"What can be more palpably absurd than the prospect held out of locomotives traveling twice as fast as stagecoaches?"
The Quarterly Review ; March edition, 1825
Make the Most of Our Site
See this month's Top Inventors and Most Cited Patents.
Stay on top of the latest innovations by subscribing to an RSS feed.
Registered users: Manage your profile.
| Number | Title | Issue Date |
| 7704948 | Pharmaceutical composition A stool softener and enteric coated bisacodyl form of a pharmaceutical composition. ... | 04/27/2010 |
| 7652006 | Substituted 1(2H)-phthalazinones and pharmaceutical compositions thereof The invention relates to novel quinazolines and heterocycles which are antagonists or positive modulators of AMPA receptors, and the use thereof for treating, preventing or ameliorating neuronal loss associated with stroke, global and focal ischemia, CNS trauma, hyp... | 01/26/2010 |
| D573175 | Four-in-one pain scale | 07/15/2008 |
| 7393872 | Sodium channel blocker compositions and the use thereof Methods of treating or preventing chronic pain or convulsion are disclosed by administering to an animal a sodium channel blocker and at least one of gabapentin and pregabalin. Also disclosed are pharmaceutical compositions and kits for the treatment or prevention o... | 07/01/2008 |
| 7342017 | 1,2,5-Thiadiazol-3-yl-piperazine therapeutic agents useful for treating pain, depression and anxiety A compound of formula: (wherein X, R1, R3, R4, and R5 are disclosed herein) or a pharmaceutically acceptable salt thereof (a “Thiadiazolylpiperazine Compound”), pharmaceutical... | 03/11/2008 |
| D561821 | Four-in-one pain scale | 02/12/2008 |
| 7279493 | Therapeutic agents useful for treating pain A compound of formula: wherein A, Ar, R3, R6, and m are disclosed herein, or a pharmaceutically acceptable salt thereof (a “Cyanoiminopiperazine Compound”), compositions comprising an ef... | 10/09/2007 |
| 7262194 | Therapeutic agents useful for treating pain A compound of formula: wherein X is S or O and A, R1-R4, n, and m are disclosed herein, or a pharmaceutically acceptable salt thereof (a “Pyridazinylpiperazine Compound”), compositions c... | 08/28/2007 |
| 7229993 | Aryl substituted pyrimidines and the use thereof This invention relates to a method of treating disorders responsive to the blockade of sodium ion channels using novel aryl-substituted pyrimidine compounds of Formula I: or a pharmaceutically acceptable salt, or... | 06/12/2007 |
| D540702 | Analog scale for measuring pain | 04/17/2007 |
| 7169782 | Aryl substituted thiazolidinones and the use thereof This invention relates aryl substituted thiazolidinones of Formula I: or a pharmaceutically acceptable salt, or solvate thereof, wherein R1 and R2, are defined in the specification. The inve... | 01/30/2007 |
| 7157103 | Pharmaceutical formulation containing irritant Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse; and an effective amount of an irritant to impart an irritating sensation to an abuser upon administration of said dosage form after ... | 01/02/2007 |
| 7157462 | Therapeutic agents useful for treating pain A compound of formula: wherein Ar, Ar1, Ar2, R3–R6, R13, m, and t are disclosed herein, or a pharmaceutically acceptable salt thereof (a “Hydroxyiminopip... | 01/02/2007 |
| 7144587 | Pharmaceutical formulation containing opioid agonist, opioid antagonist and bittering agent Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of an opioid analgesic; an opioid antagonist; and a bittering agent in an effective amount to impart a bitter taste to an abuser upon administration of the dosage f... | 12/05/2006 |
| 7141250 | Pharmaceutical formulation containing bittering agent Disclosed in certain embodiments is an oral dosage form comprising a therapeutically effective amount of a drug susceptible to abuse; and an effective amount of a bittering agent to impart a bitter taste to an abuser upon administration of said dosage form after tam... | 11/28/2006 |
| 7129248 | Process for preparing oxycodone hydrochloride having less than 25 ppm 14-hydroxycodeinone In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone. ... | 10/31/2006 |
| 7125884 | N-but-3-enyl norbuprenorphine and its use as analgesic The present invention provides compound having the structure: and pharmaceutically acceptable salts or derivatives thereof, as well as compositions including such compounds. The invention also provides methods of (1) preventing pain, (2) treating pain, (3) inducing ... | 10/24/2006 |
| 7105549 | Aryl substituted pyridines and the use thereof This invention relates aryl substituted pyridines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Ar and R1–R4 are set in the specification. The in... | 09/12/2006 |
| 7083808 | Controlled/modified release oral methylphenidate formulations The invention is directed to oral modified/controlled release methylphenidate formulations which provide a rapid initial onset of effect and a prolonged duration of effect. Preferably, the peak concentration is lower than that provided by the reference standard for ... | 08/01/2006 |
| 7084150 | Analogs and prodrugs of buprenorphine Disclosed are prodrugs and analogs of buprenorphine. ... | 08/01/2006 |
| 7078426 | Aryl substituted pyrazoles, triazoles, and tetrazoles, and the use thereof This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R8 are set in the specification. The invention also ... | 07/18/2006 |
| 7074430 | Controlled release tramadol tramadol formulation A controlled release preparation for oral administration contains tramadol, or a pharmaceutically acceptable salt thereof, as active ingredient. ... | 07/11/2006 |
| 7071335 | 2-pyridinyl-1-piperazine therapeutic agents useful for treating pain A Compound of formula (wherein X is O or S and R1–R5 are disclosed herein) or a pharmaceutically acceptable salt thereof (each being a “Piperazine Compound”), pharmaceutical compositio... | 07/04/2006 |
| 7057722 | Method and apparatus for determining the homogeneity of a granulation during tableting An apparatus for detecting the homogeneity of a pharmaceutical mixture has a hopper for containing a mixture of two or more pharmaceutical components and that is situated within a production line of preparation of a pharmaceutical dosage form. A spectroscope is moun... | 06/06/2006 |
| 7022714 | Aryl substituted benzimidazoles and their use as sodium channel blockers This invention relates aryl substituted benzimidazoles of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein R1, R2, R10 and n are defined in the speci... | 04/04/2006 |
| 7018649 | Felodipine transdermal device and methods A method of effectively treating hypertension in humans is achieved by administering felodipine via a transdermal formulation. Preferably, the transdermal formulation is applied to the skin of the patient and maintained in contact with the skin for at least about 24... | 03/28/2006 |
| 6984664 | Tertiary amino compounds having opioid receptor affinity Disclosed are compounds of the formula (I) wherein R1, R2 R3 R4 R5, R6 and N are as disclosed herein. The compounds are useful for the treatment of chron... | 01/10/2006 |
| 6965108 | Method and apparatus for three dimensional imaging using infrared radiation An infrared three-dimensional imaging system and method in which an object is irradiated by monochromatic radiation in the near-infrared or mid-infrared region of the spectrum. A spectral image is captured for each wavelength in a spectral range by a radiation detec... | 11/15/2005 |
| 6958398 | Methods for making thebaine or its acid salts Methods for making thebaine and an acid salt of thebaine are disclosed herein. In one embodiment, an acid salt of thebaine is made from codeinone or an acid salt of one or more of the following: 8-methoxy-Δ6-dihydrothebaine, codeinone dimethyl ketal, and... | 10/25/2005 |
| 6956038 | Aryl substituted thiazolidinones and the use thereof This invention relates aryl substituted thiazolidinones of Formula I: or a pharmaceutically acceptable salt, or solvate thereof, wherein R1 and R2, are defined in the specification. The invention ... | 10/18/2005 |
| 6921541 | Formulations and methods for providing prolonged local anesthesia A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local an... | 07/26/2005 |
| 6919363 | Aryl substituted pyrazoles, triazoles and tetrazoles, and the use thereof This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R8 are set in the specification. The invention also ... | 07/19/2005 |
| 6872733 | Benzimidazolone compounds Disclosed are compounds of the formula (I): wherein A, B, C, M1-M4, R, R1, R2 and n are as described herein. ... | 03/29/2005 |
| 6867210 | Aryl substituted pyrimidines This invention relates aryl substituted pyridines, pyrimidines, pyrazines and triazines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein A1, A2, A3 | 03/15/2005 |
| 6867222 | Nociceptin analogs A compound of the formula (I), (II), (III) or (IV) wherein Z, A, B, C, R, R1, R2, Q, and n are as described herein. ... | 03/15/2005 |
| 6865444 | Container and method for dispensing transdermal dosage forms The present invention provides a two compartment device (10), and method of use, for the disposal of used transdermal dosage forms (26) and the dispensing of unused transdermal dosage forms (28). The first compartment (12) has a dosage fo... | 03/08/2005 |
| 6825205 | N-substituted hydromorphones and the use thereof This invention relates to N-substituted hydromorphones of Formula I: or a pharmaceutically acceptable salt thereof, wherein R is C1-6 alkyl. These compounds act as μ opioid receptor... | 11/30/2004 |
| 6806294 | Opioid analgesic The invention is relative to a pharmaceutical preparation, especially for oral administration, with at least one active substance and with formulation components influencing the release of active substance, which preparation comprises at least one opiod analgesic as... | 10/19/2004 |
| 6800657 | Substituted 5-oxo-5, 6, 7, 8-tetrahydro-4H-1-benzopyrans Disclosed is a method for treating a disorder responsive to the positive modulation of AMPA receptors in animals suffering therefrom, comprising administering to an animal in need thereof a compound of Formula I: or a ph... | 10/05/2004 |
| D493537 | Analog scale for measuring pain | 07/27/2004 |