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| Number | Title | Issue Date |
| 7727558 | Polymeric delivery agents and delivery agent compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 06/01/2010 |
| 7700775 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 04/20/2010 |
| 7662771 | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP)-1 compound or a melanocortin-4 receptor (MC4) agonist peptide The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide. ... | 02/16/2010 |
| 7553872 | Compounds and compositions for delivering active agents Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 06/30/2009 |
| 7544833 | Methods for producing N-(8-[2-hydroxybenzoyl]-amino) caprylic acid Disclosed are improved methods for the synthesis of N-(8-[2-hydroxybenzoyl]-amino)caprylic acid. Certain compounds have been found useful for preventing the formation of a colored impurity when included in an ester hydrolysis reaction. Conducting ester hydrolysis in... | 06/09/2009 |
| 7390834 | Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents Cyanophenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration, treatment of disease and preparation are provided as well. ... | 06/24/2008 |
| 7309698 | Compositions for delivering bisphosphonates Compounds and compositions for the delivery of bisphosphonates are provided. Methods of preparation, administration and treatment are provided as well. ... | 12/18/2007 |
| 7297794 | Phenoxy amine compounds and compositions for delivering active agents Phenoxy amine compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 11/20/2007 |
| 7279597 | Phenyl amine carboxylic acid compounds and compositions for delivering active agents Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/09/2007 |
| 7276534 | Carbon-substituted diketopiperazine delivery systems Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions and admini... | 10/02/2007 |
| 7262325 | Method of preparing salicylamides The present invention provides a fast, high yield method for preparing salicylamide intermediates. The method comprises reacting a C4 or higher alkyl ester of salicylic acid or derivative thereof with at least one amine selected from the group consisting ... | 08/28/2007 |
| 7227033 | Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ... | 06/05/2007 |
| 7217703 | 8-(2-hydroxyphenoxy)octyldiethanolamine and salts thereof for delivery of active agents The present invention provides 8-(2-hydroxyphenoxy)octyldiethanolamine) and salts thereof, compositions containing the same and one or more active agents, and methods of administering active agents with the same. The delivery agents of the present invention are well... | 05/15/2007 |
| 7208178 | Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ... | 04/24/2007 |
| 7208483 | Polymeric delivery agents and delivery agent compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 04/24/2007 |
| 7186414 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 03/06/2007 |
| 7151191 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 12/19/2006 |
| 7138546 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 11/21/2006 |
| 7129274 | Phenoxy carboxylic acid compounds and compositions for delivering active agents Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/31/2006 |
| 7125910 | Compounds and compositions for delivering active agents Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 10/24/2006 |
| 7115663 | Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents Cyanophenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration, treatment of disease and preparation are provided as well. ... | 10/03/2006 |
| 7084279 | Oxadiazole compounds and compositions for delivering active agents Oxadiazole compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 08/01/2006 |
| 7071214 | Compounds and compositions for delivering active agents Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 07/04/2006 |
| 7067119 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration and methods of preparation of the modified amino a... | 06/27/2006 |
| 7005141 | Oral drug delivery compositions and methods The present invention relates to an oral drug delivery system, and in particular to modified amino acids and modified amino acid derivatives for use as a delivery system of sensitive agents such as bioactive peptides. The modified amino acids and derivatives can for... | 02/28/2006 |
| 6991798 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 01/31/2006 |
| 6972300 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides, such as rhGH. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration, are provided, and methods of prepar... | 12/06/2005 |
| 6960355 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 11/01/2005 |
| 6916489 | Active agent transport systems Methods for transporting a biologically active agent across a cellular membrane or a lipid bilayer. A first method includes the steps of: (a) providing a biologically active agent which can exist in a native conformational state, a... | 07/12/2005 |
| 6906030 | Carbon-substituted diketopiperazine delivery systems Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions and admini... | 06/14/2005 |
| 6900344 | Method of preparing alkylated salicylamides via a dicarboxylate intermediate The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide via a dicarboxylated salicylamide intermediate. The present invention also relates to dicarboxylic salicylamide delivery agent compounds for ... | 05/31/2005 |
| 6846844 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 01/25/2005 |
| 6699467 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration and methods of preparation of the modif... | 03/02/2004 |
| 6693208 | Compounds and compositions for delivering active agents Amino acid derivative as carrier compounds and compositions which are useful in the delivery of active agents are provided. The active agents can be a peptide, mucopolysaccharide, carbohydrate, or lipid. Methods of administration, including oral administr... | 02/17/2004 |
| 6693073 | Pulmonary delivery of active agents The present invention provides methods for administering an active agent to an animal in need of the agent by the pulmonary route. This method comprises administering via the pulmonary route, a composition comprising (a) an active agent and (b)(i) an acyl... | 02/17/2004 |
| 6663898 | Carbon-substituted diketopiperazine delivery systems Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions... | 12/16/2003 |
| 6663887 | Compounds and compositions for delivering active agents Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.... | 12/16/2003 |
| 6646162 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well.... | 11/11/2003 |
| 6642411 | Compounds and compositions for delivering active agents Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided Methods of administration and preparation are provided as well.... | 11/04/2003 |
| 6627228 | Polymeric delivery agents and delivery agents compounds Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well.... | 09/30/2003 |