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Assignee: Enzon, Inc.


Location: SouthPlainfield, NJ
No. of patents: 5

NumberTitleIssue Date
5264555Process for hemoglobin extraction and purification
Methods are disclosed for separating hemoglobin from erythrocytes by contacting erythrocytes with a hypotonic buffer solution at a rate sufficient to render the release of hemoglobin from said erythrocytes without significant lysis. The hemoglobin is then...
11/23/1993
5260203Single polypeptide chain binding molecules
The invention pertains to a single polypeptide chain binding molecule which has binding specificity and affinity substantially similar to the binding specificity and affinity of the light and heavy chain aggregate variable region of an antibody, to geneti...
11/09/1993
5234903Chemically modified hemoglobin as an effective, stable non-immunogenic red blood cell substitute
The present invention relates to chemically modified hemoglobin produced by a novel and efficient method in which stroma-free hemoglobin is first effectively deoxygenated and reduced and then conjugated with a polyalkylene oxide such as polyethylene glyco...
08/10/1993
5219564Poly(alkylene oxide) amino acid copolymers and drug carriers and charged copolymers based thereon
Copolymers of poly(alkylene oxides) and amino acids or peptide sequences are disclosed, which amino acids or peptide sequences have pendant functional groups that are capable of being conjugated with pharmaceutically active compounds for drug delivery sys...
06/15/1993
5122614Active carbonates of polyalkylene oxides for modification of polypeptides
Poly(ethylene glycol)-N-succinimide carbonate and its preparation are disclosed. Polyethylene glycol (PEG) is converted into its N-succinimide carbonate derivative. This form of the polymer reacts readily with amino groups of proteins in aqueous buffers. ...
06/16/1992
 
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