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Assignee: Development Center for Biotechnology


Location: Taipei, TW
No. of patents: 33

NumberTitleIssue Date
7335303Zero-discharge of water glass effluents by alkaline biotreatment techniques
The present invention relates to the collection of alkalophilic/alkaline-tolerant microbes and use of said microbes in water glass wastewater treatment. The wastewater is treated directly with alkalophilic/alkaline-tolerant microbes cultured on granular activated ca...
02/26/2008
7153933Solid phase method for synthesis peptide-spacer-lipid conjugates, conjugates synthesized thereby and targeted liposomes containing the same
A solid phase synthesis method for preparing peptide-spacer-lipid conjugates, the peptide-spacer-lipid conjugates synthesized by the method, and liposomes containing the peptide-spacer-lipid conjugates. The present invention provides a convenient solid phase synthes...
12/26/2006
7033751Antigenic fragment of human T-lymphotropic virus
Antigenic fragments of human T-lymphotropic virus (HTLV), their fusion proteins with glutathione S-tranferase (GST) or thioredoxin (Thio), and a process for producing the fusion proteins thereof. The antigenic fragment of HTLV comprises the amino acid sequence of SE...
04/25/2006
6833458Practical syntheses of chiral trans-3, 4-disubstituted piperidines and the intermediates
A new method for the preparation of chiral 4-substituted 2-piperidinones, trans-3,4-disubstituted 2-piperidinones, and trans-3,4-disubstituted piperidines is invented. Chiral paroxetine can be obtained from a chiral trans-3,4-disubstituted piperidine intermediate in...
12/21/2004
6699720Interference-eliminating membranes, test strips, kits and methods for use in uric acid assay
The present invention relates to an interference-eliminating membrane for use in detecting uric acid in a sample, comprising a compound for inhibiting or shading uric acid interfering substances, or derivatives thereof, and a carrier having an absorption ...
03/02/2004
6616929Swine vesicular disease virus expression vectors
The invention relates to nucleic acids containing a nucleotide sequence encoding a polypeptide, the polypeptide having (1) the P2 and P3 regions of a swine vesicular disease virus polyprotein, and (2) an amino acid sequence heterologous to the polyprotein...
09/09/2003
6313294Process for preparing amides
The present invention provides a process for preparing an amide, which comprises reacting an amine with an ester in a molten form in the absence of a solvent....
11/06/2001
6313293Preparation of amides and quinazoline derivatives
The present invention relates to a process for the preparation of amides, comprising reacting amines with carboxylic acids in the presence of silicon amines. The present invention further relates to a process for the preparation of quinazoline derivatives...
11/06/2001
6287845Strains of streptomyces and relevant uses thereof
The invention relates to isolates of Streptomyces orientalis Y31014 and Streptomyces melanogenes Y31042-1 can be effectively control whiteflies. The invention also concerns a novel biopesticide and its use to control pests....
09/11/2001
6221396Oral cisapride dosage forms with an extended duration
The present invention provides sustained release oral solid dosage forms of cisapride by using a multi-particulate system, which are bioavailable and can provide efficient blood level of cisapride over 24 hours. Unit dosage forms of cisapride which compri...
04/24/2001
6218507Synthetic peptides for the detection of trimethylamine (TMA) and their detection method and device
The present invention describes a peptide and analogues thereof, which is a fragment of an olfactory receptor protein capable of selectively binding to trimethylamine so that they are useful for detecting trimethylamine. The present invention further describes...
04/17/2001
6200576Swine vesicular disease virus and mutant strains and preparation process and use thereof
The present invention relates to a gene of swine vesicular disease virus (SVDV) and the mutant strains of the gene, and the expression plasmids, the preparation process thereof. The invention also relates to a vaccine for use in the prophylaxis of swine v...
03/13/2001
6193964Strain of streptomyces, and relevant uses thereof
Disclosed is a new Streptomyces candidus strain, and relevant uses thereof....
02/27/2001
6183777Controlled release tacrine dosage form
Disclosed is a controlled release tacrine dosage form, which comprises: (a) a core; (b) an inner active layer comprising tacrine and a binder; (c) a release-controlling layer comprising one or more release-controlling-film-forming polymer; and (d) an active overcoa...
02/06/2001
6110480Method for preparing an environmentally compatable porous material comprising beneficial nematodes and the biotic preparations produced therefrom
The present invention teaches method for culturing nematode pesticidal compositions, to produce at a high yield, and generate biotic compositions that are effective as insecticides with high pesticidal activity and preventive effects....
08/29/2000
6083734Recombinant xylanase, the preparation and use of thereof
The present invention provides a genetically recombinant xylanase with high yield and good activity, and a process for the production of the recombinant xylanase. The present invention also provides the coding sequence of the recombinant sequence, vectors...
07/04/2000
6015704Mutant aspartase and the preparation thereof
Disclosed is a mutant aspartase comprising the amino acid sequence of a wild-type E. coli aspartase wherein the amino acid residue at one of positions 25, 123, 421 and 463 is substituted. Also disclosed is a process for preparing the above mutant aspartas...
01/18/2000
5889051Stabilization of prostaglandin drug
A stable solid dispersion of prostaglandin drug, particularly Misoprostol, (&#b1;)methyl 7-›3(଱)-hydroxy-2-ଲ-(4 (RS)-4-hydroxy-4-methyl-trans-1-octen-1-yl)-oxycyclopent-1଱-yl!hepta noate, comprising ammonio methacrylate copolymers. The a...
03/30/1999
5858735Process for producing trehalose
A process for obtaining trehalose by growing a fungus of the genus Pleurotus in a liquid or solid medium and purifying the trehalose produced by the fungus....
01/12/1999
5846705Nucleotide sequence of two circular SSDNA associated with banana bunchy top virus and method for detection of banana bunchy top virus
Nucleotide sequences of two circular single-stranded DNAs associated with Banana Bunchy Top Virus and the proteins encoded by the open reading frames in the nucleotide sequences are provided. A method for detecting Banana Bunchy Top Virus using the PCR te...
12/08/1998
5840991Antiatherosclerosis agents for lipid-lowering and antiperoxidative activity
The invention relates to novel compounds of formula (I) ##STR1## wherein R1 represents hydrogen, hydroxy or alkoxy; R2, R3, R4 and R5 may be hydrogen or alkyl; and n is 0,1 or 2; and the pharmaceutically a...
11/24/1998
57565161,2,3,4-tetrahydroisoquinoline derivatives and pharmaceutical composition thereof
The invention relates to compounds of formula (I) ##STR1## wherein R1 is an optional substituent any position of phenyl ring and is selected from halogen, --NO2, --NH2, --OH and --O--CR1-6 alkyl; --CH2...
05/26/1998
5723307Fluorogenic substrates for assay of angiotensin converting enzyme
Disclosed are new fluorogenic substrates for assay of angiotensin converting enzyme, a process for preparing them and methods for using them to assay angiotensin converting enzyme and to screen antihypertensive agents which inhibit angiotensin converting ...
03/03/1998
5629202Computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan
Disclosed is an automatic computer-controlled bioreactor system for enzymatic synthesis of L-tryptophan which comprises a bioreactor linked to a computer equipped with an on-line indole assay device, in which the computer controls the feeding of indole, p...
05/13/1997
5616713Process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine
A process of preparing 2-hydroxymethyl-3,5-dimethyl-4-methoxypyridine including the steps of acylating 2-methyl-1-penten-1-alkoxy-3-one to obtain 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone; ammonolyzing 2-alkoxycarbonyl-3,5-dimethyl-4-pyrone to obtain 2-...
04/01/1997
5504221Method for resolving racemic compounds
A method for resolving racemic dimethyl-4,4'-dimethoxy-5,6,5',6'-di(methylenedioxy)biphenyl-2,2'-dicarbox ylate ("DDB"), in which a chiral ଱-alkyl benzyl alcohol is used as the resolving agent. More specifically, racemic DDB is first hydrolyzed to ...
04/02/1996
5462863Isolation of Hepatitis B surface antigen from transformed yeast cells
A method for recovering hepatitis B surface antigen protein from transformed yeast cells including the steps of (i) obtaining an aqueous homogenate of the yeast cells; (ii) enriching the hepatitis B surface antigen protein in the homogenate with a protein...
10/31/1995
5360927Process for the preparation of monohydrated sodium phenylpyruvate
A process for the preparation of monohydrated sodium phenylpyruvate comprises reacting benzaldehyde with the stoichiometric quantity of hydantoin in the aqueous medium in the presence of a catalytic quantity of a primary or secondary amine at high tempera...
11/01/1994
5283066Method of stimulating an immune response by using a hapten
Disclosed is a method of stimulating an immune response by using a hapten. Haptens are adhered onto a solid phase support to form a complex. This complex can stimulate an immune response of an animal and the animal's lymphocytes. The solid phase supports ...
02/01/1994
5279946Process for the preparation of N-benzyloxycarbonyl-alpha-L-aspartyl-L-phenylalanine methyl ester
Disclosed is a process for the preparation of N-benzyloxycarbonyl-଱-L-aspartyl-L-phenylalanine methyl ester wherein a protease is used to catalyze the condensation reaction of N-benzyloxycarbonyl-L-aspartic acid with L-phenylalanine methyl ester in ...
01/18/1994
5250082Encapsulated structure for plant initiate material
Disclosed is an encapsulated structure for plant initiate material. Plant initiate material is encapsulated in a waterproof membrane coating or waterproof capsule, onto which water swellable polymeric material particles are partly embedded. This structure...
10/05/1993
5091089Microbial decolorization of wastewater
Present invention offers, for the first time, a biological approach through the use of white-rot fungi to the decolorization of dye wastewater. It is also applicable to other colored substances and/or their wastewater such as molasses. Because of its low ...
02/25/1992
5063244Process for the isolation of antifungal agents (5-methoxy-7-hydroxyflavan) from dragon's blood resin and its use in agriculture
5-methoxy-7-hydroxyflavan compound (I) was isolated and purified from Dragon's Blood resin. The purification process involves 50% ethanol soxhletion overnight and then fraction through silica column with a series of solvent elution. The purified compound ...
11/05/1991
 
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