Assignee: Daiichi Suntory Pharma Co., Ltd.

Location: Tokyo, JP
No. of patents: 23

Number	Title	Issue Date
7122543	Substituted benzoic acid derivatives having NF-κB inhibiting action A substituted benzoic acid derivative which is represented by the following formula (I) and has an NF-κB inhibiting action (in the formula, R3, R4 and R5 each independently represents a hydrogen atom, an alkyl group having 1 to 6 ca...	10/17/2006
7064124	NF-κB inhibitor containing substituted benzoic acid derivative as active ingredient A NF-κB inhibitor represented by the following formula (I) is provided: ...	06/20/2006
7057036	Pyrrolothiazine and pyrrolothiazepine compounds having serotonin-2 receptor antagonistic and alpha-1-blocking action A pyrrolesulfonamide derivative having the following formula (I): wherein the ring P represented by is a pyrrole ring having the following structure:	06/06/2006
7026293	Treatment or prophylaxis of ischemic heart disease The present invention provides a pharmaceutical composition and a method for reducing an infarct region resulting from the ischemic necrosis of cells, especially, a pharmaceutical composition and a method for suppressing ischemia-reperfusion injury in the treatment ...	04/11/2006
6943196	NF-κB inhibitor comprising phenylmethyl benzoquinone as the active ingredient An NF-κB inhibitor having as an active ingredient a benzoquinone derivative represented by the general formula (1) wherein R1, R2, and R3 are each independently H, alkyl having 1 to 5 carbons, or alkoxy having 1 to 5 carbons; R...	09/13/2005
6921766	Blood vessel lipid deposition-preventive agent comprising chymase-inhibitor There is provided a preventive or therapeutic agent for diseases accompanied by abnormal vascular function in which lipid deposition in the blood vessel is involved, said agent comprising a chymase inhibitor as an active ingredient. As the chymase inhibitor, ...	07/26/2005
6900202	Di-substituted imineheterocyclic compounds There is provided di-substituted iminoheterocyclic compounds of the following formula (I): in which, A is optionally substituted alkyl group, optionally substituted aryl group ...	05/31/2005
6867297	Process for synthesizing 4-substituted azetidinone derivatives An azetidinone derivative represented by the general formula (1) (wherein OR1 is a protected hydroxyl group; R2 is a substituted or unsubstituted alkyl group, a substituted or unsubstituted alkeny...	03/15/2005
6867214	Quinazoline derivatives and pharmaceutical applications thereof A quinazoline derivative having formula (1) and a pharmaceutically acceptable salt thereof: wherein the ring A represents an aryl group, which derivative has a chymase inhibitory acti...	03/15/2005
6838470	Arylpiperidinopropanol and arylpiprazinopropanol derivatives and pharmaceuticals containing the same A compound having the formula (I) or its salt, hydrate, hydrate salt or solvate: wherein R1 to R4 independently represent H, halogen, OH, alkoxy, optionally substituted alkyl, aryl, or aralkyl gro...	01/04/2005
6743913	Pyrrolothiazine and pyrrolothiazepine compounds having serotonin-2 receptor antagonistic and α-1-blocking action A pyrrolesulfonamide compound having the following formula (I): wherein the ring P represented by is a pyrrole ring having the following structure:	06/01/2004
6734180	NF-κB inhibitor comprising an indan derivative as an active ingredient An inhibitor of NF-κB comprising as an active ingredient an indan derivative represented by the general formula (I) or a salt thereof. ...	05/11/2004
6713634	Pyrroloazepine derivatives A method of effecting serotonin-2-receptor antagonism in a mammal in need thereof, which includes administering to the mammal an effective amount of the compound of the formula (I), or a pharmaceutically acceptable salt thereof: ...	03/30/2004
6706734	Arylpiperidinol and arylpiperidine derivatives and pharmaceuticals containing the same A pharmaceutical composition, especially a pharmaceutical composition for the alleviation or treatment of symptoms due to ischemic diseases and symptoms derived from seizures, epilepsy, and migraine, and a Ca2+ overload suppressant, containing an arylpipe...	03/16/2004
6706865	Process for preparing flavonoids A simple and easy process for preparing pharmacologically useful flavonoid compound having reductase inhibitory effect, active oxygen extinguishing effect, carcinogenesis promotion inhibitory effect, anti-inflammatory effect, and so on. Particularly, a process for p...	03/16/2004
6703421	Methods of using phenylmethylbenzoquinone and hydroquinone compounds for treatment of myocarditis, dilated cardiomyopathy and heart failure A method for prevention or treating myocarditis, dilated cardiomyopathy and heart failure comprising administering to a patient in need of such treatment a NF-.kappa.B inhibitor in a therapeutically effective amount, wherein said NF-.kappa.B inhibitor is ...	03/09/2004
6677344	Chymase inhibitor for the treatment of eosinophilia A chymase inhibitor for the prevention or treatment of diseases involving an increase of eosinophils, as the effective ingredient, is disclosed, suppress the progress of the disease and to prevent progression of complications, wherein the chymase inhibito...	01/13/2004
6664251	Benzothiazine derivative Disclosed are benzothiazine derivatives represented by the following formula (I): ##STR1## wherein the dashed line indicates the presence or absence of a bond; Z represents one of the following groups: ##STR2## in which R1 and R2	12/16/2003
6632943	Process for production of optically active pyrroloazepine derivatives It is provided a method for preparing the pyrroloazepine derivatives, especially in optically active form useful as drugs, by low-priced and simple method and in industrial applicable scale, represented by the following formula (I): ##STR1## wher...	10/14/2003
6624314	Pyrrolothiazine and pyrrolothiazepine compounds having serotonin-2 receptor antagonistic and alpha-1-blocking action A pyrrolesulfonamide derivative having the following formula (I): ##STR1## wherein the ring P represented by ##STR2## is a pyrrole ring having the following structure: ##STR3## wherein R represents alkyl, cycloalkyl, cycloalkylalkyl or aralky...	09/23/2003
6624308	Method of production and method of separation of 2,4'-dipyridyl derivatives and methods of production of benzoxazepine derivatives and salts thereof A method of production of 2,4'-dipyridyl derivatives by a cross coupling reaction of a 2-halopyridine derivative and a 4-halopyridine using a nickel complex catalyst and a method of separation of a 2,4'-dipyridyl derivative from a mixture of dipyridyl iso...	09/23/2003
6602681	Enzymatic production of a C-terminal ଱-amidated peptide or protein A C-terminal ଱-amidating enzyme of Xenopus laevis and precursor thereof produced by a recombinant DNA technique; a DNA coding for the enzyme or precursor thereof; a plasmid containing the DNA; a host organism transformed with the plasmid; a process ...	08/05/2003
6583296	Pyrrolothiazine and pyrrolothiazepine compounds having serotonin-2 receptor antagonistic and ଱-1-blocking action A pyrrolesulfonamide compound having the following formula (I): ##STR1## wherein the ring P represented by ##STR2## is a pyrrole ring having the following structure: ##STR3## wherein A represents alkylene, alkenylene or alkynylene; and Y represents a ...	06/24/2003

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Assignee: Daiichi Suntory Pharma Co., Ltd.