Assignee: Endorecherche, Inc.

Location: CA
No. of patents: 28

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Number	Title	Issue Date
8168627	Helix 12 directed non-steroidal antiandrogens Compounds having the structure (or their salts): are used to treat or reduce the likelihood of acquiring androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, polycystic ovarian syndrome, acne,...	05/01/2012
7943603	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors Novel methods for the medical treatment and/or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis in susceptible warm-blooded animals including humans involving administration of selective estrogen r...	05/17/2011
7884092	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors Novel methods for the medical treatment and/or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis in susceptible warm-blooded animals including humans involving administration of selective estrogen r...	02/08/2011
7709516	Helix 12 directed non-steroidal antiandrogens Compounds having the structure (or their salts): are used to treat or reduce the likelihood of acquiring androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, polycystic ovarian syndrome, acne,...	05/04/2010
7429576	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors Novel methods for the medical treatment and/or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis in susceptible warm-blooded animals including humans involving administration of selective estrogen r...	09/30/2008
7005428	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors Novel methods for the medical treatment and/or inhibition of the development of hypercholesterolemia in susceptible warm-blooded animals including humans involving administration of selective estrogen receptor modulator particularly compounds having the general stru...	02/28/2006
6995150	Pharmaceutical compositions and uses for androst-5-ene-3β, 17β-diol Androst-5-ene-3β,17β diol is used to treat or reduce the likelihood of acquiring osteoporosis or menopausal symptoms, or other diseases affected by estrogen receptor activity, and for conditions which respond well to DHEA treatment, but where a higher ratio of est...	02/07/2006
6964955	Pharmaceutical compositions and uses for androst-5-ene-3β, 17β-diol Androst-5-ene-3β,17βdiol is used to treat or reduce the likelihood of acquiring osteoporosis or menopausal symptoms, or other diseases affected by estrogen receptor activity, and for conditions which respond well to DHEA treatment, but where a higher ratio of estr...	11/15/2005
6933321	Antiandrogenic biphenyls Biphenyl derivatives are disclosed for use in the treatment of androgen-dependent diseases, such as prostate cancer, benign prostatic hyperplasia, precocious puberty, polycystic ovarian syndrome, acne, hirsutism, seborrhea, androgenic alopecia and premature male bal...	08/23/2005
6884795	Pharmaceutical compositions and uses for androst-5-ene-3β, 17β-diol Androst-5-ene-3β,17β diol is used to treat or reduce the likelihood of acquiring osteoporosis or menopausal symptoms, or other diseases affected by estrogen receptor activity, and for conditions which respond well to DHEA treatment, but where a higher ratio of est...	04/26/2005
6710059	Methods of treating and/or suppressing weight gain Novel methods for the medical treatment and/or prevention of obesity, abdominal fat, and insulin resistance in susceptible warm-blooded animals including humans involves the administration of selective estrogen receptor modulators (SERMs). A combination of a SERM wi...	03/23/2004
6465445	Medical uses of a selective estrogen receptor modulator in combination with sex steroid precursors Novel methods for the medical treatment and/or inhibition of the development of osteoporosis, breast cancer, hypercholesterolemia, hyperlipidemia or atherosclerosis in susceptible warm-blooded animals including humans involving administration of selective...	10/15/2002
6423698	Combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia A combination therapy for the prophylaxis and/or treatment of benign prostatic hyperplasia in susceptible warm-blooded animals which comprises administering a combination of two or more compounds selected from the group consisting of an inhibitor of 5�...	07/23/2002
6287834	Characterization and use of an isolated uridine diphospho-glucuronosyltransferase A uridine diphospho-glucuronosyltransferase (UGTB217) is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using antibodi...	09/11/2001
6124115	Production and use of isolated type 5 17ଲ-hydroxysteroid dehydrogenase A novel type 5 17ଲ-hydroxysteroid dehydrogenase is provided. Methods of producing the enzyme and using the enzyme to identify potential compounds which inhibit or alter the activity of the enzyme are described. In addition, methods of using the gene...	09/26/2000
5840735	Sex steroid activity inhibitors Inhibitors of sex steroid activity, for example those having the general structure ##STR1## may be used as part of a pharmaceutical composition to provide antiestrogenic effects and/or to suppress estrogen synthesis. Such pharmaceutical composit...	11/24/1998
5686437	Estrogen nucleus derivatives for use in the inhibition of sex steroid activity Novel derivatives of estrogenic nuclei, contain a side-chain substitution of the formula --R1 B--R2 --!x L--G and may be used in pharmaceutical compositions as sex steroid activity inhibitors useful in the treatment of b...	11/11/1997
5610150	Method of treatment of androgen-related diseases A method of treatment of androgen-related diseases such as prostate cancer in susceptible male animals, including humans, novel antiandrogens and/or novel sex steroid biosynthesis inhibitors as part of a combination therapy. Sex steroid biosynthesis inhib...	03/11/1997
5593981	Method and treatment of androgen-related diseases A method of treatment of androgen-related diseases such as prostate cancer in susceptible male animals, including humans, comprises administering novel antiandrogens and/or novel sex steroid biosynthesis inhibitors as part of a combination therapy. Sex st...	01/14/1997
5585405	Inhibitors of sex steroid biosynthesis and methods for their production and use Certain steroidal and non-steroidal compounds have been found to inhibit androgen and estrogen formation. Such inhibition may aid in the reduction of the activity of these hormones and may be useful in the treatment of diseases where, for example, inhibit...	12/17/1996
5541172	Controlled release systems and low dose androgens Methods of treatment and prevention of estrogen-related diseases, and of fertility control, include low dose (e.g. less than 50 nanomolar serum concentration) administration of certain anabolic steroids, progestins and other substantially non-masculinizin...	07/30/1996
5494914	Inhibitors for testosterone 5଱-reductase activity Inhibitors of testosterone 5଱-reductase activity, for example those of formula: ##STR1## wherein novel substituents are provided at the R4, R6, R7, R17଱ and/or R17ଲ positions ar...	02/27/1996
5395842	Anti-estrogenic compounds and compositions Inhibitors of sex steroid activity, for example those having the general structure ##STR1## may be used as part of a pharmaceutical composition to provide antiestrogenic effects and/or to suppress estrogen synthesis. Such pharmaceutical composit...	03/07/1995
5372996	Method of treatment of androgen-related diseases A method of treatment of androgen-related diseases such as prostate cancer in susceptible male animals, including humans, comprises administering novel antiandrogens and/or novel sex steroid biosynthesis inhibitors as part of a combination therapy. Sex st...	12/13/1994
5364847	Inhibitors of sex steroid biosynthesis and methods for their production and use Certain steroidal and non-steroidal compounds have been found to inhibit androgen and estrogen formation. Such inhibition may aid in the reduction of the activity of these hormones and may be useful in the treatment of diseases where, for example, inhibit...	11/15/1994
5362720	Methods of treating or preventing breast or endometrial cancer with low dose non-masculinizing androgenic compounds A method of treatment or prevention of breast and endometrial cancer, osteoporosis and endometriosis in susceptible warm-blooded animals comprising administering a low dose of a progestin or other steroid derivative having androgenic activity and low masc...	11/08/1994
5227375	Aromatase inhibitors Novel aromatase inhibitors are disclosed for use in therapeutic preparations for treatment of estrogen-dependent diseases. The compounds are specified 7଱-substituted androstanedione and androstenedione derivatives which show a strong inhibitory acti...	07/13/1993
5204337	Estrogen nucleus derivatives for use in inhibition of sex steroid activity Novel compounds for the inhibition of sex steroid activity for the treatment of both androgen-related and estrogen-related diseases include for example 15- and 16-halo substituted compounds such as: ##STR1## The compounds are characterized by an estr...	04/20/1993

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Assignee: Endorecherche, Inc.