Assignee: Fisons plc

Location: Ipswich, GB2
No. of patents: 81

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Number	Title	Issue Date
RE38628	Pharmaceutical compositions A method of treatment of a condition selected from the group comprising conjunctivitis, keratitis, ‘allergic eyes’, adenovirus infections, corneal homograft rejection, anterior uveitis, nasal polyps, vasomotor rhinitis, allergic manifestations of the nasopharynx...	10/19/2004
5846521	Pressurized solvent-free drug aerosol compositions containing hydrofluorocarbon propellants Pressurised aerosol compositions comprise a medicament, a hydrofluorocarbon propellant and a polyethoxylated surfactant, the compositions containing substantially no solvent, other than the propellant, capable of increasing the solubility of the surfactan...	12/08/1998
5682875	Aerosol device having a spout to prevent spray head blockage An aerosol inhalation device suitable for use in association with a pressurized medicament container having a valve stem has a spray head adapted to receive the valve stem. The spray head has an outlet orifice of uniform diameter which is provided with a ...	11/04/1997
5670167	Process for the production of medicament formulations A medicament compact is produced by placing loose powdered medicament in a mould having a longitudinal axis where a mandrel is positioned along the longitudinal axis of the mould compressing the medicament when a force parallel to the longitudinal axis is...	09/23/1997
5628307	Medicament inhalation device and formulation A device for the administration by inhalation of a medicament in powdered form comprises a medicament reservoir (3) and metering means for dispensing a dose of medicament from the reservoir (3), characterized in that the reservoir (3) comprises a compacte...	05/13/1997
5615670	Powder inhaler with centrifugal force used to meter powder A device for the administration by inhalation of a medicament in dry powder form comprises a medicament reservoir (9) and a medicament metering system (10) including a metering chamber (23) communicable with the reservoir (9), characterized in that the re...	04/01/1997
5572024	Apparatus and method for isotopic ratio plasma mass spectrometry The invention comprises a method and apparatus for inductively-coupled plasma mass spectrometry which is particularly suitable for the determination of isotopic ratios. In order to improve the precision of such determinations, the nozzle-skimmer type inte...	11/05/1996
5561292	Mass spectrometer and electron impact ion source thereof An enclosed ion source for generating substantially monoenergetic ions from a gaseous sample comprises a chamber into which the gaseous sample is introduced and which is substantially enclosed by a source block having two electron entrance apertures forme...	10/01/1996
5538999	Medicament inhalation device and formulation A compacted body of powdered medicament for use in a device for the administration by inhalation of a medicament in powdered form. The compacted body is made by compressing a loose powder containing the medicament in powdered form under pressure to create...	07/23/1996
5532170	Processing analytical reagents A method of preparing functionalized particles including (a) treating an activated substrate (CPG) with a bifunctional cross-linking agent containing a cleavable bond so as to immobilize the cross-linking agent, (b) conjugating an activated particle (P) w...	07/02/1996
5519049	Macrolides for the treatment of reversible obstructive airways diseases Compositions comprising certain macrolides are disclosed which are useful in methods for the treatment of reversible obstructive airway diseases, particularly asthma....	05/21/1996
5514868	Reducing interferences, in plasma source mass spectrometers A method and apparatus for determining the elemental composition of a sample (1) by plasma mass spectroscopy comprises introducing a said sample (1) into an inductively-coupled or microwave-induced plasma formed in an inert gas to generate atomic ions fro...	05/07/1996
5490497	Inhalation devices with a reduced risk of blockage An elastomeric cap for use in an aerosol inhalation device is disclosed. The cap prevents blockage and the buildup of accretions of medicament on the valve stem of the inhalation device and shields the valve stem from the breath of a user of the inhalatio...	02/13/1996
5482946	Medicament inhalation device and formulation A compacted body of powdered medicament for use in a device for the administration by inhalation of a medicament in powdered form. The compacted body is made by compressing a loose powder containing the medicament in powdered form under pressure to create...	01/09/1996
5478756	Chemical sensor for detecting binding reactions A chemical sensor includes a piezoelectric support (1) capable of supporting a shear horizontal wave provided on its surface with an electrode (2,3). The sensor is characterized in that the surface of the piezoelectric support (1) including the region bea...	12/26/1995
5475023	Aqueous pharmaceutical formulations of sodium cromoglycate A pharmaceutical formulation comprising a substantially clear aqueous solution having a viscosity of less than 10 mPa.s containing 3.5 to 5% w/v of 1,3-bis(2-carboxychromon-5-yloxy)-propan-2-ol, or a pharmaceutically acceptable salt thereof, as active ing...	12/12/1995
5451783	Charged-particle analyser A charged particle analyzer which irradiates a specimen and analyzes charged particles emitted therefrom, for example a photo electron spectrometer, having a flood-source which emits charged particles to neutralize the charge which develops on a specimen....	09/19/1995
5443833	Pharmaceutical compositions A method of treatment of a condition selected from the group comprising conjunctivitis, keratitis, `allergic eyes`, adenovirus infections, corneal homograft rejection, anterior uveitis, nasal polyps, vasomotor rhinitis, allergic manifestations of the naso...	08/22/1995
5428044	Anti-inflammatory 4-aminophenyl derivatives There are disclosed compounds of the formula (I): ##STR1## in which the variables R1, R2, R3, R4, R5, R6, and X are defined in the specification. The compounds are useful as pharmaceut...	06/27/1995
5415842	Surface plasmon resonance analytical device A long-range SPR sensor includes: (a) a source of electromagnetic radiation, (b) an optical structure including a block of material transparent to the electromagnetic radiation, a spacer layer of dielectric material, a metallic layer, and a sensitive laye...	05/16/1995
5406608	X-ray analysis apparatus A device for performing both elemental and structural analysis of a crystalline sample, comprising a polychromatic x-ray source (11); a mounting means (15) for mounting the sample so that it is illuminated with x-rays; one or more fluorescence channels (1...	04/11/1995
5384461	Process for the manufacture of a multipolar elongate-electrode lens or mass filter The method includes the steps of assembling one or more blanks (1) in supporting means (2, 3) so that the or each blank occupies at least the space to be occupied by elongate electrodes and, without disturbing the position of the blanks relative to said s...	01/24/1995
5383019	Inductively coupled plasma spectrometers and radio-frequency power supply therefor The invention provides methods and apparatus for atomic emission spectroscopy and for mass spectrometry which make use of an inductively coupled radio-frequency plasma torch. A radio-frequency power supply supplies energy to a plasma induction coil via re...	01/17/1995
5376663	Macrocyclic compounds Compounds of formula (I), in which [R1 and R2 ], [R3 and R4 ] and [R5 and R6 ] represent a carbon-carbon bond or two hydrogen atoms; R2 additionally represents alkyl; R7, R...	12/27/1994
5376787	Mass spectrometer with adjustable aperture mechanism In a mass spectrometer, an aperture defining a beam path to a particle detector (4) is defined by a fixed aperture (5) and a cover (6) mounted on respective carriage assemblies (50,49) running along a beam 46. When a shaft (36) drives carriage (50), a rod...	12/27/1994
5374563	Surface plasmon resonance device and method of determining biological, biochemical, or chemical analyte A sensor based on the technique of surface plasmon resonance (SPR) comprises an SPR device, a source of electromagnetic radiation from which radiation can be directed onto the device, and a detector to measure the intensity of radiation reflected from the...	12/20/1994
5369035	Method and apparatus for analytical sample preparation In the elemental analysis of an analyte present in a sample by optical or mass spectrometry, a nebulizer sprays the liquid sample into a chamber which has a wall transparent to infra-red radiation. Infra-red radiation from a heater external to the chamber...	11/29/1994
5356631	Pharmaceutical composition Particulate nedocromil sodium with a mass median diameter of from 5 to 10 μm is useful as a medicament for inhalation. The particulate nedocromil sodium of the invention is particularly advantageous in that its dispersion, i.e. the proportion of particles ...	10/18/1994
5354988	Power supply for multipolar mass filter A quadrupole mass filter (1) includes a controllable RF oscillator (7) which follows any drift in the resonant frequency of a resonant circuit means (8), this circuit means (8) amplifying an alternating RF potential from the oscillator (7) and supplying i...	10/11/1994
5352893	Isotopic-ratio plasma source mass spectrometer An isotopic-ratio mass spectrometer comprises an r.f. or microwave induced plasma ion source (1, 2, 3), an electrostatic ion-energy analyzer (75), a magnetic sector ion-momentum analyzer (82) wherein ions are dispersed at a first potential according to th...	10/04/1994
5349944	Inhalation devices with a reduced risk of blockage An aerosol inhalation device, having a mouthpiece (12) and a canister (15) of pressurized hygroscopic medicament, the canister (15) being fitted at one end with a dispensing metering valve; wherein a protective barrier (19) is provided between the dispens...	09/27/1994
5348978	Angiotensin converting enzyme inhibitors Angiotensin converting enzyme inhibitors have the formula Z(CH2)n CHR1 COOCHR2 COOH in which Z is --SR3, --COCHR4 NHCOR5, ##STR1## or --NHCHR7 COOH, R4, R	09/20/1994
5347125	Mass spectrometer having means for observing the radiation emitted when ions collide with a target gas A collision cell for observing the emission spectrum of ions. The substantially enclosed collision cell (8) is bounded by a wall (46), the wall having an entrance aperture (47) and an exit aperture (29) through which an ion beam (5) may be passed to trave...	09/13/1994
5341800	Medicament inhalation device and formulation A method of compacting and administering a powdered inhalation medicament for use in an inhalation device includes compacting a body of loosely powdered inhalation medicament such that the degree of compaction is sufficient to hold the body together solel...	08/30/1994
5334374	Pharmaceutical compositions containing pentamidine Pharmaceutical compositions suitable for administration by inhalation and containing pentamidine, or pharmaceutically acceptable salt thereof, in powder form. Such compositions include pressurized aerosol compositions and nonpressurized power compositions...	08/02/1994
5314827	Isotopic composition analyzer An on-line mass spectrometric method and apparatus for the determination of the isotopic composition of at least oxygen, hydrogen and nitrogen in a compound or mixture of compounds. A mixture contained in syringe 6 is injected through injector 7 on a chro...	05/24/1994
5296816	Integrated circuit sensor and detector and spectrometers incorporating the sensor A sensor for electrical charge fabricated as an integrated circuit and including an electrode (1) for receiving charge, a potential-sensitive switching device (2) for generating a pulse whenever the charge received on the electrode (1) is sufficiently gre...	03/22/1994
5166518	Mass spectrometer with electrostatic energy filter A mass spectrometer comprising ion source means (1) for producing ions characteristic of a sample to be analysed; ion detector means (14) for receiving at least some of said ions; magnetic sector analyzing means (18) and electrostatic analyzing means (8) ...	11/24/1992
5013760	Phenylethylamine derivatives and pharmaceutical use Phenylethylamine derivatives of the formula ##STR1## wherein D1 represents a phenylethyl radical which is substituted with hydroxy and/or alkyl groups, R1 and R2 are hydrogen or alkyl, D2 represents hydrogen, an...	05/07/1991
4935244	Nedocromil sodium compositions and methods for their preparation There is described a pharmaceutical composition comprising nedocromil sodium and liposomes. There is also described an aqueous suspension comprising nedocromil sodium partitioned between a free aqueous phase and a liposome phase. There ae also described a meth...	06/19/1990

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Assignee: Fisons plc