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| Number | Title | Issue Date |
| 8133989 | Nucleic acid primer/construct compositions This invention provides novel processes for amplifying nucleic acid sequences of interest, including linear and non-linear amplification. In linear amplification, a single initial primer or nucleic acid construct is utilized to carry out the amplification process. I... | 03/13/2012 |
| 6239271 | Energy transfer hybridization assay composition Disclosed is a nucleic acid hybridization assay composition for detecting the presence or absence of a target oligo- or polynucleotide in a sample. The composition comprises: a solid matrix having at least one surface which is substituted with a first int... | 05/29/2001 |
| 5998135 | Energy transfer hybridization assay using intercalators and lanthanide metals Disclosed is a nucleic acid hybridization assay composition for detecting the presence of absence of a target oligo- or polynucleotide in a sample. The composition comprises: a solid matrix having at least one surface which is substituted with a first int... | 12/07/1999 |
| 5989809 | Methods for detecting a polynucleotide using an inactivating reagent and composition and kit comprising same The present invention provides a method for detecting the presence of a target polynucleotide in a sample. The method comprises the steps of (a) contacting the sample under hybridizing conditions with (i) a single-stranded polynucleotide probe capable of ... | 11/23/1999 |
| 5384241 | Specific binding assay compound with inhibitive self-quenching characteristics Disclosed is an assay system including a compound comprising an analyte-specific moiety having substituted thereon a polymer comprising plurality of self-quenching emitter moieties and a plurality of isocharged functionality separating the emitter moietie... | 01/24/1995 |
| 5288609 | Capture sandwich hybridization method and composition This invention provides methods and compositions for the detection of a target genetic material having a desired base sequence or gene. Also disclosed are methods and compositions for the detection of mutants. The methods and compositions are based in par... | 02/22/1994 |
| 5260433 | Saccharide specific binding system labeled nucleotides The present invention provides nucleotides and polynucleotides which are chemically modified or labeled so as to be capable of ready detection when attached to and/or incorporated in nucleic acid material. More particularly, this invention provides a nucl... | 11/09/1993 |
| 5241060 | Base moiety-labeled detectable nucleatide The present invention provides nucleotides and polynucleotides which are chemically modified or labeled so as to be capable of ready detection when attached to and/or incorporated in nucleic acid material. More particularly, this invention provides a nucl... | 08/31/1993 |
| 5175269 | Compound and detectable molecules having an oligo- or polynucleotide with modifiable reactive group A detectable molecule of the formula A3 --(--X--R1 --E--Detb)m where A3 is A2 or a polymer, where A3 has at least one modifiable reactive group selected from the group consisting of amino,... | 12/29/1992 |
| 5061076 | Time-resolved fluorometer A time-resolved fluorometer, having a light tight enclosure, for detecting the presence of an analyte in a sample. Within the light tight enclosure are a pulsed dye laser that produces a pulsed light beam for sample excitation, a light tight sample excita... | 10/29/1991 |
