U.S. patents available from 1976 to present.
U.S. patent applications available from 2005 to present.

Icon_funbox Did You Know...

...that in the early 1940s GE engineer James Wright was charged with a task of utmost importance to the war effort: develop a cheap substitute for rubber that could be used to produce tires, gas masks and a whole host of military gear. Wright tackled the task diligently -- and wound up inventing Silly Putty.

Newsletter  PatentStorm News

Make the Most of Our Site

See this month's Top Inventors and Most Cited Patents.

Stay on top of the latest innovations by subscribing to an RSS feed.

Registered users: Manage your profile.

 

Assignee: GE Healthcare Bio-Sciences AB


Location: Uppsala, SE
No. of patents: 122

1        
NumberTitleIssue Date
8138306Separation method
The present invention relates to a method of separating a compound from a liquid, which method comprises providing a separation matrix comprising at least one uncharged ligand; providing a liquid wherein the compound to be separated is present in a positively charge...
03/20/2012
8137563Preparation of polysaccharide beads
The present invention relates a method of preparing agarose beads, which method results in a population of beads which are of relatively uniform particle size. In an advantageous embodiment, the beads are of a particle size less than 10 μm, and the coefficient of v...
03/20/2012
8137559Liquid clarification
The present invention relates to liquid clarification. More closely, the invention relates to beverage clarification, such as reduction of colloidal (not microbial) haze-causing substances in beer or related beverages such as wine, juices, flavorings etc. The method...
03/20/2012
8137549Automated packing system and method for chromatography columns
A column packing system comprises a control unit provided with software for calculating the breakpoint where a movable adapter comes into contact with a settled bed of bed media. The calculated breakpoint is used by the control unit to determine how much further the...
03/20/2012
8133395Automated column packing method
A method for automatically without any required manual interaction packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps a)-f) which all are performed automatically: a) fill...
03/13/2012
8117901Determination of slurry concentration
A method for determining the concentration of a chromatographic medium in a liquid slurry comprises the steps of: providing a column (1) having a top end (3) and a bottom end (2) and adapted to retain a chromatographic medium therein; introducin...
02/21/2012
8114280Separation matrix and method of purification
The present invention relates to a separation matrix comprised of a porous support to which ligands have been immobilized, wherein said ligands comprise at least one sulphonamide and the R group of the sulphonyl comprises an aromatic group. The nitrogen of the sulph...
02/14/2012
8093373Plasmid purification
The present invention relates to a method of isolating at least one plasmid from other components of a liquid, which method comprises the steps of providing a separation matrix comprised of one or more porous carriers, which carrier(s) present anion exchange groups ...
01/10/2012
8093005Preparation and use of a reactive solid support surface
A method of preparing a protein-resistant reactive solid support surface is disclosed. The method comprises the steps of providing a solid support having a hydrogel coating with a plurality of binding elements, coupling a protein resistant compound to the hydrogel v...
01/10/2012
8092683Multi-modal ion exchange chromatography resins
The present invention relates to a method of preparing a library of resins which are useful in chromatography, which method comprises creating a diversity of multi-modal ion exchange resins; and providing the diversity in a parallel system in which each resin is pre...
01/10/2012
8092682Matrix for separation of polyethers and method of separation
The present invention relates to a separation matrix comprised of a support to the surfaces of which polymer chains have been coupled, wherein each polymer chain presents recurring proton-donating groups and at least the surface of the support is substantially hydro...
01/10/2012
8092073Separation media slurry tank
A tank adapted to be used for suspending separation media slurry before transferring the separation media slurry to a column or a container comprises: an impeller (7) adapted to rotate in order to mix the media slurry, ...
01/10/2012
8070958Separation matrix having a ligand density gradient
The present invention relates to a separation matrix comprised of ligands coupled to the surfaces of a porous support, such as one or more porous particles, wherein the ligands provide at least one chemical gradient within the support. In the most advantageous embod...
12/06/2011
8066882Column packing method
A method for packing a media bed in a column (3) from a slurry being a dispersion of said media particles and a liquid, said method comprising the steps of: a) estimating a slurry concentration; b) filling the column (3) with a certain volume of the sl...
11/29/2011
8060328Method and apparatus for quantitating surface-binding optical resonance profiles
An apparatus for quantitation of surface-binding optical resonance profiles includes a calibration module including a calibration scan result fetcher, a calibration profile creation module, and a fitting module. The fitting module includes an experimental scan resul...
11/15/2011
8021626Method and device for laminar flow on a sensing surface
Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods...
09/20/2011
7993899Method for the purification of chymosin
We describe a method for purifying chymosin comprising providing an aqueous liquid sample containing chymosin and a separation medium comprising a base matrix and a plurality of firmly attached ligands that are capable of binding to chymosin, contacting the matrix w...
08/09/2011
7989215Methods and systems for adding a reagent to an analyte in a gel
The present invention relates to methods and systems for adding a reagent to an analyte in a gel. The invention further provides methods and systems for transferring liquid analyte reagent mixtures from a gel to a second vessel, such as a microtitre plate. The inven...
08/02/2011
7988858Method for generating metal chelating affinity ligands
The present invention relates to a method for generating at least one polydentate metal chelating affinity ligand, which method comprises the steps of (a) providing at least one scaffold defined by the general formula (I): H2N—(X1
08/02/2011
7966227System for configuring a chemical separation system
The present invention relates to a configuration system for configuring and ordering a chemical separation system, which configuration system comprises a configuration tool, a database comprising data relating to chemical separation hardware modules and the linkage ...
06/21/2011
7964075Electrodic bridge
The present invention relates to an electrode bridge or sample application bridge for use in electrophoresis, preferably isoelectric focusing, IEF. More closely, the invention relates to an electrodic bridge or sample loading bridge for preventing denaturant depleti...
06/21/2011
D639980Chromatography column
06/14/2011
D639979Tie-bar for a chromatography column
06/14/2011
7943029Method, composition and kit for isoelectric focusing
The present invention relates to a method, composition and a kit for isoelectric focusing. More closely, the present invention involves the use of to modified carrier ampholytes which are easy to separate from the proteins/peptides following finished focusing. The m...
05/17/2011
7925448Method and system for determination of molecular interaction parameters
A method of determining kinetic parameters for a reversible molecular interaction between a ligand immobilized to a solid support surface and a binding partner to the ligand in solution, comprises sequentially, without intermediate regeneration or renewal of the imm...
04/12/2011
7901581Chromatography method
The present invention relates to a simulated moving bed process, wherein at least one adsorbent is washed after binding of target compound and wherein the outlet of wash liquid from the adsorbent is subsequently passed onto another adsorbent for binding of target co...
03/08/2011
7897257Magnetic beads comprising an outer coating of hydrophilic porous polymer and method of making thereof
The present invention relates to magnetic beads suitable for, for example, isolation of proteins, cells, and viruses and also for diagnostic applications and cell cultivation. The magnetic beads are composite beads with an inner core of metal particles, which are co...
03/01/2011
7896310Pinch valve
A pinch valve is adapted to hold at least one flexible tube in a tube holding room (7) and comprises a plunger (13) adapted to protrude into the tube holding room and pinch the tube against an opposite side wall (11) thereof. The plunger (13
03/01/2011
7881517Method of analysing cell samples, by creating and analysing a resultant image
A method is provided for comparing multiple samples of cell extract containing a plurality of components. The method comprises the steps of preparing at least two samples of cell extract from at least two groups of cells and of exposing each of said sample of said c...
02/01/2011
7879244Method for anion-exchange adsorption and thioether anion-exchangers
A method for the removal of a substance, which has a negative charge and which is present in an aqueous liquid (I). The method comprises the steps of: (i) contacting the liquid with an anion-exchanger (1) that comprises mixed mode anion-exchanging ligands in which t...
02/01/2011
7834158Mutated immunoglobulin-binding protein
The present invention relates to an immunoglobulin-binding protein, wherein at least one asparagine residue has been mutated to an amino acid other than glutamine or aspartic acid, which mutation confers an increased chemical stability at pH-values of up to about 13...
11/16/2010
7824924Analytical measuring and evaluation method for molecular interactions
The invention relates to an analytical measuring and evaluation method for determining the interaction parameters between an analyte and a ligand, preferably in a biosensor. According to the inventive method, the concentration of the analyte is gradually changed at ...
11/02/2010
7822568Method and apparatus for quantitating surface-binding optical resonance profiles
Empirical profile curve fits (260) are used to quantitative the surface optical resonance profiles (268) using two EPF stages of calibration and fit. The calibration surface binding optical resonance scan is obtained with fine angle or wavelength spaci...
10/26/2010
7820042Method for removing air from a chromatography column
The invention relates to a method for removing air from the bed space of a chromatography column. The method involves use a chromatography column having an inner wall which comprises at least one elongated groove through which air can pass from the bed space to a ch...
10/26/2010
7819953Air trap
The invention relates to air traps 13, particularly for chromatography systems, chromatography systems using such air traps and methods of using such chromatography systems, in which the air trap comprises a liquid inlet pipe 33, a liquid outlet pipe
10/26/2010
7811515Method and device for laminar flow on a sensing surface
Methods and devices are provided for controlling a fluid flow over a sensing surface within a flow cell. The methods employ laminar flow techniques to position a fluid flow over one or more discrete sensing areas on the sensing surface of the flow cell. Such methods...
10/12/2010
7811435Method for scanning gels and gel folder for use in the method
The present invention relates to a method of scanning an electrophoretic gel after electrophoresis of fluorescence labelled samples, comprising inserting the gel into a separate low fluorescent scanning unit, in the shape of a gel folder or a frame, and scanning the...
10/12/2010
7785473Chromatography column and method of maintenance
A chromatography column and method of maintenance is described which does not require the use of a hoist or crane for disassembly. The method provides improved operator safety by reducing the need for the operator to work below a suspended or supported load within t...
08/31/2010
7780853Method for conducting maintenance on a chromatography column
The present invention relates to methods for conducting maintenance on chromatography columns used in industrial-scale chromatography. In particular, the invention is concerned with safer methods for performing maintenance on such columns, such as cleaning and repla...
08/24/2010
7750129Process for the purification of antibodies
The present invention relates to a process for the purification of antibodies from one or more impurities in a liquid, which process comprises contacting said liquid with a first chromatography resin comprised of a support to which multi-modal ligands have been immo...
07/06/2010
1        
 
Sign InRegister
Username  
Password   
forgot password?