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Assignee: Fuso Pharmaceutical Industries, Ltd.


Location: Osaka, JP
No. of patents: 34

NumberTitleIssue Date
8168408Cytolethal distending toxins and detection of bacteria using the same as a target
The present inventors succeeded in cloning the CDT genes of C. coli and C. fetus, which were previously unknown, and in determining their sequences. In addition, the inventors also developed specific primers and primers common to the two species by com...
05/01/2012
8084578Monoclonal antibody against human scavenger receptor SRCL-P1
Novel scavenger receptors having an SR structure and a collectin-like structure are provided, which can be utilized in the elucidation of mechanisms of macrophage and basic immunity; in the elucidation of mechanisms of the development of a wide variety of diseases s...
12/27/2011
7985833Collectin
Provided are isolated collectin (CL-L2s) genes including a base sequence set out in SEQ ID NO: 1, 3, 5, 7, 9, 12, 36, 38 or 40 relating to a novel collectin which are expected to exhibit an antibacterial activity, an antiviral activity and the like particularly in a...
07/26/2011
7358061Methods of diagnosing thyroid carcinoma
Antibodies to a LAR phosphatase subunit, particularly antibodies having specificity to an intracellular domain of a phosphatase subunit, methods for generation thereof and cells producing these antibodies, and determination and examination methods of LAR/LAR derived...
04/15/2008
7351541Method for diagnosing a renal disorder
Methods for diagnosing renal disorder, hemolytic uremic syndrome and enterohemorrhagic E. coli infectious disease at an early stage, and for diagnosing the severity of these diseases are provided. Detection of excretion of AQP2 and/or molecules derived theref...
04/01/2008
7348306Composition for promoting lacrimal secretion
A composition for promoting lacrimal secretion which can be used safely and effectively in the lacrimal secretion promoting therapy, not in the conventional supplemental therapy of lacrimal fluid components is provided. The composition comprises a component which ac...
03/25/2008
7282579Serine protease BSSP6
There are provided a polynucleotide encoding human BSSP6 serine protease and a vector and transformed host cells containing this human BSSP6 serine protease encoding polynucleotide. ...
10/16/2007
7247435Enzymatic fluorometric assay for cAMP and adenylate cyclase
The present invention relates to a method for quickly determining cAMP content or an adenylate cyclase activity in a biological sample containing non-cyclic adenine nucleotides without the use of radioactive agents. Particularly, the present invention provide...
07/24/2007
7211425Serine protease BSSP4
There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8, 10, 12, 14, 16, 18 and 20; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino a...
05/01/2007
7189809Scavenger receptors
Novel scavenger receptors having an SR structure and a collectin-like structure are provided, which can be utilized in the elucidation of mechanisms of macrophage and basic immunity; in the elucidation of mechanisms of the development of a wide variety of diseases s...
03/13/2007
7029909Protein expression vector and utilization thereof
A protein expression vector containing (a) a nucleotide sequence encoding an IgG(κ) or a trypsin secretory signal peptide, (b) a nucleotide sequence encoding a polyhistidine amino acid sequence, (c) a nucleotide sequence encoding an amino acid sequence comprising a...
04/18/2006
6979727Recombinant conglutinin and producing method thereof
A recombinant conglutinin which contains a collagen region consisting of six amino acids containing two amino acid sequences Gly-Xaa-Xaa (SEQ ID NO:3, wherein Xaa stands for a protein-constituting amino acid), the neck region of natural conglutinin and the sugar cha...
12/27/2005
6933135Antibodies specific for intracellular domain of protein tyrosine phosphatase
Antibodies to intracellular domains of two or more kinds of protein tyrosine phosphatases, methods for generation thereof and cells producing these antibodies are disclosed. The antibody of the present invention may have specificity to intracellular domains of phosp...
08/23/2005
6921658Serine protease BSSP6
There are provided a human BSSP6 serine protease and a pharmaceutical composition containing this serine protease. Also provided is an antibody to this serine protease or to a fragment thereof. ...
07/26/2005
6908756Serine protease BSSP2
There are provided proteins having the amino acid sequences represented by SEQ ID NOS: 2, 4, 6, 8 and 10; proteins having amino acid sequences derived from these amino acid sequences by deletion, substitution or addition of one to several amino acids; and nucleotide...
06/21/2005
6846912Antibody against LAR phosphatase subunit
Antibodies to a LAR phosphatase subunit, particularly antibodies having specificity to an intracellular domain of a phosphatase subunit, methods for generation thereof and cells producing these antibodies, and determination and examination methods of LAR/LAR derived...
01/25/2005
6660852Probe for diagnosing infectious diseases
A probe derived from bacteria of pneumonia, containing fragments of DNA which streptococcus pneumoniae essentially possesses, and useful for detecting and identifying causative bacteria of pneumonia is obtained by completely digesting the DNA with a restr...
12/09/2003
6645734Serine protease specific monoclonal antibodies and their use
A monoclonal antibody binding selectively to neurosin obtained from hybridomas, in particular, strain 2B2-6 and strain S2E5 showing stable proliferation ability. These hydridomas are obtained by fusing mouse spleen cells having a high antibody titer again...
11/11/2003
6365342Methods for detecting anti-viral activity of calcium-dependent lectins
A recombinant conglutinin which contains a collagen region consisting of six amino acids containing two amino acid sequences Gly-Xaa-Xaa (SEQ ID NO:3, wherein Xaa stands for a protein-constituting amino acid), the neck region of natural conglutinin and th...
04/02/2002
6265568Probes for the diagnosis of infections caused by bacteroides fragilis
The DNA from the bacteria Bactereoides fragilis is extracted, then completely digested with restriction enzyme HindIII, followed by cloning into a suitable vector to select a probe comprising DNA which is essentially contained in Bacteroides fragilis, the...
07/24/2001
6245906Probes for the diagnosis of infections caused by Streptococcus pyogenes
The DNA from the bacteria Streptococcus pyogenes is extracted, then completely digested with restriction enzyme HindIII, followed by cloning into a suitable vector to select a probe comprising DNA which is essentially contained in Streptococcus pyogenes, ...
06/12/2001
6172215Probes for detecting and identifying Helicobacter pylori
DNA probes for detecting the presence of Helicobacter pylori are provided. These isolated, purified oligonucleotide probes are useful in assays for the specific detection of Helicobacter pylori because they specifically hybridize to the DNA of H. pylori....
01/09/2001
6130086Composition for an in vitro fertilization medium
The present invention aims to provide a medium composition for in vitro fertilization, in particular, a composition usable in the culture of ova or early embryos which are fertilized eggs, the preparation or culture of sperm, and the pre-treatment of ova ...
10/10/2000
6110708Recombinant conglutinin and producing method thereof
A recombinant conglutinin containing a collagen region comprising six amino acid residues containing two amino acid sequences Gly-Xaa-Xaa (SEQ ID) NO:3, Xaa representing a protein-constituting amino acid residue), a neck region of natural conglutinin and ...
08/29/2000
5853998Probe for diagnosing Enterococcus faecalis
DNA probes for diagnosing infectious diseases involving Enterococcus faecalis and methods of using such probes are provided....
12/29/1998
5824474Method for detecting nucleic acid
A method of detecting a nucleic acid which comprises bringing a solid carrier suspected to carry or contain a nucleic acid into contact with a polyamine to which a label capable of generating a detectable signal or a precursor thereof is bound, to form a ...
10/20/1998
5807673Probe for diagnosing infectious disease
DNA probes for diagnosing infectious diseases involving Staphylococcus aureus and methods of using such probes are provided....
09/15/1998
5770375Probe for diagnosing staphylococcus epidermidis
DNA probes for diagnosing infectious diseases involving Staphylococcus epidermidis and methods of using such probes are provided....
06/23/1998
5763188Probe for diagnosing Escherichia coli, Klebsiella pneumonieae or Enterobacter cloacae
DNA probes for diagnosing infectious diseases involving Escherichia coli, Klebsielkli pneunmoniae or Enterobacter cloacae and methods of using such probes are provided....
06/09/1998
5708159Probe for diagnosing infectious diseases which hybridizes with DNA from candida albicans
The invention provides a probe useful for rapidly detecting and identifying fungi causative of infectious diseases by digesting completely a DNA extracted from a fungus, e.g., Candida albicans, with EcoRI, inserting the same into an appropriate cloning ve...
01/13/1998
5656112Synthetic resin container including a mouthpiece sealed by a closure and a method for sealing the same
A synthetic resin container including a mouthpiece sealed by a closure is to be used for medical drip infusion or the like. The closure has a tight-sealing synthetic resin stopper, and a leakage preventing rubber stopper for preventing liquid leakage when...
08/12/1997
5232834Anti-human sperm antibody, and its production and use
A monoclonal or polyclonal antibody having a specific binding property to an antigenic site on the human sperm acrosome, which is produced by a hybridoma obtained by fusion between an antibody-producing mammalian (except human) cell immunized with the ant...
08/03/1993
4984415Method and apparatus for blockading an opening through a cylindrical mouthpiece of a synthetic resin container
There is disclosed a simply constructed apparatus for and a ready method of blockading a mouthpiece of a transfusion synthetic resin container used for medical drip infusion. Based on the apparatus and the method thereof, insertion of an instillation need...
01/15/1991
4929479Medical bag
A medical bag composed of a laminate comprising (i) an inner low-density polyethylene layer, (ii) an intermediate layer of ethylene-vinyl acetate copolymer, ethylene-propylene type elastomer, or ethylene-butene-1 type elasomer, and (iii) an outer low-dens...
05/29/1990
 
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