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Assignee: Emisphere Technologies, Inc.


Location: Tarrytown, NY
No. of patents: 114

1      
NumberTitleIssue Date
7727558Polymeric delivery agents and delivery agent compounds
Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
06/01/2010
7700775Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
04/20/2010
7662771Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP)-1 compound or a melanocortin-4 receptor (MC4) agonist peptide
The present invention relates to novel compounds, methods, and formulations useful for the oral delivery of a GLP-1 compound or an MC4 agonist peptide. ...
02/16/2010
7553872Compounds and compositions for delivering active agents
Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
06/30/2009
7544833Methods for producing N-(8-[2-hydroxybenzoyl]-amino) caprylic acid
Disclosed are improved methods for the synthesis of N-(8-[2-hydroxybenzoyl]-amino)caprylic acid. Certain compounds have been found useful for preventing the formation of a colored impurity when included in an ester hydrolysis reaction. Conducting ester hydrolysis in...
06/09/2009
7390834Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents
Cyanophenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration, treatment of disease and preparation are provided as well. ...
06/24/2008
7309698Compositions for delivering bisphosphonates
Compounds and compositions for the delivery of bisphosphonates are provided. Methods of preparation, administration and treatment are provided as well. ...
12/18/2007
7297794Phenoxy amine compounds and compositions for delivering active agents
Phenoxy amine compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
11/20/2007
7279597Phenyl amine carboxylic acid compounds and compositions for delivering active agents
Phenyl amine carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
10/09/2007
7276534Carbon-substituted diketopiperazine delivery systems
Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions and admini...
10/02/2007
7262325Method of preparing salicylamides
The present invention provides a fast, high yield method for preparing salicylamide intermediates. The method comprises reacting a C4 or higher alkyl ester of salicylic acid or derivative thereof with at least one amine selected from the group consisting ...
08/28/2007
7227033Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate
The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ...
06/05/2007
72177038-(2-hydroxyphenoxy)octyldiethanolamine and salts thereof for delivery of active agents
The present invention provides 8-(2-hydroxyphenoxy)octyldiethanolamine) and salts thereof, compositions containing the same and one or more active agents, and methods of administering active agents with the same. The delivery agents of the present invention are well...
05/15/2007
7208178Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate
The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ...
04/24/2007
7208483Polymeric delivery agents and delivery agent compounds
Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
04/24/2007
7186414Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
03/06/2007
7151191Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
12/19/2006
7138546Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
11/21/2006
7129274Phenoxy carboxylic acid compounds and compositions for delivering active agents
Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
10/31/2006
7125910Compounds and compositions for delivering active agents
Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
10/24/2006
7115663Cyanophenoxy carboxylic acid compounds and compositions for delivering active agents
Cyanophenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration, treatment of disease and preparation are provided as well. ...
10/03/2006
7084279Oxadiazole compounds and compositions for delivering active agents
Oxadiazole compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
08/01/2006
7071214Compounds and compositions for delivering active agents
Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
07/04/2006
7067119Compounds and compositions for delivering active agents
Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration and methods of preparation of the modified amino a...
06/27/2006
7005141Oral drug delivery compositions and methods
The present invention relates to an oral drug delivery system, and in particular to modified amino acids and modified amino acid derivatives for use as a delivery system of sensitive agents such as bioactive peptides. The modified amino acids and derivatives can for...
02/28/2006
6991798Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
01/31/2006
6972300Compounds and compositions for delivering active agents
Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides, such as rhGH. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration, are provided, and methods of prepar...
12/06/2005
6960355Compounds and compositions for delivering active agents
Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
11/01/2005
6916489Active agent transport systems
Methods for transporting a biologically active agent across a cellular membrane or a lipid bilayer. A first method includes the steps of: (a) providing a biologically active agent which can exist in a native conformational state, a...
07/12/2005
6906030Carbon-substituted diketopiperazine delivery systems
Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions and admini...
06/14/2005
6900344Method of preparing alkylated salicylamides via a dicarboxylate intermediate
The present invention relates to a method of preparing an alkylated salicylamide from a protected and activated salicylamide via a dicarboxylated salicylamide intermediate. The present invention also relates to dicarboxylic salicylamide delivery agent compounds for ...
05/31/2005
6846844Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ...
01/25/2005
6699467Compounds and compositions for delivering active agents
Modified amino acid compounds useful in the delivery of active agents are provided. The active agents can be peptides. Methods of administration, such as oral, subcutaneous, sublingual, and intranasal administration and methods of preparation of the modif...
03/02/2004
6693208Compounds and compositions for delivering active agents
Amino acid derivative as carrier compounds and compositions which are useful in the delivery of active agents are provided. The active agents can be a peptide, mucopolysaccharide, carbohydrate, or lipid. Methods of administration, including oral administr...
02/17/2004
6693073Pulmonary delivery of active agents
The present invention provides methods for administering an active agent to an animal in need of the agent by the pulmonary route. This method comprises administering via the pulmonary route, a composition comprising (a) an active agent and (b)(i) an acyl...
02/17/2004
6663898Carbon-substituted diketopiperazine delivery systems
Compositions useful in the delivery of active agents are provided. These delivery compositions include (a) an active agent; and (b) a carrier of at least one mono-C-substituted or di-C-substituted diketopiperazine. Methods for preparing these compositions...
12/16/2003
6663887Compounds and compositions for delivering active agents
Modified amino acid compounds useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well....
12/16/2003
6646162Compounds and compositions for delivering active agents
Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well....
11/11/2003
6642411Compounds and compositions for delivering active agents
Carrier compounds and compositions therewith which are useful in the delivery of active agents are provided Methods of administration and preparation are provided as well....
11/04/2003
6627228Polymeric delivery agents and delivery agents compounds
Polymeric delivery agents, delivery agent compounds and compositions comprising them which are useful in the delivery of active agents are provided. Methods of administration and preparation are provided as well....
09/30/2003
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