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Patent No. 5508049

Pizza Pie With Concentric Rings of Crust

A pizza mold for forming a plurality of concentric raised ridges of dough (i.e., crust) on the surface of a pizza pie.

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Assignee: Deutsches Krebsforschungszentrum Stiftung des Offentlichen Rechts


Location: Heidelberg, DE
No. of patents: 80

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NumberTitleIssue Date
8142791Multi-modal cancer therapy using viral hitch-hiking
The present invention relates to an antibody fusion protein which specifically recognizes the VA, HN or F surface antigen of the New Castle Disease Virus (NDV), a surface molecule of a tumor-unspecific T cell or a surface molecule of a dendritic cell and an immunocy...
03/27/2012
8138313Treatment of tumors using specific anti-L1 antibody
The present invention relates to the anti-L1 monoclonal antibody 9.3 as well as to related antibodies or binding molecules and well as to the uses thereof, especially in tumor treatment. ...
03/20/2012
8008434Preparation of solid phase bound peptides or PNAs
The invention relates to a process for the preparation of at least one solid phase bound peptide. PNA or a chimera. ...
08/30/2011
8007813CD95-Fc fusion proteins
The invention relates to fusion proteins comprising at least a first domain and a second domain selected from a constant Fc immunoglobulin domain. ...
08/30/2011
7947462Methods for identifying Kremen polypeptide binding partners
The present invention relates to a composition useful for the diagnosis and therapy of diseases associated with aberrant expression of the gene encoding the receptor Kremen 1 and/or Kremen 2 e.g. tumors or diseases of the kidneys, bones and eyes, lipid and glucose m...
05/24/2011
7746470Optical scanning device and method of deriving same
The present invention relates to an optical scanning device that comprises a light source to emit a beam of light, and a beam splitter to split that beam into several beamlets, and further a first objective lens to direct said beamlets onto a focal plane wherein eac...
06/29/2010
7713712Antibodies active against a fusion polypeptide comprising a histidine portion
The present invention relates to an antibody active against a fusion polypeptide comprising a histidine portion, a process for the preparation thereof and its use. ...
05/11/2010
7700114Modified HPV E6 and E7 genes and proteins useful for vaccination
Described are DNA sequences encoding an E6 or E7 fusion protein of HPV, wherein said DNA sequences are characterized by a combination of the following features: original codons are exchanged by codons which lead to an enhanced translation in a mammalian cell, they c...
04/20/2010
7670601Diagnostic and therapeutic methods based on the L1 adhesion molecule for ovarian and endometrial tumors
A method is described for the diagnosis of an ovarian or endometrial tumor or for a prognosis, characterized in that the L1 level is determined in a patient sample, preferably via an anti L1 antibody, the presence of L1 being an indication of the presence of an ovar...
03/02/2010
7650343Data warehousing, annotation and statistical analysis system
The present invention relates to a database storage structure for the storage of a plurality of results from an experiment on a sample. The database storage structure includes a result storage table for storing the results from the experiment, one or more first anno...
01/19/2010
7618785Diagnostic and therapeutic methods based on the L1 adhesion molecule for ovarian and endometrial tumors
A method is described for the diagnosis of an ovarian or endometrial tumor or for a prognosis, characterized in that the L1 level is determined in a patient sample, preferably via an anti L1 antibody, the presence of L1 being an indication of the presence of an ovar...
11/17/2009
6706713Conjugate for treating inflammatory infectious and/or skin diseases
This invention relates to the use of a conjugate comprising an active substance and a native protein which is not recognized as foreign protein for the production of a pharmaceutical preparation for treating and/or diagnosing inflammatory, infectious and/or skin dis...
03/16/2004
7354714Production and applications for polyvalent vaccines against diseases caused by papilloma viruses
A vaccine against disease caused by papilloma viruses is described in certain embodiments, as well as certain vectors, obtainable by the following methods: (a) one or more expression vectors that contain the DNA code for a structural protein of papilloma viruses or ...
04/08/2008
7320861Polyvalent vaccine against diseases caused by papilloma viruses, method for the production and the use thereof
A vaccine against disease caused by papilloma viruses is described in certain embodiments, as well as certain vectors, obtainable by the following methods: (a) one or more expression vectors that contain the DNA code for a structural protein of papilloma viruses or ...
01/22/2008
7267825Parvovirus vectors and their use
This invention relates to a parvovirus vector having a parvovirus DNA excisable from the vector DNA in a parvovirus-permissive cell, the parvovirus DNA having a left terminus which comprises a parvovirus minimal origin of replication, and a system comprising the par...
09/11/2007
7239400Method and apparatus for detecting the position and the orientation of an interventional device
The invention relates to a method and an apparatus for measuring the position and the orientation of an interventional device within a magnetic resonance imaging apparatus, the magnetic resonance image apparatus providing a static magnetic field B0 and ma...
07/03/2007
7157246RNA polymerase I transcription factor TIF-IA
The present invention relates to an RNA polymerase I transcription factor TIF-IA and proteins related thereto, whose concentration and/or activity are correlated with the cell proliferation rate, and to DNA sequences encoding these proteins. The present invention al...
01/02/2007
7148341AAV DNA comprising helper virus sequences
The present invention relates to an AAV DNA having helper virus sequences which are necessary for developing AAV viral particles, a system containing such a DNA and the use of both. ...
12/12/2006
7145000Markable compounds for easy synthesis of 3'-[F] fluoro-3'-deoxynucleotides, and method for their production
What is described are compounds wherein R represents Br, I or R1—SO3, where R1 is an unsubstituted or substituted C1–C5-alkyl gr...
12/05/2006
7132674Collimator for high-energy radiation and program for controlling said collimator
The invention relates to a collimator (1) for defining a beam of energetic rays (2) which is emitted from an essentially punctiform radiation source (3) and is oriented onto an object (1) to be treated. The collimator is especially used f...
11/07/2006
6993112Device for performing and verifying a therapeutic treatment and corresponding computer program and control method
The invention relates to a device for performing and verifying therapeutic radiation. An x-ray beam (4) is arranged across from a target volume (3) of the beam source (11) for the high-energy beam (1) in such a way that the beams (1, 4...
01/31/2006
6958395Method for producing water-soluble saccharide conjugates and saccharide mimetics by Diels-Alder reaction
The present invention relates to a method by which saccharide compounds can be prepared in a very easy way. This method comprises the steps of: (a) attaching at least one saccharide to a cyclic or acyclic diene, (b) reacting the saccharide-...
10/25/2005
6953695Device and method for fluorescence correlation spectroscopy, especially for multi-color fluorescence correlation spectroscopy
A device for fluorescence correlation spectroscopy, especially for multicolor fluorescence correlation spectroscopy, in which light rays are focused in a transparent medium located in a sample vessel. Such device includes a vessel holder in which at least two sample...
10/11/2005
6927281Adeno-associated virus-its diagnostic use with early abortion
The present invention relates to a method of detecting a causative agent of the so-called spontaneous early abortion by investigating patients' samples for the presence of adeno-associated virias DNA (AAV DNA), or AAV antigen or antibodies, preferably of the IgM typ...
08/09/2005
6905724Derivatization of support surfaces
The present invention relates to a process for derivatizing supports on a carriers, wherein a functional group is activated on a support surface by reaction with an activating reagent and then reacted with an amine component. The invention also relates to a support ...
06/14/2005
6891033Labelling compounds for the simple synthesis of 3'-[18F]fluoro-3'-deoxythymidine and a method for the production thereof
The application relates to compounds that are suitable as labelable precursors for synthesis of 3′-[18F]fluoro-3′-deoxythymidine and that have formula (1), in which R d...
05/10/2005
6812209Conjugate consisting of an active substance and a non-exogenous native protein
This invention relates to a conjugate which consists of an active substance and a native protein which is not regarded as exogenous and distinguish itself in that an intracellulary cleavable linker is present between the active substance and the protein. In a...
11/02/2004
6790940Antibodies active against a fusion polypeptide comprising a histidine portion
The present invention relates to an antibody active against a fusion polypeptide comprising a histidine portion, a process for the preparation thereof and its use. ...
09/14/2004
6756492Nucleoside derivatives with photo-unstable protective groups
The present invention relates to nucleoside derivatives having photolabile protective groups of general formula (I) in which R1=H, NO2, CN, OCH3, halogen, an alkyl, alkoxy or alkox...
06/29/2004
6743423Use of adeno-associated viruses for decreasing the radiotherapy-induced or chemotherapy- induced resistance in cancer patients
The invention relates to the use of adeno-associated viruses for decreasing the radiotherapy-induced or chemotherapy-induced resistance in patients who suffer from a cancer which is to be treated by radiotherapy or chemotherapy. ...
06/01/2004
6730483Phagemid for antibody screening
A phagemid has been constructed that expresses an antibody fused to coliphage pIII protein. The phagemid is suitable for selecting specific antibodies from large gene libraries with small quantities of antigen. The antibody-pIII gene can be strongly repressed, so th...
05/04/2004
6720304Conjugate comprising a folic acid antagonist and a carrier
The invention relates to conjugates comprising a D-enantiomer of a folic acid antagonist and a carrier. Furthermore, the invention relates to the production of such conjugates as well as their use. ...
04/13/2004
6711237Contour collimator for use in radiotherapy
A contour collimator for radiation therapy has a plurality of diaphragm elements that are movable with respect to each other by means of drive units. The diaphragm elements of the invention are supported only on the side near the drive units for ease of movement. Th...
03/23/2004
6696694Displacement detecting element
The invention relates to a displacement-detecting element (1) comprising a measuring resistance (2), voltage source (3) and a displacement-dependent voltage pick off (4). The measuring resistance (2) is embodied in the form of a strip. The length of the r...
02/24/2004
6696547Mutant DEDD proteins for regulating apoptosis
The invention relates to a protein for regulating apoptosis and to a nucleic acid encoding the protein. The protein and nucleic acids are useful in the regulation of apoptosis, and in methods for diagnosing or detecting apoptosis. The invention also relat...
02/24/2004
6673544Method for the light-controlled synthesis of biochips
The present invention relates to a method for the photolithographic synthesis of biochips in which photolabile protective groups of the 2-(2-nitrophenyl)ethyl type are used, whereby the irradiation step that is common in the photolithographic chip synthes...
01/06/2004
6610473Peptides for inhibiting HPV E6-proteins
The present invention relates to peptides suited for inhibiting HPV-E6 proteins, DNAs encoding them and the use of both, particularly for eliminating HPV tumor cells....
08/26/2003
6593105Prion propagation inhibition by dominant-negative prion protein mutants
The present invention relates to a vector which is suitable for gene prophylaxis/gene therapy, containing a nucleic acid fragment coding for a mutated prion protein. The invention further relates to a vaccination agent which contains the vector in additio...
07/15/2003
6586735Method for detecting an element in a sample
A method for detecting an element in a sample using a transmission electron microscope to measure a first image of the intensities of the sample at an energy loss in the range of the element signal. The background at various points is determined in a comp...
07/01/2003
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