surface-binding optical resonance profiles An apparatus for quantitation of surface-binding optical resonance profiles includes a calibration module including a calibration scan result fetcher, a calibration profile creation module, and a fitting module. The fitting module includes an experimental scan resul... | 11/15/2011 |
| 8021626 | Method and device for laminar flow on a sensing surface Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods... | 09/20/2011 |
| 7993899 | Method for the purification of chymosin We describe a method for purifying chymosin comprising providing an aqueous liquid sample containing chymosin and a separation medium comprising a base matrix and a plurality of firmly attached ligands that are capable of binding to chymosin, contacting the matrix w... | 08/09/2011 |
| 7989215 | Methods and systems for adding a reagent to an analyte in a gel The present invention relates to methods and systems for adding a reagent to an analyte in a gel. The invention further provides methods and systems for transferring liquid analyte reagent mixtures from a gel to a second vessel, such as a microtitre plate. The inven... | 08/02/2011 |
| 7988858 | Method for generating metal chelating affinity ligands The present invention relates to a method for generating at least one polydentate metal chelating affinity ligand, which method comprises the steps of (a) providing at least one scaffold defined by the general formula (I): H2N—(X1 | 08/02/2011 |
| 7966227 | System for configuring a chemical separation system The present invention relates to a configuration system for configuring and ordering a chemical separation system, which configuration system comprises a configuration tool, a database comprising data relating to chemical separation hardware modules and the linkage ... | 06/21/2011 |
| 7964075 | Electrodic bridge The present invention relates to an electrode bridge or sample application bridge for use in electrophoresis, preferably isoelectric focusing, IEF. More closely, the invention relates to an electrodic bridge or sample loading bridge for preventing denaturant depleti... | 06/21/2011 |
| D639980 | Chromatography column | 06/14/2011 |
| D639979 | Tie-bar for a chromatography column | 06/14/2011 |
| 7943029 | Method, composition and kit for isoelectric focusing The present invention relates to a method, composition and a kit for isoelectric focusing. More closely, the present invention involves the use of to modified carrier ampholytes which are easy to separate from the proteins/peptides following finished focusing. The m... | 05/17/2011 |
| 7925448 | Method and system for determination of molecular interaction parameters A method of determining kinetic parameters for a reversible molecular interaction between a ligand immobilized to a solid support surface and a binding partner to the ligand in solution, comprises sequentially, without intermediate regeneration or renewal of the imm... | 04/12/2011 |
| 7901581 | Chromatography method The present invention relates to a simulated moving bed process, wherein at least one adsorbent is washed after binding of target compound and wherein the outlet of wash liquid from the adsorbent is subsequently passed onto another adsorbent for binding of target co... | 03/08/2011 |
| 7897257 | Magnetic beads comprising an outer coating of hydrophilic porous polymer and method of making thereof The present invention relates to magnetic beads suitable for, for example, isolation of proteins, cells, and viruses and also for diagnostic applications and cell cultivation. The magnetic beads are composite beads with an inner core of metal particles, which are co... | 03/01/2011 |
| 7896310 | Pinch valve A pinch valve is adapted to hold at least one flexible tube in a tube holding room (7) and comprises a plunger (13) adapted to protrude into the tube holding room and pinch the tube against an opposite side wall (11) thereof. The plunger (13 | 03/01/2011 |
| 7881517 | Method of analysing cell samples, by creating and analysing a resultant image A method is provided for comparing multiple samples of cell extract containing a plurality of components. The method comprises the steps of preparing at least two samples of cell extract from at least two groups of cells and of exposing each of said sample of said c... | 02/01/2011 |
| 7879244 | Method for anion-exchange adsorption and thioether anion-exchangers A method for the removal of a substance, which has a negative charge and which is present in an aqueous liquid (I). The method comprises the steps of: (i) contacting the liquid with an anion-exchanger (1) that comprises mixed mode anion-exchanging ligands in which t... | 02/01/2011 |
| 7834158 | Mutated immunoglobulin-binding protein The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13... | 11/16/2010 |
| 7824924 | Analytical measuring and evaluation method for molecular interactions The invention relates to an analytical measuring and evaluation method for determining the interaction parameters between an analyte and a ligand, preferably in a biosensor. According to the inventive method, the concentration of the analyte is gradually changed at ... | 11/02/2010 |
| 7822568 | Method and apparatus for quantitating surface-binding optical resonance profiles Empirical profile curve fits (260) are used to quantitative the surface optical resonance profiles (268) using two EPF stages of calibration and fit. The calibration surface binding optical resonance scan is obtained with fine angle or wavelength spaci... | 10/26/2010 |
| 7820042 | Method for removing air from a chromatography column The invention relates to a method for removing air from the bed space of a chromatography column. The method involves use a chromatography column having an inner wall which comprises at least one elongated groove through which air can pass from the bed space to a ch... | 10/26/2010 |
| 7819953 | Air trap The invention relates to air traps 13, particularly for chromatography systems, chromatography systems using such air traps and methods of using such chromatography systems, in which the air trap comprises a liquid inlet pipe 33, a liquid outlet pipe | 10/26/2010 |
| 7811515 | Method and device for laminar flow on a sensing surface Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods... | 10/12/2010 |
| 7811435 | Method for scanning gels and gel folder for use in the method The present invention relates to a method of scanning an electrophoretic gel after electrophoresis of fluorescence labelled samples, comprising inserting the gel into a separate low fluorescent scanning unit, in the shape of a gel folder or a frame, and scanning the... | 10/12/2010 |
| 7785473 | Chromatography column and method of maintenance A chromatography column and method of maintenance is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within t... | 08/31/2010 |
| 7780853 | Method for conducting maintenance on a chromatography column The present invention relates to methods for conducting maintenance on chromatography columns used in industrial-scale chromatography. In particular, the invention is concerned with safer methods for performing maintenance on such columns, such as cleaning and repla... | 08/24/2010 |
| 7750129 | Process for the purification of antibodies The present invention relates to a process for the purification of antibodies from one or more impurities in a liquid, which process comprises contacting said liquid with a first chromatography resin comprised of a support to which multi-modal ligands have been immo... | 07/06/2010 |