Assignee: Fujisawa Pharmaceutical Co., Ltd.

Location: Osaka, JP
No. of patents: 822

«First «Previous1 2 3 4 5 6 7 8 9 10 11 Next»Last»

Number	Title	Issue Date
7060721	Imidazole compounds and medicinal use thereof Imidazole compounds represented by general formula (I): wherein each symbol is as defined in the specification, and salts thereof, and a pharmaceutical composition containing same are provided. These compounds ar...	06/13/2006
7029860	Amyloid-β protein aggregation-regulating factors The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-β protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-β prote...	04/18/2006
6979461	Method for producing liposome preparation An object of the present invention is to provide a method for producing a liposome preparation having excellent rapid action and excellent redispersion into aqueous medium. The present invention provides a method for producing a liposome preparation by vacuum drying...	12/27/2005
6967197	Thiazepinyl hydroxamic acid derivatives as matrix metalloproteinase inhibitors A compound of formula (I) in which R1 is halo, lower alkoxy, optionally substituted aryl, optionally substituted aryloxy, optionally substituted heterecyclic group or optionally substituted lower alkynyl, R2 is amidated carboxy, R3 i...	11/22/2005
6960435	Amyloid β protein agglutination-controlling factor The present invention provides: proteins suppressing or promoting the aggregation or deposition of amyloid-β protein; polynucleotides encoding the proteins; a method for screening a compound suppressing or promoting the aggregation or deposition of amyloid-β prote...	11/01/2005
6927230	Triazole derivatives A compound of the formula (I): wherein R1 is lower alkyl which is optionally substituted with halogen, cyano, N,N-di(lower)alkylcarbamoyl,	08/09/2005
6924278	Aroyl-piperazine derivatives, their preparation and their use as tachykinin antagonists This invention relates to piperazine derivatives of the formula: wherein each symbol is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical c...	08/02/2005
6911469	Sulfonamide compounds and pharmaceutical use thereof A sulfonamide compound of the formula (I): R1—SO2NHCO—A—X—R2 (I) wherein R1 is alky, alkenyl, alkynyl and the like; A is an optionally substitutedheteropolycyclic group except benzimidazol...	06/28/2005
6908940	Imidazole compounds and their use as adenosine deaminase inhibitors Imidazole compounds having adenosine deaminase inhibitory activity represented by the formula (I) wherein R1 is aryloxy, or aryl which is optionally substituted with suitable substituent(s); R2 is lower alkyl; R3 is hydroxy or protec...	06/21/2005
6890934	Sulfonamide compounds and uses thereof as medicines The present invention relates to a sulfonamide compound of the formula (I): wherein each symbol is as defined in the specification, a salt thereof, and a pharmaceutical composition containing same. This compound can be...	05/10/2005
6890909	Brain-protective agent A brain-protective agent containing an NF-κB decoy. In brain diseases, the brain can be particularly effectively protected against brain disorders (for example, cerebral vasospasm following a subrachnoidal hemorrhage and apoptosis of the nerve cells following a cer...	05/10/2005
6884868	Cyclic hexapeptides having antibiotic activity This invention relates to new polypeptide compound represented by general formula (I), wherein R1, R2, R3, R4, R5 and R6 are as defined in the description or a salt thereof which has antimicrobial act...	04/26/2005
6884433	Sustained release formulation containing tacrolimus Sustained release formulation containing tacrolimus or its hydrate is provided. The time (T63.2%) required for 63.2% of the maximum amount of tacrolimus or its hydrate to be dissolved is 0.7 to 15 hours. The time is measured in accordance to the Japanes Pharmacopoci...	04/26/2005
6881341	Method for separating lactone-containing high-molecular weight compounds A method for separating a lactone-containing high-molecular weight compound comprising subjecting a mixture of a lactone-containing high-molecular weight compound having, as its side-chain, at least one of a lower alkenyl group and a lower alkoxy group and its analo...	04/19/2005
6878827	Process for producing anhydride of aminothiazole derivative This invention provides a novel industrial process for preparation of an anhydride of 2-(2-aminothiazole-4-yl)-2-hydroxy compound. ...	04/12/2005
6869950	Benzimidazole derivatives The present invention provides novel benzimidazole derivatives of the following formula (I) and salts thereof: wherein R1 represents a lower alkyl group or a lower alkyloxy-lower alkyl group; R2 r...	03/22/2005
6833353	Use of immunosuppressants for MMP mediated diseases A new use of immunosuppressant for treating or preventing MMp-medicated diseases is provided. The preferred immunosuppresants are tacrolimus, cyclosporing A or 33-epi-chloro-33-desoxyascomycin (pimecrolimus). Particularly, preferable MMP-mediated diseases are the di...	12/21/2004
6826033	Aminoalcohol derivatives The present invention relates to a compound formula (I) wherein X1 is bond or —O—CH2—, (II) or (III) R1 is hydrogen or an amino protective group, a is phenyl, indolyl or carbazolyl, each of which may be substituted with one or ...	11/30/2004
6825003	Cyclic lipopeptide acylase The present invention provides a cyclic lipopeptide acylase which may effectively deacylate the acyl side chain of a cyclic lipopeptide compound, specifically FR901379 Substance or its analog thereof shown by the following general formula [I], and a process for prod...	11/30/2004
6825200	Substituted dipeptides having nos inhibiting activity The present invention a compound represented by the formula (I): where the structural variables R1-R6 are defined herein. ...	11/30/2004
6812235	Beta-alanine derivatives and their use as receptor anatgonists A beta-alanine derivative of the formula (I) wherein R1 is hydrogen atom or an amino protective group; A is a lower alkylene group or a lower alkenylene group; R2 is hydrogen atom or an amino group which may be substituted with an acyl group; R...	11/02/2004
6787543	Benzhydryl derivatives A compound of the formula (I): in which Z, R1, R2, R8, R10, R11, R12, R13 and R14 are each as defined in the description, or a salt thereof. The object compound of the present in...	09/07/2004
6787565	Sulfonamide compounds and pharmaceutical use thereof A sulfonamide compound of the formula (I): R1—SO2NHCO—A—X—R2 (I) wherein R1 is alky, alkenyl, alkynyl and the like; A is an optionally substitutedheteropolycyclic group except ...	09/07/2004
6774104	Stabilized pharmaceutical composition in lyophilized form A stabilized pharmaceutical composition in lyophilized form comprising: a cyclic polypeptide compound represented by the general formula (I): wherein R1 is a hydrogen atom or an acyl group and R2 an...	08/10/2004
6770667	Amide compounds The present invention is a compound and pharmaceutical composition comprising a compound of formula (I): wherein R1 is a 4-(lower) alkyl-imidazol-1-yl or a 4,5-di(lower) alkyl-imidazol-1-yl group, R2	08/03/2004
6743776	Cyclohexapeptides having antimicrobial activity This invention relates to new polypeptide compounds represented by general formula [I]: wherein R1 and R2 are as defined in the description and pharmaceutically acceptable salt thereof which ...	06/01/2004
6730776	WF14573 or its salt, production thereof and use thereof The present invention provides a new antimicrobial compound WF14573, and a process for producing WF14573 by (a) culturing a WF14573A and/or B-producing microorganism in a nutrient medium and recovering WF14573A and/or B from the resultant cultured broth or (b) deacy...	05/04/2004
6727245	Heterobicyclic derivatives Heterobicyclic derivatives of the formula: wherein R1 is aryl which may have suitable substituent(s), ar(lower)alkyl which may have suitable substituent(s), halo(lower)alkyl, protected carboxy(lower)alk...	04/27/2004
6718910	Agents for promoting fattening of animals and method of promoting fattening Agents for promoting fattening of animals which contain as the active ingredient(s) at least one member selected from among acids originating in hexoses, non-toxic salts thereof and intramolecular esterification products thereof; and a method of promoting fattening ...	04/13/2004
6709378	Supernatant liquid collector with balance weight forming function and centrifugal apparatus using the same Primaiy supernatant liquid collector 1 allows blood A to separate into a primary supernatant liquid B and red blood cells by leaving the blood A stationary for a prescribed period of time, and then it discharges the primary supernatant liquid B and physiologi...	03/23/2004
6710043	Amide compounds This invention relates to amide compounds having the potentiation of the cholinergic activity and represented by formula (I) wherein R1 is acyl, R2 is lower alkyl, A is a single bond, —CO— or �...	03/23/2004
6703410	Crystal forms of 3-(2,4-dichlorobenzyl)-2-methyl-n-(pentylsulfonyl)-3h-benzimidazole-5-carb oxamide 3-(2,4-Dichlorobenzyl)-2-methyl-N-(pentylsulfonyl)-3H-benzimidazole-5-carbo xamide, a compound having hypoglycemic activity or PDE5 inhibitory effect, has three forms of crystal forms that are distinguishable by their X-ray powder diffraction values. The m...	03/09/2004
6673807	Immunosuppressive imidazole derivatives and their combination preparations with tacrolimus or cyclosporins Methods for increasing graft survival time comprising administering the combination of a compound that inhibits the production of nitric oxide and a compound that is a tricyclic macrolide, such as tacrolimus....	01/06/2004
6673808	Medicinal compositions To provide a pharmaceutical composition comprising a macrolide compound, such as tricyclic compound (I) or its pharmaceutically acceptable salt, a dissolution/absorption promoter, a pharmaceutical base, and optionally a compatibilizing agent and/or a thic...	01/06/2004
6662113	Digital correlation of test samples and the screening of interactions between the same A method for determining the physical, chemical, or biological correlation between test samples in group A and test samples in group B. This correlation can be determined by contacting a mixture of test samples selected according to a certain rule from gr...	12/09/2003
6656905	Cyclic tetrapeptide compound and use thereof A cyclic tetrapeptide compound and use thereof. Especially, a compound WF27082, a process for production of the compound by culturing, in a nutrient medium, a WF27082-producing strain belonging to Acremonium and recovering the compound from a culture brot...	12/02/2003
6630338	Removing deacetylase contaminant from cephalosporin C acylase using cationic surfactant An enzyme in a mixture containing the enzyme and a contaminant enzyme is purified by selectively aggregating and precipitating the contaminant enzyme with a surfactant. A deacetylase contaminant is separated from Cephalosporin C acylase using a cationic s...	10/07/2003
6627792	Human T cell-engrafted mouse, method for developing same and use thereof The present invention provides a method for developing a human T cell-engrafted mouse, which includes transplanting a human-derived bone tissue into an inbred line mouse deficient in immune cells, and a human T cell-engrafted mouse obtainable by the metho...	09/30/2003
6613572	Agent for expression of long-term potentiation of synaptic transmission comprising compound having brain somatostatin activation property The present invention relates to an agent for the expression of long-term potentiation of synaptic transmission, which contains a compound having a brain somatostatin activation property as an active ingredient and to a screening method of an agent for th...	09/02/2003
6610748	Preventives/remedies for skin aging A composition for prophylaxis and therapy of dermal aging which comprises a substance having human leukocyte elastase inhibitory activity as an active ingredient....	08/26/2003

«First «Previous1 2 3 4 5 6 7 8 9 10 11 Next»Last»

PatentStorm

Bizarre Patents

PatentStorm News

Assignee: Fujisawa Pharmaceutical Co., Ltd.