Assignee: Elan Corporation, plc

Location: Dublin, IE
No. of patents: 24

Number	Title	Issue Date
7135457	Random peptides that bind to gastro-intestinal tract (GIT) transport receptors and related methods This invention relates to proteins (e.g., peptides) that are capable of facilitating transport of an active agent through a human or animal gastro-intestinal tissue, and derivatives (e.g., fragments) and analogs thereof, and nucleotide sequences coding for said prot...	11/14/2006
6902742	Multiparticulate modified release composition The invention relates to a multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner. The multiparticulate modified release composition comprises an immediate release component and a modified release ...	06/07/2005
6830560	Automatic syringe A syringe comprises a barrel containing an internal cylindrical body containing a liquid and communicating with a delivery needle. The needle is covered before use by a removable sheath, and after the sheath is removed, the needle is concealed by a displaceable slee...	12/14/2004
6793936	Multiparticulate modified release composition The invention relates to a multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner. The multiparticulate modified release composition comprises an immediate release component and a modified release ...	09/21/2004
6780846	Membrane translocating peptide drug delivery system The present invention relates to a novel membrane translocating full-length peptide sequence, fragment, motif, derivative, analog or peptidomimetic thereof (MTLPs), to nucleotide sequences coding therefor, and to compositions comprising a MTLP-active agent complex a...	08/24/2004
6730325	Multiparticulate modified release composition The invention relates to a multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner. The multiparticulate modified release composition comprises an immediate release component and a modified release ...	05/04/2004
6699973	Antibodies to peptides that target GIT receptors and related methods The invention provides an antibody or antibody fragment specific to a domain of a GIT targeting agent, such as a polyclonal antibody, monoclonal antibody, chimeric antibody, single chain antibody, a Fab fragment or a Fab expression library. In particular,...	03/02/2004
6521737	Peptides which enhance transport across tissues and methods of identifying and using the same A method of identifying a peptide which permits or facilitates the transport of an active agent through a human or animal tissue. A predetermined amount of phage from a random phage library or preselected phage library is plated unto or brought into conta...	02/18/2003
6423334	Composition and method for enhancing transport across gastrointestinal tract cell layers A composition for enteral administration having a non-ionic vegetable oil GIT absorption enhancer capable of increasing the enteral absorbability of drugs, especially oral absorbability of hydrophilic and macromolecular drugs. The non-ionic vegetable oil ...	07/23/2002
6399100	Controlled release pharmaceutical compositions containing tiagabine Controlled release oral pharmaceutical preparations are provided which comprise a therapeutically effective amount of tiagabine or a pharmaceutically acceptable salt thereof dispersed in a rate controlling polymeric matrix comprising at least one rate con...	06/04/2002
6361938	Peptides which enhance transport across tissues and methods of identifying and using the same A method of identifying a peptide which permits or facilitates the transport of an active agent through a human or animal tissue. A predetermined amount of phage from a random phage library or a preselected phage library is administered in vivo or in situ...	03/26/2002
6346613	Composition and method for enhancing paracellular transport across cell layers A composition and method for enhancing paracellular transport across cell layers in an animal comprising an antisense oligonucleotide hybridizable with a region of the messenger RNA coding for the protein occludin which, when hybridized to the occludin mR...	02/12/2002
6275717	Device and method of calibrating and testing a sensor for in vivo measurement of an analyte A method of calibrating an analyte sensor in vivo, by providing a first predetermined stimulus to the sensor when the sensor is applied to a subject to produce a first sensor signal, measuring the first sensor signal, and determining a calibration functio...	08/14/2001
6261272	Needle for subcutaneous delivery of fluids A needle (10) for the delivery of a liquid to a subject comprises a shaft (11) having an internal surface defining a longitudinally extending internal bore open at one end (15) to receive a liquid supply, the other end (16) being sharpened for penetration...	07/17/2001
6228398	Multiparticulate modified release composition The invention relates to a multiparticulate modified release composition that in operation delivers an active ingredient in a pulsed or bimodal manner. The multiparticulate modified release composition comprises an immediate release component and a modifi...	05/08/2001
6186982	Subcutaneous drug delivery device with improved filling system A subcutaneous drug delivery device having a housing having an internal reservoir in communication with a drug delivery needle via a fluid path. An expandable chamber disposed adjacent to the reservoir forces drug from the reservoir to the needle when sup...	02/13/2001
6153220	Taste-masked formulations A taste-masked micromatrix powder in which the ratio of a cationic copolymer synthesized form dimethylaminoethyl methacrylate and neutral methacrylic acid esters compared to a drug having poor organoleptic properties is greater than 2 to 1, preferably 4 t...	11/28/2000
6110494	Cisapride mini-tablet formulations A sustained release cisapride oral dosage formulation suitable for once-daily administration comprises a plurality of mini-tablets containing cisapride or a salt thereof with an organic acid and capable of releasing cisapride at different sites along the ...	08/29/2000
6099504	Pre-filled injection delivery device A syringe (10) comprises a barrel (11) containing an internal cylindrical body (12) containing a liquid (14) and communicating with a delivery needle (15). The needle (15) is covered before use by a removable sheath (16), and after the sheath (16) is remo...	08/08/2000
6078842	Electrode and iontophoretic device and method An improved electrode and iontophoretic device and method where the electrode exhibits varied resistance. The electrode is made of a conductive material and applied to a flexible substrate. The variation in resistance can be achieved by varying the thickn...	06/20/2000
6066339	Oral morphine multiparticulate formulation An oral morphine multiparticulate formulation for once-daily administration to a patient, comprising sustained release particles each having a core containing water soluble morphine and an osmotic agent, the core being coated with a rate-controlling polym...	05/23/2000
6000548	Drug delivery kit and method of packaging the same An improved drug delivery kit and method of packaging the same. The method includes providing a tray having first and second recesses for receiving a drug delivery device and drug cartridge respectively, and an opening in the tray within the second recess...	12/14/1999
5997501	Intradermal drug delivery device An intradermal drug delivery device comprises a housing (301a, 301b) having a drug reservoir (312) therewithin and a gas generation chamber (313) separated from the reservoir (312) by a displaceable membrane (311). A microprocessor-controlled electrolytic...	12/07/1999
5925030	Orally administrable delivery device Oral drug delivery device having a housing with walls of water permeable material and having at least two chambers separated by a displaceable membrane. The first chamber receives drug and has an orifice through which the drug is expelled under pressure. ...	07/20/1999

PatentStorm

Quotables

PatentStorm News

Assignee: Elan Corporation, plc