Assignee: Fisons Corporation

Location: Rochester, NY
No. of patents: 21

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Number	Title	Issue Date
5902789	Nasal administration of drugs Compositions and methods for the nasal administration of drugs with reduced nasal irritation are disclosed....	05/11/1999
5607935	2-heterocyclicethylamine derivatives and their use as pharmaceuticals Compounds of formula (I), wherein A represents CH.dbd.CH; Q represents pyrazine having substituents R6 and R7 ; R1 represents H or C1-6 alkyl; R2 represents H, C1-6 alkyl, C3-6 alkeny...	03/04/1997
5502164	Peptide compounds having therapeutic activity Compounds of formula I, ##STR1## wherein M is Met, DMet, MeMet, MetO, Ahx, DAhx, MeAhx, Leu, MeLeu, Pro, Ile, MeIle, Ala or Lys, G is Gly, DAla, Pro, Ala, 댪la or Sar; W is Trp, MeTrp, Ala or Nal; X is Met, MeMet, MetO, Ahx, MeAhx, Leu, MeLeu, ...	03/26/1996
5472968	Spiro[cycloalkylbenzene-1,1'-(1',2',3',4'-tetrahydro-isoquinolines)] having neuroprotective properties Compounds of formula (I), ##STR1## in which R1 and R2, which may be the same or different, represent hydrogen, C1-6 alkyl, R3 and R4 independently represent one or more radicals selected from hyd...	12/05/1995
5455259	Compounds for the treatment of neurodegenerative disorders (S)-଱-phenyl-2-pyridineethanamine, and its pharmaceutically acceptable derivatives, are useful in the treatment of neurodegenerative disorders, and exhibit linear pharmacokinetics....	10/03/1995
5429302	Nebulizing element and device There is provided a nebulizing element suitable for nebulizing a liquid, comprising: a) oscillator means; and b) a cover sheet; the cover sheet being disposed between the oscillator means and the liquid to be nebulized in use; and having a metallic chemically ...	07/04/1995
5382683	2-aminopropanamide derivatives Compounds are provided of the following general structure: ##STR1## wherein B is hydrogen or lower alkyl (C1 -C4), R1 is hydrogen or methyl, R2 is lower alkyl (C1 -C4), phenylmethyl or...	01/17/1995
5334720	Diphenyl-1-(aminoalkyl)-2-piperidinone and -2-pyrrolidinone derivatives having anticonvulsant properties Compounds of the formula I, ##STR1## wherein R1, R2, R3 and R4 independently represent hydrogen, alkyl, phenyl or substituted phenyl with the proviso that two of R1, R2, R3 ...	08/02/1994
5124152	Parenteral formulation of metolazone There are described pharmaceutical compositions comprising aqueous solutions of 7 c l r - ,2,3,4-tetrahydro-2-methyl-3-2-methylphenyl)-4-oxo-6-quinazolinesulfonamid e. ethanol and a cosolvent selected from propylene glycol or polyethylene glycols suit...	06/23/1992
5109017	(2-thienyl)alkylamine derivatives having neuroprotective properties Compounds of the formula I, ##STR1## in which: R1 represents hydrogen or C1-6 alkyl, R2 represents hydrogen, C1-6 alkyl, C3-6 alkenyl, C3-6 alkynyl or C3-6 cycloalkyl, R3	04/28/1992
5075317	Spirofurane derivatives Compounds of general formula I, ##STR1## wherein R1 represents hydrogen or alkyl C1-3, R2 represents hydrogen or alkyl C1-6, n and m are integers from 1 to 3, provided that n+m=4, and one of X and Y represents CH	12/24/1991
5073560	Spiro-isoxazolidine derivatives as cholinergic agents Compounds of general formula I, ##STR1## wherein: A represents (CH2)m optionally substituted by R3, B represents (CH2)n optionally substituted by R4, R1 represents hydrogen, C1	12/17/1991
5047541	2-azacyclocarboxamide derivatives Compounds are provided of the following general structure: ##STR1## wherein A is 2-pyrrolidinyl, 2-piperidinyl or 4-thiazolidinyl and R and R1 are independently selected from hydrogen and methyl. They are useful for providing sedative and ...	09/10/1991
4959219	Coating barriers comprising ethyl cellulose Coatings for individual ion exchange resin particles comprised of (a) ethylcellulose and (b) corn oil or acetylated monoglycerides....	09/25/1990
4912222	Antihistamines related to cyproheptadine 4-Dibenzocycloheptenyl, 4-dibenzocycloheptyl, and 4-dibenzoxepinylpiperidine compounds possessing antihistaminic activity....	03/27/1990
4889941	Synthetic flavonoids as inhibitors of leukotrienes and 5-lipoxygenase 7-[3-[(3,4-dihydroxyphenethyl)amino]-2-hydroxypropoxy]-flavone hydrobromide, and related flavonoids are disclosed to inhibit leukotrienes and 5-lipoxygenase; preferred compounds also inhibit rat anaphylaxis....	12/26/1989
4873241	2-amino-N-(2-phenylindan-2-yl)acetamides useful as anti-epileptics 2-Amino-N-(2-phenylindan-2-yl)acetamides of the following formula are provided ##STR1## wherein, a=0 to 3, R1, R2 and R3 are independently selected from hydrogen and methyl, R4 is hydrogen or C1 ...	10/10/1989
4871862	଱-Substituted ketonitrone derivatives ଱-Substituted ketonitrone derivatives containing substituents selected from hydrogen, phenyl, substituted phenyl, naphthyl, furan, thiophen, imidazolylmethyl and triazolylmethyl are useful as intermediates for the preparation of biologically active ...	10/03/1989
4871872	2-[(2-aminoacetyl)amino]acetamide derivatives Compounds are provided of the following general structure: ##STR1## wherein R1, R2, R3 and R4 are hydrogen or methyl and where R5 and R6 are independently selected from hydrogen or flu...	10/03/1989
4859462	Polymer-treated ion exchange resins Sulfonic acid cationic exchange resin particles which have been treated to improve their coatability with minor amounts of high molecular weight polymers selected from carboxypolymethylene, xanthan gum, and propylene glycol alginate....	08/22/1989
4859461	Coatable ion exchange resins Sulfonic acid cationic exchange resin particles which have been treated to improve their coatability with up to about 20% by weight of a compound selected from hydroxypropylmethyl cellulose, hydroxypropyl cellulose, hydroxypropyl sorbitol, sorbitol, and p...	08/22/1989

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Assignee: Fisons Corporation