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| Number | Title | Issue Date |
| 8110547 | Compositions for buccal delivery of parathyroid hormone Compositions and pharmaceutical formulations for buccally delivering parathyroid hormone comprising a) a delivery agent, b) a PTH component and, optionally, c) an antiresorptive agent are provided. ... | 02/07/2012 |
| 8039018 | Solid dosage form of wetted heparin The present invention relates to a solid pharmaceutical composition (such as a solid dosage form) comprising a delivery agent and wetted heparin. The inclusion of wetted heparin rather than un-wetted heparin in the solid pharmaceutical composition results in increas... | 10/18/2011 |
| 8030271 | Compositions and methods for buccal delivery of human growth hormone The present invention provides pharmaceutical compositions for buccal delivery of human growth hormone (hGH) comprising a delivery agent and hGH. The compositions of the present invention provide improved delivery of hGH compared to comparable oral compositions, res... | 10/04/2011 |
| 8026392 | Crystalline forms of the di-sodium salt of N-(5-Chlorosalicyloyl)-8-aminocaprylic acid The present invention relates to crystalline polymorphic forms of the di-sodium salt of N-(5-chlorosalicyloyl)-8-aminocaprylic acid, pharmaceutical compositions containing the same, methods of preparing the same, and methods for facilitating the delivery of active a... | 09/27/2011 |
| 8022048 | Method of treating vitamin B12 deficiency A novel method and composition for treating vitamin B12 deficiency mammals that fail to respond to oral vitamin B12 therapy. ... | 09/20/2011 |
| 8003697 | Disodium salts, monohydrates, and ethanol solvates for delivering active agents The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these deliver... | 08/23/2011 |
| 7977506 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 07/12/2011 |
| 7951971 | Phenoxy carboxylic acid compounds and compositions for delivering active agents Phenoxy carboxylic acid compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 05/31/2011 |
| 7947841 | Compounds, methods and formulations for the oral delivery of a glucagon-like peptide (GLP)-1 compound or a melanocortin-4 receptor (MC4) agonist peptide The present application relates to novel compounds, methods and formulations useful for the oral delivery of a glucagon like peptide-1 compound or a melanocortin 4 receptor agonist peptide. ... | 05/24/2011 |
| 7939494 | Method for administering GLP-1 molecules The invention relates to formulations that demonstrate the feasibility of oral absorption comprising glucose-like peptide-1 compounds and specified delivery agents, and to methods of stimulating GLP-1 receptor in a subject in need of such stimulation, by administrat... | 05/10/2011 |
| 7915314 | Disodium salts, monohydrates, and ethanol solvates for delivering active agents The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these deliver... | 03/29/2011 |
| 7893297 | Amorphous sodium 4-[4-chloro-2-hydroxybenzoyl)amino]butanoate The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ... | 02/22/2011 |
| 7744910 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provided as well. ... | 06/29/2010 |
| 7495030 | (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid and salts thereof and compositions containing the same for delivering active agents (5-(2-hydroxy-4-chlorobenzoyl) aminovaleric acid, salts thereof, and compositions containing the same for the delivery of active agents are provided. Methods of administration, treatment of disease and preparation are provided as well. ... | 02/24/2009 |
| 7462368 | Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino]butanoate The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ... | 12/09/2008 |
| 7429564 | Oral insulin therapy Pharmaceutical dosage forms for oral administration to a patient for the treatment of diabetes, comprising insulin and a delivery agent that facilitates insulin transport in a therapeutically effective amount to the bloodstream and that result in a lower incidence o... | 09/30/2008 |
| 7420085 | Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl) amino] butanoate The present invention relates to amorphous and polymorphic forms of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate and their use for facilitating the delivery of active agents, such as insulin, to a target. ... | 09/02/2008 |
| 7411084 | Method of preparing phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof via a dicarboxylate intermediate The present invention relates to a method of preparing a phenoxy alkanoic, alkenoic, or alkynoic acid or a salt thereof from a phenoxy containing compound via a dicarboxylate intermediate. The phenoxy alkanoic, alkenoic, and alkynoic acids and salts thereof prepared... | 08/12/2008 |
| 7384982 | Disodium salts, monohydrates, and ethanol solvates for delivering active agents The inventors have discovered that the disodium salt of certain delivery agents has surprisingly greater efficacy for delivering active agents than the corresponding monosodium salt. Furthermore, the inventors have discovered that the disodium salts of these deliver... | 06/10/2008 |
| 7384914 | Night-time oral insulin therapy A method for protection of a mammal that has impaired glucose tolerance or early stage diabetes mellitus from developing overt or insulin dependent diabetes comprises administering an orally effective dose of a pharmaceutical formulation comprising insulin at nightt... | 06/10/2008 |
| 7351741 | Compounds and compositions for delivering active agents Compounds and compositions for the delivery of active agents are provided. Methods of administration and preparation are provide as well. ... | 04/01/2008 |
