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Assignee: Fluidigm Corporation


Location: South San Francisco, CA
No. of patents: 27

NumberTitleIssue Date
7666361Microfluidic devices and methods of using same
A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at th...
02/23/2010
7640947Microfabricated fluidic circuit elements and applications
Microfabricated fluidic devices of the present invention include switches that can be opened and closed to allow or block the flow of fluid through a channel in response to the pressure level in a gate of the switch. The microfabricated fluidic switches may be coupl...
01/05/2010
7604965Thermal reaction device and method for using the same
An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods pro...
10/20/2009
7588672Optical lens system and method for microfluidic devices
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluo...
09/15/2009
7583853Image processing method and system for microfluidic devices
A method for processing an image of a microfluidic device. The method includes receiving a first image of a microfluidic device. The first image corresponds to a first state. Additionally, the method includes receiving a second image of the microfluidic device. The ...
09/01/2009
7526741Microfluidic design automation method and system
The present invention generally relates to microfluidics and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention a microfluidic circuit design method is prov...
04/28/2009
7476363Microfluidic devices and methods of using same
An M×N matrix microfluidic device for performing a matrix of reactions, the device having a plurality of reaction cells in communication with one of either a sample inlet or a reagent inlet through a via formed within an elastomeric block of the device. Methods pro...
01/13/2009
7442556Microfluidic-based electrospray source for analytical devices with a rotary fluid flow channel for sample preparation
This invention provides microfluidic devices and methods for using the same. Microfluidic devices of the present invention comprises a first elastic layer, a fluid flow channel within the elastic layer; and a means for providing a fluid sample from the fluid flow ch...
10/28/2008
7392827Microfabricated fluidic circuit elements and applications
The present invention provides microfabricated fluidic systems and methods. Microfabricated fluidic devices of the present invention include switches that can be opened and closed to allow or block the flow of fluid through a channel in response to the pressure leve...
07/01/2008
7368163Polymer surface modification
The present invention is directed to a surface modified polymer comprising a surface which is covalently bonded to a surface modifying compound. Formation of the covalent bond between the polymer and the surface modifying compound is achieved by a reaction between a...
05/06/2008
7312085Microfluidic particle-analysis systems
The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipulation and/or detection of particles, such as cells and/or beads. The invention provides systems, including apparatus, methods, and kits, for the microfluidic manipula...
12/25/2007
7307802Optical lens system and method for microfluidic devices
An apparatus for imaging one or more selected fluorescence indications from a microfluidic device. The apparatus includes an imaging path coupled to least one chamber in at least one microfluidic device. The imaging path provides for transmission of one or more fluo...
12/11/2007
7291512Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
A valve structure comprises an elastomeric block formed with first and second microfabricated recesses separated by a membrane portion of the elastomeric block. The valve is actuated by positioning a compliant electrode on a first side of the first recess proximate ...
11/06/2007
7279146Crystal growth devices and systems, and methods for using same
High throughput screening of crystallization of a target material is accomplished by simultaneously introducing a solution of the target material into a plurality of chambers of a microfabricated fluidic device. The microfabricated fluidic device is then manipulated...
10/09/2007
7217367Microfluidic chromatography
The present invention is directed to a microfluidic chromatography apparatus comprising a microfabricated fluid delivery system and a chromatography column which is in fluid communication with the fluid delivery system, and a method for producing and using the same....
05/15/2007
7118910Microfluidic device and methods of using same
A variety of elastomeric-based microfluidic devices and methods for using and manufacturing such devices are provided. Certain of the devices have arrays of reaction sites to facilitate high throughput analyses. Some devices also include reaction sites located at th...
10/10/2006
7075162Electrostatic/electrostrictive actuation of elastomer structures using compliant electrodes
A valve structure includes an elastomeric block formed with first and second microfabricated recesses separated by a membrane portion of the elastomeric block. The valve is actuated by positioning a compliant electrode on a first side of the first recess proximate t...
07/11/2006
7059348Drug delivery system
An implantable drug delivery system has a housing, a collapsible reservoir, a microfabricated flow channel, and at least one magnet. The collapsible reservoir is disposed in the housing. The microfabricated flow channel is connected at one end to the collapsible res...
06/13/2006
7062418Computer aided design method and system for developing a microfluidic system
The present invention generally relates to design automation techniques and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention the system includes a synthes...
06/13/2006
7005493Polymer surface modification
The present invention is directed to a surface modified polymer comprising a surface which is covalently bonded to a surface modifying compound. Formation of the covalent bond between the polymer and the surface modifying compound is achieved by a reaction between a...
02/28/2006
6953058Microfabricated fluidic circuit elements and applications
The present invention provides microfabricated fluidic systems and methods. Microfabricated fluidic devices of the present invention include switches that can be opened and closed to allow or block the flow of fluid through a channel in response to the pressure leve...
10/11/2005
6951632Microfluidic devices for introducing and dispensing fluids from microfluidic systems
The present invention provides microfluidic devices, systems and methods for using the same, which facilitate the introduction of fluid to and from a microfluidic channel located within the microfluidic devices. ...
10/04/2005
6885982Object oriented microfluidic design method and system
The present invention provides for the design of a microfluidic system, including a microfluidic chip or circuit, using an object oriented microfluidic computer aided design system. In an embodiment of the present invention, in a computer system having a computer me...
04/26/2005
6829753Microfluidic design automation method and system
The present invention generally relates to microfluidics and more particularly to the design of customized microfluidic systems using a microfluidic computer aided design system. In one embodiment of the present invention a microfluidic circuit design method is prov...
12/07/2004
6802342Microfabricated fluidic circuit elements and applications
The present invention provides microfabricated fluidic systems and methods. Microfabricated fluidic devices of the present invention include switches that can be opened and closed to allow or block the flow of fluid through a channel in response to the pressure leve...
10/12/2004
6752922Microfluidic chromatography
The present invention is directed to a microfluidic chromatography apparatus comprising a microfabricated fluid delivery system and a chromatography column which is in fluid communication with the fluid delivery system, and a method for producing and using the same....
06/22/2004
D488818Fluidic rotary mixer square icon for a display screen
04/20/2004

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